Xiaoyi Fan
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View article: Title：Targeting DNA Fragment Extrusion: A New Therapeutic Avenue for CCl4-Induced Hepatic Injury
Title：Targeting DNA Fragment Extrusion: A New Therapeutic Avenue for CCl4-Induced Hepatic Injury Open
Liver injury constitutes a significant threat to human health. The carbon tetrachloride (CCl 4 )-induced liver injury model is the most extensively utilized animal model. For the first time, in situ hybridization chain reaction …
View article: Bridging Theory and Practice: The Pedagogical Value of Subject Competitions in Undergraduate Business Education
Bridging Theory and Practice: The Pedagogical Value of Subject Competitions in Undergraduate Business Education Open
Traditional pedagogical models in undergraduate business education often face challenges in effectively bridging the gap between academic theory and real-world professional practice. This article examines the increasingly significant role …
View article: Targeting DNA Fragment Extrusion: A New Therapeutic Avenue for CCL4-Induced Hepatic Injury
Targeting DNA Fragment Extrusion: A New Therapeutic Avenue for CCL4-Induced Hepatic Injury Open
Liver injury constitutes a significant threat to human health. The carbon tetrachloride (CCL₄)-induced liver injury model is the most extensively utilized animal model. For the first time, in situ hybridization chain reaction (HCR) was uti…
View article: Ptbp1 Knockdown in Glial Cells Promotes Motor and Sensory Function Recovery After Peripheral Nerve Injury
Ptbp1 Knockdown in Glial Cells Promotes Motor and Sensory Function Recovery After Peripheral Nerve Injury Open
Background: Peripheral nerve injury (PNI) frequently causes persistent sensory and motor deficits with limited therapeutic options. While Ptbp1‐mediated astrocyte reprogramming shows promise in central nervous system repair, its role in PN…
View article: SIRT3 is required for the protective function of ketogenic diet on neural inflammation and neuropathic pain
SIRT3 is required for the protective function of ketogenic diet on neural inflammation and neuropathic pain Open
Chronic neuroinflammation is a key pathological feature of neuropathic pain. The ketogenic diet (KD) has demonstrated potential to reduce neuronal excitability and alleviate inflammation in epilepsy, yet its effects and precise mechanisms …
View article: Groundwater Level Prediction for Landslides Using an Improved TANK Model Based on Big Data
Groundwater Level Prediction for Landslides Using an Improved TANK Model Based on Big Data Open
Geological conditions and rainfall intensity are two primary factors that can induce changes in groundwater level, which are one of the major triggering causes of geological disasters, such as collapse, landslides, and debris flow. In view…
View article: Residual biliary intraepithelial neoplasia without malignant transformation at resection margin for perihilar cholangiocarcinoma does not require expanded resection: a dual center retrospective study
Residual biliary intraepithelial neoplasia without malignant transformation at resection margin for perihilar cholangiocarcinoma does not require expanded resection: a dual center retrospective study Open
View article: A Two-Stage Online Algorithm for EV Charging Station Energy Management and Carbon Trading
A Two-Stage Online Algorithm for EV Charging Station Energy Management and Carbon Trading Open
The increasing electric vehicle (EV) adoption challenges the energy management of charging stations (CSs) due to the large number of EVs and the underlying uncertainties. Moreover, the carbon footprint of CSs is growing significantly due t…
View article: A Hydrodynamic‐Based Physical Unified Modeling for Simulating Shallow Landslide Local Failures, Mass Release and Debris Flow Run‐Out Extent Behavior
A Hydrodynamic‐Based Physical Unified Modeling for Simulating Shallow Landslide Local Failures, Mass Release and Debris Flow Run‐Out Extent Behavior Open
Accurate prediction of shallow landslide occurrence and the subsequent motion range after transformation into debris flows is crucial for reducing disaster‐induced losses. The use of Cellular Automata‐based (CA) hydrodynamic models has see…
View article: Changes in SLITRK1 Level in the Amygdala Mediate Chronic Neuropathic Pain-Induced Anxio-Depressive Behaviors in Mice
Changes in SLITRK1 Level in the Amygdala Mediate Chronic Neuropathic Pain-Induced Anxio-Depressive Behaviors in Mice Open
Background: Comorbid chronic neuropathic pain (NPP) and anxio-depressive disorders (ADD) have become a serious global public-health problem. The SLIT and NTRK-like 1 (SLITRK1) protein is important for synaptic remodeling and is highly expr…
View article: The Analysis of Impact on Fire Resistance of Mortise-tenon Joint in Different Connection Mode
The Analysis of Impact on Fire Resistance of Mortise-tenon Joint in Different Connection Mode Open
In order to analysis of impact on fire resistance of mortise-tenon joint in different connection mode, four types of mortise-tenon Joints models are made by Pinus yunnanensis. And the combustion phenomena and carbonization of mortise-tenon…
View article: An Analysis of the Correct Use of Female Gaze from the Perspective of Gaze Theory -- A Case study of Portrait of a Lady on Fire
An Analysis of the Correct Use of Female Gaze from the Perspective of Gaze Theory -- A Case study of Portrait of a Lady on Fire Open
Feminism is currently popular, and there are an increasing number of feminist films attempting to promote this idea. Some scholars have expanded the theory of gaze into feministic fields, most notably Laura Mulvey, who proposed the concept…
View article: Low-Stiffness Hydrogels Promote Peripheral Nerve Regeneration Through the Rapid Release of Exosomes
Low-Stiffness Hydrogels Promote Peripheral Nerve Regeneration Through the Rapid Release of Exosomes Open
A hydrogel system loaded with mesenchymal stem cell–derived exosome (MSC-Exos) is an attractive new tool for tissue regeneration. However, the effect of the stiffness of exosome-loaded hydrogels on tissue regeneration is unclear. Here, the…
View article: BRD4 Inhibition Attenuates Inflammatory Pain by Ameliorating NLRP3 Inflammasome-Induced Pyroptosis
BRD4 Inhibition Attenuates Inflammatory Pain by Ameliorating NLRP3 Inflammasome-Induced Pyroptosis Open
Chronic pain, such as persistent inflammatory pain, remains a public health problem that has no effective treatment at present. Bromodomain-containing protein 4 (BRD4) inhibition, induced by JQ1 injection or BRD4 knockdown, has been used t…
View article: MicroRNA-125b exerts antitumor functions in cutaneous squamous cell carcinoma by targeting the STAT3 pathway
MicroRNA-125b exerts antitumor functions in cutaneous squamous cell carcinoma by targeting the STAT3 pathway Open
View article: Applied Research on Chinese Online Teaching for International Students During the New Coronary Epidemic
Applied Research on Chinese Online Teaching for International Students During the New Coronary Epidemic Open