Xiaoying Wan
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View article: Temporal genomic heterogeneity guiding individualized therapy in recurrent non-small cell lung cancer
Temporal genomic heterogeneity guiding individualized therapy in recurrent non-small cell lung cancer Open
Introduction Despite the benefit of adjuvant systemic therapy for patients with resected non-small cell lung cancer (NSCLC), the risk of postoperative recurrence remains high. Our objective was to characterize temporal genetic heterogeneit…
View article: Exercise identity, exercise behavior and mobile phone addiction: A cross-sectional mediation study with a sample of rural left-behind children in China
Exercise identity, exercise behavior and mobile phone addiction: A cross-sectional mediation study with a sample of rural left-behind children in China Open
To evaluate the relationships among exercise identity, exercise behavior and mobile phone addiction in 516 left-behind children in rural China (48.06% boys; Mage = 12.13 ± 1.95, range 8-16). Specifically, cross-sectional design was carried…
View article: Factors Influencing the Mental Health of Left-behind Children in Rural Areas
Factors Influencing the Mental Health of Left-behind Children in Rural Areas Open
The problem of left-behind children in rural areas is in existence for many years. Notably, their psychological well-being is the most concerned issue. Scholars previously devoted a great deal of efforts to exploring the causes of the psyc…
View article: Impact of Carbon Sequestration by Terrestrial Vegetation on Economic Growth: Evidence from Chinese County Satellite Data
Impact of Carbon Sequestration by Terrestrial Vegetation on Economic Growth: Evidence from Chinese County Satellite Data Open
Land vegetation plays an important role in reducing greenhouse gas emissions and stabilizing atmospheric CO2 concentration. However, the impact of carbon sequestration of terrestrial vegetation on economic growth has not yet been reported …
View article: DNMT3A governs tyrosine kinase inhibitors responses through IAPs and in a cell senescence-dependent manner in non-small cell lung cancer.
DNMT3A governs tyrosine kinase inhibitors responses through IAPs and in a cell senescence-dependent manner in non-small cell lung cancer. Open
Patients with non-small cell lung cancer (NSCLC) treated with tyrosine kinase inhibitors (TKIs) inevitably exhibit drug resistance, which diminishes therapeutic effects. Nonetheless, the molecular mechanisms of TKI resistance in NSCLC rema…
View article: Additional file 1 of Exosomes derived from M2 type tumor-associated macrophages promote osimertinib resistance in non-small cell lung cancer through MSTRG.292666.16-miR-6836-5p-MAPK8IP3 axis
Additional file 1 of Exosomes derived from M2 type tumor-associated macrophages promote osimertinib resistance in non-small cell lung cancer through MSTRG.292666.16-miR-6836-5p-MAPK8IP3 axis Open
Additional file 1: Table S1. All differentially expressed miRNAs between the exosomes isolated from the sensitive and resistant plasma with the thresholds of |log2Fold change (FC)|> 1 and false discovery rate (FDR) < 0.05.
View article: How Perturbated Metabolites in Diabetes Mellitus Affect the Pathogenesis of Hypertension?
How Perturbated Metabolites in Diabetes Mellitus Affect the Pathogenesis of Hypertension? Open
The presence of hypertension (HTN) in type 2 diabetes mellitus (DM) is a common phenomenon in more than half of the diabetic patients. Since HTN constitutes a predictor of vascular complications and cardiovascular disease in type 2 DM pati…
View article: The Effects of Vinegar Processing on the Changes in the Physical Properties of Frankincense Related to the Absorption of the Main Boswellic Acids
The Effects of Vinegar Processing on the Changes in the Physical Properties of Frankincense Related to the Absorption of the Main Boswellic Acids Open
Boswellic acids (BAs), as the main components of frankincense, exhibit notable anti-inflammatory properties. However, their pharmaceutical development has been severely limited by their poor oral bioavailability. Traditional Chinese medici…