Xiaoyun Xing
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View article: Cross-tissue molecular responses in the liver and blood after toxicant exposures
Cross-tissue molecular responses in the liver and blood after toxicant exposures Open
Exposure to toxic substances, particularly early in life, can perturb epigenomic marks linked to disease susceptibility. Human studies of environmental exposures often rely on surrogate tissues such as blood, but toxicant accumulation diff…
View article: Comprehensive Transcriptomic and Epigenomic Insights into Environmental Toxicant Exposures: The TaRGET II Resource
Comprehensive Transcriptomic and Epigenomic Insights into Environmental Toxicant Exposures: The TaRGET II Resource Open
Environmental exposures to toxic chemicals can profoundly alter the transcriptome and epigenome in both humans and animals, contributing to disease development across the lifespan. To elucidate how early-life exposure to toxicants exerts s…
View article: Glutathione/Cysteine Dual‐Consuming Prodrug Nanoassemblies for Potentiated Gas‐Photodynamic Therapy
Glutathione/Cysteine Dual‐Consuming Prodrug Nanoassemblies for Potentiated Gas‐Photodynamic Therapy Open
Tuning the oxidative stress‐defense system plays a vital role in the treatment of breast tumors. In this study, a pyropheophorbide‐a (PPa)‐based prodrug nanoassembly is constructed by linking PPa with furoxan, a cysteine‐depleting nitric o…
View article: EPCO-08. EPIGENETIC THERAPY POTENTIATES TRANSPOSABLE ELEMENT TRANSCRIPTION TO CREATE TUMOR-ENRICHED ANTIGENS IN GLIOBLASTOMA
EPCO-08. EPIGENETIC THERAPY POTENTIATES TRANSPOSABLE ELEMENT TRANSCRIPTION TO CREATE TUMOR-ENRICHED ANTIGENS IN GLIOBLASTOMA Open
Epigenetic treatment has been studied as a means to augment anti-tumor immune cell activity by increasing the expression of antiviral response genes. Previous studies, including our own, have revealed an additional consequence of epigeneti…
View article: Cis-regulatory evolution of the recently expanded Ly49 gene family
Cis-regulatory evolution of the recently expanded Ly49 gene family Open
Comparative genomics has revealed the rapid expansion of multiple gene families involved in immunity. Members within each gene family often evolved distinct roles in immunity. However, less is known about the evolution of their epigenome a…
View article: Non-Small Cell Lung Cancer Epigenomes Exhibit Altered DNA Methylation in Smokers and Never-Smokers
Non-Small Cell Lung Cancer Epigenomes Exhibit Altered DNA Methylation in Smokers and Never-Smokers Open
Epigenetic alterations are widespread in cancer and can complement genetic alterations to influence cancer progression and treatment outcome. To determine the potential contribution of DNA methylation alterations to tumor phenotype in non-…
View article: Supplementary Table from Developmental Pathways Are Epigenetically Reprogrammed during Lung Cancer Brain Metastasis
Supplementary Table from Developmental Pathways Are Epigenetically Reprogrammed during Lung Cancer Brain Metastasis Open
Supplementary Table from Developmental Pathways Are Epigenetically Reprogrammed during Lung Cancer Brain Metastasis
View article: Supplementary Table from Developmental Pathways Are Epigenetically Reprogrammed during Lung Cancer Brain Metastasis
Supplementary Table from Developmental Pathways Are Epigenetically Reprogrammed during Lung Cancer Brain Metastasis Open
Supplementary Table from Developmental Pathways Are Epigenetically Reprogrammed during Lung Cancer Brain Metastasis
View article: Supplementary Table from Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a <i>TP53</i>-Dependent Manner
Supplementary Table from Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a <i>TP53</i>-Dependent Manner Open
Supplementary Table from Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a TP53-Dependent Manner
View article: Supplementary Figure from Developmental Pathways Are Epigenetically Reprogrammed during Lung Cancer Brain Metastasis
Supplementary Figure from Developmental Pathways Are Epigenetically Reprogrammed during Lung Cancer Brain Metastasis Open
Supplementary Figure from Developmental Pathways Are Epigenetically Reprogrammed during Lung Cancer Brain Metastasis
View article: Supplementary Figure from Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a <i>TP53</i>-Dependent Manner
Supplementary Figure from Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a <i>TP53</i>-Dependent Manner Open
Supplementary Figure from Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a TP53-Dependent Manner
View article: Supplementary Table from Developmental Pathways Are Epigenetically Reprogrammed during Lung Cancer Brain Metastasis
Supplementary Table from Developmental Pathways Are Epigenetically Reprogrammed during Lung Cancer Brain Metastasis Open
Supplementary Table from Developmental Pathways Are Epigenetically Reprogrammed during Lung Cancer Brain Metastasis
View article: Supplementary Data from Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a <i>TP53</i>-Dependent Manner
Supplementary Data from Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a <i>TP53</i>-Dependent Manner Open
Supplementary Data from Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a TP53-Dependent Manner
View article: Supplementary Data from Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a <i>TP53</i>-Dependent Manner
Supplementary Data from Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a <i>TP53</i>-Dependent Manner Open
Supplementary Data from Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a TP53-Dependent Manner
View article: Supplementary Table from Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a <i>TP53</i>-Dependent Manner
Supplementary Table from Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a <i>TP53</i>-Dependent Manner Open
Supplementary Table from Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a TP53-Dependent Manner
View article: Supplementary Table from Developmental Pathways Are Epigenetically Reprogrammed during Lung Cancer Brain Metastasis
Supplementary Table from Developmental Pathways Are Epigenetically Reprogrammed during Lung Cancer Brain Metastasis Open
Supplementary Table from Developmental Pathways Are Epigenetically Reprogrammed during Lung Cancer Brain Metastasis
View article: Supplementary Table from Developmental Pathways Are Epigenetically Reprogrammed during Lung Cancer Brain Metastasis
Supplementary Table from Developmental Pathways Are Epigenetically Reprogrammed during Lung Cancer Brain Metastasis Open
Supplementary Table from Developmental Pathways Are Epigenetically Reprogrammed during Lung Cancer Brain Metastasis
View article: Data from Developmental Pathways Are Epigenetically Reprogrammed during Lung Cancer Brain Metastasis
Data from Developmental Pathways Are Epigenetically Reprogrammed during Lung Cancer Brain Metastasis Open
Non–small cell lung cancer (NSCLC) is one of the most commonly diagnosed and deadliest cancers worldwide, with roughly half of all patients initially presenting with both primary and metastatic disease. While the major events in the metast…
View article: Supplementary Table from Developmental Pathways Are Epigenetically Reprogrammed during Lung Cancer Brain Metastasis
Supplementary Table from Developmental Pathways Are Epigenetically Reprogrammed during Lung Cancer Brain Metastasis Open
Supplementary Table from Developmental Pathways Are Epigenetically Reprogrammed during Lung Cancer Brain Metastasis
View article: Supplementary Data from Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a <i>TP53</i>-Dependent Manner
Supplementary Data from Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a <i>TP53</i>-Dependent Manner Open
Supplementary Data from Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a TP53-Dependent Manner
View article: Supplementary Table from Developmental Pathways Are Epigenetically Reprogrammed during Lung Cancer Brain Metastasis
Supplementary Table from Developmental Pathways Are Epigenetically Reprogrammed during Lung Cancer Brain Metastasis Open
Supplementary Table from Developmental Pathways Are Epigenetically Reprogrammed during Lung Cancer Brain Metastasis