Xiao Lin
YOU?
Author Swipe
Research on the Application of Leather Materials in Elderly Care Products Open
As the population ages to a peak, age-appropriate design has emerged and become a field of great interest. The kitchen, as a frequently used space, must consider the physiological and psychological needs of the elderly in its design, with …
AI Psychometrics: Evaluating the Psychological Reasoning of Large Language Models with Psychometric Validities Open
The immense number of parameters and deep neural networks make large language models (LLMs) rival the complexity of human brains, which also makes them opaque "black box" systems that are challenging to evaluate and interpret. AI Psychomet…
Generalized coherent wave control at dynamic interfaces Open
Coherent wave control is of key importance across a broad range of fields such as electromagnetics, photonics, and acoustics. It enables us to amplify or suppress the outgoing waves via engineering amplitudes and phases of multiple inciden…
Biosynthesis of trialkyl-substituted aromatic polyketide NFAT-133 involves unusual P450 monooxygenase-mediating aromatization and a putative metallo-beta-lactamase fold hydrolase Open
The bacterial trialkyl-substituted aromatic polyketides are structurally featured with the unusual aromatic core in the middle of polyketide chain such as TM-123 (1), veramycin A (2), NFAT-133 (3) and benwamycin I (4), which were discovere…
Data from Cytokine-like Molecule CCDC134 Contributes to CD8<sup>+</sup> T-cell Effector Functions in Cancer Immunotherapy Open
CCDC134 is a poorly characterized secreted protein that may act as an immune cytokine. Here, we show that CCDC134 is differentially expressed on resting and activated immune cells and that it promotes CD8+ T-cell activation, proliferation,…
Supplemental Figure S1 from Cytokine-like Molecule CCDC134 Contributes to CD8<sup>+</sup> T-cell Effector Functions in Cancer Immunotherapy Open
Homo sapiens and Mus musculus CCDC134 are highly similar.
Supplemental Figure S4 from Cytokine-like Molecule CCDC134 Contributes to CD8<sup>+</sup> T-cell Effector Functions in Cancer Immunotherapy Open
Potent antitumor activity of CCDC134 in vivo.
Supplemental Figure S4 from Cytokine-like Molecule CCDC134 Contributes to CD8<sup>+</sup> T-cell Effector Functions in Cancer Immunotherapy Open
Potent antitumor activity of CCDC134 in vivo.
Supplemental Figure S2 from Cytokine-like Molecule CCDC134 Contributes to CD8<sup>+</sup> T-cell Effector Functions in Cancer Immunotherapy Open
CCDC134 has no apparent effect on activation, effector function and proliferation of mouse CD4+ T cells.
Supplemental Figure S2 from Cytokine-like Molecule CCDC134 Contributes to CD8<sup>+</sup> T-cell Effector Functions in Cancer Immunotherapy Open
CCDC134 has no apparent effect on activation, effector function and proliferation of mouse CD4+ T cells.
Supplemental Figure S1 from Cytokine-like Molecule CCDC134 Contributes to CD8<sup>+</sup> T-cell Effector Functions in Cancer Immunotherapy Open
Homo sapiens and Mus musculus CCDC134 are highly similar.
Supplemental Figure S3 from Cytokine-like Molecule CCDC134 Contributes to CD8<sup>+</sup> T-cell Effector Functions in Cancer Immunotherapy Open
Identification of established CCDC134 transgenic mice.
Supplemental Figure S3 from Cytokine-like Molecule CCDC134 Contributes to CD8<sup>+</sup> T-cell Effector Functions in Cancer Immunotherapy Open
Identification of established CCDC134 transgenic mice.
Supplemental data from Cytokine-like Molecule CCDC134 Contributes to CD8<sup>+</sup> T-cell Effector Functions in Cancer Immunotherapy Open
Supplemental materials and methods and legends for all supplemental figures.
Supplemental Figure S5 from Cytokine-like Molecule CCDC134 Contributes to CD8<sup>+</sup> T-cell Effector Functions in Cancer Immunotherapy Open
Involvement of CD4+ T cells in the induction of antitumor activity by CCDC134.
Supplemental Figure S5 from Cytokine-like Molecule CCDC134 Contributes to CD8<sup>+</sup> T-cell Effector Functions in Cancer Immunotherapy Open
Involvement of CD4+ T cells in the induction of antitumor activity by CCDC134.
Data from Cytokine-like Molecule CCDC134 Contributes to CD8<sup>+</sup> T-cell Effector Functions in Cancer Immunotherapy Open
CCDC134 is a poorly characterized secreted protein that may act as an immune cytokine. Here, we show that CCDC134 is differentially expressed on resting and activated immune cells and that it promotes CD8+ T-cell activation, proliferation,…
Supplemental data from Cytokine-like Molecule CCDC134 Contributes to CD8<sup>+</sup> T-cell Effector Functions in Cancer Immunotherapy Open
Supplemental materials and methods and legends for all supplemental figures.
Sparse and Integrative Principal Component Analysis for Multiview Data Open
We consider dimension reduction of multiview data, which are emerging in scientific studies. Formulating multiview data as multi-variate data with block structures corresponding to the different views, or views of data, we estimate top eig…
How do RNA binding proteins trigger liquid-liquid phase separation in human health and diseases? Open
RNA-binding proteins (RBPs) lie at the center of post-transcriptional regulation and protein synthesis, adding complexity to RNA life cycle. RBPs also participate in the formation of membrane-less organelles (MLOs) via undergoing liquid-li…
View article: PyPose: A Library for Robot Learning with Physics-based Optimization
PyPose: A Library for Robot Learning with Physics-based Optimization Open
Deep learning has had remarkable success in robotic perception, but its data-centric nature suffers when it comes to generalizing to ever-changing environments. By contrast, physics-based optimization generalizes better, but it does not pe…