Xin Li
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View article: Systemic immune-inflammation index: a key biomarker guiding personalized adjuvant chemotherapy in intrahepatic cholangiocarcinoma
Systemic immune-inflammation index: a key biomarker guiding personalized adjuvant chemotherapy in intrahepatic cholangiocarcinoma Open
Background Intrahepatic cholangiocarcinoma (ICC) is a highly aggressive primary liver malignancy, with poor long-term outcomes even after curative-intent resection. Postoperative adjuvant chemotherapy (pAC) is increasingly used, but its be…
View article: Mapping of a Major Locus for Resistance to Yellow Rust in Wheat
Mapping of a Major Locus for Resistance to Yellow Rust in Wheat Open
Yellow rust (YR), caused by Puccinia striiformis f. sp. tritici (Pst), is a global disease infecting wheat that seriously affects the yield and the quality of grains. Wheat breeding line C855 is immune to the mixed Pst isolates CYR32 + CYR…
View article: <scp> <i>Euphorbia pekinensis</i> </scp> glycosphingolipids disrupt gut motility and fluid balance via TRPA1 activation in enterochromaffin cells
<span> <i>Euphorbia pekinensis</i> </span> glycosphingolipids disrupt gut motility and fluid balance via TRPA1 activation in enterochromaffin cells Open
Background and purpose Euphorbia pekinensis (EP) is known to cause significant intestinal toxicity, primarily manifesting as severe diarrhoea, yet the precise molecular mechanisms and the active components responsible have remained elusive…
View article: Large ore detection in blasting piles using LODM
Large ore detection in blasting piles using LODM Open
After blasting in an open-pit mine, it has great guiding significance for the subsequent secondary crushing, shovel loading, transportation and other processes to obtain the large ore fragmentations of the blasting pile, which also plays a…
View article: Research hotspots in the treatment of neonatal hyperbilirubinemia: a bibliometric study and visualization analysis via CiteSpace
Research hotspots in the treatment of neonatal hyperbilirubinemia: a bibliometric study and visualization analysis via CiteSpace Open
Objective To analyze the research status, hotspots, and trends in hyperbilirubinemia treatment, providing reference for future research and clinical practice. Methods Relevant studies on hyperbilirubinemia treatment from January 1, 2000, t…
View article: Sentinel-1 vegetation optical depth retrievals over the international soil moisture network
Sentinel-1 vegetation optical depth retrievals over the international soil moisture network Open
Vegetation optical depth (VOD), a microwave-based vegetation index for vegetation water content and biomass, is primarily retrieved from low spatial resolution passive microwave data, and few studies have focused on VOD retrievals from act…
View article: Breaking hypoxic barrier: Oxygen-supplied nanomaterials for enhanced T cell-mediated tumor immunotherapy
Breaking hypoxic barrier: Oxygen-supplied nanomaterials for enhanced T cell-mediated tumor immunotherapy Open
Hypoxia in the tumor microenvironment (TME) is a critical barrier to effective cancer immunotherapy, as it suppresses T cell infiltration and response while fostering immune evasion. Oxygen-supplied nanomaterials (OSNs) have recently emerg…
View article: Identification of CD159A as a prognostic and immune biomarker in kidney renal clear cell carcinoma
Identification of CD159A as a prognostic and immune biomarker in kidney renal clear cell carcinoma Open
Kidney renal clear cell carcinoma (KIRC) is a highly aggressive malignant tumor, and its occurrence and progression are influenced by tumor microenvironment (TME). CD159A, a natural killer (NK) cell inhibitory receptor, has emerged as a cr…
View article: Novel BCR-Targeting Fusion Proteins for Antigen-Specific Depletion of Alloreactive B Cells in Antibody-Mediated Rejection
Novel BCR-Targeting Fusion Proteins for Antigen-Specific Depletion of Alloreactive B Cells in Antibody-Mediated Rejection Open
Donor-specific anti-HLA antibodies (DSAs) bind to donor vascular endothelial cells and mediate allograft rejection (AMR), but a clinical challenge for which targeted therapeutic options remain limited. We used a multiplexed single-antigen …
View article: Spatial patterns and determinants of inter-provincial migration across age groups in China
Spatial patterns and determinants of inter-provincial migration across age groups in China Open
Individuals in different life stages have different intentions and reasons for migration, which leads to differences in the spatial patterns of migration across age groups. This paper aims to reveal the different patterns of inter-provinci…
View article: The regulatory effects of maize saving irrigation in arid region
The regulatory effects of maize saving irrigation in arid region Open
The increased drought stress caused by worldwide climate-change-driven aridification has exacerbated water scarcity in agricultural production, posing a significant challenge to agricultural sustainability. This study was conducted at Huax…
View article: Dynamic behavior and cumulative deformation analysis of ferronickel slag-clay mixtures under cyclic loading
Dynamic behavior and cumulative deformation analysis of ferronickel slag-clay mixtures under cyclic loading Open
Ferronickel slag, an industrial byproduct, shows potential as road subgrade filler after modification. However, its permanent deformation accumulation under cyclic traffic loads may cause rutting and cracking, compromising long-term perfor…
View article: Effect of microwave combined with steam pretreatment on the flavor and quality of Tibetan chicken soup
Effect of microwave combined with steam pretreatment on the flavor and quality of Tibetan chicken soup Open
Conventional processing relies on time-consuming and intricate stewing methods, which hinder industrial-scale production of chicken soup. To address this limitation, this study investigated the effect of pretreatment cycle number on the qu…
View article: Holocene Climate Shifts Driving Black Soil Formation in NE China: Palynology and AMS14C Dating Insights
Holocene Climate Shifts Driving Black Soil Formation in NE China: Palynology and AMS14C Dating Insights Open
In this study, 14 palynological samples and nine AMS 14C dating samples were collected from two representative black soil profiles in the Xingkai Lake Plain to examine climate changes and their impacts on environmental evolution since the …
View article: Urban expansion in China from a land price equilibrium perspective: regulatory theory and empirical study
Urban expansion in China from a land price equilibrium perspective: regulatory theory and empirical study Open
Rapid urban expansion has brought growing pressure and challenges to the sustainability of urban development. Therefore, exploring urban expansion’s regulation and spatial optimization is essential, particularly in China. This study first …
View article: Time-series metatranscriptomics reveals differential salinity effects on the methanogenic food web in paddy soil
Time-series metatranscriptomics reveals differential salinity effects on the methanogenic food web in paddy soil Open
Saltwater intrusion and sea level rise (SWISLR) threaten coastal agroecosystems, yet their impact on the methanogenic food web in rice paddies remains virtually unknown. Using “double-RNA” metatranscriptomics (rRNA, mRNA), we investigated …
View article: Leaching Characteristics of Exogenous Cl− in Rain-Fed Potato Fields and Residual Estimation Model Validation
Leaching Characteristics of Exogenous Cl− in Rain-Fed Potato Fields and Residual Estimation Model Validation Open
Potato (Solanum tuberosum L.) is a chlorine-sensitive crop. When soil Cl− concentrations exceed optimal thresholds, the yield and quality of potatoes are limited. Consequently, chloride-containing fertilizers are rarely used in actual agri…
View article: tRNA-derived small RNA 3’ tRF-Ala CGC obstructs NK cytotoxicity via cleavage of membrane protein MICA in colorectal cancer
tRNA-derived small RNA 3’ tRF-Ala CGC obstructs NK cytotoxicity via cleavage of membrane protein MICA in colorectal cancer Open
Background Immune escape remains a major challenge in cancer immunotherapy. Transfer RNA (tRNA)-derived small RNA (tsRNA) represents a novel class of non-coding RNAs generated from tRNA cleavage, regulating gene expression at transcription…
View article: Insect-Foundation: A Foundation Model and Large Multimodal Dataset for Vision-Language Insect Understanding
Insect-Foundation: A Foundation Model and Large Multimodal Dataset for Vision-Language Insect Understanding Open
Multimodal conversational generative AI has shown impressive capabilities in various vision and language understanding through learning massive text-image data. However, current conversational models still lack knowledge about visual insec…
View article: Parental Marital Quality and School Bullying Victimization: A Moderated Mediation Model of Parent–Child Attachment and Child Gender
Parental Marital Quality and School Bullying Victimization: A Moderated Mediation Model of Parent–Child Attachment and Child Gender Open
Background/Objectives: School bullying is a significant issue that negatively impacts children’s well-being, emphasizing the need to identify family-related factors contributing to bullying victimization. This study explored the potential …
View article: Epigenetic Regulation of GFRA1 by Extracellular Vesicle lncRNA SOX9‐AS1 Facilitates Breast Cancer Metastasis
Epigenetic Regulation of GFRA1 by Extracellular Vesicle lncRNA SOX9‐AS1 Facilitates Breast Cancer Metastasis Open
Breast cancer (BRCA) metastasis remains a critical clinical challenge, with extracellular vesicles (EVs) playing a significant role in intercellular communication during tumor progression. This study investigates the role of EV‐enriched lo…
View article: Macrophage-Secreted U2AF1 Orchestrates Coronary Artery Angiogenesis to Facilitate Myocardial Infarction Repair Through the Regulation of Yap1 Variable Splicing
Macrophage-Secreted U2AF1 Orchestrates Coronary Artery Angiogenesis to Facilitate Myocardial Infarction Repair Through the Regulation of Yap1 Variable Splicing Open
Myocardial infarction (MI) is characterized by focal necrosis resulting from prolonged myocardial ischemia due to coronary artery obstruction. Vascular reconstruction following MI is crucial for improving cardiac function and preventing re…
View article: Physiological responses of cotton roots and soil microbial adaptation to drought hardening
Physiological responses of cotton roots and soil microbial adaptation to drought hardening Open
Background: As global climate changing significantly exacerbated the frequency and intensity of drought stress, posing severe challenges to the sustainable development of agriculture in arid regions. Aims: This investigation employed integ…
View article: NTIRE 2025 XGC Quality Assessment Challenge: Methods and Results
NTIRE 2025 XGC Quality Assessment Challenge: Methods and Results Open
This paper reports on the NTIRE 2025 XGC Quality Assessment Challenge, which will be held in conjunction with the New Trends in Image Restoration and Enhancement Workshop (NTIRE) at CVPR 2025. This challenge is to address a major challenge…
View article: Surging Processes and Mechanisms at Small Glaciers in the Qilian Mountains, Northwestern China, Revealed by Long‐Term, Temporally Dense Remote Sensing Observations
Surging Processes and Mechanisms at Small Glaciers in the Qilian Mountains, Northwestern China, Revealed by Long‐Term, Temporally Dense Remote Sensing Observations Open
A glacier surge, an exceptional phenomenon of mass redistribution, is one of the least understood dynamic processes in cryospheric science. Long‐term detailed changes in glacier elevation and flow velocity are crucial for assessing surge d…
View article: Research hotspots of irisin in the nervous system: a bibliometric study and visualization analysis via CiteSpace
Research hotspots of irisin in the nervous system: a bibliometric study and visualization analysis via CiteSpace Open
Objective To visually analyze the current status, hotspots, and frontiers of irisin in the nervous system and to provide a reference for future clinical research. Methods Web of Science Core Collection (WoSCC), PubMed, Embase, and Cochrane…
View article: Urban Spatial Blessing: Effect of Land Use Intensity on Human Development Index
Urban Spatial Blessing: Effect of Land Use Intensity on Human Development Index Open
Urban land use is characterized by pronounced externalities. In most developing countries, economic welfare considerations drive the changes in land use intensity, leading to the spatial reallocation of resources and thereby affecting the …
View article: Prediction of the Impact of the Central Yunnan Water Diversion Project on Reducing Water Shortage Risk and Its Inequality in Receiving Areas Using an Integrated Framework
Prediction of the Impact of the Central Yunnan Water Diversion Project on Reducing Water Shortage Risk and Its Inequality in Receiving Areas Using an Integrated Framework Open
Water resources are essential for human survival and socio-economic development, yet ensuring a reliable supply to meet domestic, industrial, and ecological demands remains a critical challenge in water-scarce regions. In response to sever…
View article: Efficient Testing Light Path for Aspherical Surfaces Based on Secondary Imaging
Efficient Testing Light Path for Aspherical Surfaces Based on Secondary Imaging Open
At present, off-axis three-mirror optical systems mostly adopt aspherical mirrors with small apertures and small F/# to meet the development requirements of remote sensing payloads towards high precision, small volume, and lightweight desi…
View article: A backbone-based inverse kinematics and head traction path-following algorithm for soft manipulators
A backbone-based inverse kinematics and head traction path-following algorithm for soft manipulators Open
This paper introduces an inverse kinematics solution and a path-following method for a tendon-driven soft manipulator. The inverse kinematics problem is addressed using a modified backbone method, where the spatial backbone is defined by t…