Xin Luo
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View article: Biomarker-driven mechanisms and therapeutic targets for prostate diseases through mendelian randomization and molecular docking
Biomarker-driven mechanisms and therapeutic targets for prostate diseases through mendelian randomization and molecular docking Open
This study provides genetic evidence linking biomarkers to prostate diseases and identifies novel druggable targets and repurposing opportunities, offering mechanistic insights and prospects for precision therapy.
View article: Characterization and phylogenetic analysis of a novel filamentous polymycovirus GbPmV1
Characterization and phylogenetic analysis of a novel filamentous polymycovirus GbPmV1 Open
Impact statement Mycoviruses are common in fungi and can change their host's functions. Here, we identify a novel dsRNA mycovirus GbPmV1 from the fungus Gongronella butleri . The genome of GbPmV1 exceeds 10,000 nucleotides and comprises si…
View article: Synchronous Stability Analysis and Enhanced Control of Power Systems with Grid-Following and Grid-Forming Converters Considering Converter Distribution
Synchronous Stability Analysis and Enhanced Control of Power Systems with Grid-Following and Grid-Forming Converters Considering Converter Distribution Open
Under the backdrop of low-carbon energy transition, the increasing integration of grid-following (GFL) and grid-forming (GFM) converters into power systems is profoundly altering transient synchronous stability. A critical challenge lies i…
View article: Microporous structures on mineralized collagen mediate bone restoration by promoting nucleolin secretion to induce macrophage M2 polarization
Microporous structures on mineralized collagen mediate bone restoration by promoting nucleolin secretion to induce macrophage M2 polarization Open
Bone defects rehabilitation is one of the difficulties in oral clinical practice. Implanted biomaterials have pivotal effects on the regeneration in critical bone defects, but the immunologic reactions arising from their entrying into the …
View article: Impact of gas in different occurrence states on P-wave amplitude in coal
Impact of gas in different occurrence states on P-wave amplitude in coal Open
View article: The role of forestland size on rural household’s forest management efficiency
The role of forestland size on rural household’s forest management efficiency Open
View article: Evaluation of safety and efficacy of Tirofiban injection for treating acute ischemic stroke beyond standard time window
Evaluation of safety and efficacy of Tirofiban injection for treating acute ischemic stroke beyond standard time window Open
To evaluate the safety and efficacy of tirofiban in the treatment of acute ischemic stroke (AIS). Clinical data of 152 AIS patients with small vessel occlusion admitted in 2023 were retrospectively analyzed. These patients did not receive …
View article: A novel lightweight model integrating convolutional neural network and self-attention mechanism for corn seeds quality image recognition
A novel lightweight model integrating convolutional neural network and self-attention mechanism for corn seeds quality image recognition Open
View article: Identifying novel therapeutic targets of natural compounds in traditional Chinese medicine herbs with hypergraph representation learning
Identifying novel therapeutic targets of natural compounds in traditional Chinese medicine herbs with hypergraph representation learning Open
Traditional Chinese medicine (TCM), with its roots in centuries of clinical practice, has established itself as an effective therapeutic system that involves a diverse range of herbal plants. Despite its proven efficacy, the intricate rela…
View article: Pharmacokinetics, Safety, and Tolerability of Single‐Dose Dazukibart in Healthy Adults in China and Japan: Results From 2 Randomized, Double‐Blind, Phase 1 Studies
Pharmacokinetics, Safety, and Tolerability of Single‐Dose Dazukibart in Healthy Adults in China and Japan: Results From 2 Randomized, Double‐Blind, Phase 1 Studies Open
Dazukibart is a humanized monoclonal antibody selectively targeting interferon‐β. The pharmacokinetics (PK), safety, tolerability, and immunogenicity of dazukibart were evaluated in 2 double‐blind, randomized, placebo‐controlled, single‐do…
View article: Study on the leaf epidermis micromorphology of six medicinal plant species in Smilax from Henan Province
Study on the leaf epidermis micromorphology of six medicinal plant species in Smilax from Henan Province Open
View article: Exploiting Diffusion Prior for Real-World Image Dehazing with Unpaired Training
Exploiting Diffusion Prior for Real-World Image Dehazing with Unpaired Training Open
Unpaired training has been verified as one of the most effective paradigms for real scene dehazing by learning from unpaired real-world hazy and clear images. Although numerous studies have been proposed, current methods demonstrate limite…
View article: Body mass index and post-thyroidectomy hypocalcemia: a protective effect of overweight through non-surgical mechanisms—a propensity score-matched study
Body mass index and post-thyroidectomy hypocalcemia: a protective effect of overweight through non-surgical mechanisms—a propensity score-matched study Open
View article: Efficacy and safety of etrasimod in alopecia areata: A multicentre, randomized, double‐blind, placebo‐controlled, Phase 2 study
Efficacy and safety of etrasimod in alopecia areata: A multicentre, randomized, double‐blind, placebo‐controlled, Phase 2 study Open
Background Etrasimod, an oral, selective sphingosine 1‐phosphate 1, 4 and 5 receptor modulator approved for the treatment of ulcerative colitis, has been studied in immune‐mediated inflammatory diseases, including alopecia areata (AA). Obj…
View article: Exploiting Diffusion Prior for Real-World Image Dehazing with Unpaired Training
Exploiting Diffusion Prior for Real-World Image Dehazing with Unpaired Training Open
Unpaired training has been verified as one of the most effective paradigms for real scene dehazing by learning from unpaired real-world hazy and clear images. Although numerous studies have been proposed, current methods demonstrate limite…
View article: Searching for an Accurate Robot Calibration via Improved Levenberg–Marquardt and Radial Basis Function System
Searching for an Accurate Robot Calibration via Improved Levenberg–Marquardt and Radial Basis Function System Open
Robots are frequently utilized in manufacturing, aviation, and other industries, which enhance industrial production efficiency and quality. Specifically, robots perform high‐precision tasks like welding, assembly and material handling, wh…
View article: Basic-Leucine-Zipper Transcription Factors Regulate Selective Molecular Phenotypes in Regulatory T Cells During IL-2-Induced Activation
Basic-Leucine-Zipper Transcription Factors Regulate Selective Molecular Phenotypes in Regulatory T Cells During IL-2-Induced Activation Open
Summary Regulatory T (Treg) cells have long been recognized as modulators of immunological tolerance and homeostasis. Previously, we used scRNA-seq to reveal significant Treg heterogeneity in response to IL-2-induced activation. Herein, we…
View article: Attention-Mechanism-Based Neural Latent-Factorization-of-Tensors Model
Attention-Mechanism-Based Neural Latent-Factorization-of-Tensors Model Open
High-Dimensional and Incomplete (HDI) tensors contain a wealth of knowledge and patterns, which are typically utilized to characterize complex relationships between entities in a variety of industrial applications. Currently, the neural ne…
View article: Learning-based polarization retrieval from intensity speckle of dense scattering media
Learning-based polarization retrieval from intensity speckle of dense scattering media Open
Polarization information is vital for recovering the fine details and structure of the object in complex scattering environments. However, existing methods for acquiring polarization information typically rely on specialized imaging system…
View article: Long‐term safety and efficacy of ritlecitinib in adults and adolescents with alopecia areata and at least 25% scalp hair loss: Results from the <scp>ALLEGRO</scp>‐<scp>LT</scp> phase 3, open‐label study
Long‐term safety and efficacy of ritlecitinib in adults and adolescents with alopecia areata and at least 25% scalp hair loss: Results from the <span>ALLEGRO</span>‐<span>LT</span> phase 3, open‐label study Open
Background ALLEGRO‐LT is an ongoing, long‐term, open‐label, multicentre, phase 3 study of ritlecitinib in adults and adolescents with alopecia areata (AA). Objectives To evaluate ritlecitinib safety and efficacy through Month 24 in patient…
View article: Hybrid‐data‐driven bridge weigh‐in‐motion technology using a two‐level sequential artificial neural network
Hybrid‐data‐driven bridge weigh‐in‐motion technology using a two‐level sequential artificial neural network Open
For existing bridge weigh‐in‐motion technologies, the main challenge in accurate weight estimation is to overcome the difficulty of identifying the closely spaced axles. To do so, many field test data are generally required for each bridge…
View article: From “Ugly Duckling” to “Reform”: Explaining the Marginalisation and Resurgence of Britain’s Right-Wing Populist Parties
From “Ugly Duckling” to “Reform”: Explaining the Marginalisation and Resurgence of Britain’s Right-Wing Populist Parties Open
View article: Revolutionizing optical imaging: computational imaging via deep learning
Revolutionizing optical imaging: computational imaging via deep learning Open
View article: Study on Multi-scale Correlation Mechanism of Fatigue Characteristics of Warm Mix Recycled Asphalt-Mortar-Mixture
Study on Multi-scale Correlation Mechanism of Fatigue Characteristics of Warm Mix Recycled Asphalt-Mortar-Mixture Open
View article: Co-infection with Pseudomonas aeruginosa and Leishmania donovani impairs antiparasitic immunity via NOD-like receptor pathway
Co-infection with Pseudomonas aeruginosa and Leishmania donovani impairs antiparasitic immunity via NOD-like receptor pathway Open
View article: Progressively Exploring and Exploiting Cost-Free Data to Break Fine-Grained Classification Barriers
Progressively Exploring and Exploiting Cost-Free Data to Break Fine-Grained Classification Barriers Open
Current fine-grained classification research primarily focuses on fine-grained feature learning. However, in real-world scenarios, fine-grained data annotation is challenging, and the features and semantics are highly diverse and frequentl…
View article: Exosomes containing circSCP2 in colorectal cancer promote metastasis via sponging miR-92a-1-5p and interacting with PTBP1 to stabilize IGF2BP1
Exosomes containing circSCP2 in colorectal cancer promote metastasis via sponging miR-92a-1-5p and interacting with PTBP1 to stabilize IGF2BP1 Open
View article: FEMINISM OR MISOGYNY? EXPLORING THE RELATIONSHIP BETWEEN BOY’S LOVE DRAMA EXPOSURE, THE FEMALE GAZE, FANDOM ENGAGEMENT, AND GENDER IDEOLOGY
FEMINISM OR MISOGYNY? EXPLORING THE RELATIONSHIP BETWEEN BOY’S LOVE DRAMA EXPOSURE, THE FEMALE GAZE, FANDOM ENGAGEMENT, AND GENDER IDEOLOGY Open
The prevalence of Boyâs Love (BL) drama in recent years has challenged Chinaâs everlasting state-manipulated heteronormative ideology and patriarchy hegemony. However, it remains unknown whether exposure to BL drama makes female audien…
View article: Current status and prospects of nucleic acid mass spectrometry in clinical pharmacogenomics
Current status and prospects of nucleic acid mass spectrometry in clinical pharmacogenomics Open
View article: Study on the effect of chlorogenic acid on the antimicrobial effect, physical properties and model accuracy of alginate impression materials
Study on the effect of chlorogenic acid on the antimicrobial effect, physical properties and model accuracy of alginate impression materials Open
Background Dental impressions are essential for accurately capturing the detailed anatomy of teeth and surrounding oral structures. However, these impressions often become contaminated with saliva and blood, making proper disinfection nece…