Xiangnan Chen
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View article: Overcoming Challenges in AAV Plasmid Preparation: Advanced Solutions for Superior ITR Integrity and High-Yield Production 9427
Overcoming Challenges in AAV Plasmid Preparation: Advanced Solutions for Superior ITR Integrity and High-Yield Production 9427 Open
Description AAV-based gene therapies are transforming treatments for genetic disorders, cancer, and rare diseases. However, preparing high-quality AAV plasmids is challenging, particularly in maintaining ITR integrity due to its repetitive…
View article: New RPC gas mixtures for sustainable operation in the CMS experiment
New RPC gas mixtures for sustainable operation in the CMS experiment Open
The current operation of the Resistive Plate Chamber (RPC) system within the CMS experiment involves approximately 95% tetrafluoroethane (C2H2F4, TFE). However, in response to climate change concerns, the European Union has instituted a ba…
View article: The Influence of Family Structure and Gender on Adolescent Development: A Comparative Study of Only Children and Non-Only Children
The Influence of Family Structure and Gender on Adolescent Development: A Comparative Study of Only Children and Non-Only Children Open
Adolescence is a critical developmental stage characterized by significant physiological, psychological changes. Adolescents' mental health is closely linked to their personal development, family well-being, and societal harmony. In the pa…
View article: Synergistic Inhibition of Nav1.7 and <scp>NCX</scp>1: A Novel Strategy for Treating Cancer‐Induced Bone Pain by Modulating Pain Sensitization and Neuronal Inflammation
Synergistic Inhibition of Nav1.7 and <span>NCX</span>1: A Novel Strategy for Treating Cancer‐Induced Bone Pain by Modulating Pain Sensitization and Neuronal Inflammation Open
Aims Cancer‐induced bone pain (CIBP) is a chronic and refractory pain condition characterized by neuronal hyperexcitability, calcium dysregulation, and neuroinflammation. Voltage‐gated sodium channels (VGSCs) and sodium/calcium exchangers …
View article: Toxicokinetics and responses of multiple biomarkers of sediment-associated fluoroquinolones in the freshwater benthic gastropod Bellamya aeruginosa
Toxicokinetics and responses of multiple biomarkers of sediment-associated fluoroquinolones in the freshwater benthic gastropod Bellamya aeruginosa Open
Fluoroquinolones (FQs) have the propensity to accumulate in sediments once introduction into aquatic environments, thereby posing potential threats to benthic organisms, yet the ecotoxicity of sediment-associated FQs remains unclear. In th…
View article: CMS RPC L1 Trigger clustering at CMSSW
CMS RPC L1 Trigger clustering at CMSSW Open
International audience
View article: Novel terahertz optical switch based on PIT phenomenon and Lorentz theory
Novel terahertz optical switch based on PIT phenomenon and Lorentz theory Open
We propose and demonstrate a structure consisting of graphene rings and square rings that enables broadband and tunable plasmon-induced transparency (PIT) effects. Through coupled Lorentz model analysis, we attribute the transmission windo…
View article: The Benefits of Re-employment Among the Elderly: Perspectives on the Silver Economy and Re-employment Willingness
The Benefits of Re-employment Among the Elderly: Perspectives on the Silver Economy and Re-employment Willingness Open
As China's population ages, the challenges this demographic shift presents are becoming increasingly clear. The re-employment of older adults, however, offers new opportunities for economic development and social welfare. This study examin…
View article: Sex differences in <scp>PD</scp>‐<scp>L1</scp>‐induced analgesia in paclitaxel‐induced peripheral neuropathy mice depend on <scp>TRPV1</scp>‐based inhibition of <scp>CGRP</scp>
Sex differences in <span>PD</span>‐<span>L1</span>‐induced analgesia in paclitaxel‐induced peripheral neuropathy mice depend on <span>TRPV1</span>‐based inhibition of <span>CGRP</span> Open
Aims Paclitaxel (PTX) is extensively utilized in the management of diverse solid tumors, frequently resulting in paclitaxel‐induced peripheral neuropathy (PIPN). The present study aimed to investigate sex differences in the behavioral mani…
View article: The Janus Structure of Graphene Oxide and Its Large-Size Conductive Film Strip Pattern
The Janus Structure of Graphene Oxide and Its Large-Size Conductive Film Strip Pattern Open
In this paper, the oxidation–exfoliation process of graphite is studied experimentally by the mixed-solvent method, the oxidation–exfoliation process of graphite is simulated theoretically, and it is found that Graphene Oxide (GO) is a Jan…
View article: Negative Sampling with Adaptive Denoising Mixup for Knowledge Graph Embedding
Negative Sampling with Adaptive Denoising Mixup for Knowledge Graph Embedding Open
Knowledge graph embedding (KGE) aims to map entities and relations of a knowledge graph (KG) into a low-dimensional and dense vector space via contrasting the positive and negative triples. In the training process of KGEs, negative samplin…
View article: Neural axiom network for knowledge graph reasoning
Neural axiom network for knowledge graph reasoning Open
Knowledge graph reasoning (KGR) aims to infer new knowledge or detect noises, which is essential for improving the quality of knowledge graphs. Recently, various KGR techniques, such as symbolic- and embedding-based methods, have been prop…
View article: Global Structure Knowledge-Guided Relation Extraction Method for Visually-Rich Document
Global Structure Knowledge-Guided Relation Extraction Method for Visually-Rich Document Open
Visual Relation Extraction (VRE) is a powerful means of discovering relationships between entities within visually-rich documents. Existing methods often focus on manipulating entity features to find pairwise relations, yet neglect the mor…
View article: Recent Advances for Electrode Modifications in Flow Batteries: Properties, Mechanisms, and Outlooks
Recent Advances for Electrode Modifications in Flow Batteries: Properties, Mechanisms, and Outlooks Open
Flow batteries (FBs) have been demonstrated in several large‐scale energy storage projects, and are considered to be the preferred technique for large‐scale long‐term energy storage in terms of their high safety, environmental friendliness…
View article: Global Structure Knowledge-Guided Relation Extraction Method for Visually-Rich Document
Global Structure Knowledge-Guided Relation Extraction Method for Visually-Rich Document Open
Visual Relation Extraction (VRE) is a powerful means of discovering relationships between entities within visually-rich documents. Existing methods often focus on manipulating entity features to find pairwise relations, yet neglect the mor…
View article: Analysis on Management Policies on Water Quantity Conflict in Transboundary Rivers Embedded with Virtual Water—Using Ili River as the Case
Analysis on Management Policies on Water Quantity Conflict in Transboundary Rivers Embedded with Virtual Water—Using Ili River as the Case Open
Current studies neglect how virtual water transfer (VWT) between countries within a drainage basin affects water stress and then yields an invisible effect on the water quantity conflict in transboundary rivers, which would further make ma…
View article: Invisible Effect of Virtual Water Transfer on Water Quantity Conflict in Transboundary Rivers—Taking Ili River as a Case
Invisible Effect of Virtual Water Transfer on Water Quantity Conflict in Transboundary Rivers—Taking Ili River as a Case Open
Water stress in countries within a drainage basin exacerbates the water quantity conflict in transboundary rivers. However, few studies considered the invisible effect of virtual water transfer on water quantity conflict by intensifying wa…
View article: Design of Flexible Film-Forming Polydopamine/Polypyrrole/Nanodiamond Hierarchical Structure for Broadband Microwave Absorption
Design of Flexible Film-Forming Polydopamine/Polypyrrole/Nanodiamond Hierarchical Structure for Broadband Microwave Absorption Open
Microwave-absorbing materials are widely used in numerous fields, including the military, daily protection, etc. Currently, in addition to being lightweight and highly efficient, good film-forming processing characteristics and environment…
View article: Meta-Learning Based Knowledge Extrapolation for Knowledge Graphs in the Federated Setting
Meta-Learning Based Knowledge Extrapolation for Knowledge Graphs in the Federated Setting Open
We study the knowledge extrapolation problem to embed new components (i.e., entities and relations) that come with emerging knowledge graphs (KGs) in the federated setting. In this problem, a model trained on an existing KG needs to embed …
View article: NeuralKG: An Open Source Library for Diverse Representation Learning of Knowledge Graphs
NeuralKG: An Open Source Library for Diverse Representation Learning of Knowledge Graphs Open
NeuralKG is an open-source Python-based library for diverse representation learning of knowledge graphs. It implements three different series of Knowledge Graph Embedding (KGE) methods, including conventional KGEs, GNN-based KGEs, and Rule…
View article: Systematic review and meta-analysis of the prognostic value of Narcotrend monitoring of different depths of anesthesia and different Bispectral Index (BIS) values for cognitive dysfunction after tumor surgery in elderly patients
Systematic review and meta-analysis of the prognostic value of Narcotrend monitoring of different depths of anesthesia and different Bispectral Index (BIS) values for cognitive dysfunction after tumor surgery in elderly patients Open
BACKGROUND: To study the effect of Narcotrend monitoring on the incidence of early postoperative cognitive dysfunction (POCD) under different Bispectral Index (BIS) conditions and the effect of different depths of anesthesia on the inciden…
View article: Characterization and tribology performance of polyaniline-coated nanodiamond lubricant additives
Characterization and tribology performance of polyaniline-coated nanodiamond lubricant additives Open
The polyaniline (PANi)-coated nanodiamond (ND) composites were fabricated by the in situ polymerization process and dispersed in base oil as nanolubricant additives by ultrasonic-assisted dispersion. The morphology and microstructures of t…
View article: ZJUKLAB at SemEval-2021 Task 4: Negative Augmentation with Language Model for Reading Comprehension of Abstract Meaning
ZJUKLAB at SemEval-2021 Task 4: Negative Augmentation with Language Model for Reading Comprehension of Abstract Meaning Open
This paper presents our systems for the three Subtasks of SemEval Task4: Reading Comprehension of Abstract Meaning (ReCAM). We explain the algorithms used to learn our models and the process of tuning the algorithms and selecting the best …