Xiaoyan Pang
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View article: The Landscape of Anti-HBV Activity in Essential Oils: A Machine Learning-Based Virtual Screening Framework and Anti-HBV Activity of <i>Acorus tatarinowii</i> Schott
The Landscape of Anti-HBV Activity in Essential Oils: A Machine Learning-Based Virtual Screening Framework and Anti-HBV Activity of <i>Acorus tatarinowii</i> Schott Open
View article: Comprehensive analysis of DNA methylation patterns in recurrent miscarriage: imprinted/non-imprinted genes and their regulation across sperm and fetal-maternal tissues
Comprehensive analysis of DNA methylation patterns in recurrent miscarriage: imprinted/non-imprinted genes and their regulation across sperm and fetal-maternal tissues Open
Background Epigenetic regulation, including DNA methylation, is essential for normal embryonic development and maternal-fetal interactions. Recurrent miscarriage (RM), defined as the loss of two or more consecutive pregnancies, poses signi…
View article: Research on Slope Stability Based on Bayesian Gaussian Mixture Model and Random Reduction Method
Research on Slope Stability Based on Bayesian Gaussian Mixture Model and Random Reduction Method Open
Slope stability analysis is conventionally performed using the strength reduction method with the proportional reduction in shear strength parameters. However, during actual slope failure processes, the attenuation characteristics of rock …
View article: Torque Teno Virus Does Not Predict Cytomegalovirus Infection Post-Lung Transplantation
Torque Teno Virus Does Not Predict Cytomegalovirus Infection Post-Lung Transplantation Open
View article: DNA Phosphorothioate Modifications Are Widely Distributed in the Human Microbiome
DNA Phosphorothioate Modifications Are Widely Distributed in the Human Microbiome Open
The DNA phosphorothioate (PT) modification existing in many prokaryotes, including bacterial pathogens and commensals, confers multiple characteristics, including restricting gene transfer, influencing the global transcriptional response, …
View article: Quantification of Human Oral and Fecal Streptococcus parasanguinis by Use of Quantitative Real-Time PCR Targeting the groEL Gene
Quantification of Human Oral and Fecal Streptococcus parasanguinis by Use of Quantitative Real-Time PCR Targeting the groEL Gene Open
Two pairs of species-specific PCR primers targeting the housekeeping groEL gene, Spa146f-Spa525r and Spa93f-Spa525r, were designed to quantify human oral and fecal Streptococcus parasanguinis. Blast analysis against reference…
View article: A More Robust Gut Microbiota in Calorie-Restricted Mice Is Associated with Attenuated Intestinal Injury Caused by the Chemotherapy Drug Cyclophosphamide
A More Robust Gut Microbiota in Calorie-Restricted Mice Is Associated with Attenuated Intestinal Injury Caused by the Chemotherapy Drug Cyclophosphamide Open
Improving the gut microbiota via calorie restriction is beneficial for human health. Our findings showed differential responses between calorie-restricted mice and ad libitum -fed mice. Compared with the ad libitum -fed mice, the calorie-r…
View article: Structural Alteration of Gut Microbiota during the Amelioration of Human Type 2 Diabetes with Hyperlipidemia by Metformin and a Traditional Chinese Herbal Formula: a Multicenter, Randomized, Open Label Clinical Trial
Structural Alteration of Gut Microbiota during the Amelioration of Human Type 2 Diabetes with Hyperlipidemia by Metformin and a Traditional Chinese Herbal Formula: a Multicenter, Randomized, Open Label Clinical Trial Open
Accumulating evidence implicates gut microbiota as promising targets for the treatment of type 2 diabetes mellitus (T2DM). With a randomized clinical trial, we tested the hypothesis that alteration of gut microbiota may be involved in the …
View article: A human stool-derived Bilophila wadsworthia strain caused systemic inflammation in specific-pathogen-free mice
A human stool-derived Bilophila wadsworthia strain caused systemic inflammation in specific-pathogen-free mice Open
View article: Genomic Microdiversity of<i>Bifidobacterium pseudocatenulatum</i>Underlying Differential Strain-Level Responses to Dietary Carbohydrate Intervention
Genomic Microdiversity of<i>Bifidobacterium pseudocatenulatum</i>Underlying Differential Strain-Level Responses to Dietary Carbohydrate Intervention Open
The genomic basis of the response to dietary intervention of human gut beneficial bacteria remains elusive, which hinders precise manipulation of the microbiota for human health. After receiving a dietary intervention enriched with nondige…
View article: Adrenomedullin promotes angiogenesis in epithelial ovarian cancer through upregulating hypoxia-inducible factor-1α and vascular endothelial growth factor
Adrenomedullin promotes angiogenesis in epithelial ovarian cancer through upregulating hypoxia-inducible factor-1α and vascular endothelial growth factor Open
View article: Sex differences in colonization of gut microbiota from a man with short-term vegetarian and inulin-supplemented diet in germ-free mice
Sex differences in colonization of gut microbiota from a man with short-term vegetarian and inulin-supplemented diet in germ-free mice Open
View article: Accelerated dysbiosis of gut microbiota during aggravation of DSS-induced colitis by a butyrate-producing bacterium
Accelerated dysbiosis of gut microbiota during aggravation of DSS-induced colitis by a butyrate-producing bacterium Open
Butyrate-producing bacteria (BPB) are potential probiotic candidates for inflammatory bowel diseases as they are often depleted in the diseased gut microbiota. However, here we found that augmentation of a human-derived butyrate-producing …
View article: Diminution of the gut resistome after a gut microbiota-targeted dietary intervention in obese children
Diminution of the gut resistome after a gut microbiota-targeted dietary intervention in obese children Open
The gut microbiome represents an important reservoir of antibiotic resistance genes (ARGs). Effective methods are urgently needed for managing the gut resistome to fight against the antibiotic resistance threat. In this study, we show that…
View article: CCDC 1449392: Experimental Crystal Structure Determination
CCDC 1449392: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1449391: Experimental Crystal Structure Determination
CCDC 1449391: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Modulation of gut microbiota by berberine and metformin during the treatment of high-fat diet-induced obesity in rats
Modulation of gut microbiota by berberine and metformin during the treatment of high-fat diet-induced obesity in rats Open
Accumulating evidence suggests that the gut microbiota is an important factor in mediating the development of obesity-related metabolic disorders, including type 2 diabetes. Metformin and berberine, two clinically effective drugs for treat…
View article: Differential responses of gut microbiota to the same prebiotic formula in oligotrophic and eutrophic batch fermentation systems
Differential responses of gut microbiota to the same prebiotic formula in oligotrophic and eutrophic batch fermentation systems Open
The same prebiotics have produced inconsistent effects on microbiota when evaluated in different batch fermentation studies. To understand the reasons behind these discrepancies, we compared impact of one prebiotic formula on the same inoc…
View article: Dietary Modulation of Gut Microbiota Contributes to Alleviation of Both Genetic and Simple Obesity in Children
Dietary Modulation of Gut Microbiota Contributes to Alleviation of Both Genetic and Simple Obesity in Children Open
Poorly managed diet and genetic mutations are the two primary driving forces behind the devastating epidemic of obesity-related diseases. Lack of understanding of the molecular chain of causation between the driving forces and the disease …
View article: Adrenomedullin Up-regulates the Expression of Vascular Endothelial Growth Factor in Epithelial Ovarian Carcinoma Cells via JNK/AP-1 Pathway
Adrenomedullin Up-regulates the Expression of Vascular Endothelial Growth Factor in Epithelial Ovarian Carcinoma Cells via JNK/AP-1 Pathway Open
View article: The Bamboo-Eating Giant Panda Harbors a Carnivore-Like Gut Microbiota, with Excessive Seasonal Variations
The Bamboo-Eating Giant Panda Harbors a Carnivore-Like Gut Microbiota, with Excessive Seasonal Variations Open
The giant panda evolved from omnivorous bears. It lives on a bamboo-dominated diet at present, but it still retains a typical carnivorous digestive system and is genetically deficient in cellulose-digesting enzymes. To find out whether thi…
View article: A Filifactor alocis-centered co-occurrence group associates with periodontitis across different oral habitats
A Filifactor alocis-centered co-occurrence group associates with periodontitis across different oral habitats Open