Xing‐Chun Peng
YOU?
Author Swipe
View article: Cepharanthine Loaded TCPP‐MOF Triggers Pyroptosis Through TSPO Inhibition for Hepatocellular Carcinoma Sonodynamic‐Chemotherapy
Cepharanthine Loaded TCPP‐MOF Triggers Pyroptosis Through TSPO Inhibition for Hepatocellular Carcinoma Sonodynamic‐Chemotherapy Open
Pyroptosis is the critical approach for the induction of robust cancer cell death and activation of the immune microenvironment, which often results from mitochondrial damage. Herein, a combination strategy of sonodynamic‐chemotherapy is d…
View article: Dihydroartemisinin-driven selective anti-lung cancer proliferation by binding to EGFR and inhibition of NRAS signaling pathway-induced DNA damage
Dihydroartemisinin-driven selective anti-lung cancer proliferation by binding to EGFR and inhibition of NRAS signaling pathway-induced DNA damage Open
Chemotherapeutic agents can inhibit the proliferation of malignant cells due to their cytotoxicity, which is limited by collateral damage. Dihydroartemisinin (DHA), has a selective anti-cancer effect, whose target and mechanism remain unco…
View article: Indocyanine green-loaded platelet activated by photodynamic and photothermal effects for selective control of wound repair
Indocyanine green-loaded platelet activated by photodynamic and photothermal effects for selective control of wound repair Open
Taken together, the current work identified that platelets could be activated by PDE/PTE and thereby release growth factor, potentiating wound repair in a controlled manner.
View article: Dihydroartemisinin remodels macrophage into an M1 phenotype via ferroptosis-mediated DNA damage
Dihydroartemisinin remodels macrophage into an M1 phenotype via ferroptosis-mediated DNA damage Open
Lung cancer recruits tumor-associated macrophages (TAMs) massively, whose predominantly pro-tumor M2 phenotype leads to immunosuppression. Dihydroartemisinin (DHA) has been proven to remodel TAM into an anti-tumor M1 phenotype at certain c…
View article: Platelets are highly efficient and efficacious carriers for tumor-targeted nano-drug delivery
Platelets are highly efficient and efficacious carriers for tumor-targeted nano-drug delivery Open
The present work aims to prove the concept of tumor-targeted drug delivery mediated by platelets. Doxorubicin (DOX) attached to nanodiamonds (ND-DOX) was investigated as the model payload drug of platelets. In vitro experiments first showe…
View article: Chlorin e6-Induced Photodynamic Effect Polarizes the Macrophage Into an M1 Phenotype Through Oxidative DNA Damage and Activation of STING
Chlorin e6-Induced Photodynamic Effect Polarizes the Macrophage Into an M1 Phenotype Through Oxidative DNA Damage and Activation of STING Open
The tumor-associated macrophage (TAM) serves as an immunosuppressive agent in the malignant tumor microenvironment, facilitating the development and metastasis of lung cancer. The photodynamic effect destabilizes cellular homeostasis owing…
View article: Clinical significance of <scp>TM</scp>4<scp>SF</scp>1 as a tumor suppressor gene in gastric cancer
Clinical significance of <span>TM</span>4<span>SF</span>1 as a tumor suppressor gene in gastric cancer Open
Transmembrane‐4‐L‐six‐family member‐1 ( TM 4 SF 1), a tumor‐associated antigen, is overexpressed in most epithelial cell carcinomas and a potential target for antibody‐mediated therapy. However, the role of TM 4 SF 1 in gastric cancer has …
View article: Development of Whole Slide Imaging on Smartphones and Evaluation With ThinPrep Cytology Test Samples: Follow-Up Study
Development of Whole Slide Imaging on Smartphones and Evaluation With ThinPrep Cytology Test Samples: Follow-Up Study Open
Limited by hardware and operating system support, the performance of sWSI on mainstream Android smartphones did not fully match the iOS version. However, in practice, this difference was not significant, and both were adequate for digitizi…
View article: Genetic polymorphisms of IL-6 promoter in cancer susceptibility and prognosis: a meta-analysis
Genetic polymorphisms of IL-6 promoter in cancer susceptibility and prognosis: a meta-analysis Open
IL-6 is critical for tumorigenesis. However, previous studies on the association of IL-6 promoter polymorphisms with predisposition to different cancer types are somewhat contradictory. Therefore, we performed this meta-analysis regarding …
View article: Tooth loss and cancer risk: a dose-response meta analysis of prospective cohort studies
Tooth loss and cancer risk: a dose-response meta analysis of prospective cohort studies Open
Conflicting results to identify the relationship between tooth loss and cancer risk. Therefore, a dose-response meta-analysis was performed to clarify and quantitative assessed the correlation between tooth loss and cancer risk. Up to Marc…
View article: Development of Whole Slide Imaging on Smartphones and Evaluation With ThinPrep Cytology Test Samples: Follow-Up Study (Preprint)
Development of Whole Slide Imaging on Smartphones and Evaluation With ThinPrep Cytology Test Samples: Follow-Up Study (Preprint) Open
BACKGROUND The smartphone-based whole slide imaging (WSI) system represents a low-cost and effective alternative to automatic scanners for telepathology. In a previous study, the development of one such solution, named scalable whole slid…
View article: Development of Whole Slide Imaging on Smartphones and Evaluation With ThinPrep Cytology Test Samples: Follow-Up Study
Development of Whole Slide Imaging on Smartphones and Evaluation With ThinPrep Cytology Test Samples: Follow-Up Study Open
Background:The smartphone-based whole slide imaging (WSI) system represents a low-cost and effective alternative to automatic scanners for telepathology.In a previous study, the development of one such solution, named scalable whole slide …
View article: Nonsteroidal anti-inflammatory drugs using and risk of head and neck cancer: a dose-response meta analysis of prospective cohort studies
Nonsteroidal anti-inflammatory drugs using and risk of head and neck cancer: a dose-response meta analysis of prospective cohort studies Open
Conflicting results identifying the relationship between nonsteroidal anti-inflammatory drugs using and head and neck cancer risk. Therefore, we performed this meta-analysis to clarify and quantitative assessed the relationship between non…
View article: Genetic polymorphisms of Bcl-2 promoter in cancer susceptibility and prognosis: a meta-analysis
Genetic polymorphisms of Bcl-2 promoter in cancer susceptibility and prognosis: a meta-analysis Open
Bcl-2 is critical for tumorigenesis. However, previous studies on the association of Bcl-2 promoter polymorphisms with predisposition to different cancer types are somewhat contradictory. Therefore, we performed this meta-analysis regardin…