Explanipedia

Transcriptomic Analysis of Anthocyanin Degradation in Salix alba Bark: Insights into Seasonal Adaptation and Forestry Applications Open

Hongyong Wang, Xingju Liu, Mingliang Yin, Shuzhen Cui, Haiyong Liang , et al. · 2025

Anthocyanins, key flavonoid-derived secondary metabolites, not only confer diverse pigmentation but also function in photoprotection, antioxidative defense, and cold acclimation. In woody species, bark anthocyanin turnover is tightly linke…

Chemical composition analysis of the essential oil of Anthemis moghanica Iranshahr from Asteraceae and evaluation of its biological properties Open

Xingju Liu, Lina Liang, Reza Heidari · 2025

Clinical characteristics and prognosis of acute stroke in pregnancy and puerperium (ASPP) patients and their offspring: a retrospective, observational, nationwide, multicenter study protocol Open

Zhiyong Zhang, Zihan Yin, Tong Liu, Xiaolin Zhang, Qihang Zhang , et al. · 2025

Background Previous studies on the risk factors and prognosis of acute stroke in pregnancy and puerperium (ASPP) mainly used European and American national healthcare databases, lacking detailed patient-level data and precise event timing.…

MoOC-Mo2C/C heterojunction enables fast water dissociation for efficient alkaline hydrogen evolution reaction Open

Yulei Ren, Xuming Zhang, Hao Song, Chaoran Pi, Jianping Kelvin Li , et al. · 2025

<i>RNF213</i> Variant and Infectious Burden Associated With Intracranial Artery Stenosis in Moyamoya Disease Open

Chaofan Zeng, Peicong Ge, Zihan Yin, Junlin Lu, Xiaofan Yu , et al. · 2025

Background The mechanisms driving the progression of moyamoya disease (MMD) remain unrecognized. There is evidence suggesting that genetic and environmental factors may be associated with intracranial artery stenosis. Here, we aimed to inv…

Reorganization of Gray Matter Networks in Patients with Moyamoya Disease Open

Huan Zhu, Peijiong Wang, Wenjie Li, Qihang Zhang, Chenyu Zhu , et al. · 2024

Patients with Moyamoya disease (MMD) exhibit significant alterations in brain structure and function but knowledge regarding gray matter networks is limited. The study enrolled 136 MMD patients and 99 healthy controls (HCs). Clinical chara…

Gut microbiota in adults with moyamoya disease: characteristics and biomarker identification Open

Xiaofan Yu, Peicong Ge, Yuanren Zhai, Wei Liu, Qian Zhang , et al. · 2023

Background and purpose When it comes to the onset of moyamoya disease (MMD), environmental variables are crucial. Furthermore, there is confusion about the relationship between the gut microbiome, an environmental variable, and MMD. Conseq…

Plasma urea cycle metabolite levels and the risk of moyamoya disease Open

Xiaofan Yu, Peicong Ge, Yuanren Zhai, Wei Liu, Qian Zhang , et al. · 2023

Background and purpose Urea cycle metabolites are expected to be the biomarkers for cerebrovascular diseases. However, the effects of circulating urea cycle metabolites on the risk of MMD and its subcategories remain unclear. The aim of th…

Correlation of Serum N-Acetylneuraminic Acid with the Risk of Moyamoya Disease Open

Chenglong Liu, Peicong Ge, Chaofan Zeng, Xiaofan Yu, Yuanren Zhai , et al. · 2023

N-acetylneuraminic acid (Neu5Ac) is a functional metabolite and has been demonstrated to be a risk factor for cardiovascular diseases. It is not clear whether Neu5Ac is associated with a higher risk of cerebrovascular disorders, especially…

Prevalence and Procedural Risk of Intracranial Atherosclerotic Stenosis Coexisting With Unruptured Intracranial Aneurysm Open

Zihan Yin, Qihang Zhang, Yahui Zhao, Junlin Lu, Peicong Ge , et al. · 2023

Background: Coexistence of intracranial atherosclerotic stenosis (ICAS) and unruptured intracranial aneurysms (UIAs) is increasingly encountered in clinical practice. This study aims to determine the prevalence of ICAS in patients with UIA…

Association between systemic immune-inflammatory markers and the risk of moyamoya disease: a case-control study Open

Wei Liu, Chenglong Liu, Xiaofan Yu, Yuanren Zhai, Qiheng He , et al. · 2023

Background: Systemic immune-inflammatory markers such as neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), lymphocyte-to-monocyte ratio (LMR) and systemic immune-inflammatory index (SII) are associated with t…

Serum Kynurenic Acid and Kynurenine Are Negatively Associated with the Risk of Adult Moyamoya Disease Open

Xiaofan Yu, Peicong Ge, Yuanren Zhai, Wei Liu, Qian Zhang , et al. · 2022

Background and aim. Kynurenine (KYN) and kynurenic acid (KYNA) are key intermediate metabolites associated with inflammation and immune responses in the kynurenine pathway. It remains unknown whether KYN or KYNA is associated with the risk…

Association of circulating branched-chain amino acids with risk of moyamoya disease Open

Chaofan Zeng, Peicong Ge, Chenglong Liu, Xiaofan Yu, Yuanren Zhai , et al. · 2022

Objective Branched-Chain Amino Acids (BCAAs) has been identified as a risk factor for circulatory disease. Nevertheless, the effects and mechanisms of BCAAs on the risk of moyamoya disease (MMD) remain unrecognized. Hence, we aimed to eluc…

Collateral Predictors of Neovascularization After Indirect Revascularization in Adult Patients with Moyamoya Disease: A Single-Center Retrospective Study Open

Kefang Dai, Zhiyong Shi, Xingju Liu, Rong Wang, Yan Zhang , et al. · 2021

Objective. The underlying factors of neovascularization after indirect bypass in the adult patients with moyamoya disease (MMD) remained unknow. The aim of this study was to explore potential predictors based on collateral characteristics …

Different subtypes of collateral vessels in hemorrhagic moyamoya disease with p.R4810K variant Open

Peicong Ge, Qian Zhang, Xun Ye, Xingju Liu, Xiaofeng Deng , et al. · 2020

RNF213 gene polymorphism rs9916351 and rs8074015 significantly associated with moyamoya disease in Chinese population Open

Bin Zhu, Xingju Liu, Xueke Zhen, Xixi Li, Mingfen Wu , et al. · 2020

Our results had revealed the polymorphism of RNF213 rs9916351 and rs8074015 were significantly associated with MMD especially in Chinese population.

Efficacy of Surgical Revascularizations in Young and Middle-aged Patients with Symptomatic Middle Cerebral Arterial Occlusion Open

Mingze Wang, Xingju Liu, Ye‐Xuan Cao, Yan Zhang, Yuanli Zhao , et al. · 2020

Background: Treatments on middle cerebral arterial occlusions (MCAO) remain controversial. This study aims at investigating efficacies of surgical revascularizations in young and middle-aged patients (aged 18-65 y) with symptomatic MCAO, a…

Different Subtypes of Collateral Vessels in Hemorrhagic Moyamoya Disease with p.R4810K Variant Open

Peicong Ge, Qian Zhang, Xun Ye, Xingju Liu, Xiaofeng Deng , et al. · 2020

Background The aim of this study was to investigate the hemorrhgic sites and collateral vessels in hemorrhagic MMD with the p.R4810K variant. Methods Hemorrhage sites were classified as either anterior or posterior. Collateral vessels were…

A Treatment Option for Symptomatic Chronic Complete Internal Carotid Artery Occlusion: Hybrid Surgery Open

Yunna Yang, Xingju Liu, Rong Wang, Yan Zhang, Dong Zhang , et al. · 2020

Hybrid surgery might be safe and effective for patients with symptomatic chronic complete ICAO. The level of distal ICA reconstitution is a predictor of successful recanalization in hybrid operations.

Combined STA-MCA Bypass and Encephalodurosynangiosis Versus Encephalodurosynangiosis Alone in Adult Hemorrhagic Moyamoya Disease: A 5 -Year Outcome Study Open

Mingzhe Zhang, Raynald, Dong Zhang, Xingju Liu, Rong Wang , et al. · 2020

Efficacy of Surgical Revascularizations in Young and Middle-aged Patients with Symptomatic Middle Cerebral Arterial Occlusion Open

Mingze Wang, Xingju Liu, Yong Cao, Yan Zhang, Yuanli Zhao , et al. · 2020

Background: Treatments on middle cerebral arterial occlusions (MCAO) remain controversial. This study aims at investigating efficacies of surgical revascularizations in young and middle-aged patients (aged 18-65 y) with symptomatic MCAO, a…

Digital subtraction angiographic characteristics of progression of moyamoya disease 6 months prior to surgical revascularisation Open

Peicong Ge, Qian Zhang, Xun Ye, Xingju Liu, Xiaofeng Deng , et al. · 2020

Background Evidence on the natural angiographic course of moyamoya disease (MMD) is lacking. It takes about 6 months for waiting for revascularisation surgery. The issue of when to perform subtraction angiography (DSA) for follow-up remain…

Postoperative collateral formation after indirect bypass for hemorrhagic moyamoya disease Open

Peicong Ge, Qian Zhang, Xun Ye, Xingju Liu, Xiaofeng Deng , et al. · 2020

Postoperative collateral formation after indirect bypass for hemorrhagic moyamoya disease Open

Peicong Ge, Qian Zhang, Xun Ye, Xingju Liu, Xiaofeng Deng , et al. · 2020

Background: The research on postoperative collateral formation for hemorrhagic moyamoya disease (MMD) evaluated by using digital subtraction angiography (DSA) is limited. Our study objective was to investigate the postoperative collateral …

Association between neoangiogenesis after first and second indirect bypass in moyamoya disease Open

Peicong Ge, Qian Zhang, Xun Ye, Xingju Liu, Xiaofeng Deng , et al. · 2020

Background The research on neoangiogenesis after indirect bypass for moyamoya disease (MMD) evaluated by using digital subtraction angiography (DSA) is limited. Our study objective was to investigate association between neoangiogenesis aft…

Postoperative collateral formation after indirect bypass for hemorrhagic moyamoya disease Open

Peicong Ge, Qian Zhang, Xun Ye, Xingju Liu, Xiaofeng Deng , et al. · 2019

Background: The research on postoperative collateral formation for hemorrhagic moyamoya disease (MMD) evaluated by using digital subtraction angiography (DSA) is limited. Our study objective was to investigate the postoperative collateral …

Cognitive Performance Profile in Pediatric Moyamoya Disease Patients and Its Relationship With Regional Cerebral Blood Perfusion Open

Jiaxi Li, Xingju Liu, Dong Zhang, Yan Zhang, Rong Wang , et al. · 2019

Object: Moyamoya disease affects the cognitive function of pediatric patients, and compromised cerebral blood flow might be the potential cause. We aimed to explore the specific correlation between cognitive impairment and regional …

Angiographic Outcomes of Direct and Combined Bypass Surgery in Moyamoya Disease Open

Peicong Ge, Xun Ye, Xingju Liu, Xiaofeng Deng, Wang Jia , et al. · 2019

Objective: To identify associated risk factors for the angiographic outcomes after direct and combined bypass surgery in moyamoya disease (MMD). Methods: All direct and combined bypass procedures performed from June 2009 to M…

Postoperative collateral formation after indirect bypass for hemorrhagic moyamoya disease Open

Peicong Ge, Qian Zhang, Xun Ye, Xingju Liu, Xiaofeng Deng , et al. · 2019

Background: The study on postoperative collateral formation for hemorrhagic moyamoya disease (MMD) evaluated by using digital subtraction angiography (DSA) is limited. Our study objective was to investigate the postoperative collateral for…

Association Between p.R4810K Variant and Long-Term Clinical Outcome in Patients With Moyamoya Disease Open

Peicong Ge, Xun Ye, Xingju Liu, Xiaofeng Deng, Rong Wang , et al. · 2019

Objective: To estimate the association between p. R4810K variant and clinical outcomes of patients with moyamoya disease (MMD). Methods: The p.R4810K genetic variant was genotyped among 498 Chinese patients with MMD conducted…

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