Xiaoyuan Xu
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View article: Overexpression of GmbZIP59 Confers Broad-Spectrum Stress Resistance in Arabidopsis thaliana and Rice (Oryza sativa)
Overexpression of GmbZIP59 Confers Broad-Spectrum Stress Resistance in Arabidopsis thaliana and Rice (Oryza sativa) Open
Soybean (Glycine max) is a vital oilseed and economic crop in China, often constrained by drought, salinity, and biotic stresses. In this study, we identified a soybean bZIP transcription factor, GmbZIP59, whose expression is upregulated b…
View article: Reconstruction and quality control of non-repeatable land time-lapse seismic data
Reconstruction and quality control of non-repeatable land time-lapse seismic data Open
Onshore non-repeatable time-lapse (TL) seismic exploration is a challenging yet convenient technique for enhancing production in mature oil and gas fields. Data repeatability across two or more acquisition phases is fundamental for reliabl…
View article: Quantitatively Evaluate the Improvement of Functional Cure for the Quality of Life of Chronic Hepatitis B Cases: Evidence from a Cross-Sectional Study in China
Quantitatively Evaluate the Improvement of Functional Cure for the Quality of Life of Chronic Hepatitis B Cases: Evidence from a Cross-Sectional Study in China Open
Background: Functional cure of chronic hepatitis B (CHB) can be achieved with appropriate antiviral treatment. However, few studies have evaluated the added benefits of achieving functional cure. We aimed to conduct a quantitative analysis…
View article: Consensus on the Management of Liver Injury Associated with Targeted Drugs and Immune Checkpoint Inhibitors for Hepatocellular Carcinoma (Version 2024)
Consensus on the Management of Liver Injury Associated with Targeted Drugs and Immune Checkpoint Inhibitors for Hepatocellular Carcinoma (Version 2024) Open
With the widespread application of systemic treatments for hepatocellular carcinoma, liver injury caused by molecular targeted drugs and immune checkpoint inhibitors has become a common clinical problem. The Chinese Society of Hepatology, …
View article: A real-world study of polyenyl phosphatidylcholine in the management of patients with metabolic dysfunction-associated fatty liver disease in China clinical practice
A real-world study of polyenyl phosphatidylcholine in the management of patients with metabolic dysfunction-associated fatty liver disease in China clinical practice Open
Background/Objectives Metabolic dysfunction-associated fatty liver disease (MAFLD) is highly prevalent in China. Clinical evidence supporting the role of polyenyl phosphatidylcholine (PPC) in delaying liver fibrosis in patients with MAFLD …
View article: Impact of Alanine Transaminase Thresholds on Treatment Eligibility of Patients with Chronic Hepatitis B: A Cross-sectional Study of the China Registry of Hepatitis B
Impact of Alanine Transaminase Thresholds on Treatment Eligibility of Patients with Chronic Hepatitis B: A Cross-sectional Study of the China Registry of Hepatitis B Open
View article: Chinese Expert Consensus for the Management of Thrombocytopenia in Cirrhosis
Chinese Expert Consensus for the Management of Thrombocytopenia in Cirrhosis Open
Thrombocytopenia in cirrhosis presents significant challenges in clinical practice. To help clinicians rapidly understand and standardize the diagnosis and treatment of this condition, the Liver Fibrosis, Cirrhosis, and Portal Hypertension…
View article: Advances in Small RNA Regulation of Female Gametophyte Development in Flowering Plants
Advances in Small RNA Regulation of Female Gametophyte Development in Flowering Plants Open
Female gametophyte development in flowering plants is a highly intricate process involving a series of tightly regulated biological events, including the establishment and differentiation of a macrospore mother cell (MMC), the formation of…
View article: Overexpression of the Transcription Factor GmbZIP60 Increases Salt and Drought Tolerance in Soybean (Glycine max)
Overexpression of the Transcription Factor GmbZIP60 Increases Salt and Drought Tolerance in Soybean (Glycine max) Open
The regulation of downstream responsive genes by transcription factors (TFs) is a critical step in the stress response system of plants. While bZIP transcription factors are known to play important roles in stress reactions, their function…
View article: Chinese Guidelines on the Management of Hepatic Encephalopathy in Cirrhosis (2024)
Chinese Guidelines on the Management of Hepatic Encephalopathy in Cirrhosis (2024) Open
With progress in basic and clinical research on hepatic encephalopathy in cirrhosis worldwide, the Chinese Society of Hepatology of the Chinese Medical Association has invited experts in relevant fields to revise the 2018 "Chinese Guidelin…
View article: Interobserver consistency and diagnostic challenges in HER2-ultralow breast cancer: a multicenter study
Interobserver consistency and diagnostic challenges in HER2-ultralow breast cancer: a multicenter study Open
The low consistency among pathologists in distinguishing HER2-null, -ultralow, and 1+ cases may impact patient eligibility for new ADC therapies. To address this challenge, there is a need for improved detection methods, artificial intelli…
View article: Baseline <scp>FIB</scp> ‐4 May Be a Risk Factor of Recurrence After <scp>SBRT</scp> in Patients With <scp>HBV</scp> ‐Related Small <scp>HCC</scp>
Baseline <span>FIB</span> ‐4 May Be a Risk Factor of Recurrence After <span>SBRT</span> in Patients With <span>HBV</span> ‐Related Small <span>HCC</span> Open
Aims Exploring fibrosis index‐4 (FIB‐4)'s predictive value for HBV‐related hepatocellular carcinoma (HCC) in assessing recurrence following stereotactic body radiation therapy (SBRT) in patients with HBV‐related HCC. Methods HBV‐related HC…
View article: Spatio-Temporal Load Simulation of Integrated Electric Vehicle Charging and Battery Swapping Station
Spatio-Temporal Load Simulation of Integrated Electric Vehicle Charging and Battery Swapping Station Open
View article: Guideline for the Prevention and Treatment of Metabolic Dysfunction-associated Fatty Liver Disease (Version 2024)
Guideline for the Prevention and Treatment of Metabolic Dysfunction-associated Fatty Liver Disease (Version 2024) Open
With the rising epidemic of obesity, metabolic syndrome, and type 2 diabetes mellitus in China, metabolic dysfunction-associated non-alcoholic fatty liver disease has become the most prevalent chronic liver disease. This condition frequent…
View article: Pancancer analysis of the interactions between CTNNB1 and infiltrating immune cell populations
Pancancer analysis of the interactions between CTNNB1 and infiltrating immune cell populations Open
Recently, evidence has indicated that CTNNB1 is important in a variety of malignancies. However, how CTNNB1 interacts with immune cell infiltration remains to be further investigated. In this study, we focused on the correlations between C…
View article: Global multi-societies endorsement of the MAFLD definition
Global multi-societies endorsement of the MAFLD definition Open
View article: Durability and on-treatment predictors of recompensation in entecavir-treated patients with hepatitis B and decompensated cirrhosis
Durability and on-treatment predictors of recompensation in entecavir-treated patients with hepatitis B and decompensated cirrhosis Open
Our research provides a meaningful contribution to understanding the long-term prognosis of recompensation in patients with chronic hepatitis B and decompensated cirrhosis, as well as to evaluating the predictive value of serum albumin lev…
View article: Inflammation-related molecular signatures involved in the anticancer activities of brigatinib as well as the prognosis of EML4-ALK lung adenocarcinoma patient
Inflammation-related molecular signatures involved in the anticancer activities of brigatinib as well as the prognosis of EML4-ALK lung adenocarcinoma patient Open
View article: The association between serum prolactin levels and live birth rates in non-PCOS patients: A retrospective cohort study
The association between serum prolactin levels and live birth rates in non-PCOS patients: A retrospective cohort study Open
Background and objectives This paper aimed to analyze the relationship between baseline prolactin (PRL) levels and live birth rates (LBRs) in patients undergoing embryo transfer who did not have polycystic ovarian syndrome (PCOS) using a r…
View article: Guidelines for the Management of Esophagogastric Variceal Bleeding in Cirrhotic Portal Hypertension
Guidelines for the Management of Esophagogastric Variceal Bleeding in Cirrhotic Portal Hypertension Open
To standardize the diagnosis, treatment, and management of esophagogastric variceal bleeding (EVB) in patients with cirrhotic portal hypertension, the Chinese Society of Hepatology, the Chinese Society of Gastroenterology, and the Chinese …
View article: Safety of entecavir antiviral therapyduring an accidental pregnancy in patients with chronic hepatitis B
Safety of entecavir antiviral therapyduring an accidental pregnancy in patients with chronic hepatitis B Open
The present study aimed to investigate the effects of accidental pregnancy CHB patients' reproductive age on their offspring during entecavir (ETV) antiviral therapy. A total of 112 couples were retrospectively enrolled, and they were divi…
View article: Guidelines for the Prevention and Treatment of Chronic Hepatitis B (version 2022)
Guidelines for the Prevention and Treatment of Chronic Hepatitis B (version 2022) Open
To facilitate the achieving of the goal of "eliminating viral hepatitis as a major public health threat by 2030" set by the World Health Organization, the Chinese Society of Hepatology together with the Chinese Society of Infectious Diseas…
View article: Lower end of treatment HBsAg and HBcrAg were associated with HBsAg loss after nucleos(t)ide analog cessation
Lower end of treatment HBsAg and HBcrAg were associated with HBsAg loss after nucleos(t)ide analog cessation Open
Background Since hepatitis B surface antigen (HBsAg) loss is rarely achieved with nucleos(t)ide analog (NA) treatment, most patients require life-long NA treatment. Previous studies have shown that some patients remain virologically respon…
View article: Consensus on the tertiary prevention of primary liver cancer
Consensus on the tertiary prevention of primary liver cancer Open
To effectively prevent recurrence, improve the prognosis and increase the survival rate of primary liver cancer (PLC) patients with radical cure, the Chinese Society of Hepatology, Chinese Medical Association, invited clinical experts and …
View article: Baicalin suppress the development of polycystic ovary syndrome via regulating the miR-874-3p/FOXO3 and miR-144/FOXO1 axis
Baicalin suppress the development of polycystic ovary syndrome via regulating the miR-874-3p/FOXO3 and miR-144/FOXO1 axis Open
Baicalin could alleviate the symptoms of PCOS via regulating miR-874-3p/FOXO3 and miR-144/FOXO1 axis, demonstrating its potential utility in PCOS treatment.
View article: The Impact of the Definitions of Clinical Phases on the Profiles of Grey-Zone Patients with Chronic Hepatitis B Virus Infection
The Impact of the Definitions of Clinical Phases on the Profiles of Grey-Zone Patients with Chronic Hepatitis B Virus Infection Open
We aim to investigate the impact of different clinical phases’ definitions of chronic hepatitis B (CHB) infection on the profiles of grey zone, based on HBV guidelines set by the Chinese Society of Hepatology and Chinese Society of Infecti…
View article: HBsAg ≤ 135 IU/mL or HBcrAg ≤ 3.6 logU/mL was associated with HBsAg loss after nucleos(t)ide analogue cessation
HBsAg ≤ 135 IU/mL or HBcrAg ≤ 3.6 logU/mL was associated with HBsAg loss after nucleos(t)ide analogue cessation Open
Background Since hepatitis B surface antigen (HBsAg) loss is rarely achieved with nucleos(t)ide analogue (NA) treatment, most patients require life-long NA treatment. Previous studies have shown that a proportion of patients remained virol…
View article: Cost-effectiveness of expanded antiviral treatment for chronic hepatitis B virus infection in China: an economic evaluation
Cost-effectiveness of expanded antiviral treatment for chronic hepatitis B virus infection in China: an economic evaluation Open
View article: Guidelines on the Diagnosis and Management of Primary Biliary Cholangitis (2021)
Guidelines on the Diagnosis and Management of Primary Biliary Cholangitis (2021) Open
In 2015, the Chinese Society of Hepatology and the Chinese Society of Gastroenterology published a consensus on primary biliary cholangitis (PBC). In the past years, numerous clinical studies have been published in the field of PBC. To gui…
View article: Impact of Different ALT Thresholds on the Treatment Eligibility of Patients with CHB
Impact of Different ALT Thresholds on the Treatment Eligibility of Patients with CHB Open