Xingru Zhang
YOU?
Author Swipe
View article: Huachansu-derived Bufotalin Potentiates CD8+ T Cell Effector and Memory Function via Stabilization of the IL-2/IL-2R Complex in Colorectal Cancer
Huachansu-derived Bufotalin Potentiates CD8+ T Cell Effector and Memory Function via Stabilization of the IL-2/IL-2R Complex in Colorectal Cancer Open
View article: Curcumin as a therapeutic agent in liver cancer: a systematic review of preclinical models and mechanisms
Curcumin as a therapeutic agent in liver cancer: a systematic review of preclinical models and mechanisms Open
View article: Correction: A comprehensive review of rehabilitation approaches for traumatic brain injury: efficacy and outcomes
Correction: A comprehensive review of rehabilitation approaches for traumatic brain injury: efficacy and outcomes Open
[This corrects the article DOI: 10.3389/fneur.2025.1608645.].
View article: A comprehensive review of rehabilitation approaches for traumatic brain injury: efficacy and outcomes
A comprehensive review of rehabilitation approaches for traumatic brain injury: efficacy and outcomes Open
Traumatic Brain Injury (TBI), particularly in moderate-to-severe cases, remains a leading cause of long-term disability worldwide, affecting over 64 million individuals annually. Its complex and multifactorial nature demands an integrated,…
View article: The role of interleukin-17 in inflammation-related cancers
The role of interleukin-17 in inflammation-related cancers Open
Emerging evidence indicates a correlation between inflammation and the development and progression of cancer. Among the various inflammatory signals, interleukin-17 (IL-17) family cytokines serve as a critical link between inflammation and…
View article: The Effect of Bovine Colostrum Supplementation on Secretory Immunoglobulin A and Health Status in Middle-aged and Elderly people: A Double-Blind, Randomized, Controlled Trial
The Effect of Bovine Colostrum Supplementation on Secretory Immunoglobulin A and Health Status in Middle-aged and Elderly people: A Double-Blind, Randomized, Controlled Trial Open
Background: The rapid population aging is becoming a serious health crisis. This study aims to evaluate the effects of bovine colostrum supplementation on enhancing Secretory immunoglobulin A and health in middle-aged and elderly people. M…
View article: Rujifang inhibits triple-negative breast cancer growth via the PI3K/AKT pathway
Rujifang inhibits triple-negative breast cancer growth via the PI3K/AKT pathway Open
Rujifang (RJF) constitutes a traditional Chinese medicinal compound extensively employed in the management of triple-negative breast cancer (TNBC). However, information regarding its potential active ingredients, antitumor effects, safety,…
View article: A follow-up study on factors affecting the recovery of patients with hypothyroidism in different selenium environments
A follow-up study on factors affecting the recovery of patients with hypothyroidism in different selenium environments Open
Background Hypothyroidism is a major manifestation of autoimmune thyroid diseases (AITD). We previously reported that a low selenium (Se) status was linked to an elevated prevalence of thyroid diseases. We hypothesized that Se status may a…
View article: Huachansu Enhances the Memory Function of Cd8+ T Cells in Colorectal Cancer by Directly Binding to the Il-2 Receptor
Huachansu Enhances the Memory Function of Cd8+ T Cells in Colorectal Cancer by Directly Binding to the Il-2 Receptor Open
View article: A follow-up study on factors affecting the rehabilitation of patients with hypothyroidism in different selenium environments
A follow-up study on factors affecting the rehabilitation of patients with hypothyroidism in different selenium environments Open
Background Hypothyroidism is a key manifestation of autoimmune thyroid disease (AITD). Our previous research has found that low selenium (Se) status was linked to an elevated prevalence and incidence of thyroid diseases. We hypothesized th…
View article: Research Progress of Laser Cladding on the Surface of Titanium and Its Alloys
Research Progress of Laser Cladding on the Surface of Titanium and Its Alloys Open
Titanium (Ti) and its alloys have been widely employed in aeronautical, petrochemical, and medical fields owing to their fascinating advantages in terms of their mechanical properties, corrosion resistance, biocompatibility, and so on. How…
View article: Comprehensive evaluations of individual discrimination, kinship analysis, genetic relationship exploration and biogeographic origin prediction in Chinese Dongxiang group by a 60-plex DIP panel
Comprehensive evaluations of individual discrimination, kinship analysis, genetic relationship exploration and biogeographic origin prediction in Chinese Dongxiang group by a 60-plex DIP panel Open
View article: Genetic polymorphisms and population genetic analyses of 57 autosomal InDel loci in Hubei Tujia group
Genetic polymorphisms and population genetic analyses of 57 autosomal InDel loci in Hubei Tujia group Open
Introduction: The Tujia is the eighth most populous population in China, but its genetic structure has not been fully studied. Methods: In this study, we utilized 57 autosomal Insertion/deletion (InDel) loci to evaluate the genetic polymor…
View article: A Research on Delayed Thermal Depolarization, Electric Properties, and Stress in (Bi0.5Na0.5)TiO3-Based Ceramic Composites
A Research on Delayed Thermal Depolarization, Electric Properties, and Stress in (Bi0.5Na0.5)TiO3-Based Ceramic Composites Open
Depolarization behavior is one of the main shortcomings of (Bi0.5Na0.5)TiO3-based ceramics. Considering the undesirable efficiency of traditional modification methods, in this paper a series of 0–3 type ceramic composites 0.85(Bi0.5Na0.5)T…
View article: Improved Non-Piezoelectric Electric Properties Based on La Modulated Ferroelectric-Ergodic Relaxor Transition in (Bi0.5Na0.5)TiO3-Ba(Ti, Zr)O3 Ceramics
Improved Non-Piezoelectric Electric Properties Based on La Modulated Ferroelectric-Ergodic Relaxor Transition in (Bi0.5Na0.5)TiO3-Ba(Ti, Zr)O3 Ceramics Open
The characteristic transition from ferroelectric (FE) to ergodic relaxor (ER) state in (Bi0.5Na0.5)TiO3 (BNT) based lead-free ceramics provides an efficient approach to bring a highly ordered phase back to a disordered one. It would be rat…
View article: Multifunctional, Robust, and Porous PHBV—GO/MXene Composite Membranes with Good Hydrophilicity, Antibacterial Activity, and Platelet Adsorption Performance
Multifunctional, Robust, and Porous PHBV—GO/MXene Composite Membranes with Good Hydrophilicity, Antibacterial Activity, and Platelet Adsorption Performance Open
The limitations of hydrophilicity, strength, antibacterial activity adsorption performance of the biobased and biocompatible polymer materials, such as polyhydroxyalkanoates (PHAs), significantly restrict their wider applications especiall…
View article: Comprehensive Insights Into Forensic Features and Genetic Background of Chinese Northwest Hui Group Using Six Distinct Categories of 231 Molecular Markers
Comprehensive Insights Into Forensic Features and Genetic Background of Chinese Northwest Hui Group Using Six Distinct Categories of 231 Molecular Markers Open
The Hui minority is predominantly composed of Chinese-speaking Islamic adherents distributed throughout China, of which the individuals are mainly concentrated in Northwest China. In the present study, we employed the length and sequence p…
View article: Characterizing slopes for torus knots, II
Characterizing slopes for torus knots, II Open
A slope $\frac pq$ is called a characterizing slope for a given knot $K_0\subset S^3$ if whenever the $\frac pq$--surgery on a knot $K\subset S^3$ is homeomorphic to the $\frac pq$--surgery on $K_0$ via an orientation preserving homeomorph…
View article: Influence of Multi-Pass Hot Extrusion on Microstructure and Mechanical Properties of the Mg–4Zn–1.2Y–0.8Nd Alloy
Influence of Multi-Pass Hot Extrusion on Microstructure and Mechanical Properties of the Mg–4Zn–1.2Y–0.8Nd Alloy Open
In the present research, a Mg–4Zn–1.2Y–0.8Nd (wt.%) alloy was heat treated and hot extruded with different passes. XRD, SEM, TEM and tensile testing were employed to characterize the microstructure evolution and mechanical properties. The …
View article: A Novel Panel of 43 Insertion/Deletion Loci for Human Identifications of Forensic Degraded DNA Samples: Development and Validation
A Novel Panel of 43 Insertion/Deletion Loci for Human Identifications of Forensic Degraded DNA Samples: Development and Validation Open
Insertion/deletion polymorphism is a promising genetic marker in the forensic genetic fields, especially in the forensic application of degraded sample at crime scene. In this research, a novel five-dye multiplex amplification panel contai…
View article: Genetic Polymorphisms of 44 Y Chromosomal Genetic Markers in the Inner Mongolia Han Population and Its Genetic Relationship Analysis with Other Reference Populations
Genetic Polymorphisms of 44 Y Chromosomal Genetic Markers in the Inner Mongolia Han Population and Its Genetic Relationship Analysis with Other Reference Populations Open
Y chromosomal genetic markers in the non-recombining region are commonly used for human evolution research, familial searching, and forensic male differentiation since they strictly follow paternal inheritance. Y chromosomal short tandem r…
View article: Genetic polymorphisms of 44 Y chromosomal genetic markers in the Inner Mongolia Han population and its genetic relationship analysis with other reference populations
Genetic polymorphisms of 44 Y chromosomal genetic markers in the Inner Mongolia Han population and its genetic relationship analysis with other reference populations Open
Y chromosomal genetic markers in the non-recombining region are commonly used for human evolution research, familial searching, and forensic male differentiation since they strictly follow paternal inheritance. Y chromosomal short tandem r…
View article: The Genetic Structure of Chinese Hui Ethnic Group Revealed by Complete Mitochondrial Genome Analyses Using Massively Parallel Sequencing
The Genetic Structure of Chinese Hui Ethnic Group Revealed by Complete Mitochondrial Genome Analyses Using Massively Parallel Sequencing Open
Mitochondrial DNA (mtDNA), coupled with maternal inheritance and relatively high mutation rates, provides a pivotal way for us to investigate the formation histories of populations. The Hui minority with Islamic faith is one of the most wi…
View article: A Highly Polymorphic Panel Consisting of Microhaplotypes and Compound Markers with the NGS and Its Forensic Efficiency Evaluations in Chinese Two Groups
A Highly Polymorphic Panel Consisting of Microhaplotypes and Compound Markers with the NGS and Its Forensic Efficiency Evaluations in Chinese Two Groups Open
Novel genetic markers like microhaplotypes and compound markers show promising potential in forensic research. Based on previously reported single nucleotide polymorphism (SNP) and insertion/deletion (InDel) polymorphism loci, 29 genetic m…
View article: Gene mapping and functional annotation of GWAS of oral ulcers using FUMA software
Gene mapping and functional annotation of GWAS of oral ulcers using FUMA software Open
View article: Dehn fillings of knot manifolds containing essential twice-punctured tori
Dehn fillings of knot manifolds containing essential twice-punctured tori Open
We show that if a hyperbolic knot manifold $M$ contains an essential twice-punctured torus $F$ with boundary slope $β$ and admits a filling with slope $α$ producing a Seifert fibred space, then the distance between the slopes $α$ and $β$ i…
View article: <p>The Advantages of Levodopa-Carbidopa Intestinal Gel for Patients with Advanced Parkinson’s Disease: A Systematic Review</p>
The Advantages of Levodopa-Carbidopa Intestinal Gel for Patients with Advanced Parkinson’s Disease: A Systematic Review Open
Compared with oral treatment, LCIG exerts its effectiveness, mostly by reducing the time of on-time with TSD, increasing the time of on-time without TSD and scores of UPDRS and PDQ-39. It is suggesting that LCIG was likely to be a new type…
View article: β-arrestin2 alleviates L-dopa–induced dyskinesia via lower D1R activity in Parkinson’s rats
β-arrestin2 alleviates L-dopa–induced dyskinesia via lower D1R activity in Parkinson’s rats Open
The cause of the L-dopa-induced dyskinesia (LID) has been ascribed to G-protein coupled receptor (GPCR) supersensitivity and uncontrolled downstream signaling. It is now supposed that β-arrestin2 affects GPCR signaling through its ability …
View article: Levodopa/Benserazide PLGA Microsphere Prevents L-Dopa–Induced Dyskinesia via Lower β-Arrestin2 in 6-Hydroxydopamine Parkinson’s Rats
Levodopa/Benserazide PLGA Microsphere Prevents L-Dopa–Induced Dyskinesia via Lower β-Arrestin2 in 6-Hydroxydopamine Parkinson’s Rats Open
Prolonged pulsatile administration of Levodopa (L-dopa) can generate L-dopa-induced dyskinesia (LID). Numerous research has reported that continuous dopamine delivery (CDD) was useful in reducing the severity of LID. 6-OHDA lesioned rats w…
View article: Remarks on SU(2)-simple knots and SU(2)-cyclic 3-manifolds
Remarks on SU(2)-simple knots and SU(2)-cyclic 3-manifolds Open
We give some remarks on two closely related issues as stated in the title. In particular we show that a Montesinos knot is SU(2)-simple if and only if it is a 2-bridge knot, extending a result of Zentner for 3-tangle summand pretzel knots.…