Xia Xu
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View article: The role of gut microbiota imbalance in preeclampsia pathogenesis: insights into FMO3-mediated inflammatory mechanisms
The role of gut microbiota imbalance in preeclampsia pathogenesis: insights into FMO3-mediated inflammatory mechanisms Open
Background Preeclampsia (PE) is a severe pregnancy complication linked to systemic inflammation and metabolic dysregulation. Emerging evidence suggests gut microbiota imbalance may contribute to PE pathogenesis, but the underlying mechanis…
View article: Magnetic Cotton Stalk Biochar for Rapid and Eco‐Friendly Extraction and Determination of Triazole Pesticides in Fruit Juices
Magnetic Cotton Stalk Biochar for Rapid and Eco‐Friendly Extraction and Determination of Triazole Pesticides in Fruit Juices Open
Triazole fungicides (TFs) are widely used but pose health risks. Among them, cyproconazole, paclobutrazol, tebuconazole, metconazole, and diniconazole have high exceedance rates and exhibit hepatotoxicity and nephrotoxicity, necessitating …
View article: Pulmonary function impairment and its relationship with target therapy response in patients with pulmonary arterial hypertension
Pulmonary function impairment and its relationship with target therapy response in patients with pulmonary arterial hypertension Open
Introduction Patients with pulmonary arterial hypertension (PAH) exhibit exertional dyspnea and decreased exercise capacity, which are not solely attributable to right heart dysfunction. Numerous studies have aimed to elucidate pulmonary f…
View article: Protein Kinase A Regulates the Cell Cycle to Affect the Induction Rate in the Parthenogenetic Reproduction of the Silkworm, Bombyx mori
Protein Kinase A Regulates the Cell Cycle to Affect the Induction Rate in the Parthenogenetic Reproduction of the Silkworm, Bombyx mori Open
Protein kinase A (PKA), commonly referred to as cAMP-dependent protein kinase, exists as a heterotetramer composed of two catalytic (C) and regulatory subunits (R). This versatile kinase exhibits regulatory functions in various biological …
View article: PPARs Activity Affects the Hatchability Through Lipid Metabolism Regulation in Silkworm, Bombyx mori L.
PPARs Activity Affects the Hatchability Through Lipid Metabolism Regulation in Silkworm, Bombyx mori L. Open
Lipid metabolism serves as the primary energy source for organisms. Silkworm eggs for spring use are divided into two types: autumn-produced eggs for next spring rearing (AS) and spring-produced eggs for next spring rearing (SS). Productio…
View article: MTFR2 promotes endometrial carcinoma cell proliferation and growth via the miR-132-3p/PI3K/Akt signaling pathway
MTFR2 promotes endometrial carcinoma cell proliferation and growth via the miR-132-3p/PI3K/Akt signaling pathway Open
Objective Understanding the mechanisms underlying endometrial cancer progression is crucial for the development of effective targeted therapies. In this study, we investigated the role of MTFR2 in endometrial cancer cell. Methods The expre…
View article: Black soldier fly: a new model for bioremediation of antibiotic pollutants
Black soldier fly: a new model for bioremediation of antibiotic pollutants Open
View article: 6587 Circulating androgen and estrogen metabolites associated with self-reported sleep quality and vasomotor symptoms in the Women’s Health Initiative Observational Study
6587 Circulating androgen and estrogen metabolites associated with self-reported sleep quality and vasomotor symptoms in the Women’s Health Initiative Observational Study Open
Disclosure: A.H. Arabi: None. B. Trabert: None. M. Allison: None. G. Anderson: None. J. Chervenak: None. C.J. Crandall: None. M. Gass: None. J. Gorzelitz: None. E.S. LeBlanc: None. H. Lieman: None. R.M. Pfeiffer: None. J. Wactawski-Wende: …
View article: Associations of tubal ligation and hysterectomy with serum androgen and estrogen metabolites among postmenopausal women in the Women’s Health Initiative Observational Study
Associations of tubal ligation and hysterectomy with serum androgen and estrogen metabolites among postmenopausal women in the Women’s Health Initiative Observational Study Open
View article: Comprehensive characterization of the compositional differences in essential oils prepared from Artemisiae argyi during different picking seasons using gas chromatography Orbitrap high-resolution mass spectrometry
Comprehensive characterization of the compositional differences in essential oils prepared from Artemisiae argyi during different picking seasons using gas chromatography Orbitrap high-resolution mass spectrometry Open
Background: Artemisia argyi Lévl. et Vant, commonly utilized in traditional medicine, food, and therapeutic practices such as moxibustion and fumigation, yields an essential oil with significant value. Understanding the chemical compositio…
View article: Comprehensive Characterization the Composition Differences of Essential Oils Prepared from Artemisiae Argyi in Different Picking Seasons by Gas Chromatography Orbitrap High-Resolution Mass Spectrometry
Comprehensive Characterization the Composition Differences of Essential Oils Prepared from Artemisiae Argyi in Different Picking Seasons by Gas Chromatography Orbitrap High-Resolution Mass Spectrometry Open
View article: 350 Harnessing arginine metabolism to overcome hyperthermia-induced metabolic dysfunction of CAR T-cells
350 Harnessing arginine metabolism to overcome hyperthermia-induced metabolic dysfunction of CAR T-cells Open
Background Chimeric antigen receptor (CAR) T-cells have shown remarkable success in the treatment of hematological malignancies, but many patients still relapse. One common adverse on-target effect of CAR T-cells is cytokine release syndro…
View article: A comprehensive evaluation of pre- and post-processing sperm parameters for predicting successful pregnancy rate following intrauterine insemination with the husband’s sperms
A comprehensive evaluation of pre- and post-processing sperm parameters for predicting successful pregnancy rate following intrauterine insemination with the husband’s sperms Open
View article: Sperm DNA integrity is critically impacted by male age but does not influence outcomes of artificial insemination by husband in the Chinese infertile couples
Sperm DNA integrity is critically impacted by male age but does not influence outcomes of artificial insemination by husband in the Chinese infertile couples Open
The sperm chromatin structure assay (SCSA) is crucial for assessing male fertility. However, the predictive value of the SCSA parameters, including the DNA fragment indices (DFI) and the percentages of high DNA stainability (HDS), for outc…
View article: Assessing the impact of blood pressure in the development of inflammatory bowel disease
Assessing the impact of blood pressure in the development of inflammatory bowel disease Open
The purpose of this study is to investigate the potential causal relationships between blood pressure and inflammatory bowel disease (IBD) by using the bidirectional Mendelian randomization (MR) approach. Summary‐level data for blood press…
View article: Circ_FURIN knockdown assuages Testosterone-induced human ovarian granulosa-like tumor cell disorders by sponging miR-423-5p to reduce MTM1 expression in polycystic ovary syndrome
Circ_FURIN knockdown assuages Testosterone-induced human ovarian granulosa-like tumor cell disorders by sponging miR-423-5p to reduce MTM1 expression in polycystic ovary syndrome Open
Background Polycystic ovary syndrome (PCOS) is a common endocrine disorder among reproductive-age women. The mechanism by which circular RNA (circRNA) drives PCOS development remains unclear. Thus, the study is designed to explore the role…
View article: Correction to: Relation of circulating estrogens with hair relaxer and skin lightener use among postmenopausal women in Ghana
Correction to: Relation of circulating estrogens with hair relaxer and skin lightener use among postmenopausal women in Ghana Open
View article: Measured body size and serum estrogen metabolism in postmenopausal women: the Ghana Breast Health Study
Measured body size and serum estrogen metabolism in postmenopausal women: the Ghana Breast Health Study Open
View article: Relation of circulating estrogens with hair relaxer and skin lightener use among postmenopausal women in Ghana
Relation of circulating estrogens with hair relaxer and skin lightener use among postmenopausal women in Ghana Open
View article: Kapok Fiber-Supported Liquid Extraction for Convenient Oil Samples Preparations: A Feasibility and Proof of Concept Study
Kapok Fiber-Supported Liquid Extraction for Convenient Oil Samples Preparations: A Feasibility and Proof of Concept Study Open
View article: Additional file 1 of Measured body size and serum estrogen metabolism in postmenopausal women: the Ghana Breast Health Study
Additional file 1 of Measured body size and serum estrogen metabolism in postmenopausal women: the Ghana Breast Health Study Open
Additional file 1: Supplemental Tables summarizing geometric means (pmol/L) and 95% CIs of serum estrogens/estrogen metabolites by current body mass index with additional adjustment for unconjugated estradiol (Table S1); by current body si…
View article: Urinary estrogen metabolites and gastric cancer risk among postmenopausal women
Urinary estrogen metabolites and gastric cancer risk among postmenopausal women Open
Background The overall incidence of gastric cancer in women is half that in men for most global populations. Sex hormone pathways may be involved in carcinogenesis and estrogens have been postulated to protect women against gastric cancer.…
View article: Developments in Fatty Acid-Derived Insect Pheromone Production Using Engineered Yeasts
Developments in Fatty Acid-Derived Insect Pheromone Production Using Engineered Yeasts Open
The use of traditional chemical insecticides for pest control often leads to environmental pollution and a decrease in biodiversity. Recently, insect sex pheromones were applied for sustainable biocontrol of pests in fields, due to their l…
View article: Effects of Risk Factors for Pregnancy Outcomes of Subsequent Pregnancy Associated with Gestational Diabetes Mellitus: A Retrospective Cohort Study in China.
Effects of Risk Factors for Pregnancy Outcomes of Subsequent Pregnancy Associated with Gestational Diabetes Mellitus: A Retrospective Cohort Study in China. Open
Background Since the implementation of the three‑child policy in China, the number of high-risk pregnant women has increased, causing serious challenges to health care during pregnancy. In this article, we aimed to investigate the impact o…
View article: Recreational Physical Activity, Sitting, and Androgen Metabolism among Postmenopausal Women in the Women's Health Initiative Observational Study
Recreational Physical Activity, Sitting, and Androgen Metabolism among Postmenopausal Women in the Women's Health Initiative Observational Study Open
Background: Prolonged sitting and physical inactivity are associated with higher circulating levels of estrogens. It is unknown whether these risk factors are associated with circulating androgens/androgen metabolites, another set of hormo…
View article: Association of Endogenous Pregnenolone, Progesterone, and Related Metabolites with Risk of Endometrial and Ovarian Cancers in Postmenopausal Women: The B<b>∼</b>FIT Cohort
Association of Endogenous Pregnenolone, Progesterone, and Related Metabolites with Risk of Endometrial and Ovarian Cancers in Postmenopausal Women: The B<b>∼</b>FIT Cohort Open
Background: Postmenopausal pregnenolone and/or progesterone levels in relation to endometrial and ovarian cancer risks have been infrequently evaluated. To address this, we utilized a sensitive and reliable assay to quantify prediagnostic …
View article: Obesity, Height, and Serum Androgen Metabolism among Postmenopausal Women in the Women's Health Initiative Observational Study
Obesity, Height, and Serum Androgen Metabolism among Postmenopausal Women in the Women's Health Initiative Observational Study Open
Background: Anthropometric measures, including obesity, are important risk factors for breast and endometrial cancers in postmenopausal women. It is unknown whether these risk factors are associated with androgen metabolism, another risk f…
View article: Chlamydia trachomatis infection in the genital tract is associated with inflammation and hypospermia in the infertile male of China
Chlamydia trachomatis infection in the genital tract is associated with inflammation and hypospermia in the infertile male of China Open
Chlamydia trachomatis (CT) infection is the most prevalent sexually transmitted bacterial disease worldwide. However, unlike that in female infertility, the role of CT infection in male infertility remains controversial. The objective of t…
View article: 非手性-手性色谱-预测多反应监测法分析中药毛前胡的化学成分
非手性-手性色谱-预测多反应监测法分析中药毛前胡的化学成分 Open
Ligustici Radix (Chinese name: maoqianhu) consists of the dried roots of Ligusticum brachylobum Franch., which is mainly distributed in the Yunnan and Sichuan provinces. This herbal medicine has been primarily used for the treatment…
View article: Evaluation of Prognostic Factors for Clinical Pregnancy Rate Following Artificial Insemination by Husband in the Chinese Population
Evaluation of Prognostic Factors for Clinical Pregnancy Rate Following Artificial Insemination by Husband in the Chinese Population Open
Background: To determine the independent prognostic factors and develop a multivariate logistic regression model for predicting successful pregnancy following artificial insemination by husband (AIH) in infertile Chinese couples. Methods: …