Xiaolei He
YOU?
Author Swipe
View article: Plasma Proteome-Driven Liquid Biopsy for Individualized Monitoring and Risk Stratification of Immune-Related Adverse Events in Checkpoint Immunotherapy
Plasma Proteome-Driven Liquid Biopsy for Individualized Monitoring and Risk Stratification of Immune-Related Adverse Events in Checkpoint Immunotherapy Open
Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy, however, their use is limited by heterogeneous and unpredictable immune-related adverse events (irAEs), which can progress to life-threatening conditions requiring int…
View article: Experimental Investigation on the Bending Performance of Steel–Concrete Composite Beams After Creep
Experimental Investigation on the Bending Performance of Steel–Concrete Composite Beams After Creep Open
The long-term flexural performance of steel-concrete composite beams after creep is influenced by multiple factors such as the degree of shear connection, cross-sectional form, and boundary conditions. The engineering community has an ambi…
View article: ZeroCard: Cardinality Estimation with Zero Dependence on Target Databases -- No Data, No Query, No Retraining
ZeroCard: Cardinality Estimation with Zero Dependence on Target Databases -- No Data, No Query, No Retraining Open
Cardinality estimation is a fundamental task in database systems and plays a critical role in query optimization. Despite significant advances in learning-based cardinality estimation methods, most existing approaches remain difficult to g…
View article: Drug-coated balloon angioplasty versus conventional angioplasty for symptomatic non-acute intracranial artery occlusion
Drug-coated balloon angioplasty versus conventional angioplasty for symptomatic non-acute intracranial artery occlusion Open
Background and objective Non-acute intracranial artery occlusion (ICAO) is an important cause of recurrent ischemic stroke despite aggressive medical treatment. Conventional angioplasty has high incidences of perioperative complications an…
View article: Uterine Microbiota Composition in Dairy Cows with Different Vaginal Discharge Scores: Suggesting Caviibacter as a Potential Pathogen in Mild Purulent Metritis
Uterine Microbiota Composition in Dairy Cows with Different Vaginal Discharge Scores: Suggesting Caviibacter as a Potential Pathogen in Mild Purulent Metritis Open
The uterine microbiota plays a crucial role in maintaining postpartum reproductive health in dairy cows, and its dysregulation is closely associated with uterine diseases. Vaginal discharge characteristics serve as important clinical indic…
View article: Assessing systemic importance using multilayer dynamic networks: Evidence from China's stock market
Assessing systemic importance using multilayer dynamic networks: Evidence from China's stock market Open
International audience
View article: Control strategy for connected automated vehicles to reduce car-following risks and energy consumption on foggy highway
Control strategy for connected automated vehicles to reduce car-following risks and energy consumption on foggy highway Open
The foggy environment negatively affects car-following behavior, increasing rear-end collisions and energy consumption (including fuel consumption and traffic emissions). With advancements in technologies, connected automated vehicles (CAV…
View article: Redox Activity of APE1 Mediates SASP Suppression in Senescent Fibroblasts
Redox Activity of APE1 Mediates SASP Suppression in Senescent Fibroblasts Open
Cellular senescence, triggered by multiple stressors, was characterized by senescence-associated secretory phenotype (SASP) that drive age-related pathologies. Apurinic apyrimidinic endonuclease 1 (APE1), a bifunctional enzyme with redox a…
View article: Risk factors of restenosis after paclitaxel-coated balloon treatment in symptomatic intracranial atherosclerotic disease
Risk factors of restenosis after paclitaxel-coated balloon treatment in symptomatic intracranial atherosclerotic disease Open
Paclitaxel-coated balloon (PCB) treatment has shown promise for intracranial atherosclerotic disease (ICAD). However, studies on restenosis and its associated factors after PCB use are lacking. This study aimed to elucidate risk factors of…
View article: TDMPBC: Self-Imitative Reinforcement Learning for Humanoid Robot Control
TDMPBC: Self-Imitative Reinforcement Learning for Humanoid Robot Control Open
Complex high-dimensional spaces with high Degree-of-Freedom and complicated action spaces, such as humanoid robots equipped with dexterous hands, pose significant challenges for reinforcement learning (RL) algorithms, which need to wisely …
View article: Performance Analysis and Novel Cross-Flow Scheme of Low-Temperature Multi-Effect Distillation for Treating High-Mineralized Mine Water
Performance Analysis and Novel Cross-Flow Scheme of Low-Temperature Multi-Effect Distillation for Treating High-Mineralized Mine Water Open
Low-temperature multi-effect distillation (LT-MED) can be used to desalinate and demineralize highly mineralized mine water, facilitating the recycling and reuse of water resources. This study conducted a simulation of LT-MED technology fo…
View article: Associations between different triglyceride glucose index-related obesity indices and eating disorders: results from NHANES 2005–2018
Associations between different triglyceride glucose index-related obesity indices and eating disorders: results from NHANES 2005–2018 Open
Background This research aimed to determine the possible links between obesity measures related to the triglyceride glucose (TyG) index and the prevalence of eating disorders (ED) for the United States residents. Methods This observational…
View article: Genetic evaluation of iodent hard kernel maize inbred lines
Genetic evaluation of iodent hard kernel maize inbred lines Open
In the present study, 12 introduced Iodent hard kernel maize inbred lines were used as test materials, and four backbone maize inbred lines (JM005, JM006, JF003 and JF004) selected by the present team were tested. NC II genetic mating desi…
View article: Research progress on chemical composition, microbial diversity and effects on human health of koumiss
Research progress on chemical composition, microbial diversity and effects on human health of koumiss Open
Koumiss is an acidic dairy beverage made from the raw milk of mares fermented by lactic acid bacteria and yeast, exhibiting country- and region-dependent differences. Koumiss development history dates back over a thousand years and this be…
View article: Preparation of Value-added Chemicals via Chemical Looping Pyrolysis of Corn Straws with Ca-Fe Composite Oxygen Carrier
Preparation of Value-added Chemicals via Chemical Looping Pyrolysis of Corn Straws with Ca-Fe Composite Oxygen Carrier Open
Biomass chemical looping pyrolysis (BCLPy), which utilizes either reduced or oxidized oxygen carriers for biomass pyrolysis, enables the simultaneous production of high-quality bio-oils and clean syngas. In this study, CLPy of corn straws …
View article: JAK-STAT Domain Enhanced MUC1-CAR-T Cells Induced Esophageal Cancer Elimination [Retraction]
JAK-STAT Domain Enhanced MUC1-CAR-T Cells Induced Esophageal Cancer Elimination [Retraction] Open
[This retracts the article DOI: 10.2147/CMAR.S264358.].
View article: Navigating the Biogeography of Short-forests in Global Drylands
Navigating the Biogeography of Short-forests in Global Drylands Open
The canopy height is pivotal in sustaining carbon cycling and upholding the ecological and biodiversity functions, which is also true or particularly the case for dryland ecosystems. Meanwhile, restorations in drylands have seen massive sh…
View article: Robust JPEG Steganography Based on the Robustness Classifier
Robust JPEG Steganography Based on the Robustness Classifier Open
The application of image steganography in popular image-sharing social networks requires robustness because the JPEG recompression in social networks changes the DCT coefficients of uploaded images. Currently, most robust steganography alg…
View article: Swertia bimaculata moderated liver damage in mice by regulating intestine microbiota
Swertia bimaculata moderated liver damage in mice by regulating intestine microbiota Open
Swertia bimaculata (SB) is a medicinal herb in China having an array of therapeutic and biological properties. This study aimed to explore the attenuating effect of SB on carbon tetrachloride (CCl4) induced hepato-toxicity by regulation of…
View article: Errorless Robust JPEG Steganography Using Steganographic Polar Codes
Errorless Robust JPEG Steganography Using Steganographic Polar Codes Open
Recently, a robust steganographic algorithm that achieves errorless robustness against JPEG recompression is proposed. The method evaluates the behavior of DCT coefficients after recompression using the local JPEG encoder to select robust …
View article: Treatment of flue gas desulfurization wastewater by a coupled precipitation-ultrafiltration process
Treatment of flue gas desulfurization wastewater by a coupled precipitation-ultrafiltration process Open
Flue gas desulfurization (FGD) wastewater is characterized by low pH, high content of hardness ions and COD. In this work, chemical precipitation and ultrafiltration (UF) membrane separation were corporately coupled to treat the FGD wastew…
View article: Design of the Oral English Teaching Method Based on Multimodal Feature Fusion
Design of the Oral English Teaching Method Based on Multimodal Feature Fusion Open
In order to solve the problems of too complex speech extraction algorithm and insufficient representation ability in oral English teaching, this paper proposes a speech scoring mechanism based on multimodal fusion. Firstly, feature extract…
View article: Precise Modeling of Thermal and Strain Rate Effect on the Hardening Behavior of SiC/Al Composite
Precise Modeling of Thermal and Strain Rate Effect on the Hardening Behavior of SiC/Al Composite Open
Temperature and strain rate have significant effects on the mechanical behavior of SiC/Al 2009 composites. This research aimed to precisely model the thermal and strain rate effect on the strain hardening behavior of SiC/Al composite using…
View article: Effects of Strength and Distribution of SiC on the Mechanical Properties of SiCp/Al Composites
Effects of Strength and Distribution of SiC on the Mechanical Properties of SiCp/Al Composites Open
In this paper, considering the strength and geometric discrete distribution characteristics of composite reinforcement, by introducing the discrete distribution function of reinforcement, the secondary development of ABAQUS is realized by …
View article: circAMOTL1L Suppresses Renal Cell Carcinoma Growth by Modulating the miR‐92a‐2‐5p/KLLN Pathway
circAMOTL1L Suppresses Renal Cell Carcinoma Growth by Modulating the miR‐92a‐2‐5p/KLLN Pathway Open
Accumulating evidence indicates that the dysregulation of circular RNAs (circRNAs) contributes to tumor progression; however, the regulatory functions of circRNAs in renal cell carcinoma (RCC) remain largely unknown. In this study, the fun…