Xinjie Wang
YOU?
Author Swipe
View article: Adipose-derived stem cell exosomes: emerging roles and therapeutic application
Adipose-derived stem cell exosomes: emerging roles and therapeutic application Open
Stem cell-derived exosomes have broad application prospects in different medical fields, and are increasingly being considered a replacement for Mesenchymal stromal cells (MSCs) therapy. Adipose-derived stem cells (ADSCs) are an efficient …
View article: Global, regional, and national burdens of five main digestive system cancers in adolescents and young adults from 1990 to 2021 based on the Global Burden of Disease Study 2021: A cross-sectional study
Global, regional, and national burdens of five main digestive system cancers in adolescents and young adults from 1990 to 2021 based on the Global Burden of Disease Study 2021: A cross-sectional study Open
Objective To evaluate the burden and trends of digestive system cancers in adolescents and young adults (AYAs) globally between 1990 and 2021. Methods Data were extracted from the Global Burden of Diseases, Injuries, and Risk Factors Study…
View article: Development of a rapid on-site detection method for largemouth bass virus based on RPA-CRISPR/Cas12a system
Development of a rapid on-site detection method for largemouth bass virus based on RPA-CRISPR/Cas12a system Open
Introduction Largemouth bass virus (LMBV), the causative agent of largemouth bass ulcerative syndrome, poses a significant economic threat to the aquaculture industry. Rapid, simple, and reliable detection methods are essential for the tim…
View article: Immune checkpoint inhibitor-associated myocarditis: a historical and comprehensive review
Immune checkpoint inhibitor-associated myocarditis: a historical and comprehensive review Open
The most fatal side effect associated with revolutionary immune checkpoint inhibitor (ICI) cancer therapies is myocarditis, a rare and devastating complication with a mortality rate approaching 40%. This review comprehensively examines the…
View article: Development of a Rapid On-Site Detection Method for Largemouth Bass Virus Based on Rpa-Crispr/Cas12a System
Development of a Rapid On-Site Detection Method for Largemouth Bass Virus Based on Rpa-Crispr/Cas12a System Open
View article: Modeling immune checkpoint inhibitor associated myocarditis in vitro and its therapeutic implications
Modeling immune checkpoint inhibitor associated myocarditis in vitro and its therapeutic implications Open
View article: Efficacy and safety of low-dose tetracycline, amoxicillin quadruple therapy in <i>Helicobacter pylori</i> infection: A retrospective single center study
Efficacy and safety of low-dose tetracycline, amoxicillin quadruple therapy in <i>Helicobacter pylori</i> infection: A retrospective single center study Open
BACKGROUND Helicobacter pylori (H. pylori ) eradication rates have declined with the rise of antibiotic-resistant strains in recent years. Although highly effective with a low prevalence of resistance, standard dose tetracycline is associa…
View article: Which technique provides more benefits in return to sports and clinical outcomes after anterior cruciate ligament reconstruction: Double-bundle or single-bundle? A randomized controlled study
Which technique provides more benefits in return to sports and clinical outcomes after anterior cruciate ligament reconstruction: Double-bundle or single-bundle? A randomized controlled study Open
Background: The achievement of an optimal return to sport (RTS) has remained a key goal after sports-related injuries, with the ongoing debate on the effectiveness of different surgical approaches for anterior cruciate ligament (ACL) ruptu…
View article: Letter to the Editor Regarding “Clinical and Sonographic Evaluation of the Effectiveness of Extracorporeal Shock Wave Therapy in Patients with Lateral Epicondylitis”
Letter to the Editor Regarding “Clinical and Sonographic Evaluation of the Effectiveness of Extracorporeal Shock Wave Therapy in Patients with Lateral Epicondylitis” Open
1 entitled "Clinical and Sonographic Evaluation of the Effectiveness of Extracorporeal Shock Wave Therapy in Patients with Lateral Epicondylitis".They conducted a clinical trial designed to evaluate and compare the clinical and sonographic…
View article: Deep learning enhancing guide RNA design for CRISPR/Cas12a‐based diagnostics
Deep learning enhancing guide RNA design for CRISPR/Cas12a‐based diagnostics Open
Rapid and accurate diagnostic tests are fundamental for improving patient outcomes and combating infectious diseases. The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) Cas12a‐based detection system has emerged as a pro…
View article: CoHIT: a one-pot ultrasensitive ERA-CRISPR system for detecting multiple same-site indels
CoHIT: a one-pot ultrasensitive ERA-CRISPR system for detecting multiple same-site indels Open
Genetic testing is crucial for precision cancer medicine. However, detecting multiple same-site insertions or deletions (indels) is challenging. Here, we introduce CoHIT (Cas12a-based One-for-all High-speed Isothermal Test), a one-pot CRIS…
View article: Letter to the Editor regarding “The role of nutritional supplement on post-stroke fatigue: A pilot randomized controlled trial”
Letter to the Editor regarding “The role of nutritional supplement on post-stroke fatigue: A pilot randomized controlled trial” Open
View article: Rapid on-site genotyping of the ovine prolific FecB mutation using a CRISPR/Cas12a-based detection system
Rapid on-site genotyping of the ovine prolific FecB mutation using a CRISPR/Cas12a-based detection system Open
BMPR1B is a pivotal gene that influences reproductive performance in sheep. The sheep populations that carry the FecBB mutation within this gene exhibit significantly higher lambing rates compared to wild-type populations. Therefore, scree…
View article: SETD2 as an epigenetic sentinel of transcriptional fidelity in cardiomyocytes: a mechanistic link to heart failure
SETD2 as an epigenetic sentinel of transcriptional fidelity in cardiomyocytes: a mechanistic link to heart failure Open
Epigenetic modulations are pivotal in heart disease progression, yet the specific influence of epigenetic alterations on transcription initiation and elongation in heart failure (HF) is poorly understood. This study focuses on the SETD2-H3…
View article: Two nanobody-based immunoassays to differentiate antibodies against genotype 1 and 2 porcine reproductive and respiratory syndrome virus
Two nanobody-based immunoassays to differentiate antibodies against genotype 1 and 2 porcine reproductive and respiratory syndrome virus Open
Porcine reproductive and respiratory syndrome virus (PRRSV) infection causes significant economic loss to the global pig industry. Genotype 1 and 2 PRRSV (PRRSV-1 and -2) infections have been reported in China, Europe and America. For accu…
View article: A CRISPR/Cas12a-based platform for rapid on-site bovine viral diarrhea virus diagnostics
A CRISPR/Cas12a-based platform for rapid on-site bovine viral diarrhea virus diagnostics Open
View article: A sensitive one-pot ROA assay for rapid miRNA detection
A sensitive one-pot ROA assay for rapid miRNA detection Open
MicroRNAs (miRNAs) and short RNA fragments (18–25 nt) are crucial biomarkers in biological research and disease diagnostics. However, their accurate and rapid detection remains a challenge, largely due to their low abundance, short length,…
View article: The association between vitamin E intake, vitamin D intake and colorectal cancer: evidence from NHANES 2007–2018
The association between vitamin E intake, vitamin D intake and colorectal cancer: evidence from NHANES 2007–2018 Open
Background: We aimed to investigate the relationship between dietary and supplemental intake of vitamin E and vitamin D and colorectal cancer (CRC) using the National Health and Nutrition Examination Survey (NHANES) data from 2007 to 2018 …
View article: The association between Helicobacter pylori infection and pancreatic diseases: a Mendelian Randomization study
The association between Helicobacter pylori infection and pancreatic diseases: a Mendelian Randomization study Open
Object: The relationship between Helicobacter pylori and pancreatic diseases remains a subject of controversy. Our study aims to investigate the association between Helicobacter pylori infection and pancreatic cancer as well as pancreatiti…
View article: Palm Multidiagnostic of <i>Mycoplasma pneumoniae</i>, <i>Chlamydia pneumoniae</i>, <i>Haemophilus influenzae</i>, and <i>Streptococcus pneumoniae</i> Using One‐Tube CRISPR/Cas12a
Palm Multidiagnostic of <i>Mycoplasma pneumoniae</i>, <i>Chlamydia pneumoniae</i>, <i>Haemophilus influenzae</i>, and <i>Streptococcus pneumoniae</i> Using One‐Tube CRISPR/Cas12a Open
The recent high incidence of Mycoplasma pneumoniae (Mp) infections has raised widespread public health concerns. Therefore, rapid and accurate diagnosis of respiratory pathogenic microbial infections is of paramount importance to provide c…
View article: Correction: Fructose‑bisphosphatase1 (FBP1) alleviates experimental osteoarthritis by regulating Protein crumbs homolog 3 (CRB3)
Correction: Fructose‑bisphosphatase1 (FBP1) alleviates experimental osteoarthritis by regulating Protein crumbs homolog 3 (CRB3) Open
View article: A nanobody inhibiting porcine reproductive and respiratory syndrome virus replication via blocking self-interaction of viral nucleocapsid protein
A nanobody inhibiting porcine reproductive and respiratory syndrome virus replication via blocking self-interaction of viral nucleocapsid protein Open
Porcine reproductive and respiratory syndrome (PRRS) is a serious global pig industry disease. Understanding the mechanism of viral replication and developing efficient antiviral strategies are necessary for combating with PRRS virus (PRRS…
View article: Fructose-bisphosphatase1 (FBP1) alleviates experimental osteoarthritis by regulating Protein crumbs homolog 3 (CRB3)
Fructose-bisphosphatase1 (FBP1) alleviates experimental osteoarthritis by regulating Protein crumbs homolog 3 (CRB3) Open
View article: Intra-articular Histone Deacetylase Inhibitor Microcarrier Delivery to Reduce Osteoarthritis
Intra-articular Histone Deacetylase Inhibitor Microcarrier Delivery to Reduce Osteoarthritis Open
The histone deacetylase inhibitor (HDACi) was a milestone in the treatment of refractory T-cell lymphoma. However, the beneficial effects of HDACi have not been appreciated in osteoarthritis (OA). Herein, we implemented a microcarrier syst…
View article: Can Platelets/Mean Platelet Volume Accurately Diagnose Periprosthetic Joint Infection? Revealing Their Actual Diagnostic Efficacy
Can Platelets/Mean Platelet Volume Accurately Diagnose Periprosthetic Joint Infection? Revealing Their Actual Diagnostic Efficacy Open
Compared with traditional biomarkers ESR and CRP, the value of the PMR for diagnosing PJI is not significant, but it can be used as an auxiliary indicator for PJI diagnosis in combination with other indicators (P<0.001).
View article: Customized Trajectory Optimization and Compliant Tracking Control for Passive Upper Limb Rehabilitation
Customized Trajectory Optimization and Compliant Tracking Control for Passive Upper Limb Rehabilitation Open
Passive rehabilitation training in the early poststroke period can promote the reshaping of the nervous system. The trajectory should integrate the physicians’ experience and the patient’s characteristics. And the training should have high…
View article: Efficacy and safety of modified tetracycline dosing in a quadruple therapy for <i>Helicobacter pylori</i>: A retrospective single center study
Efficacy and safety of modified tetracycline dosing in a quadruple therapy for <i>Helicobacter pylori</i>: A retrospective single center study Open
In a real-world experience, modified tetracycline dosing as part of tetracycline and furazolidone quadruple therapy for 14 d demonstrated high efficacy, comparable to standard tetracycline dose regimens, with a favorable safety profile.
View article: Advances of endoscopic and surgical management in gastrointestinal stromal tumors
Advances of endoscopic and surgical management in gastrointestinal stromal tumors Open
As one of the most common mesenchymal malignancies in the digestive system, gastrointestinal stromal tumors (GISTs) occur throughout the alimentary tract with diversified oncological characteristics. With the advent of the tyrosine kinase …
View article: The diagnostic value of ratio biomarkers for periprosthetic joint infection
The diagnostic value of ratio biomarkers for periprosthetic joint infection Open
Background The diagnosis of periprosthetic joint infection (PJI) remains challenging. Currently, there is no single test marker for PJI that has an acceptable level of sensitivity. To enhance diagnostic accuracy, ratio or combined tests ha…
View article: Graft Signal and Clinical Outcomes of Single-bundle Anterior Cruciate Ligament Reconstruction and Double-bundle ACLR: The Different Effects Related with Posterior Tibial Slope
Graft Signal and Clinical Outcomes of Single-bundle Anterior Cruciate Ligament Reconstruction and Double-bundle ACLR: The Different Effects Related with Posterior Tibial Slope Open
Background: The effects of single-bundle and double-bundle ACL reconstruction are still controversial and patients with different anatomy may need to choose different surgery. The aim of the study was to assess the relationship between gra…