Xinjun Ren
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View article: Associations between the monocyte‑lymphocyte ratio and age‑related macular degeneration among US adults: evidence from NHANES 2005–2008
Associations between the monocyte‑lymphocyte ratio and age‑related macular degeneration among US adults: evidence from NHANES 2005–2008 Open
Background Previous studies have established an association between age-related macular degeneration (AMD) and chronic systemic inflammation. However, the relationship between AMD and the monocyte-to-lymphocyte ratio (MLR), a novel inflamm…
View article: Aqueous Humor Proteome in RVO-Associated Macular Edema: Analysis during Three Consecutive Conbercept Treatments
Aqueous Humor Proteome in RVO-Associated Macular Edema: Analysis during Three Consecutive Conbercept Treatments Open
This exploratory proteomic analysis identified distinct pathway alterations in early RVO pathogenesismetabolic in BRVO and inflammatory in CRVOand common treatment-related changes: plasma kallikrein was downregulated, while desmocollin-3…
View article: Efficacy of Intravitreal Conbercept in Vitrectomy for Proliferative Diabetic Retinopathy: An Integrated Meta-Analysis and Bibliometric Study
Efficacy of Intravitreal Conbercept in Vitrectomy for Proliferative Diabetic Retinopathy: An Integrated Meta-Analysis and Bibliometric Study Open
This systematic review revealed that, similarly to other anti-VEGF injections, Conbercept injection improved BCVA and had lower rates of intraoperative and postoperative complications. Conbercept research shows strong global collaboration …
View article: Construction and validation of a neovascular glaucoma nomogram in patients with diabetic retinopathy after pars plana vitrectomy
Construction and validation of a neovascular glaucoma nomogram in patients with diabetic retinopathy after pars plana vitrectomy Open
BACKGROUND Neovascular glaucoma (NVG) is likely to occur after pars plana vitrectomy (PPV) for diabetic retinopathy (DR) in some patients, thus reducing the expected benefit. Understanding the risk factors for NVG occurrence and building e…
View article: Deep learning-based postoperative visual acuity prediction in idiopathic epiretinal membrane
Deep learning-based postoperative visual acuity prediction in idiopathic epiretinal membrane Open
Background To develop a deep learning (DL) model based on preoperative optical coherence tomography (OCT) training to automatically predict the 6-month postoperative visual outcomes in patients with idiopathic epiretinal membrane (iERM). M…
View article: Probable Treatment Targets for Diabetic Retinopathy Based on an Integrated Proteomic and Genomic Analysis
Probable Treatment Targets for Diabetic Retinopathy Based on an Integrated Proteomic and Genomic Analysis Open
Our study suggests possible drugs for DR treatment based on an integrated proteomics and genomics pipeline. This approach can potentially expedite the drug discovery process by identifying already-approved drugs that might be used for new …
View article: Effect of small extracellular vesicles derived from IL-10-overexpressing mesenchymal stem cells on experimental autoimmune uveitis
Effect of small extracellular vesicles derived from IL-10-overexpressing mesenchymal stem cells on experimental autoimmune uveitis Open
Background Autoimmune uveitis is a sight-threatening intraocular inflammation mainly caused by immune dysregulation. The development of safe and effective therapeutic approaches is urgently needed. Small extracellular vesicles (sEVs) deriv…
View article: Application and observation of artificial intelligence in clinical practice of fundus screening for diabetic retinopathy with non-mydriatic fundus photography: a retrospective observational study of T2DM patients in Tianjin, China
Application and observation of artificial intelligence in clinical practice of fundus screening for diabetic retinopathy with non-mydriatic fundus photography: a retrospective observational study of T2DM patients in Tianjin, China Open
Objective: To observe the consistency of a preliminary report of artificial intelligence (AI) in the clinical practice of fundus screening for diabetic retinopathy (DR) using non-mydriatic fundus photography. Methods: Patients who underwen…
View article: Human umbilical cord-derived mesenchymal stem cells treatment for refractory uveitis: a case series
Human umbilical cord-derived mesenchymal stem cells treatment for refractory uveitis: a case series Open
AIM: To evaluate therapeutic outcomes of human umbilical cord-derived mesenchymal stem cells (HUC-MSCs) treatment in patients with refractory uveitis. METHODS: A retrospective and noncomparative review was performed on four patients with r…
View article: Utilizing dexamethasone intravitreal implant to control postoperative inflammation in refractory uveitis undergoing cataract surgery
Utilizing dexamethasone intravitreal implant to control postoperative inflammation in refractory uveitis undergoing cataract surgery Open
AIM: To report the effectiveness of intravitreal implantation of dexamethasone implant (Ozurdex) after phacoemulsification and intraocular lens implantation in refractory uveitis patients. METHODS: This single-center retrospective study co…
View article: Clinical experience of using the NGENUITY three‐dimensional surgery system in ophthalmic surgical procedures
Clinical experience of using the NGENUITY three‐dimensional surgery system in ophthalmic surgical procedures Open
Purpose To assess the clinical experience of using a three‐dimensional (3D) system for ophthalmic surgical procedures. Methods We retrospectively analysed video recordings of patients who underwent 3D ophthalmic surgery, using the NGENUITY…
View article: Comparison of visual quality in cataract patients with low astigmatism after ART2 or ReSTOR intraocular lens implantation
Comparison of visual quality in cataract patients with low astigmatism after ART2 or ReSTOR intraocular lens implantation Open
ART2 is more suitable than ReSTOR for cataract patients with regular corneal astigmatism 0.75-1.0 D with-the-rule or 0.5-0.75 D against-the-rule.
View article: Dexamethasone intravitreous implant vs bevacizumab for central retinal vein occlusion‐related macular oedema: A prospective randomized comparison—Comment
Dexamethasone intravitreous implant vs bevacizumab for central retinal vein occlusion‐related macular oedema: A prospective randomized comparison—Comment Open
We read with great interest the randomized controlled trial by Gado and Macky, presenting the outcomes of patients with central vein occlusion treated with Bevacizumab or dexamethasone implant.1 Best corrected visual acuity (BCVA) of candi…