Xiaowen Yan
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View article: Site-Specific Conjugated Antibody-Element Tags for Single-Cell ICP-MS
Site-Specific Conjugated Antibody-Element Tags for Single-Cell ICP-MS Open
View article: Engineering heavy chain antibody‐drug conjugates against solid tumors for a one‐shot kill
Engineering heavy chain antibody‐drug conjugates against solid tumors for a one‐shot kill Open
View article: Covalent Targeting Drug Mediated Specific Lanthanide Tagging Towards In Situ Bruton's Tyrosine Kinase Quantification Using ICP-MS
Covalent Targeting Drug Mediated Specific Lanthanide Tagging Towards In Situ Bruton's Tyrosine Kinase Quantification Using ICP-MS Open
Bruton's tyrosine kinase (BTK) is an important target for the treatment of multiple B-cell malignancies and autoimmune diseases.Development of approach that can accurately detect the expression and activity of BTK in live cells is of great…
View article: Changes in fruit texture and cell structure of different pumpkin varieties (lines) during storage
Changes in fruit texture and cell structure of different pumpkin varieties (lines) during storage Open
After harvest, the pumpkin fruit has strong respiration and metabolic activities, which easily induce quality deterioration, shortening the storage period and shelf life, which affects the farmers' income. To understand the quality change …
View article: Safety of high-carbohydrate fluid diet 2 h versus overnight fasting before non-emergency endoscopic retrograde cholangiopancreatography: A single-blind, multicenter, randomized controlled trial
Safety of high-carbohydrate fluid diet 2 h versus overnight fasting before non-emergency endoscopic retrograde cholangiopancreatography: A single-blind, multicenter, randomized controlled trial Open
Background: Although overnight fasting is recommended prior to endoscopic retrograde cholangiopancreatography (ERCP), the benefits and safety of high-carbohydrate fluid diet (CFD) intake 2 h before ERCP remain unclear. This study aimed to …
View article: Influence of Different Device Structures on the Degradation for Trench-Gate SiC MOSFETs: Taking Avalanche Stress as an Example
Influence of Different Device Structures on the Degradation for Trench-Gate SiC MOSFETs: Taking Avalanche Stress as an Example Open
The variations in the degradation of electrical characteristics resulting from different device structures for trench-gate SiC metal-oxide-semiconductor field effect transistors (MOSFETs) are investigated in this work. Two types of the mos…
View article: Single-cell fucosylation breakdown: Switching fucose to europium
Single-cell fucosylation breakdown: Switching fucose to europium Open
View article: Single-Cell Fucosylation Breakdown: Switching Fucose to Europium
Single-Cell Fucosylation Breakdown: Switching Fucose to Europium Open
View article: Polycomb repressive 2 complex—Molecular mechanisms of function
Polycomb repressive 2 complex—Molecular mechanisms of function Open
Numerous molecular processes conduct epigenetic regulation of protein transcription to maintain cell specification. In this review, we discuss molecular mechanisms of the Polycomb group of proteins and its enzymatic role in epigenetics. Mo…
View article: P1DH.1 - A Sensitive Amperometric Immunosensor Based on AuNPs-TiO2-graphene Nanocomposites for the Detection of Carcinoembryonic Antigen
P1DH.1 - A Sensitive Amperometric Immunosensor Based on AuNPs-TiO2-graphene Nanocomposites for the Detection of Carcinoembryonic Antigen Open
A novel and sensitive sandwiched amperometric immunosensor was fabricated which mainly took advantage of AuNPs-TiO 2 -graphene nanocomposites as immobilizing enzyme-labeled antibody for the detection of carcino-embryonic antigen (CEA).By s…
View article: Quantitative synthesis of protein–DNA conjugates with 1 : 1 stoichiometry
Quantitative synthesis of protein–DNA conjugates with 1 : 1 stoichiometry Open
We describe here a binding-facilitated reaction strategy, enabling quantitative conjugation of DNA to native proteins with a desirable 1 : 1 stoichiometry.
View article: Modulation of mitogen-activated protein kinase attenuates sepsis-induced acute lung injury in acute respiratory distress syndrome rats
Modulation of mitogen-activated protein kinase attenuates sepsis-induced acute lung injury in acute respiratory distress syndrome rats Open
Sepsis is the most important predisposing cause inducing acute respiratory distress syndrome (ARDS); however, the mechanism of sepsis leading to the development of ARDS remains to be elucidated. Suppression of the mitogen‑activated protein…