Xinnian Chen
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View article: Investigating dimensions of instructor trust using the words of undergraduate STEM students
Investigating dimensions of instructor trust using the words of undergraduate STEM students Open
Introduction Recent work has shown that student trust in their instructor is a key moderator of STEM student buy-in to evidence-based teaching practices (EBTs), enhancing positive student outcomes such as performance, engagement, and persi…
View article: Effectiveness and Safety of Locoregional Combined with Systemic Therapies for Unresectable Hepatocellular Carcinoma: a Bayesian Network Meta-analysis
Effectiveness and Safety of Locoregional Combined with Systemic Therapies for Unresectable Hepatocellular Carcinoma: a Bayesian Network Meta-analysis Open
Review question / Objective: This study aimed to assess the clinical efficacy and safety of locoregional therapy in combination with systemic therapy for unresectable hepatocellular carcinoma by a Bayesian Network Meta-analysis.Participant…
View article: Physiology labs during a pandemic: What did we learn?
Physiology labs during a pandemic: What did we learn? Open
This article captures a collective reflection on the successes and challenges we experienced when teaching physiology laboratories online during the COVID-19 pandemic. Physiology instructors from six institutions discussed their own effort…
View article: A Framework of College Student Buy-in to Evidence-Based Teaching Practices in STEM: The Roles of Trust and Growth Mindset
A Framework of College Student Buy-in to Evidence-Based Teaching Practices in STEM: The Roles of Trust and Growth Mindset Open
This investigation tests a college science, technology, engineering, and mathematics (STEM) student buy-in framework and contributes to understanding the social and cognitive factors influencing students in evidence-based teaching contexts…
View article: Using Pathway Modeling to Evaluate and Improve Student-Centered Teaching Practices in Co-Taught College Science Courses
Using Pathway Modeling to Evaluate and Improve Student-Centered Teaching Practices in Co-Taught College Science Courses Open
This Essay demonstrates how course pathway modeling can help co-instructors better represent the complexity of student-centered teaching practices. It discusses how this approach can improve curricular design, course evaluation, student as…
View article: Using Pathway Modeling to Evaluation and Improve Student-Centered Teaching Practices in Co-Taught College Science Courses
Using Pathway Modeling to Evaluation and Improve Student-Centered Teaching Practices in Co-Taught College Science Courses Open
Student-centered teaching practices such as active learning continue to gain momentum in college science education. Many instructors committed to these innovative practices transform their classroom beyond the standard lecture. Nevertheles…
View article: Isoflurane inhibits a Kir4.1/5.1-like conductance in neonatal rat brainstem astrocytes and recombinant Kir4.1/5.1 channels in a heterologous expression system
Isoflurane inhibits a Kir4.1/5.1-like conductance in neonatal rat brainstem astrocytes and recombinant Kir4.1/5.1 channels in a heterologous expression system Open
An unwanted side effect of isoflurane anesthesia is suppression of breathing. Despite this clinical significance, effects of isoflurane on cellular and molecular elements of respiratory control are not well understood. Here, we show that i…
View article: Benefits of a College STEM Faculty Development Initiative: Instructors Report Increased and Sustained Implementation of Research-Based Instructional Strategies
Benefits of a College STEM Faculty Development Initiative: Instructors Report Increased and Sustained Implementation of Research-Based Instructional Strategies Open
The Summer Institutes on Scientific Teaching (SI) is a faculty development workshop in which science, technology, engineering, and mathematics (STEM) instructors, particularly from biology, are trained in the Scientific Teaching (ST) pedag…
View article: Disordered breathing in a mouse model of Dravet syndrome
Disordered breathing in a mouse model of Dravet syndrome Open
Dravet syndrome (DS) is a form of epilepsy with a high incidence of sudden unexpected death in epilepsy (SUDEP). Respiratory failure is a leading cause of SUDEP, and DS patients’ frequently exhibit disordered breathing. Despite this, mecha…
View article: Author response: Disordered breathing in a mouse model of Dravet syndrome
Author response: Disordered breathing in a mouse model of Dravet syndrome Open
Article Figures and data Abstract Introduction Results Discussion Materials and methods Data availability References Decision letter Author response Article and author information Metrics Abstract Dravet syndrome (DS) is a form of epilepsy…
View article: Risk factors of latent tuberculosis infection and immune function in health care workers in Suzhou, China
Risk factors of latent tuberculosis infection and immune function in health care workers in Suzhou, China Open
This study through rigorous sample collection and analysis found the risk factors of latent tuberculosis infection in health care workers. This finding may provide a theoretical basis to be used by the countries with a high TB burden to fu…
View article: Disordered breathing in a mouse model of Dravet syndrome
Disordered breathing in a mouse model of Dravet syndrome Open
Dravet syndrome (DS) is a form of epilepsy with a high incidence of sudden unexpected death in epilepsy (SUDEP). Respiratory failure is a leading cause of SUDEP, and DS patients’ frequently exhibit disordered breathing. Despite this, mecha…
View article: Trust, Growth Mindset, and Student Commitment to Active Learning in a College Science Course
Trust, Growth Mindset, and Student Commitment to Active Learning in a College Science Course Open
There is growing consensus regarding the effectiveness of active-learning pedagogies in college science courses. Less is known about ways that student-level factors contribute to positive outcomes in these contexts. The present study exami…
View article: Does Context Matter? Convergent and Divergent Findings in the Cross-Institutional Evaluation of Graduate Teaching Assistant Professional Development Programs
Does Context Matter? Convergent and Divergent Findings in the Cross-Institutional Evaluation of Graduate Teaching Assistant Professional Development Programs Open
Graduate teaching assistants (GTAs) play important instructional roles in introductory science courses, yet they often have little training in pedagogy. The most common form of teaching professional development (PD) for GTAs is a presemest…
View article: More significance of <scp>TB</scp>‐<scp>IGRA</scp> except for the diagnose of tuberculosis
More significance of <span>TB</span>‐<span>IGRA</span> except for the diagnose of tuberculosis Open
Objective Tuberculosis ( TB )‐interferon gamma release assay ( IGRA ) test has the characteristics of short time, high specificity, and high sensitivity, but it lacks the correlation research between TB ‐ IGRA test results and body's immun…
View article: New attempt in tuberculosis treatment: autologous cytokine-induced killer after chemotherapy treatment failure in a case of multi-drug resistant tuberculosis (MTB).
New attempt in tuberculosis treatment: autologous cytokine-induced killer after chemotherapy treatment failure in a case of multi-drug resistant tuberculosis (MTB). Open
A 32-year-old woman was diagnosed as pulmonary tuberculosis 15 years ago and recurred several times due to long-term nonstandard treatment. Drug sensitivity test indicated that multidrug-resistant tuberculosis had emerged and we determined…
View article: Student Buy-In to Active Learning in a College Science Course
Student Buy-In to Active Learning in a College Science Course Open
The benefits of introducing active learning in college science courses are well established, yet more needs to be understood about student buy-in to active learning and how that process of buy-in might relate to student outcomes. We test t…