Xinqiang Guan
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View article: Percutaneous closure versus surgical repair for ruptured sinus of valsalva aneurysm: A systematic review and meta-analysis
Percutaneous closure versus surgical repair for ruptured sinus of valsalva aneurysm: A systematic review and meta-analysis Open
Objectives Ruptured sinus of Valsalva aneurysm (RSVA) often has an abrupt onset, and can chest pain, acute heart failure, and even sudden death. The effectiveness of different treatment modalities remains controversial. Thus, we completed …
View article: Engineered elastin-like polypeptides: An efficient platform for enhanced cancer treatment
Engineered elastin-like polypeptides: An efficient platform for enhanced cancer treatment Open
Drug delivery systems (DDSs) have recently gained widespread attention for improving drug loading and delivery efficiency in treating many cancers. Elastin-like polypeptides (ELPs) are synthetic peptides derived from a precursor of elastin…
View article: Use of Novel Blunt Dissection Technique for Surgical Unroofing in Myocardial Bridging Patients
Use of Novel Blunt Dissection Technique for Surgical Unroofing in Myocardial Bridging Patients Open
Background. Myocardial bridging (MB) is a congenital anomaly involving the myocardial tissue encasement of a segment of the coronary artery. The purpose of the present study was to assess safety and efficacy of two surgical methods used fo…
View article: Translational value of partial resection of the pulmonary artery wall for congenital heart disease-induced bronchial compression
Translational value of partial resection of the pulmonary artery wall for congenital heart disease-induced bronchial compression Open
Objective This study was performed to evaluate the clinical efficacy and safety of a novel surgical procedure in treating tracheal or bronchial compression related to severe congenital heart disease. Methods The clinical data of 28 patient…
View article: MicroRNA‑663 participates in myocardial fibrosis through interaction with TGF‑β1
MicroRNA‑663 participates in myocardial fibrosis through interaction with TGF‑β1 Open
MicroRNA-663 (miRNA-663) regulates the expression of transforming growth factor β1 (TGF-β1), which participates in the pathogenesis of myocardial fibrosis. Therefore, microRNA-663 may also serve a role in myocardial fibrosis. The present s…