Xintong Sun
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View article: A cocktail vaccine with monkeypox virus antigens confers protection without selecting mutations in potential immune evasion genes in the vaccinia WR strain challenge
A cocktail vaccine with monkeypox virus antigens confers protection without selecting mutations in potential immune evasion genes in the vaccinia WR strain challenge Open
Faced with the global monkeypox outbreak, current vaccine development predominantly focuses on the mRNA platform despite its limitations in stability and long-term efficacy. Here, we engineered a recombinant vesicular stomatitis virus (rVS…
View article: Identification of plasma cell infiltration-related gene signatures as a novel prognostic model for clear cell renal cell carcinoma
Identification of plasma cell infiltration-related gene signatures as a novel prognostic model for clear cell renal cell carcinoma Open
This study aimed to identify key genes regulating plasma cell (PC) infiltration in kidney renal clear cell carcinoma (KIRC) and construct a novel prognostic model for predicting KIRC. Clear cell renal cell carcinoma is the most common mali…
View article: Guidance of WeChat Applet for Hospitalization Improve Satisfaction and Shorten Preoperative Preparation Time for Advanced Gastric Cancer Patients: A Randomized Clinical Trial (Preprint)
Guidance of WeChat Applet for Hospitalization Improve Satisfaction and Shorten Preoperative Preparation Time for Advanced Gastric Cancer Patients: A Randomized Clinical Trial (Preprint) Open
BACKGROUND The improvement of patient experiences formulates essential for medical service enhancement. Our previous practices have revealed that the utility of the comprehensive hospitalization guidance via WeChat Applet improve satisfac…
View article: Comprehensive analysis of the leukocyte immunoglobulin-like receptor family in clear cell renal cell carcinoma
Comprehensive analysis of the leukocyte immunoglobulin-like receptor family in clear cell renal cell carcinoma Open
These insights establish a foundation for further research into their potential as targets for cancer immunotherapy, improving predictive capabilities and the development of personalized treatments.
View article: Salivary mycobiome alterations in HIV-infected MSM: dominance of Pseudogymnoascus and functional shifts across disease stages
Salivary mycobiome alterations in HIV-infected MSM: dominance of Pseudogymnoascus and functional shifts across disease stages Open
Background Oral health is increasingly recognized as a crucial determinant of overall health in people living with HIV/AIDS (PLWHA). Specifically, the oral mycobiome may play a pivotal role in HIV-associated oral complications. However, th…
View article: DERL3 facilitates the progression of clear cell renal cell carcinoma by promoting epithelial-mesenchymal transition via regulation of the TGFB1 pathway
DERL3 facilitates the progression of clear cell renal cell carcinoma by promoting epithelial-mesenchymal transition via regulation of the TGFB1 pathway Open
Background Clear cell renal cell carcinoma (ccRCC) is a highly prevalent malignancy within the urinary system. The intrinsic heterogeneity and resistance to conventional chemotherapy and radiotherapy contribute to the poor prognosis of adv…
View article: A prognostic signature based on genes associated with m6A/m5C/m1A/m7G modifications and its immunological characteristics in clear cell renal cell carcinoma
A prognostic signature based on genes associated with m6A/m5C/m1A/m7G modifications and its immunological characteristics in clear cell renal cell carcinoma Open
Clear cell renal cell carcinoma (ccRCC) is characterized by a high incidence and mortality rate. Despite advancements in therapeutic interventions, the prognosis for renal cancer patients remains suboptimal. Of late, methylation modificati…
View article: Crosstalk between human immunodeficiency virus infection and salivary bacterial function in men who have sex with men
Crosstalk between human immunodeficiency virus infection and salivary bacterial function in men who have sex with men Open
Background Engaging in anal sexual intercourse markedly increases the risk of developing HIV among men who have sex with men (MSM); oral sexual activities tend to uniquely introduce gut-derived microbes to salivary microbiota, which, combi…
View article: Additional file 1 of Transcriptome analysis of long non-coding RNA and mRNA Profiles in VSV-infected BHK-21 Cells
Additional file 1 of Transcriptome analysis of long non-coding RNA and mRNA Profiles in VSV-infected BHK-21 Cells Open
Additional file 1.
View article: Crosstalk between human immunodeficiency virus infection and salivary bacterial function in men who have sex with men
Crosstalk between human immunodeficiency virus infection and salivary bacterial function in men who have sex with men Open
Background Engaging in anal sexual intercourse markedly increases the risk of developing HIV among men who have sex with men (MSM); oral sexual activities tend to uniquely introduce gut-derived microbes to salivary microbiota, which, combi…
View article: The Underrated Salivary Virome of Men Who Have Sex With Men Infected With HIV
The Underrated Salivary Virome of Men Who Have Sex With Men Infected With HIV Open
Salivary virome is important for oral ecosystem, but there are few reports on people living with HIV. We performed metagenomic sequencing to compare composition and functional genes of salivary virobiota between one HIV-negative and four H…