Explanipedia

Study on the effects and mechanisms of M2 macrophages on PYCR1-promoted biological behavior of hepatocellular carcinoma cells Open

Xinxin Jin, Yachao Hou, Jiayi Guo, Junli Zhang, Wenjuan Wu · 2025

Background Pyrrole-5-carboxylic acid reductase 1 (PYCR1) is a key enzyme involved in proline synthesis and is closely related to the development of hepatocellular carcinoma. This study aimed to investigate the relationship and mechanism be…

Study on the Correlation between TDP-43, HDAC6, Prdx1 Proteins and Brain Oxygen Levels and Cognitive Function in Schizophrenia Open

Ziling Tang, Han Zhang, Yanwen Lin, Ran Hu, Xiaoyue Hu , et al. · 2025

Objective To analyze the expression levels of trans-activation regulatory DNA-binding protein 43 (TDP-43), histone deacetylase 6 (HDAC6), peroxiredoxin 1 (Prdx1), and brain-derived neurotrophic factor (BDNF) in patients with schizophrenia,…

Effect and mechanism of PYCR1 on biological function of hepatocellular carcinoma cells under hypoxia Open

Jiayi Guo, Xinxin Jin, Junli Zhang, Yuming Zhang, Wenjuan Wu · 2025

In summary, we report that hypoxia-mediated PYCR1 promotes proline synthesis in HCC, cell proliferation, inhibits apoptosis, and ultimately promotes tumor progression through the MAPK/ERK/STAT3 signaling pathway, suggesting that PYCR1 is a…

Comprehensive analysis of the critical role of the epithelial mesenchymal transition subtype - TAGLN-positive fibroblasts in colorectal cancer progression and immunosuppression Open

Junli Zhang, Xinxin Jin, Yachao Hou, Biao Gu, Hongwei Li , et al. · 2025

Sliding Effect of Polyrotaxane Enhances Fatigue Resistance of Ionic Gel Open

Ming Song, Xinxin Jin, Deshuo Kong, Guorong Ma, Changxian Wang , et al. · 2025

Tunable multi-wavelength mode-locked thulium-doped fiber laser with precise controlled wavelength spacing via Mach-Zehnder interferometer Open

Qian Zhang, Yuxing Dai, Huizheng Li, Xinxin Jin, Qing Wu · 2025

Parameter adjustable mid-infrared ultra-short pulse-burst laser around 2.94 μm Open

Yongchang Zhang, Bowen Zheng, Xupeng Wang, Xinxin Jin, Zhihong Li , et al. · 2025

We report a parameter adjustable mid-infrared (MIR) ultra-short pulse-burst laser based on the difference frequency generation (DFG) within a periodically poled MgO:LiNbO 3 crystal. A uniform pulse laser at 1.03 μm with a sub-GHz repetitio…

Purity and composite petal-like mode laser emission with tunable topological charge from 1 to 35 Open

朱海永 Zhu Haiyong, Zihan Zhang, Jie Liu, Yongchang Zhang, Xinxin Jin , et al. · 2025

In this work, we demonstrate the generation of low-order petal mode beams with tunable topological charge from a laser system utilizing an axicon based annular pump shaping system. By tuning the shape of the pump beam and axially displacin…

Generation of leaky mode resonance and lossy mode resonance with the same optical platform Open

Zhihong Li, Yongchang Zhang, Xinxin Jin, Feng Liu, Yanmin Duan , et al. · 2024

Leaky mode resonance (L e MR) and lossy mode resonance (L o MR) refer to two different surface waves but are easily confused. Herein, we comprehensively investigated the excitation mechanism and sensing performance of both L e MR and L o M…

The Wettability and High-Temperature Properties of Porous BN/Si3N4 Ceramics Bonded with SiTi22 Filler Open

Yanli Zhuang, Hao Cheng, Xinghuan Wang, Limin Dong, Panpan Lin , et al. · 2024

The wettability and high-temperature mechanical properties of porous BN/Si3N4 ceramics brazed with SiTi22 (wt. %) filler were studied. It is manifested that SiTi22 filler presents remarkable wetting and spreading capabilities on the porous…

Mode-locking dynamics of triple attractors in a wavelength-multiplexing fiber laser Open

Xinxin Jin, Ruiyan Liu, Yongchang Zhang, Zhihong Li, Yanmin Duan , et al. · 2024

We demonstrate the coexistence of triple attractors in a mode-locked ring fiber laser with equal dual-gain-channel. Even under identical cavity conditions, quantum noise can evolve into three distinct stable states: tightly bound soliton, …

Controlled generation of soliton molecules from a dispersion-managed Tm-doped fiber laser with BP-SA Open

Qian Zhang, Xinxin Jin, Meng Zhang, Qing Wu, Zheng Zheng · 2024

We report the experimental observation of soliton molecules in a dispersion-managed thulium-doped (Tm-doped) fiber laser utilizing a black phosphorus saturable absorber (BP-SA). A variety of soliton molecules can be detected with the incre…

Identification of cuproptosis-related long non-coding RNA and construction of a novel prognostic signature for bladder cancer: An observational study Open

Zegen Ye, Chunhua Liu, Simin Wu, Xinxin Jin, Huajian Lin , et al. · 2024

Bladder Urothelial Carcinoma (BLCA), a prevalent and lethal cancer, lacks understanding regarding the roles and prognostic value of cuproptosis-related lncRNAs (CRLs), a novel form of cell death induced by copper. We collected RNA-seq data…

KTA-OPO for 1742 nm laser generation driven by a composite Nd:YVO<sub>4</sub>-based self-Raman laser Open

Yanmin Duan, Jie Liu, Hongyan Wang, Yongchang Zhang, Xinxin Jin , et al. · 2024

In this work, a double-end diffusion bonded Nd:YVO 4 self-Raman laser was designed to drive an intracavity, noncritically-phase-matched KTiOAsO 4 (KTA) optical parametric oscillator (OPO). Both conversion efficiency and output power at 1.7…

Compact and Tunable Mid-Infrared Raman Soliton Source Based on Heavily Geo2-Doped Fiber Open

Qian Zhang, Meng Zhang, Xinxin Jin, Zheng Zheng · 2024

Controlled Generation Of Soliton Molecules from a Dispersion-Managed Tm-Doped Fiber Laser with Bp-Sa Open

Qian Zhang, Xinxin Jin, Meng Zhang, Qing Wu, Zheng Zheng · 2024

An Axicon-Based Annular Pump Acousto-Optic Q-Switched Nd:GdVO4 Self-Raman Vortex Laser Open

Jie Liu, Yanmin Duan, Wenjie Mao, Xinxin Jin, Zhihong Li , et al. · 2023

We report, for the first time, the generation of a 1173 nm acousto-optic Q-switched self-Raman vortex laser with an axicon-based annular pump system. A 20 mm long Nd:GdVO4 crystal was used as the self-Raman crystal. Both the fundamental fi…

Decoupling bulk and surface characteristics with a bare tilted fiber Bragg grating Open

Zhihong Li, Fei Wang, Yanan Wang, Xinxin Jin, Yanmin Duan , et al. · 2023

The tilted fiber Bragg grating (TFBG) with dense comb-like resonances offers a promising fiber-optic sensing platform but could suffer from cross sensitivity dependent on bulk and surface environment. In this work, the decoupling of bulk a…

A Microfluidic Concentration Gradient Colorimetric System for Rapid Detection of Nitrite in Surface Water Open

Man Yan, Kaijia Yu, Tan Hui‐min, Xinxin Jin, Tao Jing , et al. · 2023

Slidable and Highly Ionic Conductive Polymer Binder for High‐Performance Si Anodes in Lithium‐Ion Batteries Open

Yifeng Cai, Caixia Liu, Zhiao Yu, Wencan Ma, Qi Jin , et al. · 2022

Silicon is expected to become the ideal anode material for the next generation of high energy density lithium battery because of its high theoretical capacity (4200 mAh g −1 ). However, for silicon electrodes, the initial coulombic efficie…

Diode-pumped, actively Q-switched Nd,La:CaNb2O6 self-Raman laser at 1,174 nm Open

Youyi Zhuang, Wenjie Mao, Xinghong Gong, Xinxin Jin, Zhihong Li , et al. · 2022

Diode end-pumped Nd,La:CaNb 2 O 6 self-Raman laser with acousto-optic Q-switching was successfully demonstrated for the first Stokes wave generation at 1,174 nm. A 1.0 at.% Nd 3+ and 1.0 at.% La 3+ -doped CaNb 2 O 6 crystal in dimensions 3…

Discrimination of Geographical Origin of Agricultural Products From Small-Scale Districts by Widely Targeted Metabolomics With a Case Study on Pinggu Peach Open

Jie Zhao, An Li, Xinxin Jin, Gang Liang, Ligang Pan · 2022

Geographical indications of agricultural products are characterized by high quality and regional attributes, while they are more likely to be counterfeited by similar products from nearby regions. Accurate discrimination of origin on small…

The Formation Process and Strengthening Mechanism of SiC Nanowires in a Carbon-Coated Porous BN/Si3N4 Ceramic Joint Open

Yanli Zhuang, Tiesong Lin, Peng He, Panpan Lin, Limin Dong , et al. · 2022

Porous BN/Si3N4 ceramics carbon-coated by carbon coating were joined with SiCo38 (wt. %) filler. The formation process and strengthening mechanism of silicon carbide nanowires to the joint were analyzed in detail. The outcome manifests tha…

FeCo-based mesoporous carbon shells modified N-doped porous carbon spheres for oxygen reduction reaction Open

Xinxin Jin, Yan Xie, Chaoyue Zhao, Yinghao Xu, Yang Lv , et al. · 2021

EFFECT OF PORE COMPOSITION ON THERMAL SHOCK RESISTANCE OF POROUS CERAMICS Open

Maochang Cao, Xinxin Jin, Limin Dong, X. Y. LI, X. Y ZHANG · 2021

Porous alumina ceramics with different pore composition (intrinsic pores and extrinsic pores) were prepared by gel injection molding process combined with pore forming technology and effects of intergranular pores and extrinsic pores on th…

Sub-150 fs dispersion-managed soliton generation from an all-fiber Tm-doped laser with BP-SA Open

Qian Zhang, Xinxin Jin, Guohua Hu, Meng Zhang, Zheng Zheng , et al. · 2020

We demonstrate an all-fiber, thulium-doped, mode-locked laser using a black phosphorus (BP) saturable absorber (SA). The BP-SA, exhibiting strong nonlinear response, is fabricated by inkjet printing. The oscillator generates self-starting …

A general ink formulation of 2D crystals for wafer-scale inkjet printing Open

Guohua Hu, Lisong Yang, Zongyin Yang, Yubo Wang, Xinxin Jin , et al. · 2020

A binary solvent ink exploiting solutal Marangoni flows to suppress the coffee-ring effect for uniform printing of 2D crystals.

Additive manufacturing of hydroxyapatite bioceramic scaffolds: Dispersion, digital light processing, sintering, mechanical properties, and biocompatibility Open

Chengwei Feng, Keqiang Zhang, Rujie He, Guojiao Ding, Min Xia , et al. · 2020

Hydroxyapatite (HA) bioceramic scaffolds were fabricated by using digital light processing (DLP) based additive manufacturing. Key issues on the HA bioceramic scaffolds, including dispersion, DLP fabrication, sintering, mechanical properti…

Environmentally stable black phosphorus saturable absorber for ultrafast laser Open

Xinxin Jin, Guohua Hu, Meng Zhang, Tom Albrow‐Owen, Zheng Zheng , et al. · 2020

Black phosphorus (BP) attracts huge interest in photonic and optoelectronic applications ranging from passive switch for ultrafast lasers to photodetectors. However, the instability of chemically unfunctionalized BP in ambient environment …

Broad bandwidth dual-wavelength fiber laser simultaneously delivering stretched pulse and dissipative soliton Open

Xinxin Jin, Meng Zhang, Guohua Hu, Qing Wu, Zheng Zheng , et al. · 2020

We numerically and experimentally demonstrate the generation of broad bandwidth mode-locked dual-wavelength pulses with diverse-pattern from a dispersion managed erbium-doped (Er-doped) fiber laser. The two-peak gain profile of the Er-dope…

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