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View article: Controlled hypotension under rapid ventricular pacing technique in patients with cerebral arteriovenous malformation -a case report-
Controlled hypotension under rapid ventricular pacing technique in patients with cerebral arteriovenous malformation -a case report- Open
Background: The transvenous approach to the treatment of cerebral arteriovenous malformation (AVM) is difficult and requires strict blood pressure and blood flow control; however, the cure rate is very high. Appropriate blood pressure cont…
View article: HSPA12A promotes c-Myc lactylation-mediated proliferation of tubular epithelial cell to facilitate renal functional recovery from kidney ischemia/reperfusion injury
HSPA12A promotes c-Myc lactylation-mediated proliferation of tubular epithelial cell to facilitate renal functional recovery from kidney ischemia/reperfusion injury Open
Proliferation of renal tubular epithelial cells (TEC) is essential to restore tubular integrity and thereby to support renal functional recovery from kidney ischemia/reperfusion (KI/R) injury. The transcriptional factor c-Myc is activated …
View article: Penehyclidine mitigates intraoperative oculocardiac reflex and postoperative nausea and vomiting in the patients with strabismus surgery: a prospective, randomized, double-blinded comparison
Penehyclidine mitigates intraoperative oculocardiac reflex and postoperative nausea and vomiting in the patients with strabismus surgery: a prospective, randomized, double-blinded comparison Open
BackgroundPONV is one of the most frequent complications following anesthesia and strabismus surgery. Penehyclidine, an anticholinergic, is widely and preoperatively used for reducing glandular secretion in patients. This study investigate…
View article: Heat‐Shock protein A12A is a novel PCNA‐binding protein and promotes hepatocellular carcinoma growth
Heat‐Shock protein A12A is a novel PCNA‐binding protein and promotes hepatocellular carcinoma growth Open
Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. Proliferating cell nuclear antigen (PCNA) plays a pivotal role in cancer development and progression. However, the long‐term dismal prognosis of HCC mandates more i…
View article: HSPA12A unstabilizes CD147 to inhibit lactate export and migration in human renal cell carcinoma
HSPA12A unstabilizes CD147 to inhibit lactate export and migration in human renal cell carcinoma Open
Background: Metastasis accounts for 90% of cancer-associated mortality in patients with renal cell carcinoma (RCC). However, the clinical management of RCC metastasis is challenging. Lactate export is known to play an important role in can…
View article: Cardiomyocyte-specific deficiency of HSPB1 worsens cardiac dysfunction by activating NFκB-mediated leucocyte recruitment after myocardial infarction
Cardiomyocyte-specific deficiency of HSPB1 worsens cardiac dysfunction by activating NFκB-mediated leucocyte recruitment after myocardial infarction Open
Aims Inadequate healing after myocardial infarction (MI) leads to heart failure and fatal ventricular rupture, while optimal healing requires timely induction and resolution of inflammation. This study tested the hypothesis that heat shock…