Xinya Li
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View article: New biomarkers to predict the need for surgery of necrotizing enterocolitis: a study based on abdominal X-ray radiomics and machine learning
New biomarkers to predict the need for surgery of necrotizing enterocolitis: a study based on abdominal X-ray radiomics and machine learning Open
We identified new parameters of abdominal X-rays in patients with NEC to assess the feasibility of surgical treatment and may provide supporting clinical guidance to clinicians.
View article: Lung function as a modifiable risk factor for Ischemic Stroke: Evidence from the UK biobank
Lung function as a modifiable risk factor for Ischemic Stroke: Evidence from the UK biobank Open
This study underscores the importance of monitoring lung function, particularly at the community level, as a preventive measure against ischemic stroke. Given the aging global population, early detection and management of declining lung fu…
View article: Association between long-term (current) aspirin use and sepsis-related delirium in elderly patients: a retrospective cohort study
Association between long-term (current) aspirin use and sepsis-related delirium in elderly patients: a retrospective cohort study Open
In elderly patients, long-term (current) aspirin use is negatively associated with the incidence of SAD and is also linked to improved clinical outcomes.
View article: Where are we going for the treatment in ischaemic stroke: a comprehensive study of investigator-sponsored randomised controlled trials, 1990–2024
Where are we going for the treatment in ischaemic stroke: a comprehensive study of investigator-sponsored randomised controlled trials, 1990–2024 Open
Background Until recently, a comprehensive understanding of the current development status and emerging trends of investigator-sponsored randomised controlled trials (RCTs) for the treatment of ischaemic stroke (IS) on a global scale remai…
View article: Sensory Afferent Neural Circuits Mediate Electroacupuncture to Improve Swallowing Function in a Post‐Stroke Dysphagia Mouse Model
Sensory Afferent Neural Circuits Mediate Electroacupuncture to Improve Swallowing Function in a Post‐Stroke Dysphagia Mouse Model Open
Background Electroacupuncture (EA) has been reported to improve post‐stroke dysphagia (PSD) effectively. However, the underlying afferent neural circuit and neurological mechanism involved in improving PSD remain poorly understood. Methods…
View article: <scp>ADAM17</scp>/<scp>PTGS2</scp> Facilitates Pulmonary Fibrosis by Regulating Ferroptosis
<span>ADAM17</span>/<span>PTGS2</span> Facilitates Pulmonary Fibrosis by Regulating Ferroptosis Open
Pulmonary fibrosis (PF) is a chronic and progressive interstitial lung disease characterised by excessive deposition of extracellular matrix (ECM), resulting in high mortality rates. In this study, we provide evidence that ADAM17/PTGS2 pla…
View article: The triglyceride glucose index and delirium risk in sepsis patients: A causal inference study
The triglyceride glucose index and delirium risk in sepsis patients: A causal inference study Open
Background Sepsis, a grave systemic infection, presents substantial health challenges. While insulin resistance frequently occurs in sepsis conditions, its relationship with sepsis‐associated delirium remains insufficiently explored. Aim T…
View article: Inverse association between atherogenic index of plasma and testosterone in US adult males: A large cross-sectional study from the NAHNES 2011–2016
Inverse association between atherogenic index of plasma and testosterone in US adult males: A large cross-sectional study from the NAHNES 2011–2016 Open
Background and objectives The atherogenic index of plasma (AIP), defined as log10 (triglycerides/high-density lipoprotein cholesterol), serves as a biomarker for atherosclerosis and cardiovascular disease (CVD). It is also associated with …
View article: Identification of key chromium resistance genes in Cellulomonas using transcriptomics
Identification of key chromium resistance genes in Cellulomonas using transcriptomics Open
Cellulomonas fimi Clb-11 can reduce high toxic Cr(VI) to less toxic Cr(III), and transcriptomics was used to reveal the key Cr(VI) uptake and reduction genes of C. fimi Clb-11 in this study. The results showed that under 0.5 mM Cr(VI) stre…
View article: Integrating CT-based radiomics and clinical features to better predict the prognosis of acute pancreatitis
Integrating CT-based radiomics and clinical features to better predict the prognosis of acute pancreatitis Open
Objectives To develop and validate the performance of CT-based radiomics models for predicting the prognosis of acute pancreatitis. Methods All 344 patients (51 ± 15 years, 171 men) in a first episode of acute pancreatitis (AP) were retros…
View article: Association of geriatric nutritional risk index with total testosterone in elderly adults in the US: evidence from NHANES 2011-2016
Association of geriatric nutritional risk index with total testosterone in elderly adults in the US: evidence from NHANES 2011-2016 Open
Background and objectives There is growing evidence that deficiencies in specific nutrients can impact testosterone levels in older men. However, research examining the predictive value of overall nutritional status on testosterone levels …
View article: Association between plasma trans fatty acid levels and rheumatoid arthritis: a cross-sectional study using NHANES 1999–2000 and 2009–2010 data in US adults
Association between plasma trans fatty acid levels and rheumatoid arthritis: a cross-sectional study using NHANES 1999–2000 and 2009–2010 data in US adults Open
Objective While earlier research has indicated that trans fatty acids (TFAs) are detrimental to cardiovascular health as well as other conditions, the purpose of this study is to look into any possible connections between trans fatty acids…
View article: A Cutting Edge Review of Cross-Cultural Marketing and Consumer Behaviour Analysis - A Data-Driven Strategy
A Cutting Edge Review of Cross-Cultural Marketing and Consumer Behaviour Analysis - A Data-Driven Strategy Open
Cross-cultural marketing faces unprecedented challenges and opportunities in the context of globalisation and digitalisation. This paper provides an overview of key topics in cross-cultural marketing, discusses the importance of consumer b…
View article: The Latest Progress in the Application of Telitacicept in Autoimmune Diseases
The Latest Progress in the Application of Telitacicept in Autoimmune Diseases Open
So far, the efficacy and safety of telitacicept in autoimmune diseases have been fully demonstrated in clinical practice. There are still many unresolved issues regarding the timing of initiation and discontinuation, still needs to be eval…
View article: Immune checkpoint inhibitors-related thyroid dysfunction: influencing factor analysis, prediction model development, and management strategy proposal
Immune checkpoint inhibitors-related thyroid dysfunction: influencing factor analysis, prediction model development, and management strategy proposal Open
This study offers comprehensive insights into managing ICI-TD, potentially enhancing tailored cancer immunotherapy management.
View article: Mediating effect of adiponectin between free fatty acid and tumor necrosis factor-α in patients with diabetes
Mediating effect of adiponectin between free fatty acid and tumor necrosis factor-α in patients with diabetes Open
Background/Objectives Increased free fatty acid (FFA) promotes adiponectin secretion in healthy subjects and induces inflammation in diabetes. Given the potential pro-inflammatory role of adiponectin in “adiponectin paradox”, we performed …
View article: Association between modified frailty index and postoperative delirium in patients after cardiac surgery: A cohort study of 2080 older adults
Association between modified frailty index and postoperative delirium in patients after cardiac surgery: A cohort study of 2080 older adults Open
Aim To evaluate the association between frailty and postoperative delirium (POD) in elderly cardiac surgery patients. Methods A retrospective study was conducted of older patients admitted to the intensive care unit after cardiac surgery a…
View article: RBL: A Multimodal Emotion Analysis Model Based on Language Guided Transformer
RBL: A Multimodal Emotion Analysis Model Based on Language Guided Transformer Open
Emotional analysis has important value in the economic and social fields such as public opinion analysis, market research and risk prediction. Nowadays, the rapid development of short video media has led to the expansion of emotional analy…
View article: The hospital frailty risk score effectively predicts adverse outcomes in patients with atrial fibrillation in the intensive care unit
The hospital frailty risk score effectively predicts adverse outcomes in patients with atrial fibrillation in the intensive care unit Open
Background Atrial fibrillation (AF) and frailty are significant global public health problems associated with advancing age. However, the relationship between frailty and older patients with AF in the intensive care unit (ICU) has not been…
View article: Association between nephrotic syndrome and tuberculosis in ICU patients: A cross-sectional study of the MIMIC-IV database
Association between nephrotic syndrome and tuberculosis in ICU patients: A cross-sectional study of the MIMIC-IV database Open
Background This study investigated hospital mortality rates among patients with nephrotic syndrome (NS) and tuberculosis (TB) using data from the Medical Information Mart for Intensive Care IV version 2.2 (MIMIC-IV v2.2) database. The aim …
View article: Therapeutic drug monitoring guidelines in oncology: what do we know and how to move forward? Insights from a systematic review
Therapeutic drug monitoring guidelines in oncology: what do we know and how to move forward? Insights from a systematic review Open
Background: Compared with anti-infective drugs, immunosuppressants and other fields, the application of therapeutic drug monitoring (TDM) in oncology is somewhat limited. Objective: We aimed to provide a comprehensive understanding of TDM …
View article: Scope, design, and reporting of prediction models for antineoplastic drugs‐related adverse drug events: A systematic review of machine learning and traditional modeling
Scope, design, and reporting of prediction models for antineoplastic drugs‐related adverse drug events: A systematic review of machine learning and traditional modeling Open
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View article: Phenotypes of patients with systemic sclerosis in the Chinese Han population: A cluster analysis
Phenotypes of patients with systemic sclerosis in the Chinese Han population: A cluster analysis Open
Objective Systemic sclerosis (SSc) is a heterogeneous connective tissue disease that is commonly subdivided into limited cutaneous SSc (lcSSc) and diffuse cutaneous SSc (dcSSc) based on the extent of skin involvement. This subclassificatio…
View article: Predictors of rapidly progressive interstitial lung disease and prognosis in Chinese patients with anti-melanoma differentiation-associated gene 5-positive dermatomyositis
Predictors of rapidly progressive interstitial lung disease and prognosis in Chinese patients with anti-melanoma differentiation-associated gene 5-positive dermatomyositis Open
Background Rapidly progressive interstitial lung disease (RP-ILD) is the most serious complication of anti-melanoma differentiation-associated gene 5-positive dermatomyositis (anti-MDA5 + DM). This study was performed to assess the prognos…
View article: Development of ZD2767P–carboxypeptidase G2–ultrasound therapy against cisplatin-resistant cancer
Development of ZD2767P–carboxypeptidase G2–ultrasound therapy against cisplatin-resistant cancer Open
OPINION article Front. Oncol., 18 May 2023Sec. Pharmacology of Anti-Cancer Drugs Volume 13 - 2023 | https://doi.org/10.3389/fonc.2023.1151613