Explanipedia

A Rare Ocular Manifestation of Lipoid Proteinosis Open

Xinyi Ng, Jessica Mpt, Emily Ang · 2025

Lipoid proteinosis (LP) is a rare genetic disorder passed down in an autosomal recessive pattern. It affects multiple body systems and is marked by the abnormal buildup of hyaline material in different tissues. These deposits lead to chang…

Graphical Abstract: Angew. Chem. Int. Ed. 12/2024 Open

Anna Hartmann, Tobias E. Schrader, Stefan Kubik, Markus Braun, S Madrahimov , et al. · 2024

Lithium-Ion BatteriesIn their Communication (e202315628), De-en Jiang et al. reveal through machine-learning force field molecular dynamics simulations the superionic Li + transport in glassy LiTaCl 6 via adynamic "monkey bar" mechanism.

Graphisches Inhaltsverzeichnis: Angew. Chem. 12/2024 Open

Cristina Mayor‐Ruiz, Xiaoyu Tang, Günter Wulff, Thomas Schräder, Stefan Kubik , et al. · 2024

The most important quality of arole model is their ability to inspire and positively influence others through their actions, integrity,a nd empathy… My motto is:' The journey of athousand miles begins with as ingle step.' " Find out more a…

Preferences for potential benefits and risks for gene therapy in the treatment of sickle cell disease Open

Juan Marcos González, Jui‐Chen Yang, Shelby D. Reed, Ting-Hsuan Lee, Xinyi Ng , et al. · 2023

Objective of this study is to quantify benefit-risk tradeoffs pertaining to potential gene therapies among adults and parents/caregivers of children with sickle cell disease (SCD). A discrete-choice experiment survey was developed in which…

Adaptation of the WOMAC for Use in a Patient Preference Study Open

Sarah Stothers Rosenberg, Xinyi Ng, Carol Mansfield, Christine Poulos, Holly L. Peay , et al. · 2023

Table of Contents Open

Tommi Tervonen, Jorien Veldwijk, Katherine Payne, Xinyi Ng, Bennett Levitan , et al. · 2023

Quantitative Benefit-Risk Assessment in Medical Product Decision Making: A Good Practices Report of an ISPOR Task Force Open

Tommi Tervonen, Jorien Veldwijk, Katherine Payne, Xinyi Ng, Bennett Levitan , et al. · 2023

Illustrating Emerging Good Practices for Quantitative Benefit-Risk Assessment: A Hypothetical Case Study of Systemic Biologic Treatments for Plaque Psoriasis Open

Leila G. Lackey, Xinyi Ng, Jorien Veldwijk, Praveen Thokala, Bennett Levitan , et al. · 2023

A Versatile and Scalable Platform That Streamlines Data Collection for Patient-Centered Studies: Usability and Feasibility Study Open

Haley Huang, Sofia Aschettino, Nasim Lari, Ting-Hsuan Lee, Sarah Stothers Rosenberg , et al. · 2022

Background The Food and Drug Administration Center for Biologics Evaluation and Research (CBER) established the Biologics Effectiveness and Safety (BEST) Initiative with several objectives, including the expansion and enhancement of CBER’s…

Versatile and Scalable Platform Streamlines Data Collection for Patient-Centered Studies (Preprint) Open

Hussein Ezzeldin, Haley Huang, Sofia Aschettino, Nasim Lari, Ting-Hsuan Lee , et al. · 2022

BACKGROUND The Food and Drug Administration (FDA) Center for Biologics Evaluation and Research (CBER) established the Biologics Effectiveness and Safety (BEST) Initiative with several objectives, including to expand and enhance CBER’s acc…

Psychometric Validation of the EQ-5D-3L in Patients with Nontuberculous Mycobacterial (NTM) Lung Disease Caused by Mycobacterium avium Complex (MAC) Open

Anuj Shah, Xinyi Ng, Ruchit Shah, Caitlyn T. Solem, Ping Wang , et al. · 2021

EQ-5D-3L exhibited evidence of validity and reliability but poor responsiveness to clinically meaningful changes in patients with MAC-LD.

1400. Physician Attitudes towards Combination Vaccine Use in Infants up to 24 months of age in the United States (US) Open

Ya-Ting Chen, Xinyi Ng, Tanaz Petigara, Jyoti Aggarwal, Jenna Bhaloo , et al. · 2020

Background Combination vaccines reduce the number of injections and improve the timeliness of vaccination coverage. US Advisory Committee on Immunization Practices (ACIP) recommendations state that combination vaccines are generally prefer…

1399. Parental Perceptions of the Childhood Vaccination Schedule and Combination Vaccines in the United States (US) Open

Tanaz Petigara, Xinyi Ng, Ya-Ting Chen, Jyoti Aggarwal, Jenna Bhaloo , et al. · 2020

Background Ten different vaccine series are recommended by the US Advisory Committee on Immunization Practices from birth to 18 months. Combination vaccines can reduce the number of injections and visits required to complete the schedule i…

Patient and caregiver benefit‐risk preferences for nonmetastatic castration‐resistant prostate cancer treatment Open

Sandy Srinivas, Ateesha F. Mohamed, Sreevalsa Appukkuttan, Marc Botteman, Xinyi Ng , et al. · 2020

Background Recently approved second‐generation androgen receptor inhibitors (SGARIs) for non‐metastatic castration‐resistant prostate cancer (nmCRPC) have similar efficacy but differ in safety profiles. We used a discrete choice experiment…

Physician preferences for non-metastatic castration-resistant prostate cancer treatment Open

Sandy Srinivas, Ateesha F. Mohamed, Sreevalsa Appukkuttan, Marc Botteman, Xinyi Ng , et al. · 2020

PRO69 PATIENT AND CAREGIVER PREFERENCES FOR CHARACTERISTICS OF TREATMENT IN HEMOPHILIA A: LITERATURE REVIEW AND QUALITATIVE RESEARCH Open

N. Li, Marc Botteman, Namita Joshi, Xinyi Ng, Erica Horodniceanu , et al. · 2019

Graphical Abstract: Angew. Chem. Int. Ed. 9/2019 Open

Jie‐Sheng Chen, Thomas W. Ebbesen, S Kitagawa, Stephen L. Buchwald, John H. Hartwig , et al. · 2019

from GDCh, Postfach 900440, D-60444 Frankfurt am Main, Germany.

Patient-reported outcomes in individuals with hepatitis C virus infection treated with elbasvir/grazoprevir Open

Xinyi Ng, Chizoba Nwankwo, Jean Marie Arduino, Shelby Corman, Kathryn Lasch , et al. · 2018

NCT02358044.

Caregivers' Priorities and Observed Outcomes of Attention-Deficit Hyperactivity Disorder Medication for Their Children Open

Melissa Ross, Vy Nguyen, John F. P. Bridges, Xinyi Ng, Gloria Reeves , et al. · 2017

Objective: To document variability among caregivers' priorities when considering medication to treat their Children's attention-deficit hyperactivity disorder (ADHD) and explore associations between these priorities and medication-related …

Understanding systemic lupus erythematosus patients' desired outcomes and their perceptions of the risks and benefits of using corticosteroids Open

Xinyi Ng, Susan dosReis, Robert S. Beardsley, Laurence S. Magder, C. Daniel Mullins , et al. · 2017

Introduction The use of corticosteroids in systemic lupus erythematosus (SLE) patients requires difficult trade-offs between efficacy and risk of toxicity. This qualitative study examined SLE patients' most desired outcomes and their conce…

Caregiver Treatment Preferences for Children with a New Versus Existing Attention-Deficit/Hyperactivity Disorder Diagnosis Open

Susan dosReis, Alex Park, Xinyi Ng, Emily Frosch, Gloria Reeves , et al. · 2016

Preferences for ADHD treatment differ based on the duration of the child's ADHD. Acknowledging that preferences change over the course of care could facilitate patient/family-centered care planning across a range of resources and a multidi…

ELICITING PATIENT PREFERENCES FOR TREATMENT OUTCOMES IN SYSTEMIC LUPUS ERYTHMATOSUS Open

Xinyi Ng, C. Daniel Mullins, Susan dosReis · 2016

Pulmonologist Involvement, Stage-Specific Treatment, and Survival in Adults with Non–Small Cell Lung Cancer and Chronic Obstructive Pulmonary Disease Open

Janaki Deepak, Xinyi Ng, Josephine Feliciano, Li Mao, Amy J. Davidoff · 2015

Pulmonologist management had a positive association with rates of stage-specific treatment in both groups and overall survival in early-stage NSCLC. These results provide preliminary support for the recently published guidelines emphasizin…

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