Xue‐Ning Yang
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Author Swipe
View article: Genomic pathogenic alterations in the SWI/SNF complex compromise the outcomes of immunotherapy in Chinese patients with KRAS-mutant NSCLC by downregulating STING expression
Genomic pathogenic alterations in the SWI/SNF complex compromise the outcomes of immunotherapy in Chinese patients with KRAS-mutant NSCLC by downregulating STING expression Open
View article: Effect of Glucagon-like Peptide-1 Receptor Agonists on Gastric Residual Volume and Quality of Bowel Preparation in Patients Undergoing Painless Gastroenteroscopy: A Meta-Analysis
Effect of Glucagon-like Peptide-1 Receptor Agonists on Gastric Residual Volume and Quality of Bowel Preparation in Patients Undergoing Painless Gastroenteroscopy: A Meta-Analysis Open
View article: Supplementary Table S6 from Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer
Supplementary Table S6 from Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer Open
Table S6. The circulating tumor DNA mutation results for 4 patients with lead time over 30 months.
View article: Supplementary Figure S4 from Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer
Supplementary Figure S4 from Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer Open
Supplementary Figure S4. Kaplan-Meier analysis of the survival time since last blood, comparing patients with longitudinal undetectable MRD to those with longitudinal detectable MRD (last blood draw positive), excluding synchronous recurre…
View article: Supplementary Figure S2 from Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer
Supplementary Figure S2 from Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer Open
Supplementary Figure S2. Kaplan-Meier Analysis of Disease-Free Survival (DFS) in the Overall Population.
View article: Data from Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer
Data from Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer Open
Purpose:The prognostic value of molecular residual disease (MRD) in non–small cell lung cancer (NSCLC) is well established, with treatment-guiding results anticipated. Here, we present updated analyses from our previously published cohort …
View article: Supplementary Figure S5 from Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer
Supplementary Figure S5 from Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer Open
Supplementary Figure S5. CT and MRI images of patients with brain-only metastases who had longitudinal undetectable MRD. The red arrows indicate the location of metastatic lesions.
View article: Supplementary Figure S6 from Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer
Supplementary Figure S6 from Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer Open
Supplementary Figure S6. Kaplan-Meier Analysis of Disease-Free Survival (DFS) for patients with intermittently detectable MRD versus persistently detectable MRD. Patients who spontaneously converted to undetectable MRD after the first posi…
View article: Supplementary Figure S8 from Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer
Supplementary Figure S8 from Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer Open
Supplementary Figure S8. (A) Estimated hazard rate curves for event occurrences in stage II/III patients with landmark undetectable MRD, who received adjuvant therapy. (B) Estimated hazard rate curves for event occurrences in stage II/III …
View article: Supplementary Table S3 from Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer
Supplementary Table S3 from Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer Open
Table S3. Univariate and Multivariate Cox Regression Analysis.
View article: Supplementary Table S2 from Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer
Supplementary Table S2 from Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer Open
Table S2. Cox regression for progression-free survival based on longitudinal MRD detection.
View article: Supplementary Table S5 from Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer
Supplementary Table S5 from Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer Open
Table S5. The circulating tumor DNA mutation results for 5 MRD+ patients without recurrence.
View article: Supplementary Figure S1 from Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer
Supplementary Figure S1 from Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer Open
Supplementary Figure S1. ctDNA-MRD detection framework
View article: Supplementary Table S1 from Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer
Supplementary Table S1 from Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer Open
Table S1. Performance Metrics of Landmark and Longitudinal MRD Analyses Stratified by Tumor Type.
View article: Supplementary Figure S3 from Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer
Supplementary Figure S3 from Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer Open
Supplementary Figure S3. (A) Kaplan–Meier analysis of disease-free survival (DFS) stratified by landmark MRD status for LUAD patients. (B) Kaplan–Meier analysis of DFS stratified by longitudinal MRD status for LUAD patients. (C) Kaplan-Mei…
View article: Supplementary Table S4 from Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer
Supplementary Table S4 from Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer Open
Table S4. Clinical characteristics of 13 cases recurred with longitudinal undetected MRD.
View article: Supplementary Figure S7 from Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer
Supplementary Figure S7 from Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer Open
Supplementary Figure S7. Univariate cox analysis of MRD lead time with ctDNA level and maxVAF, as continuous variables
View article: Supplementary Table S7 from Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer
Supplementary Table S7 from Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer Open
Table S7. Comparison of baseline characteristics for patients exploring the predictive value of undetectable and detectable MRD with or without adjuvant therapy.
View article: The Efficacy of the New Energy Vehicle Mandate Policy on Passenger Vehicle Market in China
The Efficacy of the New Energy Vehicle Mandate Policy on Passenger Vehicle Market in China Open
This paper aims to assess the impact of the New Energy Vehicle (NEV) mandate policy on the passenger vehicle market in China, with a focus on its effectiveness in promoting NEV adoption. In response to global climate goals and energy secur…
View article: Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer
Follow-up Analysis Enhances Understanding of Molecular Residual Disease in Localized Non–Small Cell Lung Cancer Open
Purpose: The prognostic value of molecular residual disease (MRD) in non–small cell lung cancer (NSCLC) is well established, with treatment-guiding results anticipated. Here, we present updated analyses from our previously published cohort…
View article: Relationship of vegetarianism with body weight loss and ASCVD
Relationship of vegetarianism with body weight loss and ASCVD Open
Introduction The association between a plant-based diet and weight loss and atherosclerotic cardiovascular disease (ASCVD) has not been fully elucidated. We performed a pooled analysis and Mendelian randomization (MR) analysis to investiga…
View article: Lipid-associated macrophages for osimertinib resistance and leptomeningeal metastases in NSCLC
Lipid-associated macrophages for osimertinib resistance and leptomeningeal metastases in NSCLC Open
Leptomeningeal metastases (LMs) remain a devastating complication of non-small cell lung cancer (NSCLC), particularly following osimertinib resistance. We conducted single-cell RNA sequencing on cerebrospinal fluid (CSF) from EGFR-mutant N…
View article: Neoadjuvant SHR-1701 with or without chemotherapy in unresectable stage III non-small-cell lung cancer: A proof-of-concept, phase 2 trial
Neoadjuvant SHR-1701 with or without chemotherapy in unresectable stage III non-small-cell lung cancer: A proof-of-concept, phase 2 trial Open
We conducted a proof-of-concept, phase 2 trial to assess neoadjuvant SHR-1701 with or without chemotherapy, followed by surgery or radiotherapy, and then consolidation SHR-1701 in unresectable stage III non-small-cell lung cancer (NSCLC). …
View article: Groundwater exhibits spatially opposing trends during the Australian Millennium Drought
Groundwater exhibits spatially opposing trends during the Australian Millennium Drought Open
The adverse impacts of Australia’s Millennium Drought on both surface and groundwater hydrological systems are extensively documented. During the Millennium Drought, the Murray Basin experienced a severe rainfall deficit. Our study revisit…
View article: 111P Enhancing negative predictive value of landmark undetectable molecular residual disease with baseline cell free DNA features based XGBoost model in resected non-small cell lung cancer
111P Enhancing negative predictive value of landmark undetectable molecular residual disease with baseline cell free DNA features based XGBoost model in resected non-small cell lung cancer Open
Circulating tumor DNA (ctDNA)-molecular residual disease (MRD) has been recognized as a robust prognostic biomarker post-lung cancer surgery. However, its application in adjuvant therapy guidance is limited by the insufficient sensitivity …
View article: Strong Agricultural Resilience to 2022 Southern China Drought
Strong Agricultural Resilience to 2022 Southern China Drought Open
Meteorological drought, especially when influenced by human activities, significantly impacts agriculture. We assessed the Yangtze River Basin (YRB)’s crop ecosystem resilience during the 2022 southern China drought. Using the elasticity f…
View article: Understanding the Propagation of Meteorological Drought to Groundwater Drought: A Case Study of the North China Plain
Understanding the Propagation of Meteorological Drought to Groundwater Drought: A Case Study of the North China Plain Open
As extreme climate events become more common with global warming, groundwater is increasingly vital for combating long-term drought and ensuring socio-economic and ecological stability. Currently, the mechanism of meteorological drought pr…
View article: Both Meteorological Droughts and Human Activities Modulated Groundwater Variations in Northern Loess Plateau
Both Meteorological Droughts and Human Activities Modulated Groundwater Variations in Northern Loess Plateau Open
View article: Rainfall and Maximum Temperature are Dominant Climatic Factors Influencing Apsim-Maize Cultivar Parameters Sensitivity in Semiarid Regions
Rainfall and Maximum Temperature are Dominant Climatic Factors Influencing Apsim-Maize Cultivar Parameters Sensitivity in Semiarid Regions Open
View article: Plasma EBV quantification is associated with the efficacy of immune checkpoint blockade and disease monitoring in patients with primary pulmonary lymphoepithelioma‐like carcinoma
Plasma EBV quantification is associated with the efficacy of immune checkpoint blockade and disease monitoring in patients with primary pulmonary lymphoepithelioma‐like carcinoma Open
Objectives Primary pulmonary lymphoepithelioma‐like carcinoma (PLELC) is a subtype of lung carcinoma associated with the Epstein–Barr virus (EBV). The clinical predictive biomarkers of immune checkpoint blockade (ICB) in PLELC require furt…