Abstract Metal‐organic framework (MOF) has been widely used as filler of mixed‐matrix membranes (MMMs) because of their tunable pore sizes, large surface areas, and rich functional groups. However, a relatively high diffusion barrier in the framework of bulk MOF fillers inevitably reduces gas permeability. Introduction of hierarchically porous structure represents an effective method for reducing guest diffusion resistance with no compromise in gas selectivity. In this study, hierarchical ZIF‐8 (H‐ZIF‐8) was prepa…

Abstract Bacterial plant diseases, worsened by biofilm‐mediated resistance, are increasingly threatening global food security. Numerous attempts have been made to develop agrochemicals that inhibit biofilms, however, their ineffective foliar deposition and difficulty in removing mature biofilms remain major challenges. Herein, multifunctional three‐component supramolecular nano‐biscuits (NI6R@CB[7]@ β ‐CD) are successfully engineered via ordered self‐assembly between two macrocycles [cucurbit[7]uril (CB[7]), β ‐cy…

Neural stem cells (NSCs) possess pluripotent characteristics, proliferative capacity, and the ability to self-renew. In the context of neurological diseases, transplantation of NSCs has been shown to facilitate neurological repair through paracrine mechanisms. NSC-derived small extracellular vesicles (NSC-sEVs), a prominent component of the NSC secretome, play a crucial role in modulating various physiological and pathological processes, such as regulating the NSC microenvironment, promoting endogenous NSC differe…

Nasopharyngeal carcinoma (NPC) is a highly invasive form of head and neck cancer that arises from nasopharyngeal epithelial cells. Celastrol and curcumin, both derived from traditional Chinese medicine, have demonstrated antitumor potential. However, the clinical application of these compounds is limited by their low bioavailability and/or toxicity. Cancer cell viability, apoptosis, autophagy, ferroptosis, and mitochondrial fission- and fusion-related proteins were evaluated following treatment with celastrol alon…

The site‐specific labeling of peptides and proteins is a powerful tool for investigating biological processes. It is demonstrated that the powerful thiol‐specific labeling reagent vinyltetrazine activates prodrugs and enables 18 F and near‐infrared dual‐modality imaging. It is predicted that substitutions at the 3‐position of tetrazine can affect the labeling efficiency, bioorthogonal kinetics, and stability. Six vinyltetrazines with different 3‐position modifications exhibit rapid labeling and, subsequently, bioo…