Xi Mo
YOU?
Author Swipe
View article: A-297 Trends in Respiratory Pathogen Infection Spectrum Post-Pandemic among Chinese Children
A-297 Trends in Respiratory Pathogen Infection Spectrum Post-Pandemic among Chinese Children Open
Background Respiratory tract infections (RTIs) are a significant global health concern ranging from common colds to severe respiratory illnesses, particularly in children among underdeveloped regions. Despite the development and deployment…
View article: Allergen-specific sublingual immunotherapy altered gut microbiota in patients with allergic rhinitis
Allergen-specific sublingual immunotherapy altered gut microbiota in patients with allergic rhinitis Open
Introduction Allergen-specific immunotherapy (AIT) induces long-term immune tolerance to allergens and is effective for treating allergic rhinitis (AR). However, the impact of sublingual immunotherapy (SLIT) on gut microbiota from AR patie…
View article: Diagnostic performance of a multiplexed gastrointestinal PCR panel for identifying diarrheal pathogens in children undergoing hematopoietic stem cell transplant
Diagnostic performance of a multiplexed gastrointestinal PCR panel for identifying diarrheal pathogens in children undergoing hematopoietic stem cell transplant Open
Background Diarrhea is a common complication of hematopoietic stem cell transplantation (HSCT) and is associated with substantial morbidity, but its etiology is often unknown. Etiologies of diarrhea in this population include infectious ca…
View article: 664. Diagnostic Performance of a Multiplexed Gastrointestinal PCR Panel on Identifying Diarrheal Pathogens in Children Undergoing Hematopoietic Stem Cell Transplant
664. Diagnostic Performance of a Multiplexed Gastrointestinal PCR Panel on Identifying Diarrheal Pathogens in Children Undergoing Hematopoietic Stem Cell Transplant Open
Background Diarrhea is a common complication of hematopoietic stem cell transplantation (HSCT) and associated with substantial morbidity, but the etiology is often not identified. The objectives of this study were to evaluate 1) whether th…
View article: Polymicrobial anaerobic bacterial meningitis secondary to dermal sinus: a case report
Polymicrobial anaerobic bacterial meningitis secondary to dermal sinus: a case report Open
Anaerobic bacterial meningitis is a rare infectious disease, and there are some special predisposing factors for it. We report a case of polymicrobial anaerobic bacterial meningitis in a nine-month-old boy who visited our hospital due to "…
View article: Analysis of gut microbiota alteration and application as an auxiliary prognostic marker for sepsis in children: a pilot study
Analysis of gut microbiota alteration and application as an auxiliary prognostic marker for sepsis in children: a pilot study Open
Overall, we confirmed that gut microbiota disturbance occurred in the children with sepsis, and changes in the fecal microbiota were closely related to clinical characteristics. Elucidation of such dysbiosis could improve our understanding…
View article: Staphylococcal Superantigen-Like Protein 10 (SSL10) induces necroptosis through TNFR1 activation of RIPK3-dependent signal pathways
Staphylococcal Superantigen-Like Protein 10 (SSL10) induces necroptosis through TNFR1 activation of RIPK3-dependent signal pathways Open
Staphylococcal aureus ( S. aureus ) infection can lead to a wide range of diseases such as sepsis and pneumonia. Staphylococcal superantigen like (SSL) proteins, specifically expressed by S. aureus , are shown to be involved in immune evas…
View article: Preliminary analyses of scRNA sequencing and immunohistochemistry of children's lung tissues indicate the expression of SARS‐CoV‐2 entry‐related genes may not be the key reason for the milder syndromes of COVID‐19 in children
Preliminary analyses of scRNA sequencing and immunohistochemistry of children's lung tissues indicate the expression of SARS‐CoV‐2 entry‐related genes may not be the key reason for the milder syndromes of COVID‐19 in children Open
Accumulating data have suggested that the SARS-CoV-2 infection in children is relatively rare and less critical when compared to adults.1 However, a recent study demonstrated that children and adults have comparable chances of infection by…
View article: Development and Multicenter Assessment of a Reference Panel for Clinical Shotgun Metagenomics for Pathogen Detection
Development and Multicenter Assessment of a Reference Panel for Clinical Shotgun Metagenomics for Pathogen Detection Open
Background Clinical shotgun metagenomics for pathogen detection has been used in diagnosing infectious diseases. However, its technical assessments have been limited to reference standards by individual labs, single experimental workflow a…
View article: Exosomal microRNAs in Human Breast Milk: Potential Effect on Neonatal Breast Milk Jaundice
Exosomal microRNAs in Human Breast Milk: Potential Effect on Neonatal Breast Milk Jaundice Open
Background: The pathogenesis of breast milk jaundice (BMJ) remains unrevealed. While UGT1A1 gene has been extensively investigated in neonatal BMJ cases, the reason for down-regulation of UGT1A1 gene in neonatal BMJ has not been completely…
View article: A Diagnostic Panel of DNA Methylation Biomarkers for Lung Adenocarcinoma
A Diagnostic Panel of DNA Methylation Biomarkers for Lung Adenocarcinoma Open
Lung adenocarcinoma (LUAD) is one of the most common cancers and lethal diseases in the world. Recognition of the undetermined lung nodules at an early stage is useful for a favorable prognosis. However, there is no good method to identify…
View article: Evaluation of the BioFire FilmArray meningitis/encephalitis panel for the detection of bacteria and yeast in Chinese children
Evaluation of the BioFire FilmArray meningitis/encephalitis panel for the detection of bacteria and yeast in Chinese children Open
This study demonstrated the capability of the FilmArray ME panel in the diagnosis of bacterial and fungal meningitis and therefore its potential use in facilitating enhanced patient care.
View article: Identification of etiologic agents and clinical characteristics for patients suspected of having pertussis in a large Children’s Hospital in China
Identification of etiologic agents and clinical characteristics for patients suspected of having pertussis in a large Children’s Hospital in China Open
Our study highlights the importance of the timely and accurate diagnosis of pertussis based on both clinical symptoms and laboratory methods.
View article: Exploration of susceptible genes associatedwith Henoch–Schönlein purpura by whole exome sequencing
Exploration of susceptible genes associatedwith Henoch–Schönlein purpura by whole exome sequencing Open
Our findings are helpful for providing new methods and ideas for understanding the pathogenesis of HSP by detecting and analyzing gene mutations at the whole-exome level including multi-generation sequencing. MIF and MGAT5 may be new susce…
View article: A prediction panel with DNA methylation biomarkers for lung adenocarcinoma
A prediction panel with DNA methylation biomarkers for lung adenocarcinoma Open
Background: Lung adenocarcinoma accounts for more than 40% of lung cancer incidence. Thus, it is urgent to identify early-stage related markers. In this study, the effectiveness of CpG methylation on predicting lung adenocarcinoma was inve…
View article: Deficiency of SUMO-specific protease 1 induces arsenic trioxide-mediated apoptosis by regulating XBP1 activity in human acute promyelocytic leukemia
Deficiency of SUMO-specific protease 1 induces arsenic trioxide-mediated apoptosis by regulating XBP1 activity in human acute promyelocytic leukemia Open
Small ubiquitin-like modifier (SUMO)/sentrin-specific protease 1 (SENP1), a member of the SENP family, is highly expressed in several neoplastic tissues. However, the effect of SENP1 in acute promyelocytic leukemia (APL) has not been eluci…
View article: [Association of Cosmc gene mutation with susceptibility to Henoch-Schönlein purpura in children].
[Association of Cosmc gene mutation with susceptibility to Henoch-Schönlein purpura in children]. Open
The mutations c.393T>A and c.72A>G in the exon region of Cosmc gene in children with HSP are not associated with the onset of HSP.