Xiquan Hu
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View article: Functional connectivity in whole-brain and network analysis differentiates minimally conscious from unresponsive patients: a resting-state fNIRS study
Functional connectivity in whole-brain and network analysis differentiates minimally conscious from unresponsive patients: a resting-state fNIRS study Open
View article: TATTOO: Training-free AesTheTic-aware Outfit recOmmendation
TATTOO: Training-free AesTheTic-aware Outfit recOmmendation Open
The global fashion e-commerce market relies significantly on intelligent and aesthetic-aware outfit-completion tools to promote sales. While previous studies have approached the problem of fashion outfit-completion and compatible-item retr…
View article: Physical exercise promotes white matter repair after ischemic stroke
Physical exercise promotes white matter repair after ischemic stroke Open
White matter injury is a key factor impacting stroke recovery. Physical exercise can promote white matter repair. Immune cells, especially regulatory T (Treg) cells, contribute to strengthening white matter integrity, yet little is known a…
View article: Voluntary exercise alleviates neural functional deficits in Parkinson’s disease mice by inhibiting microglial ferroptosis via SLC7A11/ALOX12 axis
Voluntary exercise alleviates neural functional deficits in Parkinson’s disease mice by inhibiting microglial ferroptosis via SLC7A11/ALOX12 axis Open
Microglia are more susceptible to ferroptosis compared to neurons and astrocytes, which may compromise their phagocytic and clearance capabilities of α-synuclein (α-syn) in Parkinson's disease (PD). While the beneficial effects of physical…
View article: Enhancement of glymphatic function and cognition in chronic insomnia using low-frequency rTMS
Enhancement of glymphatic function and cognition in chronic insomnia using low-frequency rTMS Open
Study Objectives Low-frequency repetitive transcranial magnetic stimulation (LF-rTMS) is a promising treatment for chronic insomnia; however, its effectiveness in improving cognitive and glymphatic clearance functions remains unclear. We a…
View article: Important role of the right hemisphere in post-stroke cognitive impairment: a functional near-infrared spectroscopy study
Important role of the right hemisphere in post-stroke cognitive impairment: a functional near-infrared spectroscopy study Open
Unlike the left hemisphere activation strategy commonly used previously, our results suggest that the important role of the right hemisphere may be overlooked in PSCI patients with or without aphasia. Future treatment options and studies c…
View article: Effects of different types of high-definition transcranial electrical stimulation on visual working memory and contralateral delayed activity
Effects of different types of high-definition transcranial electrical stimulation on visual working memory and contralateral delayed activity Open
View article: CircFndc3b Mediates Exercise‐Induced Neuroprotection by Mitigating Microglial/Macrophage Pyroptosis via the ENO1/KLF2 Axis in Stroke Mice
CircFndc3b Mediates Exercise‐Induced Neuroprotection by Mitigating Microglial/Macrophage Pyroptosis via the ENO1/KLF2 Axis in Stroke Mice Open
Circular RNA (circRNA) plays a pivotal role in regulating neurological damage post‐ischemic stroke. Previous researches demonstrated that exercise mitigates neurological dysfunction after ischemic stroke, yet the specific contributions of …
View article: Development and Validation of a Nomogram for Predicting Non-Adherence to Continuous Positive Airway Pressure Therapy in Patients with Obstructive Sleep Apnea
Development and Validation of a Nomogram for Predicting Non-Adherence to Continuous Positive Airway Pressure Therapy in Patients with Obstructive Sleep Apnea Open
This study provided an effective nomogram for predicting CPAP non-adherence in OSA patients.
View article: Physical exercise‐induced <scp>circAnks1b</scp> upregulation promotes protective endoplasmic reticulum stress and suppresses apoptosis via <scp>miR</scp>‐130b‐5p/Pak2 signaling in an ischemic stroke model
Physical exercise‐induced <span>circAnks1b</span> upregulation promotes protective endoplasmic reticulum stress and suppresses apoptosis via <span>miR</span>‐130b‐5p/Pak2 signaling in an ischemic stroke model Open
Aims Physical exercise (PE) can accelerate post‐stroke recovery. This study investigated contributions of circRNAs to PE‐induced improvements in post‐stroke neurological function. Methods Rats subjected to transient middle cerebral artery …
View article: High-Frequency rTMS Broadly Ameliorates Working Memory and Cognitive Symptoms in Stroke Patients: A Randomized Controlled Trial
High-Frequency rTMS Broadly Ameliorates Working Memory and Cognitive Symptoms in Stroke Patients: A Randomized Controlled Trial Open
Objective To explore the efficacy and tolerability of high-frequency repetitive transcranial magnetic stimulation (rTMS) in the treatment of post-stroke working memory (WM) impairment and its changes in brain function. Methods In the prese…
View article: Blood Brain Barrier‐Crossing Delivery of Felodipine Nanodrug Ameliorates Anxiety‐Like Behavior and Cognitive Impairment in Alzheimer's Disease
Blood Brain Barrier‐Crossing Delivery of Felodipine Nanodrug Ameliorates Anxiety‐Like Behavior and Cognitive Impairment in Alzheimer's Disease Open
Alzheimer's disease (AD) is the most common age‐related neurodegenerative disorder leading to cognitive decline. Excessive cytosolic calcium (Ca 2+ ) accumulation plays a critical role in the pathogenesis of AD since it activates the NOD‐l…
View article: Discourse Task Type–Specific Linguistic Characteristics in Anomic Aphasia and Healthy Controls: Evidence From Mandarin–Chinese AphasiaBank
Discourse Task Type–Specific Linguistic Characteristics in Anomic Aphasia and Healthy Controls: Evidence From Mandarin–Chinese AphasiaBank Open
Purpose: This study was designed to examine the hypothesis that discourse task types influence language performance in Mandarin Chinese–speaking people and to reveal the discourse task-specific linguistic properties of persons with anomic …
View article: Physical Exercise Promotes the Protective Endoplasmic Reticulum Stress Through CircAnks1b/ miR-130-5p/ Pak2 Axis after Ischemic Stroke
Physical Exercise Promotes the Protective Endoplasmic Reticulum Stress Through CircAnks1b/ miR-130-5p/ Pak2 Axis after Ischemic Stroke Open
View article: Interactions between tDCS treatment and COMT Val158Met in poststroke cognitive impairment
Interactions between tDCS treatment and COMT Val158Met in poststroke cognitive impairment Open
This study found that COMT Val158Met has an interaction on the efficacy of prefrontal tDCS in cognitive function, which provides reference for future tDCS research and clinical application.
View article: Correct Information Unit Analysis in Different Discourse Tasks Among Persons With Anomic Aphasia Based on Mandarin AphasiaBank
Correct Information Unit Analysis in Different Discourse Tasks Among Persons With Anomic Aphasia Based on Mandarin AphasiaBank Open
Purpose: This study aimed to explore how well persons with anomic aphasia communicate information during discourse regarding quantity, quality, and efficiency compared to neurotypical controls, to investigate the influence of discourse tas…
View article: High-frequency repetitive transcranial magnetic stimulation promotes neural stem cell proliferation after ischemic stroke
High-frequency repetitive transcranial magnetic stimulation promotes neural stem cell proliferation after ischemic stroke Open
JOURNAL/nrgr/04.03/01300535-202408000-00031/figure1/v/2025-05-18T184447Z/r/image-tiff Proliferation of neural stem cells is crucial for promoting neuronal regeneration and repairing cerebral infarction damage. Transcranial magnetic stimula…
View article: Functional Alterations of the Basal Ganglia Are Associated with Voluntary Activation of the Core Stabilizing Muscles in Patients with Chronic Low Back Pain: A Cross-Sectional Study
Functional Alterations of the Basal Ganglia Are Associated with Voluntary Activation of the Core Stabilizing Muscles in Patients with Chronic Low Back Pain: A Cross-Sectional Study Open
Purpose. Deficits in voluntary activation of the core stabilizing muscles are consistently observed in patients with chronic low back pain (CLBP); however, the underlying neural mechanism remains unclear. This cross-sectional study aimed a…
View article: Exercise improved P2Y12-regulated microglial dynamics during stroke via endocannabinoid signaling
Exercise improved P2Y12-regulated microglial dynamics during stroke via endocannabinoid signaling Open
Microglia are vigilant housekeepers in the adult brain, they continually extend and retract their processes to survey their microenvironment. In a dependent manner involving P2Y12 receptors, microglia undergo morphological and functional c…
View article: TREM2 mediates physical exercise-promoted neural functional recovery in rats with ischemic stroke via microglia-promoted white matter repair
TREM2 mediates physical exercise-promoted neural functional recovery in rats with ischemic stroke via microglia-promoted white matter repair Open
View article: Screening diagnosis of executive dysfunction after ischemic stroke and the effects of transcranial magnetic stimulation: A prospective functional near‐infrared spectroscopy study
Screening diagnosis of executive dysfunction after ischemic stroke and the effects of transcranial magnetic stimulation: A prospective functional near‐infrared spectroscopy study Open
Background Post‐ischemic stroke executive impairment (PISEI) is a serious obstacle for patients to returning to their society and is currently difficult to screen early and clinically ineffective. Aim The aim of the study was to clarify wh…
View article: Exercise Improved P2Y12-Regulated Microglial Dynamics During Stroke Via Endocannabinoid Signaling
Exercise Improved P2Y12-Regulated Microglial Dynamics During Stroke Via Endocannabinoid Signaling Open
View article: Expert consensus on liver transplantation perioperative evaluation and rehabilitation for acute-on-chronic liver failure
Expert consensus on liver transplantation perioperative evaluation and rehabilitation for acute-on-chronic liver failure Open
Acute-on-chronic liver failure (ACLF) can be cured by liver transplantation; however, perioperative complications still affect posttransplant outcomes. In recent years, early rehabilitation for critical illness, liver disease, and surgery …
View article: Correction to: NLRP3-dependent microglial training impaired the clearance of amyloid-beta and aggravated the cognitive decline in Alzheimer’s disease
Correction to: NLRP3-dependent microglial training impaired the clearance of amyloid-beta and aggravated the cognitive decline in Alzheimer’s disease Open
After publication of the article, we recently identified after re-reviewing this manuscript that the image from the "Pixel intensity of Aβ 1-40 in hippocampus" in figure 4. B showed overlap with the comparison histogram in figure 4.D due t…
View article: Ultrasound Stimulation of Prefrontal Cortex Improves Lipopolysaccharide-Induced Depressive-Like Behaviors in Mice
Ultrasound Stimulation of Prefrontal Cortex Improves Lipopolysaccharide-Induced Depressive-Like Behaviors in Mice Open
Increasing evidence indicates that inflammatory responses may influence brain neurochemical pathways, inducing depressive-like behaviors. Ultrasound stimulation (US) is a promising non-invasive treatment for neuropsychiatric diseases. We i…
View article: Repetitive Transcranial Magnetic Stimulation Improves Neurological Function and Promotes the Anti-inflammatory Polarization of Microglia in Ischemic Rats
Repetitive Transcranial Magnetic Stimulation Improves Neurological Function and Promotes the Anti-inflammatory Polarization of Microglia in Ischemic Rats Open
Ischemic stroke (IS) is a severe neurological disease that is difficult to recovery. Previous studies have shown that repetitive transcranial magnetic stimulation (rTMS) is a promising therapeutic approach, while the exact therapy mechanis…
View article: Characteristics of systemic inflammation and brain iron deposition in Parkinson's disease patients
Characteristics of systemic inflammation and brain iron deposition in Parkinson's disease patients Open
Objective This study aimed at determining the characteristics of systemic inflammation and brain iron deposition in Parkinson's disease (PD) patients. Methods Thirty two PD patients and 30 gender‐ as well as age‐matched controls were enrol…
View article: Correction to: Chronic colitis exacerbates NLRP3-dependent neuroinflammation and cognitive impairment in middle-aged brain
Correction to: Chronic colitis exacerbates NLRP3-dependent neuroinflammation and cognitive impairment in middle-aged brain Open
View article: Physical Exercise Improved P2Y12-Regulated Microglial Dynamics and Protected Against Ischemic&nbsp;Stroke&nbsp;in the&nbsp;Brain&nbsp;via Endocannabinoid Signaling
Physical Exercise Improved P2Y12-Regulated Microglial Dynamics and Protected Against Ischemic Stroke in the Brain via Endocannabinoid Signaling Open
View article: Chronic colitis exacerbates NLRP3-dependent neuroinflammation and cognitive impairment in middle-aged brain
Chronic colitis exacerbates NLRP3-dependent neuroinflammation and cognitive impairment in middle-aged brain Open
Background Neuroinflammation is a major driver of age-related brain degeneration and concomitant functional impairment. In patients with Alzheimer’s disease, the most common form of age-related dementia, factors that enhance neuroinflammat…