Xuan Peng
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View article: The function and mechanisms of action of lysyl oxidase-like 3 (LOXL3) in cancers
The function and mechanisms of action of lysyl oxidase-like 3 (LOXL3) in cancers Open
Lysyl oxidase-like 3 (LOXL3) is a key member of the lysyl oxidase (LOX) family and belongs to the copper-dependent amine oxidase family. Its traditional core function is to catalyze the cross-linking of collagen and elastin in the extracel…
View article: Case Report: Experience of a case of cardiac arrest caused by postoperative pulmonary embolism and hepatic rupture induced by cardiopulmonary resuscitation
Case Report: Experience of a case of cardiac arrest caused by postoperative pulmonary embolism and hepatic rupture induced by cardiopulmonary resuscitation Open
Postoperative pulmonary embolism (PE) poses a serious threat to a patient's life. However, cases involving concurrent liver rupture are exceedingly rare. This report describes a case of a patient who experienced cardiac arrest due to PE fo…
View article: Interfacial evolution and toughening mechanisms in diffusion-bonded Nb/Nb5Si3 laminated composites
Interfacial evolution and toughening mechanisms in diffusion-bonded Nb/Nb5Si3 laminated composites Open
View article: Machine learning models for rapid prediction of chemicals’ life-cycle environmental impacts: Current status, challenges, and future directions
Machine learning models for rapid prediction of chemicals’ life-cycle environmental impacts: Current status, challenges, and future directions Open
View article: Epicatechin attenuates the stemness of liver cancer stem cells and tumorigenesis through DNA methylation-mediated inactivation of GINS1/HRAS
Epicatechin attenuates the stemness of liver cancer stem cells and tumorigenesis through DNA methylation-mediated inactivation of GINS1/HRAS Open
View article: Metabolomics analysis and mRNA/miRNA profiling reveal potential cardiac regulatory mechanisms in Yili racehorses under different training regimens
Metabolomics analysis and mRNA/miRNA profiling reveal potential cardiac regulatory mechanisms in Yili racehorses under different training regimens Open
Yili horses, a versatile breed from Xinjiang, China, are renowned for their racing abilities. However, studies on the links between cardiac morphology, function, and metabolic profiles with performance are limited. This study combined echo…
View article: The impact of combined use of probiotics and metformin on metabolic parameters in patients with polycystic ovary syndrome
The impact of combined use of probiotics and metformin on metabolic parameters in patients with polycystic ovary syndrome Open
This study amed to investigate the combined use of probiotics and metformin on metabolic parameters in patients with polycystic ovary syndrome (PCOS). 138 patients with PCOS were retrospectively included from January to December 2023 and d…
View article: Mechanisms of HRAS regulation of liver hepatocellular carcinoma for prognosis prediction
Mechanisms of HRAS regulation of liver hepatocellular carcinoma for prognosis prediction Open
View article: CFP: Low-overhead Profiling-based Intra-operator Parallelism Generation by Preserving Communication-Free Structures
CFP: Low-overhead Profiling-based Intra-operator Parallelism Generation by Preserving Communication-Free Structures Open
This paper introduces CFP, a system that search intra-operator parallelism configurations by leveraging runtime profiles of actual parallel programs. The key idea is to profile a limited space by identifying a new structure named ParallelB…
View article: Regulating Autophagy in Nanomedicine: Advancing Cancer Therapy
Regulating Autophagy in Nanomedicine: Advancing Cancer Therapy Open
Autophagy, a cellular process responsible for degrading and recycling damaged organelles and proteins, plays a crucial role in maintaining cellular homeostasis and responding to stress. In cancer therapy, autophagy exhibits dual roles, act…
View article: Ganoderma Lucidum-Derived Porous Carbon Loaded Nano-Flower Balls Metal Oxides for Energy Storage Application in Supercapacitors
Ganoderma Lucidum-Derived Porous Carbon Loaded Nano-Flower Balls Metal Oxides for Energy Storage Application in Supercapacitors Open
View article: Phase Evolution and Area Fractions of Coarse-Grain and Fine-Grain A15 in APC Nb<sub>3</sub>Sn Superconductors
Phase Evolution and Area Fractions of Coarse-Grain and Fine-Grain A15 in APC Nb<sub>3</sub>Sn Superconductors Open
Previous studies have shown that APC Nb3Sn strands based on the internal oxidation of Nb-Ta-Zr or Nb-Ta-Hf alloys had higher non-Cu critical current density (Jcs) than the state-of-the-art strands at high fields (e.g.…
View article: Pneumatic Retinopexy for Rhegmatogenous Retinal Detachment Outcomes
Pneumatic Retinopexy for Rhegmatogenous Retinal Detachment Outcomes Open
Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.
View article: Open-loop narrowband magnetic particle imaging based on mixed-frequency harmonic magnetization response
Open-loop narrowband magnetic particle imaging based on mixed-frequency harmonic magnetization response Open
Introduction Magnetic particle imaging (MPI), a radiation-free, dynamic, and targeted imaging technique, has gained significant traction in both research and clinical settings worldwide. Signal-to-noise ratio (SNR) is a crucial factor infl…
View article: Aqueous Extract of Rhubarb Promotes Hepatotoxicity via Facilitating PKM2-Mediated Aerobic Glycolysis in a Rat Model of Diethylnitrosamine-Induced Liver Cancer
Aqueous Extract of Rhubarb Promotes Hepatotoxicity via Facilitating PKM2-Mediated Aerobic Glycolysis in a Rat Model of Diethylnitrosamine-Induced Liver Cancer Open
Aqueous extract of Rhubarb promoted hepatotoxicity via facilitating PKM2-mediated aerobic glycolysis in the rat model of DEN-induced liver cancer.
View article: 3D Microphysiological Tumor Model for Dual-Targeting CAR T Cell Immunotherapy
3D Microphysiological Tumor Model for Dual-Targeting CAR T Cell Immunotherapy Open
The efficiency of immunotherapy stays limited for solid tumors. It is mainly caused by the tumoral structural heterogeneity and its complex microenvironment, which impede the infiltration of immune cells into malignant tissues. Mimicking t…
View article: Aqueous Extract of Rhubarb Promotes Hepatotoxicity Via Facilitating PKM2-Mediated Aerobic Glycolysis in a Rat Model of Diethylnitrosamine-Induced Liver Cancer
Aqueous Extract of Rhubarb Promotes Hepatotoxicity Via Facilitating PKM2-Mediated Aerobic Glycolysis in a Rat Model of Diethylnitrosamine-Induced Liver Cancer Open
View article: Development and testing of a three-period, subsize 2G AIMI MgB<sub>2</sub> planar undulator
Development and testing of a three-period, subsize 2G AIMI MgB<sub>2</sub> planar undulator Open
Compared to Nb 3 Sn- and NbTi-wound superconducting undulators (SCUs), MgB 2 -wound SCUs are of interest for future electron synchrotron beam light sources owing to their higher temperature operating margin and associated stability. In thi…
View article: Functional Role of RING Ubiquitin E3 Ligase VdBre1 and VdHrd1 in the Pathogenicity and Penetration Structure Formation of Verticillium dahliae
Functional Role of RING Ubiquitin E3 Ligase VdBre1 and VdHrd1 in the Pathogenicity and Penetration Structure Formation of Verticillium dahliae Open
Verticillium dahliae, a virulent soil-borne fungus, elicits Verticillium wilt in numerous dicotyledonous plants through intricate pathogenic mechanisms. Ubiquitination, an evolutionarily conserved post-translational modification, marks and…
View article: Elucidating the roles of oxygen defects-rich TiOxNy shell in Ti-based electrocatalyst for enhanced oxygen reduction reaction
Elucidating the roles of oxygen defects-rich TiOxNy shell in Ti-based electrocatalyst for enhanced oxygen reduction reaction Open
View article: Dysbiosis of vaginal and cervical microbiome is associated with uterine fibroids
Dysbiosis of vaginal and cervical microbiome is associated with uterine fibroids Open
Dysbiosis of the female reproductive tract is closely associated with gynecologic diseases. Here, we aim to explore the association between dysbiosis in the genital tract and uterine fibroids (UFs) to further provide new insights into UF e…
View article: Significant reduction in the low-field magnetization of Nb<sub>3</sub>Sn superconducting strands using the internal oxidation APC approach
Significant reduction in the low-field magnetization of Nb<sub>3</sub>Sn superconducting strands using the internal oxidation APC approach Open
Nb 3 Sn superconductors are promising for building accelerator magnets for future energy-frontier circular colliders. A critical factor for this application is the low-field persistent-current magnetization because it leads to several crit…
View article: Gas6/AXL pathway: immunological landscape and therapeutic potential
Gas6/AXL pathway: immunological landscape and therapeutic potential Open
Cancer is a disease with ecological and evolutionary unity, which seriously affects the survival and quality of human beings. Currently, many reports have suggested Gas6 plays an important role in cancer. Binding of gas6 to TAM receptors i…
View article: Recent Progress in Developing Nb<sub>3</sub>Sn Conductors With Increased Specific Heat
Recent Progress in Developing Nb<sub>3</sub>Sn Conductors With Increased Specific Heat Open
A possible approach to reducing Nb3Sn magnet training is to increase the energy margin of Nb3Sn conductors by enhancing their specific heat (Cp). For this study, we have been developing Nb3Sn con…
View article: Alterations in bacterial community dynamics from noncancerous to Gastric cancer
Alterations in bacterial community dynamics from noncancerous to Gastric cancer Open
Gastric microbiome has been shown to contribute to gastric carcinogenesis, understanding how alterations in gastric microbiome is helpful to the prevention and treatment of gastric cancer (GC). However, few studies have focused on the chan…
View article: Superconducting wires and methods of making thereof
Superconducting wires and methods of making thereof Open
Disclosed herein are superconducting wires. The superconducting wires can comprise a metallic matrix and at least one continuous subelement embedded in the matrix. Each subelement can comprise a non-superconducting core, a superconducting …
View article: Kinetics of L-ascorbic acid degradation and non-enzymatic browning development in hot-compressed water
Kinetics of L-ascorbic acid degradation and non-enzymatic browning development in hot-compressed water Open
The effect of reaction conditions, which comprised the reaction temperature (150–190°C), processing time (0.50, 0.75, 1.00, 1.25, 1.50, 2.00, and 2.50 h), pH (5.0, 7.0, and 9.5), and concentration (0.03–0.07 mol/L) of L -ascorbic acid (ASA…
View article: APC Nb<sub>3</sub>Sn superconductors based on internal oxidation of Nb–Ta–Hf alloys
APC Nb<sub>3</sub>Sn superconductors based on internal oxidation of Nb–Ta–Hf alloys Open
In the last few years, a new type of Nb 3 Sn superconducting composite, containing a high density of artificial pinning centers (APC) generated via an internal oxidation approach, has demonstrated a significantly superior performance relat…
View article: Analysis of dynamic change of nutrition status in primary school children of Furong District of Changsha City from 2019 to 2020.
Analysis of dynamic change of nutrition status in primary school children of Furong District of Changsha City from 2019 to 2020. Open
Compared to 2019, the primary school students in Furong District had abnormal nutritional status in 2020. It is necessary to strengthen the management of children's health care to ensure the healthy growth of children.
View article: Integrative cytology and proteome alterations unravel the multitarget effect of a novel alkaloid antofine against<i>Penicillium italicum</i>
Integrative cytology and proteome alterations unravel the multitarget effect of a novel alkaloid antofine against<i>Penicillium italicum</i> Open
Penicillium italicum is the causal agent of citrus blue mold, which is a major threat to the global citrus fruit industry. Antofine, a natural phenanthroindolizidine alkaloid, is water-soluble and exhibits a broad range of biological activ…