Xiubin Li
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View article: Downscaling daily climate data with super-resolution and CMIP6 global climate models to predict the climate in China
Downscaling daily climate data with super-resolution and CMIP6 global climate models to predict the climate in China Open
View article: Integrated bioinformatics analysis reveals novel PANoptosis biomarkers and therapeutic response in clear cell renal cell carcinoma
Integrated bioinformatics analysis reveals novel PANoptosis biomarkers and therapeutic response in clear cell renal cell carcinoma Open
Clear cell renal cell carcinoma (ccRCC) is the most common type of RCC. Apoptosis, pyroptosis, and necroptosis are key regulatory processes in carcinogenesis. Accumulating evidence indicated significant crosstalk among three forms of cell …
View article: RhoJ promotes the progression of clear cell renal cell carcinoma via the TNF-α/NF-κB axis
RhoJ promotes the progression of clear cell renal cell carcinoma via the TNF-α/NF-κB axis Open
Taken together, our findings provide novel insights into the role of RhoJ and identify available potential drugs for controlling ccRCC.
View article: Assessing the Accuracy and Consistency of Cropland Datasets and Their Influencing Factors on the Tibetan Plateau
Assessing the Accuracy and Consistency of Cropland Datasets and Their Influencing Factors on the Tibetan Plateau Open
With advancements in cloud computing and machine learning algorithms, an increasing number of cropland datasets have been developed, including the China land-cover dataset (CLCD) and GlobeLand30 (GLC). The unique climatic conditions of the…
View article: CMIP6-driven 10 km super-resolution daily climate projections with PET estimates in China
CMIP6-driven 10 km super-resolution daily climate projections with PET estimates in China Open
Global warming has intensified extreme weather events, posing challenges to regional climate and hydro-ecological systems. To address the low-resolution limitations of current multi-climate variables and potential evapotranspiration (PET),…
View article: GAMT facilitates tumor progression via inhibiting p53 in clear cell renal cell carcinoma
GAMT facilitates tumor progression via inhibiting p53 in clear cell renal cell carcinoma Open
View article: Cascading impacts of food loss and waste on biodiversity through agricultural land use
Cascading impacts of food loss and waste on biodiversity through agricultural land use Open
View article: How Does Land Fragmentation Affect Agricultural Technical Efficiency? Based on Mediation Effects Analysis
How Does Land Fragmentation Affect Agricultural Technical Efficiency? Based on Mediation Effects Analysis Open
The scientific revelation of the mechanism underlying land fragmentation’s influence on agricultural technical efficiency is extremely important. This study utilized survey data from 305 villages across 12 provinces in Southern China in 20…
View article: T‐cell receptor sequencing reveals hepatocellular carcinoma immune characteristics according to Barcelona Clinic liver cancer stages within liver tissue and peripheral blood
T‐cell receptor sequencing reveals hepatocellular carcinoma immune characteristics according to Barcelona Clinic liver cancer stages within liver tissue and peripheral blood Open
Analysis of T‐cell receptor (TCR) repertoires in different stages of hepatocellular carcinoma (HCC) might help to elucidate its pathogenesis and progression. This study aimed to investigate TCR profiles in liver biopsies and peripheral blo…
View article: Identifying Potent Nonsense-Mediated mRNA Decay Inhibitors with a Novel Screening System
Identifying Potent Nonsense-Mediated mRNA Decay Inhibitors with a Novel Screening System Open
Nonsense-mediated mRNA decay (NMD) is a quality control mechanism that degrades mRNAs carrying a premature termination codon. Its inhibition, alone or in combination with other approaches, could be exploited to develop therapies for geneti…
View article: Analysis of factors influencing terrace abandonment based on unmanned aerial photography and farmer surveys: A case study in Jianhe, Guizhou
Analysis of factors influencing terrace abandonment based on unmanned aerial photography and farmer surveys: A case study in Jianhe, Guizhou Open
Studying the abandonment status of mountain terraces and its determinants, as well as exploring opportunities for the sustainable use of mountain terraces, are of great significance for the protection of regional cultivated land resources.…
View article: Prognostic value and model construction of preoperative inflammatory markers in patients with metastatic renal cell carcinoma
Prognostic value and model construction of preoperative inflammatory markers in patients with metastatic renal cell carcinoma Open
View article: Comprehensive Proteomics Analysis Identifies CD38-Mediated NAD+ Decline Orchestrating Renal Fibrosis in Pediatric Patients With Obstructive Nephropathy
Comprehensive Proteomics Analysis Identifies CD38-Mediated NAD+ Decline Orchestrating Renal Fibrosis in Pediatric Patients With Obstructive Nephropathy Open
Obstructive nephropathy is one of the leading causes of kidney injury and renal fibrosis in pediatric patients. Although considerable advances have been made in understanding the pathophysiology of obstructive nephropathy, most of them wer…
View article: Prevalence of germline mutations in cancer susceptibility genes in Chinese patients with renal cell carcinoma
Prevalence of germline mutations in cancer susceptibility genes in Chinese patients with renal cell carcinoma Open
To our knowledge, this is the first report of pathogenic germline mutations in the FANCI and FANCM genes and heterozygous germline missense mutation in exon 5 of the FH gene c.563A>T:p.N188I in RCC. Young RCC patients,…
View article: Prognostic Value and Model Construction of Preoperative Inflammatory Markers in Patients with Metastatic Renal Cell Carcinoma
Prognostic Value and Model Construction of Preoperative Inflammatory Markers in Patients with Metastatic Renal Cell Carcinoma Open
Purpose: Inflammation is considered to be one of the driving factors of cancer, and chronic inflammation plays a crucial role in tumor growth and metastasis. In this study, the aim was to study the predictive value of preoperative inflamma…
View article: Changes in the Water-Energy Coupling Relationship in Grain Production: A Case Study of the North China Plain
Changes in the Water-Energy Coupling Relationship in Grain Production: A Case Study of the North China Plain Open
Water consumption and energy consumption are inevitable in grain production, but few studies have focused on the integrated assessment of these two indicators and their relationships. To address the research deficiency, taking the North Ch…
View article: Can Livestock Raising Alleviate Farmland Abandonment?—Evidence from China
Can Livestock Raising Alleviate Farmland Abandonment?—Evidence from China Open
Farmland abandonment is a global phenomenon. Changes in socioeconomic factors in China impact the traditional crop–livestock system; however, studies on the relationship between livestock raising and farmland abandonment are insufficient. …
View article: Human infection with a novel reassortment avian influenza A H3N8 virus: an epidemiological investigation study
Human infection with a novel reassortment avian influenza A H3N8 virus: an epidemiological investigation study Open
A four-year-old boy developed recurrent fever and severe pneumonia in April, 2022. High-throughput sequencing on his bronchoalveolar lavage fluid revealed a novel reassortant avian influenza A-H3N8 virus (A/Henan/ZMD-22-2/2022(H3N8). Both …
View article: PRMT5 acts as a tumor suppressor by inhibiting Wnt/β-catenin signaling in murine gastric tumorigenesis
PRMT5 acts as a tumor suppressor by inhibiting Wnt/β-catenin signaling in murine gastric tumorigenesis Open
Previous studies have demonstrated the in vitro oncogenic role of protein arginine methyltransferase 5 (PRMT5) in gastric cancer cell lines. The in vivo function of PRMT5 in gastric tumorigenesis, however, is still unexplored…
View article: A vital option for food security and greenhouse gases mitigation: planting elite super rice in double- to single-rice cropping fields in China
A vital option for food security and greenhouse gases mitigation: planting elite super rice in double- to single-rice cropping fields in China Open
Double-rice cropping (DRC) in southern China has made outstanding contributions to ensuring food security, along with a large amount of greenhouse gas (GHG) emissions. The observed significant shift from double- to single-rice (DtS) croppi…
View article: Spatial differentiation of social security function of cultivated land assets: Comparison of different agricultural regions
Spatial differentiation of social security function of cultivated land assets: Comparison of different agricultural regions Open
View article: Water-Use Efficiency of Crops in the Arid Area of the Middle Reaches of the Heihe River: Taking Zhangye City as an Example
Water-Use Efficiency of Crops in the Arid Area of the Middle Reaches of the Heihe River: Taking Zhangye City as an Example Open
The middle reaches of the Heihe River are an important food base in the arid regions of Northwest China. The agricultural water consumption in this region accounts for about 90% of the total water consumption. The shortage of water resourc…
View article: Exploring a Moderate Operation Scale in China’s Grain Production: A Perspective on the Costs of Machinery Services
Exploring a Moderate Operation Scale in China’s Grain Production: A Perspective on the Costs of Machinery Services Open
Due to the indivisibility of agricultural machinery in production, limited farm sizes have reduced mechanization efficiency and increased the cost of grain production in China. As a result, the development of a moderate-scale farming syste…
View article: Characteristics of cropland fragmentation and its impact on agricultural production costs in mountainous areas
Characteristics of cropland fragmentation and its impact on agricultural production costs in mountainous areas Open
View article: 山区土地流转过程中的零租金现象及其解释——基于交易费用的视角
山区土地流转过程中的零租金现象及其解释——基于交易费用的视角 Open
View article: Effects of Bailing capsule on diabetic nephropathy based on UPLC-MS urine metabolomics
Effects of Bailing capsule on diabetic nephropathy based on UPLC-MS urine metabolomics Open
UPLC-MS-based metabolomics along with pattern recognition was applied to explore the metabolic alteration of diabetic nephropathy and therapeutic mechanisms of Bailing capsule.
View article: Decreasing Rice Cropping Intensity in Southern China from 1990 to 2015
Decreasing Rice Cropping Intensity in Southern China from 1990 to 2015 Open
Assessing changes in rice cropping systems is essential for ensuring food security, greenhouse gas emissions, and sustainable water management. However, due to the insufficient availability of images with moderate to high spatial resolutio…
View article: E-cadherin is Required for the Homeostasis of Lgr5<sup>+</sup> Gastric Antral Stem Cells
E-cadherin is Required for the Homeostasis of Lgr5<sup>+</sup> Gastric Antral Stem Cells Open
Lgr5-expressing stem cells contribute to the epithelial turnover of the gastric antrum. However, the mechanism controlling the homeostasis of Lgr5+ antral stem cells is not fully understood. Here, we demonstrate the key role of …
View article: Irrigation Water Availability and Winter Wheat Abandonment in the North China Plain (NCP): Findings from a Case Study in Cangxian County of Hebei Province
Irrigation Water Availability and Winter Wheat Abandonment in the North China Plain (NCP): Findings from a Case Study in Cangxian County of Hebei Province Open
The North China Plain (NCP) is the major winter wheat producing area in China. Abandonment of this crop has, however, become more and more prevalent in this region since the late 1990s. Although the underlying causes of this phenomenon rem…
View article: 中国土地流转的时空演变特征及影响因素研究
中国土地流转的时空演变特征及影响因素研究 Open
摘要: 为了在全国尺度上全面了解中国的土地流转发展状况及其影响因素,论文在详细分析中国土地流转时空演变特征的基础上,利用因子分析方法在省级尺度对影响土地流转的因素进行了归纳和提取。结果表明:1)当前中国土地流转发展迅速,2007—2015年,中国土地流转率由5.2%增至33.3%。但土地流转程度区域差异明显,南部与西部地区流转较慢,规模较小,平原地区流转较快,规模较大。2)土地流转对规模经营(经营规模>3.33 hm2)的促进效果尚不明显,中国规模经营比例仍然偏低,经营规模…