Xiufang Kong
YOU?
Author Swipe
View article: Sex differences in the associations between prior weight loss and all-cause or cardiovascular mortality in non-elderly individuals with hyperuricemia: a mortality follow-up study
Sex differences in the associations between prior weight loss and all-cause or cardiovascular mortality in non-elderly individuals with hyperuricemia: a mortality follow-up study Open
Prior LTWL ≥ 5% was associated with increased all-cause and CVD mortality in US non-elderly female participants with hyperuricemia. Additional prospective and longitudinal randomized clinical trials are necessary to further examine the cur…
View article: Predictors of irreversible renal dysfunction in patients with idiopathic retroperitoneal fibrosis
Predictors of irreversible renal dysfunction in patients with idiopathic retroperitoneal fibrosis Open
Objectives Idiopathic retroperitoneal fibrosis (iRPF) can lead to irreversible kidney damage. This study aimed to investigate predictors of irreversible renal dysfunction in patients with iRPF. Methods Eighty-three patients with newly diag…
View article: Coronavirus disease 2019 vaccination in patients with rheumatic diseases: A bibliometric‐based analysis of trends
Coronavirus disease 2019 vaccination in patients with rheumatic diseases: A bibliometric‐based analysis of trends Open
Background Coronavirus disease 2019 (COVID‐19) vaccination in patients with rheumatic disease is of practical clinical importance. This study aimed to perform a comprehensive bibliometric analysis of COVID‐19 vaccination in patients with r…
View article: SERPINA3, FGA, AGP1, ITIH3 and SAA1 as novel biomarkers for eosinophilic granulomatosis with polyangiitis diagnosis and activity assessment
SERPINA3, FGA, AGP1, ITIH3 and SAA1 as novel biomarkers for eosinophilic granulomatosis with polyangiitis diagnosis and activity assessment Open
Objective The objective of this study was to identify novel biomarkers for diagnosis and prediction of active eosinophilic granulomatosis with polyangiitis (EGPA) through data-independent acquisition (DIA) analysis. Methods Plasma samples …
View article: COVID-19 infection characteristics, risk factors and its potential impacts on Takayasu arteritis: a web-based survey in a large cohort
COVID-19 infection characteristics, risk factors and its potential impacts on Takayasu arteritis: a web-based survey in a large cohort Open
Objectives To investigate the characteristics of COVID-19 and its impact on patients with Takayasu’s arteritis (TAK). Methods A web-based survey was administered to a TAK cohort and their co-residents in China during January 2023. Infectio…
View article: Transmission infrared micro-spectroscopic study of individual human hair
Transmission infrared micro-spectroscopic study of individual human hair Open
Our work implies that the variation of spectral weight may relate to the disordered microscopic structure variation of the hair cortex during an inflammatory attack. Our work reveals the potential of hair infrared transmission spectrum in …
View article: Transmission infrared micro-spectroscopic study of individual human hair
Transmission infrared micro-spectroscopic study of individual human hair Open
Understanding the optical transmission property of human hair, especially in the infrared regime, is vital in physical, clinical, and biomedical research. However, the majority of infrared spectroscopy on human hair is performed in the ref…
View article: Single-Cell RNA-Sequencing Reveals Peripheral T Helper Cells Promoting the Development of IgG4-Related Disease by Enhancing B Cell Activation and Differentiation
Single-Cell RNA-Sequencing Reveals Peripheral T Helper Cells Promoting the Development of IgG4-Related Disease by Enhancing B Cell Activation and Differentiation Open
Abnormal B cell differentiation plays a critical role in IgG4-related disease (IgG4-RD), but the underlying mechanism remains largely unknown. We investigated the cell landscape from three IgG4-RD retroperitoneal tissues and three control …
View article: COVID-19 vaccine uptake, hesitancy and clinical effects on patients with Takayasu’s arteritis: A web-based questionnaire survey from a large cohort
COVID-19 vaccine uptake, hesitancy and clinical effects on patients with Takayasu’s arteritis: A web-based questionnaire survey from a large cohort Open
Objective This study aimed to investigate the Coronavirus disease 2019 (COVID-19) vaccination rate, reasons for vaccine hesitancy and clinical effects on patients with Takayasu’s arteritis (TAK). Methods A web-based survey was administered…
View article: Comparison of the efficacy and safety of leflunomide versus placebo combined with basic prednisone therapy in patients with active disease phase of Takayasu arteritis: study protocol for a randomized, double-blinded controlled trial (Takayasu arteritis clinical trial in China: TACTIC)
Comparison of the efficacy and safety of leflunomide versus placebo combined with basic prednisone therapy in patients with active disease phase of Takayasu arteritis: study protocol for a randomized, double-blinded controlled trial (Takayasu arteritis clinical trial in China: TACTIC) Open
Background: Takayasu arteritis (TAK) is an immune-induced granulomatous vasculitis that occurs primarily in young Asian women. Our previous cohort studies have indicated that leflunomide (LEF), which can lead to rapid induction and might b…
View article: Curcumin alleviates inflammation in Takayasu's arteritis by blocking CCL2 overexpression in adventitial fibroblasts
Curcumin alleviates inflammation in Takayasu's arteritis by blocking CCL2 overexpression in adventitial fibroblasts Open
Curcumin alleviated inflammation in TAK by downregulating CCL2 overexpression in AAFs through inhibiting the JAK2/AKT/STAT3 signalling pathway.
View article: Potential Role of Macrophage Phenotypes and CCL2 in the Pathogenesis of Takayasu Arteritis
Potential Role of Macrophage Phenotypes and CCL2 in the Pathogenesis of Takayasu Arteritis Open
Objectives To investigate vascular macrophage phenotype as well as vascular and peripheral chemokine (C-C motif) ligand 2 (CCL2) expression during different stages of disease progression in patients with Takayasu Arteritis (TA). Methods In…
View article: Identification of susceptibility loci for Takayasu arteritis through a large multi-ancestral genome-wide association study
Identification of susceptibility loci for Takayasu arteritis through a large multi-ancestral genome-wide association study Open
Takayasu arteritis is a rare inflammatory disease of large arteries. We performed a genetic study in Takayasu arteritis comprising 6,670 individuals (1,226 affected individuals) from five different populations. We discovered HLA risk facto…
View article: Therapeutic value of curcumin on the initiation and development of inflammation in Takayasu’s arteritis mediated by HSP65-induced CCL2 overexpression
Therapeutic value of curcumin on the initiation and development of inflammation in Takayasu’s arteritis mediated by HSP65-induced CCL2 overexpression Open
Background Takayasu’s arteritis (TAK) is a chronic inflammatory disease characterized by macrophage infiltration. During the active stage, aorta adventitial fibroblasts (AAFs) proliferate excessively and produce numerous pro-inflammatory f…
View article: Involvement of the pulmonary arteries in patients with Takayasu arteritis: a prospective study from a single center in China
Involvement of the pulmonary arteries in patients with Takayasu arteritis: a prospective study from a single center in China Open
Background: Takayasu arteritis (TA) is a large-vessel vasculitis that can involve pulmonary arteries (PAs). We studied multiple clinical characteristics related to pulmonary artery involvement (PAI) in TA patients. Methods: We enrolled 216…
View article: Involvement of the pulmonary arteries in patients with Takayasu arteritis
Involvement of the pulmonary arteries in patients with Takayasu arteritis Open
Background: Takayasu arteritis (TA) is a large-vessel vasculitis that can involve pulmonary arteries (PAs). We studied multiple clinical characteristics related to pulmonary artery involvement (PAI) in TA patients. Methods: We enrolled 216…
View article: Clinical characteristics and potential biomarkers for disease activity of patients with ANCA associated vasculitis: a monocenter study in China
Clinical characteristics and potential biomarkers for disease activity of patients with ANCA associated vasculitis: a monocenter study in China Open
Objective: The aim of this study was to describe the clinical and serological features of patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) in eastern China using data from a hospital-based study. And loo…
View article: Serum leptin, a potential predictor of long‐term angiographic progression in Takayasu’s arteritis
Serum leptin, a potential predictor of long‐term angiographic progression in Takayasu’s arteritis Open
Aim In patients with Takayasu's arteritis (TA), current biomarkers that properly reflect the progression of the vascular structure remain absent. We aimed to determine the serum leptin level to investigate its relationship with imaging cha…
View article: Multi-disease associated risk locus in<i>IL6</i>represses the anti-inflammatory gene<i>GPNMB</i>through chromatin looping and recruiting MEF2-HDAC complex
Multi-disease associated risk locus in<i>IL6</i>represses the anti-inflammatory gene<i>GPNMB</i>through chromatin looping and recruiting MEF2-HDAC complex Open
We have previously revealed a genetic association between Takayasu arteritis and a non-coding genetic variant in an enhancer region within IL6 (rs2069837 A/G). The risk allele in this variant (allele A) has a protective effect against chro…
View article: 200. PERIPHERAL BLOOD CHEMOKINE PROFILE IN TAKAYASU ARTERITIS
200. PERIPHERAL BLOOD CHEMOKINE PROFILE IN TAKAYASU ARTERITIS Open
Background: Low density granulocyte (LDG), a proinflammatory population of neutrophils, was first described in systemic lupus erythematosus (SLE) and has been shown to contribute to lupus pathogenesis.It has been suggested that LDGs have a…