Xiujuan Zheng
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View article: CD33 <sup>KO</sup> -CD33-mesothelin Loop CAR design avoids fratricide and improves efficacy of iNK cells against acute myeloid leukemia
CD33 <sup>KO</sup> -CD33-mesothelin Loop CAR design avoids fratricide and improves efficacy of iNK cells against acute myeloid leukemia Open
Background Patients with acute myeloid leukemia (AML) are often older, which brings challenges of endurance and persistent efficacy of autologous chimeric antigen receptor (CAR)-T cell therapies. Allogenic CAR-natural killer (NK) cell ther…
View article: Engineered CRO-CD7 CAR-NK cells derived from pluripotent stem cells avoid fratricide and efficiently suppress human T-cell malignancies
Engineered CRO-CD7 CAR-NK cells derived from pluripotent stem cells avoid fratricide and efficiently suppress human T-cell malignancies Open
View article: HP-YOLO: A Lightweight Real-Time Human Pose Estimation Method
HP-YOLO: A Lightweight Real-Time Human Pose Estimation Method Open
Human Pose Estimation (HPE) plays a critical role in medical applications, particularly within nursing robotics for patient monitoring. Despite its importance, HPE faces several challenges, including high rates of false positives and negat…
View article: Estimation of heart rate and respiratory rate by fore-background spatiotemporal modeling of videos
Estimation of heart rate and respiratory rate by fore-background spatiotemporal modeling of videos Open
Heart rate (HR) and respiratory rate (RR) are two critical physiological parameters that can be estimated from video recordings. However, the accuracy of remote estimation of HR and RR is affected by fluctuations in ambient illumination. T…
View article: MFF-Net: A Lightweight Multi-Frequency Network for Measuring Heart Rhythm from Facial Videos
MFF-Net: A Lightweight Multi-Frequency Network for Measuring Heart Rhythm from Facial Videos Open
Remote photo-plethysmography (rPPG) is a useful camera-based health motioning method that can measure the heart rhythm from facial videos. Many well-established deep learning models can provide highly accurate and robust results in measuri…
View article: Hypoimmunogenic CD19 CAR-NK cells derived from embryonic stem cells suppress the progression of human B-cell malignancies in xenograft animals
Hypoimmunogenic CD19 CAR-NK cells derived from embryonic stem cells suppress the progression of human B-cell malignancies in xenograft animals Open
Background Chimeric antigen receptor (CAR) engineered natural killer (NK) cells exhibit advantages such as MHC-independent recognition and strong anti-tumor functions. However, allogeneic CAR-NK cells derived from human tissues are heterog…
View article: [Visual field prediction based on temporal-spatial feature learning].
[Visual field prediction based on temporal-spatial feature learning]. Open
Glaucoma stands as the leading irreversible cause of blindness worldwide. Regular visual field examinations play a crucial role in both diagnosing and treating glaucoma. Predicting future visual field changes can assist clinicians in makin…
View article: Efficient generation of CAR NK cells from human umbilical cord blood CD34<sup>+</sup>stem and progenitors for democratizing affordable immunotherapy
Efficient generation of CAR NK cells from human umbilical cord blood CD34<sup>+</sup>stem and progenitors for democratizing affordable immunotherapy Open
Chimeric antigen receptor (CAR) natural killer cells (CAR NK) cells, leveraging safety and not requiring HLA match in adoptive infusion, have emerged as promising alternative cells to CAR-T cells for immunotherapies. High and multiple dose…
View article: FreeGaze: A Framework for 3D Gaze Estimation Using Appearance Cues from a Facial Video
FreeGaze: A Framework for 3D Gaze Estimation Using Appearance Cues from a Facial Video Open
Gaze is a significant behavioral characteristic that can be used to reflect a person’s attention. In recent years, there has been a growing interest in estimating gaze from facial videos. However, gaze estimation remains a challenging prob…
View article: Prior knowledge-based residuals shrinkage prototype networks for cross-domain fault diagnosis
Prior knowledge-based residuals shrinkage prototype networks for cross-domain fault diagnosis Open
In engineering practice, device failure samples are limited in the case of unexpected catastrophic faults, thereby limiting the application of deep learning in fault diagnosis. In this study, we propose a prior knowledge-based residual shr…
View article: COST-EFFECTIVE CAMERA LOCALIZATION AIDED BY PRIOR POINT CLOUDS MAPS FOR LEVEL 3 AUTONOMOUS DRIVING VEHICLES
COST-EFFECTIVE CAMERA LOCALIZATION AIDED BY PRIOR POINT CLOUDS MAPS FOR LEVEL 3 AUTONOMOUS DRIVING VEHICLES Open
Precise and robust localization is critical for many navigation tasks, especially autonomous driving systems. The most popular localization approach is global navigation satellite systems (GNSS). However, it has several shortcomings such a…
View article: Remote Blood Pressure Estimation via the Spatiotemporal Mapping of Facial Videos
Remote Blood Pressure Estimation via the Spatiotemporal Mapping of Facial Videos Open
Blood pressure (BP) monitoring is vital in daily healthcare, especially for cardiovascular diseases. However, BP values are mainly acquired through a contact-sensing method, which is inconvenient and unfriendly for BP monitoring. This pape…
View article: Adaptive Predefined-Time Sliding Mode Control for QUADROTOR Formation with Obstacle and Inter-Quadrotor Avoidance
Adaptive Predefined-Time Sliding Mode Control for QUADROTOR Formation with Obstacle and Inter-Quadrotor Avoidance Open
In this paper, aiming at the problem of control and obstacle avoidance in quadrotor formation when mathematical modeling is not accurate, the artificial potential field method with virtual force is used to plan the obstacle avoidance path …
View article: Author Correction: Lateral plate mesoderm cell-based organoid system for NK cell regeneration from human pluripotent stem cells
Author Correction: Lateral plate mesoderm cell-based organoid system for NK cell regeneration from human pluripotent stem cells Open
View article: Lateral plate mesoderm cell-based organoid system for NK cell regeneration from human pluripotent stem cells
Lateral plate mesoderm cell-based organoid system for NK cell regeneration from human pluripotent stem cells Open
View article: [Analysis of Characteristic Eye Movement Behaviors of Young Adults with Different Degrees of Myopia].
[Analysis of Characteristic Eye Movement Behaviors of Young Adults with Different Degrees of Myopia]. Open
For young adult myopic patients, the longer the AL is, the higher the degree of the myopia and the worse the fixation stability becomes. The fixation stability of patients with high myopia was significantly worse than that of patients with…
View article: [A Gaussian mixture-hidden Markov model of human visual behavior].
[A Gaussian mixture-hidden Markov model of human visual behavior]. Open
Vision is an important way for human beings to interact with the outside world and obtain information. In order to research human visual behavior under different conditions, this paper uses a Gaussian mixture-hidden Markov model (GMM-HMM) …
View article: [Joint optic disc and cup segmentation based on residual multi-scale fully convolutional neural network].
[Joint optic disc and cup segmentation based on residual multi-scale fully convolutional neural network]. Open
Glaucoma is the leading cause of irreversible blindness, but its early symptoms are not obvious and are easily overlooked, so early screening for glaucoma is particularly important. The cup to disc ratio is an important indicator for clini…
View article: Detection of Depression and Its High-Risk Group using Scanpath Comparison Based on Semantic Information
Detection of Depression and Its High-Risk Group using Scanpath Comparison Based on Semantic Information Open
Background: Depression is a burdensome, recurring mental health disorder with high prevalence. The traditional detection of depression relies on structured interviews and questionnaires, which is labor-intensive and time-consuming. Also, t…
View article: A Unified Framework to Integrate SPECT Perfusion Imaging with Dose-volume Metrics for Estimation of Radiation Pneumonitis
A Unified Framework to Integrate SPECT Perfusion Imaging with Dose-volume Metrics for Estimation of Radiation Pneumonitis Open
Background: Single photon emission computed tomography (SPECT) images provides functional information in both diagnosis and radiation therapy. This study aimed to evaluate a unified framework of different approaches and find the optimal on…
View article: Automatic Recognition of Laryngoscopic Images Using a Deep‐Learning Technique
Automatic Recognition of Laryngoscopic Images Using a Deep‐Learning Technique Open
Objectives/Hypothesis To develop a deep‐learning–based computer‐aided diagnosis system for distinguishing laryngeal neoplasms (benign, precancerous lesions, and cancer) and improve the clinician‐based accuracy of diagnostic assessments of …
View article: A Deep Learning Method for Short-Term Residential Load Forecasting in Smart Grid
A Deep Learning Method for Short-Term Residential Load Forecasting in Smart Grid Open
Residential demand response is vital for the efficiency of power system. It has attracted much attention from both academic and industry in recent years. Accurate short-term load forecasting is a fundamental task for demand response. While…
View article: A Graphical Authentication System Controlled by Eye Movement
A Graphical Authentication System Controlled by Eye Movement Open
Graphical password is a potential alternative to the traditional alphanumerical password due to its advantages of recognition and memory in the security system. Eye movement, a natural interaction modality, is a promising tool to replace t…
View article: [A computer tomography assisted method for the automatic detection of region of interest in dynamic kidney images].
[A computer tomography assisted method for the automatic detection of region of interest in dynamic kidney images]. Open
Glomerular filtration rate (GFR), which can be estimated by Gates method with dynamic kidney single photon emission computed tomography (SPECT) imaging, is a key indicator of renal function. In this paper, an automatic computer tomography …
View article: A Computer-Aided Analysis Method of SPECT Brain Images for Quantitative Treatment Monitoring: Performance Evaluations and Clinical Applications
A Computer-Aided Analysis Method of SPECT Brain Images for Quantitative Treatment Monitoring: Performance Evaluations and Clinical Applications Open
The objective and quantitative analysis of longitudinal single photon emission computed tomography (SPECT) images are significant for the treatment monitoring of brain disorders. Therefore, a computer aided analysis (CAA) method is introdu…
View article: Cerebral blood perfusion changes in amputees with myoelectric hands after rehabilitation: a SPECT computer-aided analysis
Cerebral blood perfusion changes in amputees with myoelectric hands after rehabilitation: a SPECT computer-aided analysis Open
Our study demonstrated that the CBF SPECT-CA method can detect the brain blood perfusion changes induced by rehabilitation with high sensitivity and accuracy. This method has great potential for locating the remodeled neuron regions of amp…
View article: MOESM3 of Cerebral blood perfusion changes in amputees with myoelectric hands after rehabilitation: a SPECT computer-aided analysis
MOESM3 of Cerebral blood perfusion changes in amputees with myoelectric hands after rehabilitation: a SPECT computer-aided analysis Open
Additional file 3. The activated regions of the five participants.
View article: Dynamic FDG-PET Imaging to Differentiate Malignancies from Inflammation in Subcutaneous and In Situ Mouse Model for Non-Small Cell Lung Carcinoma (NSCLC)
Dynamic FDG-PET Imaging to Differentiate Malignancies from Inflammation in Subcutaneous and In Situ Mouse Model for Non-Small Cell Lung Carcinoma (NSCLC) Open
In contrast to static PET based SUVmax, both subcutaneous and in situ inflammations and malignancies can be differentiated via dynamic FDG-PET based Ki. Moreover, Values of influx rate constant Ki from compartmental modeling can offer an a…