Xiulian Yu
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View article: Molecular architecture of coronavirus double-membrane vesicle pore complex
Molecular architecture of coronavirus double-membrane vesicle pore complex Open
View article: <scp>Cryo‐EM</scp> structures of perforin‐2 in isolation and assembled on a membrane suggest a mechanism for pore formation
<span>Cryo‐EM</span> structures of perforin‐2 in isolation and assembled on a membrane suggest a mechanism for pore formation Open
Perforin‐2 (PFN2, MPEG1) is a key pore‐forming protein in mammalian innate immunity restricting intracellular bacteria proliferation. It forms a membrane‐bound pre‐pore complex that converts to a pore‐forming structure upon acidification; …
View article: Perforin-2 clockwise hand-over-hand pre-pore to pore transition mechanism
Perforin-2 clockwise hand-over-hand pre-pore to pore transition mechanism Open
View article: Structure and assembly of cargo Rubisco in two native α-carboxysomes
Structure and assembly of cargo Rubisco in two native α-carboxysomes Open
View article: Structures of perforin-2 in solution and on a membrane reveal mechanisms for pore formation
Structures of perforin-2 in solution and on a membrane reveal mechanisms for pore formation Open
Perforin-2 (PFN2, MPEG1) is a key pore-forming protein in mammalian innate immunity restricting intracellular bacteria proliferation. It forms a membrane-bound pre-pore complex that converts to a pore-forming structure upon acidification; …
View article: Structural, Functional and Computational Studies of Membrane Recognition by Plasmodium Perforin-Like Proteins 1 and 2
Structural, Functional and Computational Studies of Membrane Recognition by Plasmodium Perforin-Like Proteins 1 and 2 Open
Perforin-like proteins (PLPs) play key roles in mechanisms associated with parasitic disease caused by the apicomplexan parasites Plasmodium and Toxoplasma. The T. gondii PLP1 (TgPLP1) mediates tachyzoite egress from cells, while the five …
View article: Tales of Two α-Carboxysomes: the Structure and Assembly of Cargo Rubisco
Tales of Two α-Carboxysomes: the Structure and Assembly of Cargo Rubisco Open
Carboxysomes are a family of bacterial microcompartments in cyanobacteria and chemoautotrophs. It encapsulates carbonic anhydrase and Ribulose 1,5-bisphosphate carboxylase/oxygenase (Rubisco) catalysing carbon fixation inside a proteinaceo…
View article: Structural, functional and computational studies of membrane recognition by Plasmodium Perforin-Like Proteins 1 and 2
Structural, functional and computational studies of membrane recognition by Plasmodium Perforin-Like Proteins 1 and 2 Open
Perforin-like proteins (PLPs) play key roles in the mechanisms associated with parasitic disease caused by apicomplexans such as Plasmodium (malaria) and Toxoplasma . The T. gondii PLP1 (TgPLP1) mediates tachyzoite egress from cells, while…
View article: An integrated analysis of cell-type specific gene expression reveals genes regulated by REVOLUTA and KANADI1 in the Arabidopsis shoot apical meristem
An integrated analysis of cell-type specific gene expression reveals genes regulated by REVOLUTA and KANADI1 in the Arabidopsis shoot apical meristem Open
In the Arabidopsis thaliana shoot apical meristem (SAM) the expression domains of Class III Homeodomain Leucine Zipper (HD-ZIPIII) and KANADI (KAN) genes are separated by a narrow boundary region from which new organs are initiated. Disrup…
View article: Description of clusters identified in cell-type profiling (Fig 1I).
Description of clusters identified in cell-type profiling (Fig 1I). Open
View article: Structure and mechanism of bactericidal mammalian perforin-2, an ancient agent of innate immunity
Structure and mechanism of bactericidal mammalian perforin-2, an ancient agent of innate immunity Open
Bactericidal perforin-2 assembles an inactivated pre-pore complex and undergoes a 180° reconfiguration for membrane attack.
View article: Cell type boundaries organize plant development
Cell type boundaries organize plant development Open
In plants the dorsoventral boundary of leaves defines an axis of symmetry through the centre of the organ separating the top (dorsal) and bottom (ventral) tissues. Although the positioning of this boundary is critical for leaf morphogenesi…
View article: Author response: Cell type boundaries organize plant development
Author response: Cell type boundaries organize plant development Open
View article: The role of dorsoventral cell type boundaries in controlling Arabidopsis leaf development
The role of dorsoventral cell type boundaries in controlling Arabidopsis leaf development Open
An important developmental mechanism utilized by metazoans is the establishment of specialized cells, or organizers that act to pattern tissues in a non-cell autonomous manner. In plants, for which multicellularity evolved independently, t…