Xiuwen Lan
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View article: Single‐Cell RNA Sequencing Reveals Granzyme K <sup>+</sup> CD8 <sup>+</sup> T Cells as a Target for Mitigating Plaque Instability Following Radiation
Single‐Cell RNA Sequencing Reveals Granzyme K <sup>+</sup> CD8 <sup>+</sup> T Cells as a Target for Mitigating Plaque Instability Following Radiation Open
Background Cardiac issues following radiotherapy are increasingly prevalent among patients with thoracic cancer and coronary disease. However, the mechanisms underlying radiotherapy‐induced plaque instability and changes in plaque characte…
View article: Case report: a critically ill patient with aggressive NK-cell leukemia receiving emergency chemotherapy in the ICU
Case report: a critically ill patient with aggressive NK-cell leukemia receiving emergency chemotherapy in the ICU Open
Aggressive NK-cell leukemia (ANKL) is a scarce mature NK-cell neoplasm frequently associated with Epstein-Barr virus (EBV) infection. We report the case of a 47-year-old male patient who was admitted to the hospital due to recurrent fever,…
View article: Case report: a critically ill patient with aggressive NK-cell leukemia receiving emergency chemotherapy in the ICU
Case report: a critically ill patient with aggressive NK-cell leukemia receiving emergency chemotherapy in the ICU Open
Aggressive NK-cell leukemia (ANKL) is a scarce mature NK-cell neoplasm frequently associated with Epstein-Barr virus (EBV) infection. We report the case of a 47-year-old male patient who was admitted to the hospital due to recurrent fever,…
View article: Comprehensive analysis of karyopherin alpha family expression in lung adenocarcinoma: Association with prognostic value and immune homeostasis
Comprehensive analysis of karyopherin alpha family expression in lung adenocarcinoma: Association with prognostic value and immune homeostasis Open
Background: Karyopherin alpha (KPNA), a nuclear transporter, has been implicated in the development as well as the progression of many types of malignancies. Immune homeostasis is a multilevel system which regulated by multiple factors. Ho…
View article: Cytokine levels in sputum, not serum, may be more helpful for indicating the damage in the lung and the prognosis of severe COVID-19 – A case series
Cytokine levels in sputum, not serum, may be more helpful for indicating the damage in the lung and the prognosis of severe COVID-19 – A case series Open
View article: Absence of Txnrd3 and its Interact Protein Anxa2 Promotes the Process of Liver Fibrosis and Development of Liver Cancer
Absence of Txnrd3 and its Interact Protein Anxa2 Promotes the Process of Liver Fibrosis and Development of Liver Cancer Open
View article: Cytokine Levels in the Body Fluids of a Patient With COVID-19 and Acute Respiratory Distress Syndrome: A Case Report
Cytokine Levels in the Body Fluids of a Patient With COVID-19 and Acute Respiratory Distress Syndrome: A Case Report Open
Background: Some patients with coronavirus disease 2019 progress rapidly to acute respiratory distress syndrome (ARDS), septic shock, and multiple organ failure (1).Some experts attribute this sequence of events to a large increase in cyto…
View article: Correction to: Tumor-associated neutrophils induce EMT by IL-17a to promote migration and invasion in gastric cancer cells
Correction to: Tumor-associated neutrophils induce EMT by IL-17a to promote migration and invasion in gastric cancer cells Open
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View article: Tumor-associated neutrophils induce EMT by IL-17a to promote migration and invasion in gastric cancer cells
Tumor-associated neutrophils induce EMT by IL-17a to promote migration and invasion in gastric cancer cells Open
View article: Systemic Inflammation Response Index (SIRI), cancer stem cells and survival of localised gastric adenocarcinoma after curative resection
Systemic Inflammation Response Index (SIRI), cancer stem cells and survival of localised gastric adenocarcinoma after curative resection Open
View article: Addition of peritonectomy to gastrectomy can predict good prognosis of gastric adenocarcinoma patients with intraoperatively proven single P1/P2 carcinomatosis
Addition of peritonectomy to gastrectomy can predict good prognosis of gastric adenocarcinoma patients with intraoperatively proven single P1/P2 carcinomatosis Open
This study was to evaluate the prognosis of peritonectomy following gastrectomy for gastric adenocarcinoma patients with intraoperatively proven single P1/P2 carcinomatosis and to define the best therapeutic strategy of the patient cohort.…
View article: Derived neutrophil to lymphocyte ratio and monocyte to lymphocyte ratio may be better biomarkers for predicting overall survival of patients with advanced gastric cancer
Derived neutrophil to lymphocyte ratio and monocyte to lymphocyte ratio may be better biomarkers for predicting overall survival of patients with advanced gastric cancer Open
Although preoperative NLR, dNLR, MLR, PLR, and PNI in peripheral blood proved significant prediction of prognoses of postoperative GC patients, dNLR and MLR may be better biomarkers for predicting overall survival, especially in advanced G…
View article: Relationships of MMP-9, E-cadherin, and VEGF expression with clinicopathological features and response to chemosensitivity in gastric cancer
Relationships of MMP-9, E-cadherin, and VEGF expression with clinicopathological features and response to chemosensitivity in gastric cancer Open
The matrix metalloproteinase-9, E-cadherin, and vascular endothelial growth factor play an important role in behavior of tumor cell growth, invasion, and metastasis. In this study, we investigated the relationships of matrix metalloprotein…
View article: Downregulation of Notch1 inhibits the invasion and metastasis of human gastric cancer cells SGC7901 and MKN74 in vitro through PTEN activation and dephosphorylation of Akt and FAK
Downregulation of Notch1 inhibits the invasion and metastasis of human gastric cancer cells SGC7901 and MKN74 in vitro through PTEN activation and dephosphorylation of Akt and FAK Open
Migration and invasion are both vital causes of mortality in patients with gastric cancer. Therefore, the inhibition of these tumour cell processes is of great importance in gastric cancer therapy. Activation of Notch has been reported in …
View article: Increased BTLA and HVEM in gastric cancer are associated with progression and poor prognosis
Increased BTLA and HVEM in gastric cancer are associated with progression and poor prognosis Open
The increased BTLA and HVEM levels correlate with the development and poor prognosis of gastric cancer. HVEM is an important prognostic indicator, and BTLA/HVEM pathway is considered to be a promising candidate for immunotherapy of gastric…
View article: Elevated HABP1 protein expression correlates with progression and poor survival in patients with gastric cancer
Elevated HABP1 protein expression correlates with progression and poor survival in patients with gastric cancer Open
These findings demonstrated that HABP1 was an indicator for GC progression and poor survival, which highlighted its potential role as a therapeutic target for GCs.