Wenxuan Zhang
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View article: The Therapeutic Effect of Group Exercise on Depression Patients With and Without Comorbid Anxiety Symptoms A Secondary Data Analysis
The Therapeutic Effect of Group Exercise on Depression Patients With and Without Comorbid Anxiety Symptoms A Secondary Data Analysis Open
Background Anxious major depressive disorder (aMDD) has worse outcomes. Exercise's effect on aMDD is uncertain. This study explores whether exercise benefits patients with depression accompanied by anxiety. Methods This is a post hoc analy…
View article: A review of studies on the impact of social isolation and loneliness on Alzheimer's disease
A review of studies on the impact of social isolation and loneliness on Alzheimer's disease Open
Alzheimer's disease (AD), the most common neurodegenerative disease affecting the elderly, is on a continuous global rise in incidence and prevalence, placing a heavy burden on the individual, the family, and society. In recent years, more…
View article: Mandibular Advancement In Class-Ii Case: 3-Year Follow-Up
Mandibular Advancement In Class-Ii Case: 3-Year Follow-Up Open
Introduction: Clear aligner-based Mandibular Advancement (MA) is a reliable procedure for adolescent patients with mandibular retrognathia. This case report presents the orthodontic management and 3-year follow-up of a patient with skeleta…
View article: Skeletal Class II Hyperdivergent Patient Treated With Clear Aligners
Skeletal Class II Hyperdivergent Patient Treated With Clear Aligners Open
Introduction: Clear aligners has become one of the mainstream techniques in modern orthodontic treatment. This case report presents an adult patient with a skeletal Class II hyperdivergent malocclusion treated with clear aligners. Case des…
View article: Genome-wide identification and transcriptomic analysis of the MAPK family provides insights into the molecular basis of disease resistance of postharvest eggplant in response to Botrytis cinerea
Genome-wide identification and transcriptomic analysis of the MAPK family provides insights into the molecular basis of disease resistance of postharvest eggplant in response to Botrytis cinerea Open
Eggplant ( Solanum melongena ), an important crop for food supply, can suffer from severe gray mold rot caused by Botrytis cinerea , resulting in huge postharvest damage every year. Mitogen-activated protein kinase (MAPK) cascades, importa…
View article: The relationship between self-efficacy/resilience and the mental health status of hemodialysis nurses: multiple mediation effects of insomnia and fatigue
The relationship between self-efficacy/resilience and the mental health status of hemodialysis nurses: multiple mediation effects of insomnia and fatigue Open
Background and purpose Due to the high frequency of hemodialysis treatment, hemodialysis nurses have to bear a lot of psychological pressure, which makes them more vulnerable to anxiety and depression. This study aims to explore the relati…
View article: Inflammatory Indices are Associated with Non-Suicidal Self-Injury in Adolescents with Major Depressive Disorder
Inflammatory Indices are Associated with Non-Suicidal Self-Injury in Adolescents with Major Depressive Disorder Open
Background. The neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), platelet-lymphocyte ratio (PLR), and C-reactive protein (CRP)-albumin ratio (CAR) constitute peripheral inflammatory indices. This study aimed to eva…
View article: Nrf2 Drives Epigenetic Reprogramming and Acts as the Master Regulator of KLF4 Expression and Activity in Arsenic‐Induced Transformation
Nrf2 Drives Epigenetic Reprogramming and Acts as the Master Regulator of KLF4 Expression and Activity in Arsenic‐Induced Transformation Open
Emerging evidence suggests that Nrf2 plays a pro‐carcinogenic role in multiple cancers. Previous studies have shown that arsenic‐induced Nrf2 activation drives metabolic reprogramming, leading to the formation of cancer stem‐like cells. He…
View article: Advances in the assessment and study of suicide in late-life depression
Advances in the assessment and study of suicide in late-life depression Open
With the aging global population, the prevalence of late-life depression (LLD) has shown a significant upward trend. The prolonged presence of a depressed mood can lead to feelings of hopelessness and helplessness, thereby enhancing suicid…
View article: Reframe Your Life Story: Interactive Narrative Therapist and Innovative Moment Assessment with Large Language Models
Reframe Your Life Story: Interactive Narrative Therapist and Innovative Moment Assessment with Large Language Models Open
Recent progress in large language models (LLMs) has opened new possibilities for mental health support, yet current approaches lack realism in simulating specialized psychotherapy and fail to capture therapeutic progression over time. Narr…
View article: Genome-wide mapping of arsenic-activated Nrf2 reveals metabolic and epigenetic reprogramming in induced pluripotent stem cells
Genome-wide mapping of arsenic-activated Nrf2 reveals metabolic and epigenetic reprogramming in induced pluripotent stem cells Open
View article: A cross sectional study of the diabetes mediated GGT to HDL ratio and cognitive function in older adults
A cross sectional study of the diabetes mediated GGT to HDL ratio and cognitive function in older adults Open
The rising incidence of cognitive disorders has become a significant challenge in global public health. The ratio of Gamma-glutamyl transferase (GGT) to high-density lipoprotein (HDL), associated with insulin resistance, has an unclear rel…
View article: Arsenic disrupts H3K9me3 and H3K27me3 balance by biasing PRC2.1 and PRC2.2 activity via PALI1 inhibition in carcinogenesis
Arsenic disrupts H3K9me3 and H3K27me3 balance by biasing PRC2.1 and PRC2.2 activity via PALI1 inhibition in carcinogenesis Open
Inorganic arsenic (As3+) is a well-established human carcinogen, yet the molecular mechanisms underlying its oncogenic potential remain incompletely understood. Here, we show that exposure to environmentally relevant concentrati…
View article: RAVENEA: A Benchmark for Multimodal Retrieval-Augmented Visual Culture Understanding
RAVENEA: A Benchmark for Multimodal Retrieval-Augmented Visual Culture Understanding Open
As vision-language models (VLMs) become increasingly integrated into daily life, the need for accurate visual culture understanding is becoming critical. Yet, these models frequently fall short in interpreting cultural nuances effectively.…
View article: The relationship between hepatic steatosis index and hypertension: NHANES 2011–2018
The relationship between hepatic steatosis index and hypertension: NHANES 2011–2018 Open
View article: Effects of the subanesthetic dose of esketamine on postoperative sleep quality in patients undergoing modified radical mastectomy: a randomized, double-blind controlled trial
Effects of the subanesthetic dose of esketamine on postoperative sleep quality in patients undergoing modified radical mastectomy: a randomized, double-blind controlled trial Open
Background Breast cancer is the most common malignant tumor among women worldwide. Surgical intervention is a critical component of treatment, yet the associated stress and anxiety can significantly disrupt postoperative sleep quality. Eme…
View article: Effectiveness and Safety of Memantine Add-on Treatment for Refractory Obsessive-Compulsive Disorder: A Meta-Analysis
Effectiveness and Safety of Memantine Add-on Treatment for Refractory Obsessive-Compulsive Disorder: A Meta-Analysis Open
Obsessive-compulsive disorder (OCD) is a highly disabling mental illness characterised by repetitive thoughts and behaviours that disrupt daily life and impair social functioning. The purpose of this meta-analysis was to assess the efficac…
View article: Media portrayals and social stigma surrounding COVID-19 survivors: a content analysis of Chinese media coverage
Media portrayals and social stigma surrounding COVID-19 survivors: a content analysis of Chinese media coverage Open
View article: Nrf2 and HIF1α converge to arsenic-induced metabolic reprogramming and the formation of the cancer stem-like cells: Erratum
Nrf2 and HIF1α converge to arsenic-induced metabolic reprogramming and the formation of the cancer stem-like cells: Erratum Open
[This corrects the article DOI: 10.7150/thno.42903.].
View article: Promoting *NO <sub>2</sub> Hydrogeneration on Cobalt‐Doped Copper Oxides for Selective Ammonia Electrosynthesis from Nitrate
Promoting *NO <sub>2</sub> Hydrogeneration on Cobalt‐Doped Copper Oxides for Selective Ammonia Electrosynthesis from Nitrate Open
Electrochemical nitrate reduction reaction (NO 3 RR) driven by renewable energy has attracted extensive attention, which can realize nitrate degradation and ammonia production simultaneously under ambient conditions. Copper−based catalysts…
View article: The Application of Genetic Algorithm in Seismic Performance Optimization of a Y-Eccentrically Braced Composite Frame
The Application of Genetic Algorithm in Seismic Performance Optimization of a Y-Eccentrically Braced Composite Frame Open
In this research, the seismic performance optimization of a Y-eccentrically braced composite frame (Y-EBCF) was conducted. An efficient fiber beam–spring element model, which considers the spatial composite effect of the RC slab, was propo…
View article: The Combination of a Novel Pleuromutilin Derivative and Polymyxin B Nonapeptide: An Example of Converting Pleuromutilin from Gram-Positive-Only to Broad-Spectrum
The Combination of a Novel Pleuromutilin Derivative and Polymyxin B Nonapeptide: An Example of Converting Pleuromutilin from Gram-Positive-Only to Broad-Spectrum Open
View article: Enhancing fluorescent probe design through multilayer interaction convolutional networks: advancing biosensing and bioimaging precision
Enhancing fluorescent probe design through multilayer interaction convolutional networks: advancing biosensing and bioimaging precision Open
Fluorescent probes are pivotal in biosensing and bioimaging, necessitating precise spectral tailoring for high-performance applications.
View article: Reframe Your Life Story: Interactive Narrative Therapist and Innovative Moment Assessment with Large Language Models
Reframe Your Life Story: Interactive Narrative Therapist and Innovative Moment Assessment with Large Language Models Open
View article: Spatially Selective Heterointerface Engineering Enables High-Efficiency Low-Frequency Microwave Absorption in Graphene/Tio 2 Composites
Spatially Selective Heterointerface Engineering Enables High-Efficiency Low-Frequency Microwave Absorption in Graphene/Tio 2 Composites Open
View article: Ginsenoside Rh2 Ameliorates Pulmonary Fibrosis Via Hsp70-P53-Dependent Autophagic Flux Regulation and Senescence Arrest
Ginsenoside Rh2 Ameliorates Pulmonary Fibrosis Via Hsp70-P53-Dependent Autophagic Flux Regulation and Senescence Arrest Open
View article: Lightweight Design of a New Type of Hinged Pentagonal Three Four Strut Open String Supported Dome Structure Based on the Quantum Beetle Whiskers Algorithm
Lightweight Design of a New Type of Hinged Pentagonal Three Four Strut Open String Supported Dome Structure Based on the Quantum Beetle Whiskers Algorithm Open
View article: Ginsenoside Rh2 Ameliorates Pulmonary Fibrosis Via Hsp70-Dependent Autophagic Flux Regulation and Senescence Arrest
Ginsenoside Rh2 Ameliorates Pulmonary Fibrosis Via Hsp70-Dependent Autophagic Flux Regulation and Senescence Arrest Open
View article: An Efficient and Generalizable Transfer Learning Method for Weather Condition Detection on Ground Terminals
An Efficient and Generalizable Transfer Learning Method for Weather Condition Detection on Ground Terminals Open
The increasing adoption of satellite Internet with low-Earth-orbit (LEO) satellites in mega-constellations allows ubiquitous connectivity to rural and remote areas. However, weather events have a significant impact on the performance and r…
View article: Elucidation of the key flavonol biosynthetic pathway in golden <i>Camellia</i> and its application in genetic modification of tomato fruit metabolism
Elucidation of the key flavonol biosynthetic pathway in golden <i>Camellia</i> and its application in genetic modification of tomato fruit metabolism Open
Golden Camellia refers to a group of species in the genus Camellia that display yellow petals. The secondary metabolites in these petals hold ornamental significance and potential health benefits. However, the biosynthetic mechanisms gover…