Yi Liu
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Introducing Medical Undergraduates to Germline <span>CNV</span> Analysis Using <span>LILRA3</span> : A Comparison Between Fluorescent <span>qPCR</span> and <span>PCR</span> ‐ <span>SSP</span> Techniques Open
In this study, fluorescent quantitative real‐time polymerase chain reaction (qPCR) and PCR‐sequence specific priming (PCR‐SSP) were introduced to medical undergraduates for germline copy number variation (CNV) analysis, using leukocyte imm…
Effect of OASL on oxaliplatin-induced immunogenic cell death in gastric cancer via the cGAS-STING signaling pathway Open
This study investigates the role of 2’-5’ oligoadenylate synthetase-like (OASL) in Oxaliplatin (OXA)-induced immunogenic cell death (ICD) in Gastric cancer (GC) cells through the cGAS-STING signaling pathway. Knockdown of OASL enhanced ICD…
Factors influencing acute pain after percutaneous vertebroplasty in patients with thoracolumbar fractures and its predictive model creation and validation Open
This study aims to analyze the risk factors for acute pain after percutaneous vertebroplasty in patients with thoracolumbar spine fracture and create a predictive model for validation. Clinical data of thoracolumbar spine fracture patients…
View article: Systemic immune-inflammation index: a key biomarker guiding personalized adjuvant chemotherapy in intrahepatic cholangiocarcinoma
Systemic immune-inflammation index: a key biomarker guiding personalized adjuvant chemotherapy in intrahepatic cholangiocarcinoma Open
Background Intrahepatic cholangiocarcinoma (ICC) is a highly aggressive primary liver malignancy, with poor long-term outcomes even after curative-intent resection. Postoperative adjuvant chemotherapy (pAC) is increasingly used, but its be…
Efficacy of distal perigastric lymphadenectomy for Siewert type II adenocarcinoma of the esophagogastric junction Open
Background To investigate the metastatic rates of distal perigastric lymph nodes (DPLN), including No.3b, 4d, 5, 6 and 12a LN stations, and to evaluate the clinical significance of DPLN lymphadenectomy for patients with Siewert type II ade…
Clostridioides difficile Bacteremia in an Elderly Female Patient After Colon Cancer Surgery Open
Clostridioides difficile infection (CDI) is a major healthcare-associated concern, particularly in the elderly. While CDI typically manifests as toxin-mediated colitis, hematogenous dissemination leading to bacteremia is relatively rare an…
Real-world treatment patterns and outcomes among patients with HER2-positive unresectable or metastatic breast cancer in China Open
Background Breast cancer is now the most commonly diagnosed cancer in the world and the leading cause of cancer mortality in women worldwide. In past few years, anti- human epidermal growth factor receptor-2 (HER2) therapy for metastatic b…
View article: Optogenetic activation of cortical microglia promotes neuronal activity and pain hypersensitivity
Optogenetic activation of cortical microglia promotes neuronal activity and pain hypersensitivity Open
Chronic pain following peripheral nerve injury is accompanied by increased neuronal activity in the somatosensory cortex. However, whether and how cortical microglia contribute to these changes is less understood. To this end, we applied a…
Is percutaneous endoscopic lumbar discectomy necessary for learning the unilateral biportal endoscopy technique? Open
Objective This study aims to investigate the effect of prior percutaneous endoscopic lumbar discectomy (PELD) surgical experience on the learning curve of the unilateral biportal endoscopy (UBE) technique. Methods A total of 200 patients u…
View article: SpaceR: Reinforcing MLLMs in Video Spatial Reasoning
SpaceR: Reinforcing MLLMs in Video Spatial Reasoning Open
Video spatial reasoning, which involves inferring the underlying spatial structure from observed video frames, poses a significant challenge for existing Multimodal Large Language Models (MLLMs). This limitation stems primarily from 1) the…
View article: Utility of 131I-HLX58-Der for the Precision Treatment: Evaluation of a Preclinical Radio-Antibody-Drug-Conjugate Approach in Mouse Models
Utility of 131I-HLX58-Der for the Precision Treatment: Evaluation of a Preclinical Radio-Antibody-Drug-Conjugate Approach in Mouse Models Open
These findings validate the potential of RADCs targeting CLDN18.2 in treating CLDN18.2-expressing solid tumors.
Functional Connectivity Alterations Associated with COVID-19-Related Sleep Problems: A Longitudinal Resting-State fMRI Study Open
This study provides insight into the changes in brain function associated with SP after COVID-19. These changes may partially explain the development of SP, and they also changed over time.
Visibility of mpMRI region of interest on ultrasound during cognitive fusion targeted biopsy predicts prostate cancer detection: a prospective single-center study Open
No. 2023-272-002, July 14, 2023.
View article: PunchBench: Benchmarking MLLMs in Multimodal Punchline Comprehension
PunchBench: Benchmarking MLLMs in Multimodal Punchline Comprehension Open
Multimodal punchlines, which involve humor or sarcasm conveyed in image-caption pairs, are a popular way of communication on online multimedia platforms. With the rapid development of multimodal large language models (MLLMs), it is essenti…
Effect of soft and hard segments ratio of waterborne polyurethane on the properties of modified basalt fiber reinforced polypropylene composites Open
The interaction between fiber and polymer matrix is crucial for the properties of fiber‐reinforced composites. This paper explored the use of end‐capped waterborne polyurethanes (WPU) modified basalt fiber (BF) to reinforce the polypropyle…