Xuanjun Wang
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View article: Substitution of 25% of chemical fertilizer nitrogen with organic amendments nitrogen reduces N2O emissions from tea plantation soils in subtropical China
Substitution of 25% of chemical fertilizer nitrogen with organic amendments nitrogen reduces N2O emissions from tea plantation soils in subtropical China Open
Tea plantation soils are recognized hotspots for nitrous oxide (N 2 O) emissions due to excessive amounts of nitrogen fertilizer applied, yet the potential of partially substituting chemical fertilizers with organic amendments to mitigate …
View article: Selenium‐Polysaccharides: Structural Characterization, Biological Activities, and Emerging Applications
Selenium‐Polysaccharides: Structural Characterization, Biological Activities, and Emerging Applications Open
Selenium‐polysaccharides (SePs) are an emerging class of bioactive compounds formed by incorporating inorganic Se into polysaccharides, exhibiting enhanced biological activity compared to inorganic Se or isolated polysaccharides. The extra…
View article: Tuning Anion Chemistry to Enhance Bulk and Interfacial Stability in Low‐Temperature Lithium Metal Batteries
Tuning Anion Chemistry to Enhance Bulk and Interfacial Stability in Low‐Temperature Lithium Metal Batteries Open
The stable operation of lithium metal batteries in cold climates is significantly constrained by insufficient dynamics within both the bulk and interfacial regions of the electrolyte. In the study, an in‐situ polymerized quasi‐solid‐state …
View article: Polymeric Desensitizer Fluororubber: A Good Binder to Improve the Thermal Stability and Mechanical Properties of 3,4-Dinitrofurazanfuroxan
Polymeric Desensitizer Fluororubber: A Good Binder to Improve the Thermal Stability and Mechanical Properties of 3,4-Dinitrofurazanfuroxan Open
3,4-Dinitrofurazanfuroxan (DNTF) is characterized by its high energy, high detonation velocity, strong explosive power, and small critical diameter for detonation. However, its practical application is limited by poor thermal stability and…
View article: Controllable Preparation and Thermochemical Properties of Ultrafine FOX-7 by Microfluidic Crystallization Strategy
Controllable Preparation and Thermochemical Properties of Ultrafine FOX-7 by Microfluidic Crystallization Strategy Open
The 1,1-diamino-2,2-dinitroethylene (FOX-7) has been adopted in high-energy explosives. To further improve the thermal safety and detonation performance of FOX-7, a microfluidic crystallization platform with a swirl-shaped chip was employe…
View article: Stephanine interacts with TNF-α to block NF-κB signaling and protects against rheumatoid arthritis
Stephanine interacts with TNF-α to block NF-κB signaling and protects against rheumatoid arthritis Open
Tumor necrosis factor-α (TNF-α) is a key player in the pathogenesis of rheumatoid arthritis (RA) and considered a promising target for therapeutic drug development. Activation of the nuclear factor-kappa B (NF-κB) pathway upon TNF-α bindin…
View article: Evaluating the Components, Nutrients, and Antioxidant and Anti-Inflammatory Properties of Centranthera grandiflora Benth Extracts
Evaluating the Components, Nutrients, and Antioxidant and Anti-Inflammatory Properties of Centranthera grandiflora Benth Extracts Open
Background: Centranthera grandiflora Benth is commonly utilized in China to take advantage of its purported health benefits. Methods: Here, the chemical composition, nutritional value, and bioactivity of C. grandiflora Benth extract (CGE) …
View article: EGCG prevents bone loss in ovariectomized mice by suppressing osteoclastogenesis via the inhibition of NF-κB, MAPK, and AKT signaling pathways
EGCG prevents bone loss in ovariectomized mice by suppressing osteoclastogenesis via the inhibition of NF-κB, MAPK, and AKT signaling pathways Open
Excessive osteoclastogenesis-mediated osteoporosis has been recognized as a global health concern. Candidate compounds derived from medicinal plants or functional foods are promising to treat osteoporosis due to their high safety and effic…
View article: Selenium and Selenoproteins: Mechanisms, Health Functions, and Emerging Applications
Selenium and Selenoproteins: Mechanisms, Health Functions, and Emerging Applications Open
Selenium (Se) is an essential trace element crucial for human health that primarily functions as an immunonutrient. It is incorporated into polypeptides such as selenocysteine (SeC) and selenomethionine (SeMet), two key amino acids involve…
View article: Recent Advances and Perspectives on Coupled Water Electrolysis for Energy‐Saving Hydrogen Production
Recent Advances and Perspectives on Coupled Water Electrolysis for Energy‐Saving Hydrogen Production Open
Overall water splitting (OWS) to produce hydrogen has attracted large attention in recent years due to its ecological‐friendliness and sustainability. However, the efficiency of OWS has been forced by the sluggish kinetics of the four‐elec…
View article: Research Advances on Lithium‐Ion Batteries Calendar Life Prognostic Models
Research Advances on Lithium‐Ion Batteries Calendar Life Prognostic Models Open
In military reserve power supplies, there is an urgent need for superior secondary batteries to replace conventional primary batteries, and lithium‐ion batteries (LIBs) emerge as one of the best choices due to their exceptional performance…
View article: Axillaridine A suppresses osteoclastogenesis and alleviates ovariectomy-induced bone loss <i>via</i> inhibition of RANKL-mediated RANK signaling pathways
Axillaridine A suppresses osteoclastogenesis and alleviates ovariectomy-induced bone loss <i>via</i> inhibition of RANKL-mediated RANK signaling pathways Open
Steroidal alkaloids are the main active components in many medicinal plants and exhibit diverse biological activities. Axillaridine A (AA) is a newly discovered steroidal alkaloid. However, whether AA could suppress osteoclastogenesis and …
View article: Stephanine Protects Against Osteoporosis by Suppressing Osteoclastogenesis via Inhibition of the <scp>RANKL</scp>—<scp>RANK</scp> Interaction
Stephanine Protects Against Osteoporosis by Suppressing Osteoclastogenesis via Inhibition of the <span>RANKL</span>—<span>RANK</span> Interaction Open
The interaction between the receptor activator of nuclear factor‐κB ligand (RANKL) and its receptor RANK is known to regulate osteoclastogenesis in bone remodelling and has become an important therapeutic target for the treatment of osteop…
View article: RETRACTED: An experimental study on the erosion of solid propellant by cavitation water jet in submerged environment
RETRACTED: An experimental study on the erosion of solid propellant by cavitation water jet in submerged environment Open
The submerged cavitation water jet (SCWJ) is a promising technology for removing solid propellant from old solid rocket engines and recycling them. In this study, the feasibility of using SCWJ to break solid propellant is investigated. The…
View article: Inhibitory effect of 1,4,5,6-tetrahydroxy-7,8-diprenylxanthone against NSCLC with L858R/T790M/C797S mutant EGFR
Inhibitory effect of 1,4,5,6-tetrahydroxy-7,8-diprenylxanthone against NSCLC with L858R/T790M/C797S mutant EGFR Open
Epidermal growth factor receptor (EGFR)-activating mutations are critical factors in the development of EGFR-driven non-small-cell lung cancer (NSCLC), and molecular targeted therapies have focused on inhibiting these mutations. EGFR tyros…
View article: Effect of heat treatment on microstructure and hydrogen embrittlement of additively manufactured and cast 18Ni300 maraging steel
Effect of heat treatment on microstructure and hydrogen embrittlement of additively manufactured and cast 18Ni300 maraging steel Open
The microstructure is significantly different between cast and additively manufactured 18Ni300 maraging steel due to the different manufacturing principles. The resulting differences in hydrogen embrittlement susceptibility need to be clar…
View article: Dihydrotanshinone I promotes LDL uptake by HepG2 cells through increasing LDLR level
Dihydrotanshinone I promotes LDL uptake by HepG2 cells through increasing LDLR level Open
Dihydrotanshinone I (DHT), a lipophilic compound extracted from Salvia miltiorrhiza, has cardiovascular protective effects, but the underlying molecular mechanisms of action have rarely been reported. Based on this, whether DHT affects cho…
View article: Quantitative evaluation on the cavitation damage energy of metals via multiscale approaches
Quantitative evaluation on the cavitation damage energy of metals via multiscale approaches Open
In-situ experimental observation cannot be an effective method in the impact process of metal cavitation erosion, and the impact damage energy prediction theory has not been established based on a detailed mathematical and physical model. …
View article: Chlorogenic acid alleviates renal fibrosis by reducing lipid accumulation in diabetic kidney disease through suppressing the Notch1 and Stat3 signaling pathway
Chlorogenic acid alleviates renal fibrosis by reducing lipid accumulation in diabetic kidney disease through suppressing the Notch1 and Stat3 signaling pathway Open
CA reduces renal lipid accumulation and improves DKD renal fibrosis by inhibiting Notch1 and stat3 signaling pathways.
View article: Oleanolic acid inhibits cholesterol synthesis by suppressing the expression and enzymatic activity of HMGCR
Oleanolic acid inhibits cholesterol synthesis by suppressing the expression and enzymatic activity of HMGCR Open
This study investigated the impact of Oleanolic Acid (OA) on cholesterol metabolism and. MTT assays demonstrated that OA had no cytotoxic effects on HepG2 cells at concentrations below 20 μM. Subsequent experiments focused on 3-hydroxy-3-m…
View article: Gallic Acid Can Promote Low-Density Lipoprotein Uptake in HepG2 Cells via Increasing Low-Density Lipoprotein Receptor Accumulation
Gallic Acid Can Promote Low-Density Lipoprotein Uptake in HepG2 Cells via Increasing Low-Density Lipoprotein Receptor Accumulation Open
Gallic acid (GA) is a type of polyphenolic compound that can be found in a range of fruits, vegetables, and tea. Although it has been confirmed it improves non-alcoholic fatty liver disease (NAFLD), it is still unknown whether GA can impro…
View article: 20(S)-Protopanaxatriol Improves Atherosclerosis by Inhibiting Low-Density Lipoprotein Receptor Degradation in ApoE KO Mice
20(S)-Protopanaxatriol Improves Atherosclerosis by Inhibiting Low-Density Lipoprotein Receptor Degradation in ApoE KO Mice Open
Atherosclerosis (AS) is a chronic progressive disease caused by various factors and causes various cerebrovascular and cardiovascular diseases (CVDs). Reducing the plasma levels of low-density lipoprotein cholesterol is the primary goal in…
View article: Colitis can be Improved by (−)-Epigallocatechin Gallate through Targeting Notch in DSS-induced UC mice
Colitis can be Improved by (−)-Epigallocatechin Gallate through Targeting Notch in DSS-induced UC mice Open
Background: Ulcerative colitis (UC) is a chronic and non-specific inflammatory bowel disease. Previous research shows that Notch plays a role in the pathogenesis of UC and (−)-Epigallocatechin Gallate(EGCG) could attenuate colitis. However…
View article: HPLC and LC–MS/MS-Based Quantitative Characterization of Related Substances Associated with Sotalol Hydrochloride
HPLC and LC–MS/MS-Based Quantitative Characterization of Related Substances Associated with Sotalol Hydrochloride Open
In total, three related substances (RS) associated with sotalol hydrochloride (STHCl) were herein identified with a novel gradient high-performance liquid chromatography (HPLC) protocol. Further characterization of these substances was the…