Xiaojing Li
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View article: A ratio-based framework using Quartet reference materials for integrating long- and short-read RNA-seq
A ratio-based framework using Quartet reference materials for integrating long- and short-read RNA-seq Open
Long-read RNA sequencing (lrRNA-seq) enables full-length transcript profiling but is confounded by technical batch effects that compromise quantification and prevent data integration across platforms, protocols, and laboratories. The lack …
View article: Liupao tea attenuates ulcerative colitis through modulation of inflammation and intestinal barrier function
Liupao tea attenuates ulcerative colitis through modulation of inflammation and intestinal barrier function Open
View article: Defensin proteins AtPDF1.2A and AtPDF1.2C mediate cadmium accumulation and plant growth in Arabidopsis
Defensin proteins AtPDF1.2A and AtPDF1.2C mediate cadmium accumulation and plant growth in Arabidopsis Open
Cadmium is transported in xylem sap as Cd2+ or Cd-protein chelates, which regulates shoot Cd accumulation; however, the proteins involved in this process have remained unknown in Arabidopsis. Here, we identified eight Cd-inducib…
View article: Exploring the molecular mechanism of EGCG in preventing obesity-induced precocious puberty based on serum metabolomics and molecular docking
Exploring the molecular mechanism of EGCG in preventing obesity-induced precocious puberty based on serum metabolomics and molecular docking Open
Objective Obesity-induced precocious puberty presents serious health risks to adolescents. Building on our previous finding that epigallocatechin gallate (EGCG) exhibits a preventive effect on obesity-induced precocious puberty, the presen…
View article: TSHR‐Targeting Nucleic Acid Aptamer Treats Graves' Ophthalmopathy via Novel Allosteric Inhibition
TSHR‐Targeting Nucleic Acid Aptamer Treats Graves' Ophthalmopathy via Novel Allosteric Inhibition Open
Graves' ophthalmopathy (GO) is an autoimmune disorder marked by orbital inflammation and tissue remodeling, leading to irreversible disfigurement and vision loss. The current first‐line glucocorticoid therapy remains palliative, underscori…
View article: Determination of trace polychlorinated biphenyls in environmental water samples by solid-phase microextraction-gas chromatography-tandem mass spectrometry using carbon nanotube composite microspheres materials
Determination of trace polychlorinated biphenyls in environmental water samples by solid-phase microextraction-gas chromatography-tandem mass spectrometry using carbon nanotube composite microspheres materials Open
Polychlorinated biphenyls （PCBs） pose serious threats to the environment and human health because they are among the most common and persistent organic pollutants globally. In this study， six PCBs were extracted from environmental water sa…
View article: A ratio-based framework using Quartet reference materials for integrating long- and short-read RNA-seq
A ratio-based framework using Quartet reference materials for integrating long- and short-read RNA-seq Open
Long-read RNA sequencing (lrRNA-seq) enables full-length transcript profiling but is confounded by technical batch effects that compromise quantification and prevent data integration across platforms, protocols, and laboratories. The lack …
View article: Role of eIF4E in mediating cytotoxic effect of HHT and ATO on AML cells in bone marrow microenvironment
Role of eIF4E in mediating cytotoxic effect of HHT and ATO on AML cells in bone marrow microenvironment Open
eIF4E may play an essential role in mediating the cytotoxic effects of HHT and ATO, representing a novel therapeutic target in AML.
View article: A novel combination therapy with Uridine and Praziquantel effectively alleviates schistosomiasis-induced hepatic fibrosis through promoting adipogenic differentiation
A novel combination therapy with Uridine and Praziquantel effectively alleviates schistosomiasis-induced hepatic fibrosis through promoting adipogenic differentiation Open
Schistosomiasis-induced hepatic fibrosis, a consequence of egg-induced granulomatous lesions, remains untreated by current drugs. Therefore, the development of novel antifibrosis drugs is of paramount importance. Our previous study indicat…
View article: Comparative transcriptome analysis reveal gene regulation of dormancy release in Cardiocrinum giganteum seeds induced by temperature
Comparative transcriptome analysis reveal gene regulation of dormancy release in Cardiocrinum giganteum seeds induced by temperature Open
The Cardiocrinum giganteum is a bulbous plant with extremely high ornamental and economic values. The study revealed that seeds require an extended period of variable temperature stratification treatment to overcome dormancy and initiate g…
View article: Innovative yarn modeling with fiber damage for predicting friction and wear in textile reinforcement manufacturing
Innovative yarn modeling with fiber damage for predicting friction and wear in textile reinforcement manufacturing Open
View article: Association Between Lifestyle Modifications and Renal Function Decline in Elderly Diabetic Nephropathic Patients: a Meta-Analysis Approach
Association Between Lifestyle Modifications and Renal Function Decline in Elderly Diabetic Nephropathic Patients: a Meta-Analysis Approach Open
View article: The impact of perceived teacher support on students’ learning approach: the chain mediating role of academic engagement and achievement goal orientation
The impact of perceived teacher support on students’ learning approach: the chain mediating role of academic engagement and achievement goal orientation Open
Introduction This present study investigated the influential effects of university students’ perceived teacher support on their learning approach by drawing on Personal Investment Theory and selecting academic engagement, mastery-avoidance…
View article: Population pharmacokinetics of colistin sulfate in critically ill patients based on NONMEM
Population pharmacokinetics of colistin sulfate in critically ill patients based on NONMEM Open
View article: AutoRAC: Automated Processing-in-Memory Accelerator Design for Recommender Systems
AutoRAC: Automated Processing-in-Memory Accelerator Design for Recommender Systems Open
The performance bottleneck of deep-learning-based recommender systems resides in their backbone Deep Neural Networks. By integrating Processing-In-Memory~(PIM) architectures, researchers can reduce data movement and enhance energy efficien…
View article: Patterns and drivers of water-land resources nexus in arid inland river basins of northwestern China
Patterns and drivers of water-land resources nexus in arid inland river basins of northwestern China Open
The underlying land surface structure is being reshaped by climate change and human activities, which in turn affects the hydrological processes. However, the patterns and drivers of water and land resources nexus (WLN) in arid inland rive…
View article: Customized CAD/CAM coral hydroxyapatite block for horizontal ridge augmentation in severe bone defects: A case report
Customized CAD/CAM coral hydroxyapatite block for horizontal ridge augmentation in severe bone defects: A case report Open
Limited data are available on the application of customized bone blocks for horizontal ridge augmentation, particularly those fabricated using coral hydroxyapatite (CHA). The present case report describes a technique for bone augmentation …
View article: Role of autophagy in rejection after solid organ transplantation: A systematic review of the literature
Role of autophagy in rejection after solid organ transplantation: A systematic review of the literature Open
Organ transplantation has long been recognized as an effective treatment for end-stage organ failure, metabolic diseases, and malignant tumors. However, graft rejection caused by major histocompatibility complex mismatch remains a signific…
View article: Preparation of Light‐Colored Botanical Sunscreen from Pink Birch Lignin
Preparation of Light‐Colored Botanical Sunscreen from Pink Birch Lignin Open
Lignin holds significant potential in UV‐blocking and skincare products. However, its application has been hindered by the dark color. Herein, a pink lignin (PL) is successfully extracted from birch under mild condition, with molecular wei…
View article: Synchrony of gross primary productivity resistance and resilience in rapid response to spring excessive precipitation across northern China’s dryland ecosystems
Synchrony of gross primary productivity resistance and resilience in rapid response to spring excessive precipitation across northern China’s dryland ecosystems Open
Spring precipitation directly impacts the growth and development of vegetation in dryland ecosystems, which in turn affects the biomass of the growing season and fundamentally maintains the ecosystem stability. However, the effects of rece…
View article: Effects of Management Practices on Soil Microbial Diversity and Structure on Eucalyptus Plantations
Effects of Management Practices on Soil Microbial Diversity and Structure on Eucalyptus Plantations Open
Soil microbes are critical in regulating the growth and function of eucalyptus plantations. The mechanisms underlying soil microbial communities’ response to different eucalyptus plantation management practices remain elusive. In this stud…
View article: TSHR-targeting nucleic acid aptamer treats Graves’ ophthalmopathy via novel allosteric inhibition
TSHR-targeting nucleic acid aptamer treats Graves’ ophthalmopathy via novel allosteric inhibition Open
Abnormal thyrotropin receptor (TSHR) signaling drives a spectrum of diseases affecting hundreds of millions globally, including Graves’ disease (GD), Graves’ ophthalmopathy (GO), hyperthyroidism, and thyroid cancers. Therefore, TSHR is con…
View article: Tissue-resident peripheral helper T cells foster hepatocellular carcinoma immune evasion by promoting regulatory B-cell expansion
Tissue-resident peripheral helper T cells foster hepatocellular carcinoma immune evasion by promoting regulatory B-cell expansion Open
Background: Peripheral helper T (T PH ) cells are uniquely positioned within pathologically inflamed non-lymphoid tissues to stimulate B-cell responses and antibody production. However, the phenotype, function, and clinical relevance of T …
View article: Structural flexible magnetic films for biometric encryption and tactile interaction in wearable devices
Structural flexible magnetic films for biometric encryption and tactile interaction in wearable devices Open
Human fingers have fingerprints and mechanoreceptors for biometric information encryption and tactile perception. Ideally, electronic skin (e-skin) integrates identity information and tactile sensing, but this remains challenging. Research…
View article: Mass spectrometry imaging reveals spatial metabolic variation and the crucial role of uridine metabolism in liver injury caused by Schistosoma japonicum
Mass spectrometry imaging reveals spatial metabolic variation and the crucial role of uridine metabolism in liver injury caused by Schistosoma japonicum Open
Schistosomiasis is the second most important parasitic disease worldwide. Schistosomiasis japonica is a unique species endemic to southern China, and schistosomiasis is characterized by severe liver injury, inflammation, liver granuloma, a…
View article: A quantitative model of indoor illuminance and light color combinations effects on different initial emotional states using physiological measures
A quantitative model of indoor illuminance and light color combinations effects on different initial emotional states using physiological measures Open
View article: Isolation, Purification, Structural Characterization, and Antitumor Activity of Novel Compounds from Tiebangchui
Isolation, Purification, Structural Characterization, and Antitumor Activity of Novel Compounds from Tiebangchui Open
View article: Aging Mechanism of Lithium-Ion Batteries after Thermal Management Based on Alternating Current Self-Heating at Low Temperature
Aging Mechanism of Lithium-Ion Batteries after Thermal Management Based on Alternating Current Self-Heating at Low Temperature Open
View article: Can Regulatory Sandbox Boost Bank Profitability?
Can Regulatory Sandbox Boost Bank Profitability? Open
View article: The Preparation and Synthesis Mechanism of Tin Nanoparticles by Emulsion Detonation Method
The Preparation and Synthesis Mechanism of Tin Nanoparticles by Emulsion Detonation Method Open