Xuede Zhang
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View article: Real‑world evidence of advanced non‑small cell lung carcinoma treated with an immune checkpoint inhibitor plus chemotherapy
Real‑world evidence of advanced non‑small cell lung carcinoma treated with an immune checkpoint inhibitor plus chemotherapy Open
Immunotherapy is an effective treatment strategy for patients with advanced non-small cell lung cancer (NSCLC). Although clinical trials on immunotherapy have provided promising results, real-world research in clinical practice is needed t…
View article: Exosomal miRNA-profiling of pleural effusion in lung adenocarcinoma and tuberculosis
Exosomal miRNA-profiling of pleural effusion in lung adenocarcinoma and tuberculosis Open
Background Pleural effusion (PE) caused by lung cancer is prevalent, and it is difficult to differentiate it from PE caused by tuberculosis. Exosome-based liquid biopsy offers a non-invasive technique to diagnose benign and malignant PE. E…
View article: Expression Status and Prognostic Values of SOCS Family Genes in Non-small Cell Lung Cancer
Expression Status and Prognostic Values of SOCS Family Genes in Non-small Cell Lung Cancer Open
Backgroud: Suppressors of cytokine signaling (SOCS) family play important roles in the development of cancers by inhibiting the transmission of the Janus kinases–signal transducers and activators of transcription (JAK-STAT) signaling pathw…
View article: Expression status and prognostic value of the perilipin family of genes in breast cancer.
Expression status and prognostic value of the perilipin family of genes in breast cancer. Open
The findings from this study indicated that genes in the PLIN family were aberrantly expressed in breast cancer and may serve as novel therapeutic targets as well as prognostic biomarkers for the disease.
View article: PANX1 is a potential prognostic biomarker associated with immune infiltration in pancreatic adenocarcinoma: A pan-cancer analysis
PANX1 is a potential prognostic biomarker associated with immune infiltration in pancreatic adenocarcinoma: A pan-cancer analysis Open
Pannexin 1 (PANX1) channel is a critical ATP-releasing pathway that modulates tumor immunity, progression, and prognosis. However, the roles of PANX1 in different cancers remain unclear. We analyzed the expression of PANX1 in human pan-can…
View article: Quantitative proteomics analysis of mitochondrial proteins in lung adenocarcinomas and normal lung tissue using iTRAQ and tandem mass spectrometry.
Quantitative proteomics analysis of mitochondrial proteins in lung adenocarcinomas and normal lung tissue using iTRAQ and tandem mass spectrometry. Open
Lung adenocarcinoma is the most common type of lung cancer. Unfortunately, lung adenocarcinoma has a poor prognosis and the pathogenesis remains unclear. Mitochondria are important mediators of tumorigenesis. However, the proteomics profil…