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View article: Polystyrene microspheres could inhibit the ferroptosis of prostate cancer cells via USP39/IGF2BP3/MAPK4 axis
Polystyrene microspheres could inhibit the ferroptosis of prostate cancer cells via USP39/IGF2BP3/MAPK4 axis Open
These findings illuminate the complex relationship between environmental pollutants such as PS and cancer progression, offering new avenues for research and potential therapeutic interventions in prostate cancer.
View article: Accuracy comparison of intraocular lens power calculation formulas in Post-LASIK myopic eyes
Accuracy comparison of intraocular lens power calculation formulas in Post-LASIK myopic eyes Open
View article: Enhancing Diagnostic Precision: Utilising a Large Language Model to Extract U Scores from Thyroid Sonography Reports
Enhancing Diagnostic Precision: Utilising a Large Language Model to Extract U Scores from Thyroid Sonography Reports Open
This study evaluates the performance of ChatGPT-4, a Large Language Model (LLM), in automatically extracting U scores from free-text thyroid ultrasound reports collected from University Hospitals Birmingham (UHB), UK, between 2014 and 2024…
View article: A Novel and Secure 3D Colour Medical Image Encryption Technique Using 3D Hyperchaotic Map, S-box and Discrete Wavelet Transform
A Novel and Secure 3D Colour Medical Image Encryption Technique Using 3D Hyperchaotic Map, S-box and Discrete Wavelet Transform Open
Over the past two decades, there has been a substantial increase in the use of the Internet of Medical Things (IoMT). In the smart healthcare setting, patients’ data can be quickly collected, stored and processed through insecure medium su…
View article: Recent Advances in Generative Models for Synthetic Brain MRI Image Generation
Recent Advances in Generative Models for Synthetic Brain MRI Image Generation Open
With the use of artificial intelligence (AI) for image analysis of Magnetic Resonance Imaging (MRI), the lack of training data has become an issue. Realistic synthetic MRI images can serve as a solution and generative models have been prop…
View article: Analysing the Association Between User Perceptions and Usage Patterns of Digital Personalised Care Platforms Using the UTAUT Framework: Insights from the ADLIFE Project
Analysing the Association Between User Perceptions and Usage Patterns of Digital Personalised Care Platforms Using the UTAUT Framework: Insights from the ADLIFE Project Open
This study explores the relationship between user perceptions, as measured by the extended Unified Theory of Acceptance and Use of Technology (UTAUT) model, and actual usage patterns of the ADLIFE Digital Personalized Care Platform. Data w…
View article: A unified eIF1A<sup>+</sup>luminal cells-centered hypoxic and “cold” tumor microenvironment promotes PCa progression among different subtypes
A unified eIF1A<sup>+</sup>luminal cells-centered hypoxic and “cold” tumor microenvironment promotes PCa progression among different subtypes Open
PCa is a malignancy with high heterogeneity arises from both tumor microenvironment (TME) and histological subtypes. To achieve superior clinical efficacy, it is imperative to identify unified progression drivers within such heterogeneity …
View article: MDK promotes M2 macrophage polarization to remodel the tumour microenvironment in clear cell renal cell carcinoma
MDK promotes M2 macrophage polarization to remodel the tumour microenvironment in clear cell renal cell carcinoma Open
The efficacy of immunotherapy for clear cell renal cell carcinoma (ccRCC), especially advanced ccRCC, is limited, presenting a clinical challenge. This limitation is closely tied to the immune regulation network. Understanding the heteroge…
View article: Effect of transdermal drug delivery patches on the stratum corneum: in vivo inspection with a handheld terahertz probe: publisher’s note
Effect of transdermal drug delivery patches on the stratum corneum: in vivo inspection with a handheld terahertz probe: publisher’s note Open
This publisher’s note contains a correction to Biomed. Opt. Express 15 , 3064 ( 2024 ). 10.1364/BOE.513557
View article: Variation of skin hydration profile with biophysical factors and lifestyle revealed by in vivo terahertz sensing
Variation of skin hydration profile with biophysical factors and lifestyle revealed by in vivo terahertz sensing Open
The skin, being the body’s largest organ, plays a pivotal role in protecting the body against dangerous external factors. The maintenance of adequate hydration levels is essential for the skin to fulfill this protective function. However, …
View article: Manual reduction in testicular torsion and subsequent treatment after successful reduction: a series of reports in a single institution
Manual reduction in testicular torsion and subsequent treatment after successful reduction: a series of reports in a single institution Open
Introduction To explore the factors affecting the success of testicular torsion manual reduction and the safety of subsequent conservative treatment after successful reduction. Methods Clinical data of 66 patients with testicular torsion t…
View article: Effect of transdermal drug delivery patches on the stratum corneum: in vivo inspection with a handheld terahertz probe
Effect of transdermal drug delivery patches on the stratum corneum: in vivo inspection with a handheld terahertz probe Open
Transdermal drug delivery patches are a good alternative to hypodermic drug injection. The drug delivery efficiency depends strongly on the hydration of the skin under treatment, and therefore, it is essential to study the effects on the s…
View article: Terahertz probe for real time in vivo skin hydration evaluation
Terahertz probe for real time in vivo skin hydration evaluation Open
This study introduces a handheld terahertz (THz) scanner designed to quantitatively evaluate human skin hydration levels and thickness. This device, through the incorporation of force sensors, demonstrates enhanced repeatability and accura…
View article: Associations between the gut microbiota and prostatitis: visions from a two-sample Mendelian randomization analysis
Associations between the gut microbiota and prostatitis: visions from a two-sample Mendelian randomization analysis Open
Background A growing body of research indicates a substantial correlation between the gut microbiota and prostatitis. However, there is still a lack of relevant evidence at the big data level. Two-sample Mendelian randomization was employe…
View article: A Comparison of Modern Cardiovascular Parameters in Patients with and Without Blood Stasis Syndrome
A Comparison of Modern Cardiovascular Parameters in Patients with and Without Blood Stasis Syndrome Open
Objective: To study the relation between cardiovascular parameters and blood stasis syndrome (BSS) by investigating the conventional cardiovascular parameters of BSS, furthermore, finding out the objective evidence for TCM syndrome differe…
View article: Spectroscopic insight on impact of environment on natural photoprotectants
Spectroscopic insight on impact of environment on natural photoprotectants Open
Biomimicry has become a key player in researching new materials for a whole range of applications.
View article: The effect of transdermal drug delivery patches on stratum corneum: in vivo inspection with a handheld terahertz system
The effect of transdermal drug delivery patches on stratum corneum: in vivo inspection with a handheld terahertz system Open
This is the data shown in the paper entitled: The effect of transdermal drug delivery patches on stratum corneum: in vivo inspection with a handheld terahertz system
View article: Quantitative evaluation of transdermal drug delivery patches on human skin with in vivo THz-TDS
Quantitative evaluation of transdermal drug delivery patches on human skin with in vivo THz-TDS Open
Transdermal drug delivery (TDD) has been widely used in medical treatments due to various advantages, including delivering drugs at a consistent rate. However, variations in skin hydration can have a significant effect on the permeability …
View article: Application of single-point prostate biopsy in elderly patients with highly suspected prostate cancer
Application of single-point prostate biopsy in elderly patients with highly suspected prostate cancer Open
Objective To explore the feasibility of single-point prostate biopsy in elderly patients with highly suspected prostate cancer. Methods Forty-three patients with a prostate imaging reporting and data system score (PI-RADS) of 5, age ≥ 80 y…
View article: Comparison of the Oncological and Functional Outcomes of Brachytherapy and Radical Prostatectomy for Localized Prostate Cancer
Comparison of the Oncological and Functional Outcomes of Brachytherapy and Radical Prostatectomy for Localized Prostate Cancer Open
Background and Objectives: To compare the oncological and functional outcomes of brachytherapy (BT) and radical prostatectomy (RP) in patients with localized prostate cancer (PCa). Materials and Methods: We retrospectively analyzed data fr…
View article: The Application of Biopsy Density in Transperineal Templated-Guided Biopsy Patients With PI-RADS<3
The Application of Biopsy Density in Transperineal Templated-Guided Biopsy Patients With PI-RADS<3 Open
Background In patients with multiparameter magnetic resonance imaging (mpMRI) low-possibility but highly clinical suspicion of prostate cancer, the biopsy core is unclear. Our study aims to introduce the biopsy density (BD; the ratio of bi…
View article: Efficacy of Dexamethasone intravitreal implant in treating non-arteritic anterior ischemic optic neuropathy
Efficacy of Dexamethasone intravitreal implant in treating non-arteritic anterior ischemic optic neuropathy Open
AIM: To explore the therapeutic effects and safety of dexamethasone intravitreal implant(DEX)on non-arteritic anterior ischemic optic neuropathy(NAION), and responses to the different course of disease.METHODS: Totally 70 patients(70 eyes)…
View article: Optimized multilayer structure for sensitive THz characterization of thin-film glucose solutions
Optimized multilayer structure for sensitive THz characterization of thin-film glucose solutions Open
Terahertz time-domain spectroscopy (THz-TDS) has shown promise in biomedical sample characterization and high characterization sensitivity is in demand due to the thin-film (TF) feature of the sample. This paper proposes an optimized multi…
View article: The application of intraoperative frozen section examination in multiparametric magnetic resonance imaging/transrectal ultrasound fusion prostate biopsy during a major pandemic
The application of intraoperative frozen section examination in multiparametric magnetic resonance imaging/transrectal ultrasound fusion prostate biopsy during a major pandemic Open
BACKGROUND: To investigate the value of intraoperative frozen section examination (IFSE) in multiparametric magnetic resonance imaging/transrectal ultrasound (mpMRI/TRUS) fusion prostate biopsy in a major pandemic. METHODS: A total of 35 p…
View article: Pelvic plexus block to provide better anesthesia in transperineal template-guided prostate biopsy: a randomised controlled trial
Pelvic plexus block to provide better anesthesia in transperineal template-guided prostate biopsy: a randomised controlled trial Open
View article: Marital status independently predicts prostate cancer survival in men who underwent radical prostatectomy: An analysis of 95,846 individuals
Marital status independently predicts prostate cancer survival in men who underwent radical prostatectomy: An analysis of 95,846 individuals Open
Marital status is an independent prognostic factor for survival in several types of cancer, but has not been fully studied in prostate cancer (PCa). A total of 95,846 men diagnosed with PCa were treated with radical prostatectomy (RP) betw…
View article: Identification of TMPRSS2-ERG mechanisms in prostate cancer invasiveness: Involvement of MMP-9 and plexin B1
Identification of TMPRSS2-ERG mechanisms in prostate cancer invasiveness: Involvement of MMP-9 and plexin B1 Open
The relationship of TMPRSS2-ERG fusion gene with matrix metalloproteinase-9 (MMP-9) and PLXNB1 (plexin B1) in regulation of prostate cancer (PCa) aggressiveness was investigated. Fluorescence in situ hybridization (FISH) assays, qRT-PCR an…
View article: Predictive value of neutrophil-to-lymphocyte ratio in diagnosis of prostate cancer among men who underwent template-guided prostate biopsy
Predictive value of neutrophil-to-lymphocyte ratio in diagnosis of prostate cancer among men who underwent template-guided prostate biopsy Open
To evaluate the predictive value of neutrophil-to-lymphocyte ratio (NLR) in diagnosis of prostate cancer (PCa). Data of 662 patients who underwent prostate biopsy from January 2012 to June 2016 were retrospectively reviewed. The receiver o…
View article: Effect of prostate volume on the peripheral nerve block anesthesia in the prostate biopsy
Effect of prostate volume on the peripheral nerve block anesthesia in the prostate biopsy Open
Compared with local anesthesia, ultrasound-guided PNB has superior analgesic effect and equal safety, but for patients with a large prostate volume, the analgesic effect is inefficient.