Explanipedia

[Corrigendum] miR‑335 promotes ferroptosis by targeting ferritin heavy chain 1 in in vivo and in vitro models of Parkinson's disease Open

Xinrong Li, Wenwen Si, Zhan Li, Ye Tian, Xuelei Liu , et al. · 2025

Subsequently to the publication of the above paper, an interested reader drew to the authors' attention that, for the JC‑1 staining experiments shown in Fig. 5F on p. 9, the 'mimic NC' and 'inhibitor' panels appeared to show the same cells…

[Research progress on the manufacturing technology of hollow microneedles]. Open

Shuyun Zhou, Huajian Zhou, Xiaoyu Du, Zhen‐Qiang Yu, Tongle Xu , et al. · 2025

Drug administration via hollow microneedles (HMN) have the advantages of painlessness, avoidance of first-pass effect, capability of sustained infusion, and no need for professional personnel operation. In addition, HMN can also be applied…

Rice Responses to Abiotic Stress: Key Proteins and Molecular Mechanisms Open

Xiaohui Wang, Xuelei Liu, Yonglin Su, Huaizong Shen · 2025

The intensification of global climate change and industrialization has exacerbated abiotic stresses on crops, particularly rice, posing significant threats to food security and human health. The mechanisms by which rice responds to these s…

Short-Term Power Load Forecasting Based on DE-IHHO Optimized BiLSTM Open

Xuelei Liu, Ziqi Ma, Hanrui Guo, Yedong Xu, Yingli Cao · 2024

Accurate short-term power load forecasting is the key to determining the grid company’s dispatch plan and system operation mode. Aiming at the problem of low prediction accuracy due to the difficulty in selecting hyperparameters of BiLSTM,…

FRAD: Front-Running Attacks Detection on Ethereum using Ternary Classification Model Open

Yuheng Zhang, Liu Pin, Guojun Wang, Peiqiang Li, Wanyi Gu , et al. · 2023

With the evolution of blockchain technology, the issue of transaction security, particularly on platforms like Ethereum, has become increasingly critical. Front-running attacks, a unique form of security threat, pose significant challenges…

Preparation and physicochemical properties of biochar from the pyrolysis of pruning waste of typical fruit tree in north China Open

Xuelei Liu, Xueyong Ren, Jiangchuan Dong, Bowei Wang, Jian‐Li Gao , et al. · 2023

Routine maintenance of fruit trees generates a substantial quantity of pruning waste each year. This waste is potential feedstock for producing energy, materials, and other products. The feasibility of making biochar from the waste via pyr…

Properties of Slurry Shield Tunnel Sand and Its Application in Large Flow Concrete Open

Ba Hezhuoli Ke Zierkailedi, Libo Bian, Xiufang Wang, Xingbo Hu, Xuelei Liu , et al. · 2022

The amount of Slurry shield tunnel slag (SSTS) from the Beijing East Sixth Ring Road renovation project is about 3 million m3, and it is mainly fine and silt sand. In order to realize its resource utilization, the properties of SSTS and th…

Cryo-EM structure and electrophysiological characterization of ALMT from Glycine max reveal a previously uncharacterized class of anion channels Open

Qin Li, Linghui Tang, Jiashu Xu, Xianhui Zhang, Yun Zhu , et al. · 2022

Aluminum-activated malate transporters (ALMTs) form an anion channel family that plays essential roles in diverse functions in plants. Arabidopsis ALMT12, also named QUAC1 (quick anion channel 1), regulates stomatal closure in response to …

Ccp1-Ndc80 switch at the N terminus of CENP-T regulates kinetochore assembly Open

Qianhua Dong, Xuelei Liu, Xiaohui Wang, Yu Zhao, Yuhang Chen , et al. · 2021

Significance Precise chromosome segregation relies on kinetochores. How kinetochores are precisely assembled on centromeres through the cell cycle remains poorly understood. Centromeres in most eukaryotes are epigenetically marked by nucle…

Molecular basis for the R-type anion channel QUAC1 activity in guard cells Open

Qin Li, Linghui Tang, Jiashu Xu, Xianhui Zhang, Yun Zhu , et al. · 2021

SUMMARY The rapid (R)-type anion channel plays a central role in controlling stomatal closure in plant guard cells, thus regulating the exchange of water and photosynthetic gas (CO 2 ) in response to environmental stimuli. The activity of …

Moxibustion Protects Dopaminergic Neurons in Parkinson’s Disease through Antiferroptosis Open

Zifeng Huang, Wenwen Si, Xinrong Li, Shanyu Ye, Xuelei Liu , et al. · 2021

Ferroptosis is associated with neural degeneration of dopaminergic neurons in Parkinson’s disease (PD). However, how to control the level of ferroptosis in PD remains unclear. Clinically, moxibustion has been used to treat PD and has an ap…

miR‑335 promotes ferroptosis by targeting ferritin heavy chain 1 in in vivo and in vitro models of Parkinson's disease Open

Xinrong Li, Wenwen Si, Zhan Li, Ye Tian, Xuelei Liu , et al. · 2021

Parkinson's disease (PD) is a neurodegenerative disease characterized by the selective loss of dopaminergic neurons in the substantia nigra (SN). In a previous study, the authors demonstrated that ferritin heavy chain 1 (FTH1) inhibited fe…

FTH1 Inhibits Ferroptosis Through Ferritinophagy in the 6-OHDA Model of Parkinson's Disease Open

Ye Tian, Juan Lü, Xiaoqian Hao, Hang Li, Guiyu Zhang , et al. · 2020

Dissecting the underlying pharmaceutical mechanism of Danggui Buxue decoction acting on idiopathic pulmonary fibrosis with network pharmacology Open

Caiping Zhao, Hang Li, Xiaohong Liu, Shuang Liang, Xuelei Liu , et al. · 2020

Backgroud: Danggui Buxue decoction (DBD), a classical prescription in traditional Chinese medicine, has been found to have protective effect on bleomycin-induced pulmonary fibrosis in rats by reducing alveolar inflammation and fibrosis. Ho…

Study on the Temporary Storage Method of Hazardous Chemical Waste in Laboratories of Peking University Open

Xuelei Liu, Mingquan Lv, Feng Pan · 2020

The Effects of Bio-inspired Electromagnetic Fields on Healthy Enhancement with Case Studies Open

Shujun Zhang, Mike Clark, Xuelei Liu, Donghui Chen, Paula Thomas , et al. · 2019

In this paper, an innovative bionic system will be presented. This system can be used to generate bio-inspired electromagnetic fields (BIEFM) by mimicking natural Earth magnetic fields, the frequencies, strengths and waveforms of body orga…

Moxibustion Exerts a Neuroprotective Effect through Antiferroptosis in Parkinson’s Disease Open

Juan Lu, Xuelei Liu, Ye Tian, Hang Li, Zhenxing Ren , et al. · 2019

The objective of this study was to explore the neuroprotective effect of moxibustion on rats with Parkinson’s disease (PD) and its mechanism. A Parkinson’s disease model was established in rats using a two-point stereotactic 6-hydroxydopam…

Hydrogen‑rich solution against myocardial injury and aquaporin expression via the PI3K/Akt signaling pathway during cardiopulmonary bypass in rats Open

Dandan Song, Xuelei Liu, Yugang Diao, Yingjie Sun, Guang-Jie Gao , et al. · 2018

Myocardial ischemia, hypoxia and reperfusion injury are induced by aortic occlusion, cardiac arrest and resuscitation during cardiopulmonary bypass (CPB), which can severely affect cardiac function. The aim of the present study was to inve…

Cold exposure induced oxidative stress and apoptosis in the myocardium by inhibiting the Nrf2-Keap1 signaling pathway Open

Peifang Cong, Yunen Liu, Nannan Liu, Yubiao Zhang, Changci Tong , et al. · 2018

The Role of miRNA-132 against Apoptosis and Oxidative Stress in Heart Failure Open

Xuelei Liu, Zhou Tong, Keyan Chen, Xiaofang Hu, Hongxu Jin , et al. · 2018

Objective . To explore the effect of microRNA-132 of heart failure and provide theoretical guidance for clinical treatment of heart failure (HF). Methods . Peripheral blood was collected from HF patients. RT-qPCR was used to determine micr…

EGCG Maintains Th1/Th2 Balance and Mitigates Ulcerative Colitis Induced by Dextran Sulfate Sodium through TLR4/MyD88/NF-κB Signaling Pathway in Rats Open

Xue Bing, Xuelei Liu, Wanwei Dong, Linlang Liang, Keyan Chen · 2017

Objective. To observe the protective effect of epigallocatechin gallate (EGCG) on dextran sulfate sodium- (DSS-) induced ulcerative colitis in rats and to explore the roles of TLR4/MyD88/NF- κ B signaling pathway. Methods. Rat models of ul…

Increased Expression of TGF-β1 in Correlation with Liver Fibrosis during Echinococcus granulosus Infection in Mice Open

Yumei Liu, Gulizhaer Abudounnasier, Taochun Zhang, Xuelei Liu, Qian Wang , et al. · 2016

To investigate the potential role of transforming growth factor (TGF)-β1 in liver fibrosis during Echinococcus granulosus infection, 96 BALB/c mice were randomly divided into 2 groups, experimental group infected by intraperitoneal injecti…

Bioinformatic prediction of the antigenic epitopes of recombinant ferritin of Echinococcus granulosus Open

Xuelei Liu, Hui Zhao, Wenyan Cao, Yumei Liu, Chuntao Zhang , et al. · 2015

Echinococcosis is a zoonotic parasitic disease affecting humans and other mammals, which is mainly caused Echinococcus at larval stages. It is predominantly endemic in Chinese pasture regions, including Xinjiang, Qinghai, Gansu and Ningxia…

The Effects of Environment Parameter on the Decay of Total Residual Oxidant in Neutral Electrolyzed Sea Water Open

Dongxia Duan, Ping Yao, Guangzhou Liu, Xuelei Liu, Hui Ding · 2015

The introduction of invasive marine species into new environments by the ballast water of ships has been identified as one of the four greatest threats to the world's oceans.Many technologies have been developed for ballast water treatment…

Combined Electrocoagulation, Electrolysis and Photocatalysis Technologies Applied to Ship Sewage Treatment Open

Yu Qing, Yu Hang, Xuelei Liu, Hui Wang, Xu Shu · 2015

To develop new ship sewage treatment method, an electrochemical treatment device combined technologies of electrocoagulation, electrolyzing and photocatalysis was utilized to treat the stimulated ship sewage.The experimental showed that th…

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