Xueping Yao
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View article: Transcriptomics Reveals the Inhibitory Effect of Scutellarin on PRRSV-Infected PAMs
Transcriptomics Reveals the Inhibitory Effect of Scutellarin on PRRSV-Infected PAMs Open
Porcine reproductive and respiratory syndrome (PRRS) is a highly contagious epidemic caused by the porcine reproductive and respiratory syndrome virus (PRRSV). Characterized by reproductive disorders in pregnant sows and respiratory sympto…
View article: Isolation, Identification, and Antibiotic Resistance, CRISPR System Analysis of Escherichia coli from Forest Musk Deer in Western China
Isolation, Identification, and Antibiotic Resistance, CRISPR System Analysis of Escherichia coli from Forest Musk Deer in Western China Open
Escherichia coli (E. coli) is an opportunistic pathogen widely distributed in nature, and multi-drug resistance (MDR) E. coli has been widely recognized as a critical reservoir of resistance genes, posing severe health threats to humans an…
View article: Gut microbiota regulates hepatic ketogenesis and lipid accumulation in ketogenic diet-induced hyperketonemia by disrupting bile acid metabolism
Gut microbiota regulates hepatic ketogenesis and lipid accumulation in ketogenic diet-induced hyperketonemia by disrupting bile acid metabolism Open
The ketogenic diet (KD) induces prolonged hyperketonemia, characterized by elevated circulating level of β-hydroxybutyrate. However, the KD can negatively affect host metabolic health by altering the gut microbial community. Despite this, …
View article: Expression Profiles of lncRNAs and mRNAs in the Mouse Brain Infected with Pseudorabies Virus: A Bioinformatic Analysis
Expression Profiles of lncRNAs and mRNAs in the Mouse Brain Infected with Pseudorabies Virus: A Bioinformatic Analysis Open
Pseudorabies virus (PRV) is a pathogen that causes severe neurological dysfunction in the host, leading to extensive neuronal damage and inflammation. Despite extensive research on the neuropathogenesis of α-herpesvirus infections, many sc…
View article: The Positive Regulatory Effect of DBT on Lipid Metabolism in Postpartum Dairy Cows
The Positive Regulatory Effect of DBT on Lipid Metabolism in Postpartum Dairy Cows Open
Background/Objectives: The transition from a non-lactating to a lactating state is a critical period for lipid metabolism in dairy cows. Danggui Buxue Tang (DBT), stimulating energy metabolism, ameliorates diseases related to lipid metabol…
View article: Alteration of Fecal Microbiota, Fecal Metabolites, and Serum Metabolites in Dairy Cows with Pre-Retained Placenta
Alteration of Fecal Microbiota, Fecal Metabolites, and Serum Metabolites in Dairy Cows with Pre-Retained Placenta Open
Retained placenta (RP) affects lactation and fertility in dairy cows and causes economic losses to the dairy industry. Therefore, screening for early warning of this disease is important. This study used multi omics techniques to reveal th…
View article: Screening for potential warning biomarkers in cows with ketosis based on host–microbiota co-metabolism analysis
Screening for potential warning biomarkers in cows with ketosis based on host–microbiota co-metabolism analysis Open
Introduction The risk of ketosis is assessed by monitoring changes in plasma metabolites and cow behavior during the peripartum period. However, little is known about changes in the fecal bile acid and microbiota of cows before parturition…
View article: Corrigendum: Isolation, identification, recombination analysis and pathogenicity experiment of a PRRSV recombinant strain in Sichuan Province, China
Corrigendum: Isolation, identification, recombination analysis and pathogenicity experiment of a PRRSV recombinant strain in Sichuan Province, China Open
[This corrects the article DOI: 10.3389/fmicb.2024.1362471.].
View article: Isolation, identification, recombination analysis and pathogenicity experiment of a PRRSV recombinant strain in Sichuan Province, China
Isolation, identification, recombination analysis and pathogenicity experiment of a PRRSV recombinant strain in Sichuan Province, China Open
Since 2013, the porcine reproductive and respiratory syndrome virus type 2 (PRRSV-2), lineage 1.8 (NADC30-like PRRSV) has emerged and become widely prevalent in China. The NADC30-like PRRSV poses significant challenges for disease control,…
View article: Bombesin receptor-activated protein homolog deficiency altered the pattern of pathological changes of psoriasis - like skin lesion in mice
Bombesin receptor-activated protein homolog deficiency altered the pattern of pathological changes of psoriasis - like skin lesion in mice Open
This study investigated the potential role of the mouse homolog of bombesin receptor-activated protein (BRAP) in imiquimod (IMQ) induced psoriasis - like skin inflammation. The expression of both human BRAP, encoded by C6orf89, and …
View article: Epidemiological investigation and pathogenicity of porcine reproductive and respiratory syndrome virus in Sichuan, China
Epidemiological investigation and pathogenicity of porcine reproductive and respiratory syndrome virus in Sichuan, China Open
Porcine reproductive and respiratory syndrome virus type 2 (PRRSV-2) lineage 8 was first detected in mainland China in 2006 and has since rapidly spread to become the primary epidemic strain in the country. In this study, samples such as l…
View article: HDAC2 Inhibits Hippocampal Neurogenesis and Impairs the Cognitive Function in Prenatally Stressed Adult Offspring
HDAC2 Inhibits Hippocampal Neurogenesis and Impairs the Cognitive Function in Prenatally Stressed Adult Offspring Open
The objective of this study was to investigate the mechanism of prenatal stress on the cognitive function of offspring, and clarify the change of histone deacetylase 2 (HDAC2) expression in hippocampal neurons of offspring.16 pregnant SD r…
View article: Development of a Real-Time TaqMan RT-PCR Assay for the Detection of NADC34-like Porcine Reproductive and Respiratory Syndrome Virus
Development of a Real-Time TaqMan RT-PCR Assay for the Detection of NADC34-like Porcine Reproductive and Respiratory Syndrome Virus Open
NADC34-like porcine reproductive and respiratory syndrome virus first appeared in 2017 in a herd of pigs in Liaoning Province, China. The virus was subsequently found in other provinces. Given the potential for this virus to cause an epide…
View article: Association between Tryptophan Metabolism and Inflammatory Biomarkers in Dairy Cows with Ketosis
Association between Tryptophan Metabolism and Inflammatory Biomarkers in Dairy Cows with Ketosis Open
Dairy cows with ketosis have high circulating beta-hydroxybutyric acid (BHBA) concentrations alongside which inflammation is concomitantly developed. Tryptophan (Trp) is an essential amino acid that participates in the regulation of the in…
View article: Moleculer cloning, prokaryotic expression and its application potential evaluation of interferon (IFN)-ω of forest musk deer
Moleculer cloning, prokaryotic expression and its application potential evaluation of interferon (IFN)-ω of forest musk deer Open
Forest musk deer ( Moschus berezovskii ) are currently a threatened species under conservation, and the development of captive populations is restricted by health problems. To evaluate the application potential of interferon (IFN)-ω in the…
View article: Lack of bombesin receptor-activated protein homologous protein impairs hippocampal synaptic plasticity and promotes chronic unpredictable mild stress induced behavioral changes in mice
Lack of bombesin receptor-activated protein homologous protein impairs hippocampal synaptic plasticity and promotes chronic unpredictable mild stress induced behavioral changes in mice Open
Bombesin receptor-activated protein (BRAP) and its homologous protein in mice, which is encoded by bc004004 gene, were expressed abundantly in brain tissues with unknown functions. We treated bc004004-/- mice with …
View article: Modulating gut microbiota and metabolites with dietary fiber oat β-glucan interventions to improve growth performance and intestinal function in weaned rabbits
Modulating gut microbiota and metabolites with dietary fiber oat β-glucan interventions to improve growth performance and intestinal function in weaned rabbits Open
The effect of oat β-glucan on intestinal function and growth performance of weaned rabbits were explored by multi-omics integrative analyses in the present study. New Zealand White rabbits fed oat β-glucan [200 mg/kg body weight (BW)] for …
View article: The Pathogenicity comparison of RHDV and RHDV2 in China by using relative quantitative assay
The Pathogenicity comparison of RHDV and RHDV2 in China by using relative quantitative assay Open
Rabbit hemorrhagic disease virus (RHDV) belongs to Lagovirus in the Caliciviridae family. RHDV is an acute, septic, and highly lethal disease in rabbits. RHDV2, a new variant of RHDV, caused explosive mortality in rabbits of all ages in Si…
View article: Detection of a new emerging strain of rabbit haemorrhagic disease virus 2 (GI.2) in China
Detection of a new emerging strain of rabbit haemorrhagic disease virus 2 (GI.2) in China Open
Introduction In May 2020, an outbreak of rabbit haemorrhagic disease 2 (RHD2) caused by the rabbit haemorrhagic disease virus 2 (RHDV2, GI.2) occurred in Sichuan, China. The acute onset and short disease course resulted in rabbit mortality…
View article: Lack of bombesin receptor–activated protein attenuates bleomycin-induced pulmonary fibrosis in mice
Lack of bombesin receptor–activated protein attenuates bleomycin-induced pulmonary fibrosis in mice Open
Bombesin receptor–activated protein (BRAP) was found to express in the interstitial cells of human fibrotic lungs with unknown function. Its homologous protein, encoded by BC004004 gene, was also present in mouse lung tissues. We used BC00…
View article: The Antiviral Effect of Isatis Root Polysaccharide against NADC30-like PRRSV by Transcriptome and Proteome Analysis
The Antiviral Effect of Isatis Root Polysaccharide against NADC30-like PRRSV by Transcriptome and Proteome Analysis Open
(1) Background: In recent years, the porcine reproductive and respiratory syndrome virus (PRRSV) has become a virulent pathogen that has caused devastating diseases and economic losses worldwide in the swine industry. IRPS has attracted ex…
View article: Development of a real-time TaqMan PCR assay for the detection of porcine circovirus 4
Development of a real-time TaqMan PCR assay for the detection of porcine circovirus 4 Open
Introduction Porcine circovirus 4 (PCV4) was first discovered in 2019 in a herd of pigs with porcine respiratory disease, dermatitis and nephropathy syndrome in Hunan Province, China. It has subsequently been detected in other provinces an…
View article: Lack of bombesin receptor-activated protein homologous protein impairs hippocampal synaptic plasticity and promotes chronic unpredictable mild stress induced behavioral changes in mice
Lack of bombesin receptor-activated protein homologous protein impairs hippocampal synaptic plasticity and promotes chronic unpredictable mild stress induced behavioral changes in mice Open
Bombesin receptor-activated protein (BRAP) and its homologous protein in mice, which is encoded by bc004004 gene, were expressed abundantly in brain tissues with unknown functions. We treated bc004004-/- mice with …
View article: Investigation and molecular identification of <i>Eimeria</i> sp. sampled from captive forest musk deer
Investigation and molecular identification of <i>Eimeria</i> sp. sampled from captive forest musk deer Open
Forest musk deer ( Moschus berezovskii ) is an endangered, protected species in China. Intestinal coccidiosis is a significant problem for captive forest musk deer. However, there are few reports on the prevalence and molecular characteris…
View article: Reference gene screening for analyzing gene expression in the heart, liver, spleen, lung and kidney of forest musk deer
Reference gene screening for analyzing gene expression in the heart, liver, spleen, lung and kidney of forest musk deer Open
The screening of reference genes for real-time quantitative PCR (qPCR) in forest musk deer (FMD) tissue is of great significance to the basic research on FMD. However, there are few reports on the stability analysis of FMD reference genes …
View article: First report on molecular identification of Eimeria sp. from captive forest musk deer
First report on molecular identification of Eimeria sp. from captive forest musk deer Open
Background: Forest musk deer ( Moschus berezovskii ) is a national first-level protected and endangered wild animals in China. The intestinal coccidiosis of captive forest musk deer is one of the most important diseases. However, few studi…
View article: Prenatal Stress Up-Regulated Hippocampal Glucocorticoid Receptor Expression in Female Adult Rat Offspring
Prenatal Stress Up-Regulated Hippocampal Glucocorticoid Receptor Expression in Female Adult Rat Offspring Open
Accumulating evidence from preclinical and clinical studies indicates prenatal exposure to stress or excess glucocorticoids can affect offspring brain. Glucocorticoid receptor (GR) is an important target of glucocorticoid. Therefore the ai…
View article: Effects of compound probiotics on the weight, immunity performance and fecal microbiota of forest musk deer
Effects of compound probiotics on the weight, immunity performance and fecal microbiota of forest musk deer Open
Probiotics are intended to provide health benefits when consumed, generally by improving or restoring the gut flora. The health problems of forest musk deer (FMD, Moschus berezovskii ), a threatened species currently under conservation, re…
View article: The Application of Barrier-Based Learning (BBL) Method in Histology Learning from China
The Application of Barrier-Based Learning (BBL) Method in Histology Learning from China Open
Histology belongs to the discipline of medical morphology. The knowledge is scattered and abstract in this discipline. It is difficult to the medical students beginner. Leading to poor effect on histology teaching. This study aimed to intr…
View article: A Novel Capillary Electrophoresis-Based High-Throughput Multiplex Polymerase Chain Reaction System for the Simultaneous Detection of Nine Pathogens in Swine
A Novel Capillary Electrophoresis-Based High-Throughput Multiplex Polymerase Chain Reaction System for the Simultaneous Detection of Nine Pathogens in Swine Open
Here we aimed to develop a capillary electrophoresis-based high-throughput multiplex polymerase chain reaction (PCR) system for the simultaneous detection of nine pathogens in swine. Nine pairs of specific primers and a set of universal pr…