Xueqing Wang
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View article: Correction: Research hotspots and frontiers of acceptance and commitment therapy for mental disorders: a bibliometric analysis
Correction: Research hotspots and frontiers of acceptance and commitment therapy for mental disorders: a bibliometric analysis Open
[This corrects the article DOI: 10.3389/fpsyt.2025.1440755.].
View article: The recent progress of tumor cell-derived exosomes in the pathogenesis, diagnosis and therapeutic strategies of tumors
The recent progress of tumor cell-derived exosomes in the pathogenesis, diagnosis and therapeutic strategies of tumors Open
Exosomes are extracellular vesicles of nanoscale, which represent the characteristics of the cells of origin. Tumor cell-derived exosomes (TEXs) obtain the characteristics of the tumor cells, which meanwhile transfer the various substances…
View article: The disruption of COPII vesicles activates HSF-1 through SEC-23
The disruption of COPII vesicles activates HSF-1 through SEC-23 Open
HSF-1 is a highly conserved transcription factor that plays a central role in protecting organisms from diverse cellular stresses. However, the mechanisms by which HSF-1 senses and responds to different types of stress remain incompletely …
View article: Systemic immune-inflammatory complex index as a novel predictor of sepsis prognosis: a retrospective cohort study using MIMIC-IV
Systemic immune-inflammatory complex index as a novel predictor of sepsis prognosis: a retrospective cohort study using MIMIC-IV Open
Purpose Sepsis is a life-threatening condition with high mortality and morbidity, making its early detection is critical. Current diagnosis relies on the Sequential [sepsis-related] Organ Failure Assessment score, which is complex and time…
View article: On-site biosignal amplification using a single high-spin conjugated polymer
On-site biosignal amplification using a single high-spin conjugated polymer Open
View article: The Quadruple Gene Mutant ( AER A- Ahh 1- Rtx A- Th ) of a Eromonas Dhakensis Shows Reduced Virulence and Promising Vaccine Development Potential
The Quadruple Gene Mutant ( AER A- Ahh 1- Rtx A- Th ) of a Eromonas Dhakensis Shows Reduced Virulence and Promising Vaccine Development Potential Open
View article: Preparation and Properties of Phenolphthalein-Based Polysulfate Ultrafiltration Membranes
Preparation and Properties of Phenolphthalein-Based Polysulfate Ultrafiltration Membranes Open
View article: Bisphosphonate-mineralized nano-IFNγ suppresses residual tumor growth caused by incomplete radiofrequency ablation through metabolically remodeling tumor-associated macrophages
Bisphosphonate-mineralized nano-IFNγ suppresses residual tumor growth caused by incomplete radiofrequency ablation through metabolically remodeling tumor-associated macrophages Open
Rationale: Radiofrequency ablation (RFA), as a minimally invasive surgery strategy based on local thermal-killing effect, is widely used in the clinical treatment of multiple solid tumors. Nevertheless, RFA cannot achieve the comple…
View article: Synthesis and in vitro oral anti-inflammatory activity of pH-sensitive baicalin liposomes
Synthesis and in vitro oral anti-inflammatory activity of pH-sensitive baicalin liposomes Open
In recent years, clinicians have faced significant challenges in applying baicalin. This issue primarily arises from its low solubility and brief half-life. Thus, developing new baicalin drug delivery system has become an urgent task to ad…
View article: Engineering supramolecular peptide nanofibers for in vivo platelet-hitchhiking beyond ligand-receptor recognition
Engineering supramolecular peptide nanofibers for in vivo platelet-hitchhiking beyond ligand-receptor recognition Open
Ex vivo or in vivo cell-hitchhiking has emerged as a potential means for efficient drug delivery and various disease therapies. However, many challenges remain, such as the complicated engineering process and dependence on ligand-receptor …
View article: Sequential responsive nano-PROTACs for precise intracellular delivery and enhanced degradation efficacy in colorectal cancer therapy
Sequential responsive nano-PROTACs for precise intracellular delivery and enhanced degradation efficacy in colorectal cancer therapy Open
PROteolysis TArgeting Chimeras (PROTACs) have been considered the next blockbuster therapies. However, due to their inherent limitations, the efficacy of PROTACs is frequently impaired by limited tissue penetration and particularly insuffi…
View article: Sputum microbe community alterations induced by long-term inhaled corticosteroid use are associated with airway function in chronic obstructive pulmonary disease patients based on metagenomic next-generation sequencing (mNGS)
Sputum microbe community alterations induced by long-term inhaled corticosteroid use are associated with airway function in chronic obstructive pulmonary disease patients based on metagenomic next-generation sequencing (mNGS) Open
Objective: Inhaled corticosteroids (ICS) are widely used in chronic obstructive pulmonary disease (COPD) patients as a treatment option. However, ICS may also increase the risk of pneumonia and alter the composition of airway microbiota. I…
View article: Copper homeostasis dysregulation in respiratory diseases: a review of current knowledge
Copper homeostasis dysregulation in respiratory diseases: a review of current knowledge Open
Cu is an essential micronutrient for various physiological processes in almost all human cell types. Given the critical role of Cu in a wide range of cellular processes, the local concentrations of Cu and the cellular distribution of Cu tr…
View article: Novel Roles of the Greatwall Kinase Rim15 in Yeast Oxidative Stress Tolerance through Mediating Antioxidant Systems and Transcriptional Regulation
Novel Roles of the Greatwall Kinase Rim15 in Yeast Oxidative Stress Tolerance through Mediating Antioxidant Systems and Transcriptional Regulation Open
The Greatwall-family protein kinase Rim15 is associated with the nutrient starvation response, whereas its role in oxidative stress responses remains unclear. Here, acetic acid and peroxide were used as two oxidative stress elicitors. The …
View article: Tissue-specific profiling of age-dependent miRNAomic changes in Caenorhabditis elegans
Tissue-specific profiling of age-dependent miRNAomic changes in Caenorhabditis elegans Open
Ageing exhibits common and distinct features in various tissues, making it critical to decipher the tissue-specific ageing mechanisms. MiRNAs are essential regulators in ageing and are recently highlighted as a class of intercellular messe…
View article: Molecular Mechanisms of Intracellular Delivery of Nanoparticles Monitored by an Enzyme-Induced Proximity Labeling
Molecular Mechanisms of Intracellular Delivery of Nanoparticles Monitored by an Enzyme-Induced Proximity Labeling Open
View article: Imaging of brain clearance pathways via MRI assessment of the glymphatic system
Imaging of brain clearance pathways via MRI assessment of the glymphatic system Open
Glymphatic clearance dysfunction may play an important role in a variety of neurodegenerative diseases and the progression of ageing. However, in vivo imaging of the glymphatic system is challenging. In this study, we describe an MR…
View article: A Polyamidoamine-Based Electrochemical Aptasensor for Sensitive Detection of Ochratoxin A
A Polyamidoamine-Based Electrochemical Aptasensor for Sensitive Detection of Ochratoxin A Open
Sensitive detection of ochratoxin A (OTA) is significant and essential because OTA may pose risks to human and animal health. Here, we developed an electrochemical aptasensor for OTA analysis using polyamidoamine (PAMAM) dendrimers as a si…
View article: Boosting synergism of chemo- and immuno-therapies via switching paclitaxel-induced apoptosis to mevalonate metabolism-triggered ferroptosis by bisphosphonate coordination lipid nanogranules
Boosting synergism of chemo- and immuno-therapies via switching paclitaxel-induced apoptosis to mevalonate metabolism-triggered ferroptosis by bisphosphonate coordination lipid nanogranules Open
View article: Intelligent road safety system based on multi-function warning device
Intelligent road safety system based on multi-function warning device Open
This paper proposes a road driving warning device, including support rods and warning plates. Several display screens are installed on one side of the warning panel. Indication light balls are set on the display screen. Warning board top f…
View article: Advances in Sol-Gel-Based Superhydrophobic Coatings for Wood: A Review
Advances in Sol-Gel-Based Superhydrophobic Coatings for Wood: A Review Open
As the focus of architecture, furniture, and other fields, wood has attracted extensive attention for its many advantages, such as environmental friendliness and excellent mechanical properties. Inspired by the wetting model of natural lot…
View article: An ultrasensitive method for detecting mutations from short and rare cell-free DNA
An ultrasensitive method for detecting mutations from short and rare cell-free DNA Open
Background Cell-free DNA (cfDNA) promises to serve as surrogate biomarkers for non-invasive molecular diagnostics. Disease-specific cfDNA, such as circulating tumor DNA (ctDNA), was short and rare, making the detection performance of the c…
View article: Tissue-specific profiling of age-dependent miRNAomic changes in Caenorhabditis elegans
Tissue-specific profiling of age-dependent miRNAomic changes in Caenorhabditis elegans Open
Ageing in various tissues exhibits common and distinct features. It is critical to decipher the mechanisms underlying ageing in individual tissues. MicroRNAs (miRNAs) are essential regulators in ageing and are recently highlighted as a new…
View article: IgG Fc Affinity Ligands and Their Applications in Antibody-Involved Drug Delivery: A Brief Review
IgG Fc Affinity Ligands and Their Applications in Antibody-Involved Drug Delivery: A Brief Review Open
Antibodies are not only an important class of biotherapeutic drugs, but also are targeting moieties for achieving active targeting drug delivery. Meanwhile, the rapidly increasing application of antibodies and Fc-fusion proteins has inspir…
View article: Ethical conflict in nursing: A concept analysis
Ethical conflict in nursing: A concept analysis Open
Aims and Objectives The purpose of this paper was to clarify the concept of ethical conflict in nursing and highlight the importance of tackling this issue. Background Ethical conflict is on the rise in the nursing context. It is associate…
View article: Integrative Serum Metabolic Fingerprints Based Multi‐Modal Platforms for Lung Adenocarcinoma Early Detection and Pulmonary Nodule Classification
Integrative Serum Metabolic Fingerprints Based Multi‐Modal Platforms for Lung Adenocarcinoma Early Detection and Pulmonary Nodule Classification Open
Identification of novel non‐invasive biomarkers is critical for the early diagnosis of lung adenocarcinoma (LUAD), especially for the accurate classification of pulmonary nodule. Here, a multiplexed assay is developed on an optimized nanop…
View article: An enzyme-responsive and transformable PD-L1 blocking peptide-photosensitizer conjugate enables efficient photothermal immunotherapy for breast cancer
An enzyme-responsive and transformable PD-L1 blocking peptide-photosensitizer conjugate enables efficient photothermal immunotherapy for breast cancer Open
View article: Trimming nano delivery at the cell side by tuning ARF6 GTPases to the GTP-bound form
Trimming nano delivery at the cell side by tuning ARF6 GTPases to the GTP-bound form Open
Intracellular delivery crossing the endomembrane barrier is the “last mile to target” for nano delivery systems carrying biomacromolecules, including genetic medicines. Nevertheless, a mass of nanomedicines is currently restricted by their…
View article: Optimize the combination regimen of Trastuzumab and Nab-paclitaxel in HER2-positive tumors via modulating Caveolin-1 expression by lovastatin
Optimize the combination regimen of Trastuzumab and Nab-paclitaxel in HER2-positive tumors via modulating Caveolin-1 expression by lovastatin Open
View article: Catalytic Synthesis of 5-Fluoro-2-oxazolines: Using BF<sub>3</sub>·Et<sub>2</sub>O as the Fluorine Source and Activating Reagent
Catalytic Synthesis of 5-Fluoro-2-oxazolines: Using BF<sub>3</sub>·Et<sub>2</sub>O as the Fluorine Source and Activating Reagent Open
Hypervalent iodine catalyst-catalyzed nucleophilic fluorination of unsaturated amides using BF3·Et2O as the fluorine source and activating reagent was reported. Various 5-fluoro-2-oxazoline derivatives were synthesize…