Wei Xiang
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View article: A hybrid approach combining Bayesian networks and logistic regression for enhancing risk assessment
A hybrid approach combining Bayesian networks and logistic regression for enhancing risk assessment Open
View article: Alisertib impairs the stemness of hepatocellular carcinoma by inhibiting purine synthesis
Alisertib impairs the stemness of hepatocellular carcinoma by inhibiting purine synthesis Open
View article: Mstid-Net: Multi-Scale Hierarchical Semantic Segmentation Network with Soft Attention Feature Fusion for Tea Impurity Detection
Mstid-Net: Multi-Scale Hierarchical Semantic Segmentation Network with Soft Attention Feature Fusion for Tea Impurity Detection Open
View article: Towards High-Resolution Pollutant Mapping in Narrow Spaces: Integrating Fixed Sensors, Mobile Robots, and Enhanced Reconstruction Techniques
Towards High-Resolution Pollutant Mapping in Narrow Spaces: Integrating Fixed Sensors, Mobile Robots, and Enhanced Reconstruction Techniques Open
View article: A novel prognostic model for predicting patient survival and immunotherapy responsiveness in hepatocellular carcinoma: insights into the involvement of T-cell proliferation
A novel prognostic model for predicting patient survival and immunotherapy responsiveness in hepatocellular carcinoma: insights into the involvement of T-cell proliferation Open
Background The cancer-associated biological mechanisms and the implementation of immunotherapy are heavily impacted by the activities of T cells, consequently influencing the effectiveness of therapeutic interventions. Nevertheless, the me…
View article: Targeting PD‐L1 with DNA Aptamers and Conjugated with Gemcitabine as a Novel Therapeutic Strategy for Bladder Cancer Chemotherapy Combined with Immunotherapy
Targeting PD‐L1 with DNA Aptamers and Conjugated with Gemcitabine as a Novel Therapeutic Strategy for Bladder Cancer Chemotherapy Combined with Immunotherapy Open
Cancer Therapy Aptamers have great functions in carrier drug delivery and have broad application prospects in the field of biomedicine. In article number 2300104, Jianye Liu and co-workers report the synthesis of a novel material, PD-L1-GE…
View article: Targeting PD‐L1 with DNA Aptamers and Conjugated with Gemcitabine as a Novel Therapeutic Strategy for Bladder Cancer Chemotherapy Combined with Immunotherapy
Targeting PD‐L1 with DNA Aptamers and Conjugated with Gemcitabine as a Novel Therapeutic Strategy for Bladder Cancer Chemotherapy Combined with Immunotherapy Open
Due to the poor stability and adverse effects of chemotherapy drugs, such as gemcitabine, the current effectiveness of traditional chemotherapy is minimal. Some patients also show a low response rate to immunotherapy. Therefore, a novel ma…
View article: DNA aptamers target PD-L1 and conjugate gemcitabine as a novel therapeutic strategy α β γ chemotherapy combined with immunotherapy for bladder cancer....
DNA aptamers target PD-L1 and conjugate gemcitabine as a novel therapeutic strategy α β γ chemotherapy combined with immunotherapy for bladder cancer.... Open
Due to the poor stability and adverse effects of chemotherapy drugs, such as gemcitabine, the current effectiveness of traditional chemotherapy is minimal. Some patients also show a low response rate to immunotherapy. Therefore, we have de…
View article: Recent advances in aptamer-based therapeutic strategies for targeting cancer stem cells
Recent advances in aptamer-based therapeutic strategies for targeting cancer stem cells Open
Cancer stem cells (CSCs) are believed to be the main cause of chemotherapy resistance and tumor relapse. Various therapeutic strategies to eliminate CSCs have been developed recently. Aptamers, also called "chemical antibodies", can specif…
View article: Targeting treatment of bladder cancer using PTK7 aptamer-gemcitabine conjugate
Targeting treatment of bladder cancer using PTK7 aptamer-gemcitabine conjugate Open
Background Gemcitabine (GEM) is one of the first-line chemotherapies for bladder cancer (BC), but the GEMs cannot recognize cancer cells and have a low long-term response rate and high recurrence rate with side effects during the treatment…
View article: Faddeev fixed-center approximation to the $$D\bar{D}K$$ system and the hidden charm $$K_{c\bar{c}}(4180)$$ state
Faddeev fixed-center approximation to the $$D\bar{D}K$$ system and the hidden charm $$K_{c\bar{c}}(4180)$$ state Open
View article: Carbon emission flow oriented multitasking multi‐objective optimization of electricity‐hydrogen integrated energy system
Carbon emission flow oriented multitasking multi‐objective optimization of electricity‐hydrogen integrated energy system Open
A grid‐connected electricity‐hydrogen integrated energy system (EH‐IES) is proposed here for the cooperative analysis of electricity, heat, cooling and hydrogen energy flows, where carbon emission flow (CEF) is introduced to allocate the c…
View article: Treatment of bladder cancer by geoinspired synthetic chrysotile nanocarrier-delivered <i>circPRMT5</i> siRNA
Treatment of bladder cancer by geoinspired synthetic chrysotile nanocarrier-delivered <i>circPRMT5</i> siRNA Open
Background Circular RNAs (circRNAs) have important functions in many fields of cancer biology. In particular, we previously reported that the oncogenic circRNA, circPRMT5 , has a major role in bladder cancer progression. Therapy based on c…
View article: Generalized Energy Storage Allocation Strategies for Load Aggregator in Hierarchical Electricity Markets
Generalized Energy Storage Allocation Strategies for Load Aggregator in Hierarchical Electricity Markets Open
The uncertainty of user-side resource response will affect the response quality and economic benefit of load aggregator (LA). Therefore, this paper regards the flexible user-side resources as a virtual energy storage (VES), and uses the tr…
View article: Additional file 1 of Effects of nursing support workers participation on negative emotions, quality of life and life satisfaction of patients with cerebral hemorrhage: a quasi-experimental study
Additional file 1 of Effects of nursing support workers participation on negative emotions, quality of life and life satisfaction of patients with cerebral hemorrhage: a quasi-experimental study Open
Additional file 1.
View article: Fe-doped chrysotile nanotubes containing siRNAs to silence SPAG5 to treat bladder cancer
Fe-doped chrysotile nanotubes containing siRNAs to silence SPAG5 to treat bladder cancer Open
View article: SLC12A5 interacts and enhances SOX18 activity to promote bladder urothelial carcinoma progression via upregulating MMP7
SLC12A5 interacts and enhances SOX18 activity to promote bladder urothelial carcinoma progression via upregulating MMP7 Open
Solute carrier family 12 member 5 (SLC12A5) has an oncogenic role in bladder urothelial carcinoma. The present study aimed to characterize the molecular mechanisms of SLC12A5 in bladder urothelial carcinoma pathogenesis. Functional assays …
View article: Dynamic Energy Dispatch in Isolated Microgrids Based on Deep Reinforcement Learning.
Dynamic Energy Dispatch in Isolated Microgrids Based on Deep Reinforcement Learning. Open
This paper focuses on deep reinforcement learning (DRL)-based energy dispatch for isolated microgrids (MGs) with diesel generators (DGs), photovoltaic (PV) panels, and a battery. A finite-horizon Partial Observable Markov Decision Process …
View article: Economic dispatch of power system containing UHVDC with direct power purchase by large consumers
Economic dispatch of power system containing UHVDC with direct power purchase by large consumers Open
With the integration of the ultra‐high‐voltage direct‐current (UHVDC) of large capacity, the scheduled outputs of the power plants are limited, and the direct power purchase (DPP) by large consumers is influenced. The negative impact cause…
View article: Design of Toll Plaza Based on Genetic Algorithm
Design of Toll Plaza Based on Genetic Algorithm Open
This paper studies the design of toll plaza based on genetic algorithm.Based on the idea of the function value of the genetic algorithm, the area of the toll station and the traffic accident rate are taken as the objective function, to fin…