Xuyu Chen
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View article: Protective role of the planetary health diet index against metabolic dysfunction-associated steatotic liver disease: global and individual evidence
Protective role of the planetary health diet index against metabolic dysfunction-associated steatotic liver disease: global and individual evidence Open
Background The rising global epidemic of metabolic dysfunction-associated steatotic liver disease (MASLD), coupled with the urgent need for sustainable food systems, highlights the importance of dietary approaches that support both human w…
View article: Prognostic risk factors analysis of low-grade gastric intraepithelial neoplasia—a single-center follow-up study
Prognostic risk factors analysis of low-grade gastric intraepithelial neoplasia—a single-center follow-up study Open
Objective Low-grade gastric intraepithelial neoplasia (LGIN), as a precancerous lesion of gastric cancer, is of great significance in the prevention and treatment of gastric cancer. In this study, we investigated the risk factors associate…
View article: Identification of differentially expressed genes associated with ferroptosis in ulcerative colitis
Identification of differentially expressed genes associated with ferroptosis in ulcerative colitis Open
Purpose To identify ferroptosis-related genes associated with the development of Ulcerative colitis (UC), through bioinformatics and basic experiments. Methods Ferroptosis-related genes were identified from UC microarray data extracted fro…
View article: Review on the Protective Mechanism of Pueraria Lobata and Hovenia Dulcis Extracts against Alcoholic Liver Injury
Review on the Protective Mechanism of Pueraria Lobata and Hovenia Dulcis Extracts against Alcoholic Liver Injury Open
Alcoholic liver injury is a disease that causes significant harm to the human body and is difficult to cure. Long - term heavy drinking and alcoholism can lead to alcoholic liver injury, triggering physical and mental related diseases, suc…
View article: Infection and Immunodeficiency in Patients With Chronic Kidney Disease: Current Evidence and Potential Preventive Strategies of Chinese Medicine
Infection and Immunodeficiency in Patients With Chronic Kidney Disease: Current Evidence and Potential Preventive Strategies of Chinese Medicine Open
Cardiovascular disease and infections significantly contribute to high mortality and morbidity in patients with chronic kidney disease (CKD). Despite extensive research on cardiovascular complications, infection-related aspects in CKD have…
View article: Combined analysis of the endophytic fungi and volatile oil content of different Aquilaria sinensis germplasms revealed the correlations between endophytic fungal abundances and agarwood production
Combined analysis of the endophytic fungi and volatile oil content of different Aquilaria sinensis germplasms revealed the correlations between endophytic fungal abundances and agarwood production Open
Introduction Agarwood, a prized aromatic resin from Aquilaria sinensis , is formed as a defensive response to injury or fungal infection. However, the factors influencing its chemical composition remain poorly understood. This study aimed …
View article: Anaerobic Digestion of High-Solid Chicken Manure (CM) at Different Temperature: Intestinal Microbiome Efficiency, Inhibition, and Microbial Community Evolution
Anaerobic Digestion of High-Solid Chicken Manure (CM) at Different Temperature: Intestinal Microbiome Efficiency, Inhibition, and Microbial Community Evolution Open
Anaerobic digestion (AD) of high-solid mono-chicken manure (CM) holds great promise for resource utilization. However, the effects of substrate overload (high-solid mixture inside the reactor) on AD performance at various temperatures are …
View article: Pan-cancer analysis of Methyltransferase-like 16 (METTL16) and validated in colorectal cancer
Pan-cancer analysis of Methyltransferase-like 16 (METTL16) and validated in colorectal cancer Open
Human Methyltransferase-like 16(METTL16) is an independent N6-methyladenosine (m6A) methyltransferase. Previous studies have proven METTL16 been linked with some types of cancers. However, comparative studies of the relevance of METTL16 ac…
View article: Analysis of fungal composition in different layers of Bantou agarwood-forming trunk of Aquilaria sinensis revealing presence of Aspergillus-inhibiting substances in agarwood sites
Analysis of fungal composition in different layers of Bantou agarwood-forming trunk of Aquilaria sinensis revealing presence of Aspergillus-inhibiting substances in agarwood sites Open
Agarwood from agarwood formation sites contains potential substances that inhibit Aspergillus, which provides valuable information for the control of the genus of Aspergillus.
View article: The relationship between perceived stress and job burnout of police officers during the COVID-19 pandemic: the mediating role of social support, sleep quality and resilience
The relationship between perceived stress and job burnout of police officers during the COVID-19 pandemic: the mediating role of social support, sleep quality and resilience Open
Perceived stress affects burnout through mediating variables such as social support, sleep quality, and resilience. The mediating effect of sleep quality is the most potent.
View article: Extracts of <i>Portulaca oleracea</i> and <i>Patrinia scabiosaefolia</i> relieve ultraviolet B-induced skin injury in solar dermatitis mice via inhibiting IL-17/CCL2 pathway and oxidative stress
Extracts of <i>Portulaca oleracea</i> and <i>Patrinia scabiosaefolia</i> relieve ultraviolet B-induced skin injury in solar dermatitis mice via inhibiting IL-17/CCL2 pathway and oxidative stress Open
Introduction: Solar dermatitis, a condition triggered by excessive exposure to ultraviolet B (UVB) radiation, results in inflammatory skin damage marked by erythema, edema, and epidermal injury. Portulaca oleracea (PO) and Patrinia …
View article: Diagnostic accuracy of human papillomavirus testing on self-collected samples among women referred for colposcopy
Diagnostic accuracy of human papillomavirus testing on self-collected samples among women referred for colposcopy Open
To assess the diagnostic accuracy of self-collected urine and vaginal samples for the identification of precancerous cervical lesions in the referral population using high-risk human papillomavirus (hrHPV) assays based on polymerase chain …
View article: Efficient removal of polystyrene nanoplastics from complex water system through multiple driving forces with MOF-based composite
Efficient removal of polystyrene nanoplastics from complex water system through multiple driving forces with MOF-based composite Open
View article: Intestinal metaplasia key molecules and UPP1 activation via Helicobacter pylori /NF-kB: drivers of malignant progression in gastric cancer
Intestinal metaplasia key molecules and UPP1 activation via Helicobacter pylori /NF-kB: drivers of malignant progression in gastric cancer Open
View article: Combined analysis of the endophytic fungi and volatile oil content of different Aquilaria sinensis germplasms revealed the correlations between endophytic fungal abundances and agarwood production
Combined analysis of the endophytic fungi and volatile oil content of different Aquilaria sinensis germplasms revealed the correlations between endophytic fungal abundances and agarwood production Open
The aim of this study was to examine the relationships between the endophytic fungi and volatile oil content in ordinary-type and Qinan-type Aquilaria sinensis. High-throughput sequencing was used to analyse the distribution of fungi in th…
View article: Pro-apoptotic gene BAX is a pan-cancer predictive biomarker for prognosis and immunotherapy efficacy
Pro-apoptotic gene BAX is a pan-cancer predictive biomarker for prognosis and immunotherapy efficacy Open
Our findings suggested that BAX can function as an oncogene and may be used as a potential predictive biomarker for prognosis and immunotherapy efficacy of human cancer, which could provide a new approach for cancer therapy.
View article: Diabetes and long duration leading to speech-, low/mid-, and high- frequency hearing loss: current evidence from the China National Health Survey 2023
Diabetes and long duration leading to speech-, low/mid-, and high- frequency hearing loss: current evidence from the China National Health Survey 2023 Open
Purpose To examine the effect of diabetes, duration of diabetes, and blood glucose on speech-, low/mid-, and high-frequency hearing loss. Methods In this cross-sectional study, 2821 participants aged 20–87 years in the China National Healt…
View article: Long non-coding RNA HOTAIR: from pan-cancer analysis to colorectal cancer-related uridine metabolism
Long non-coding RNA HOTAIR: from pan-cancer analysis to colorectal cancer-related uridine metabolism Open
Long non-coding RNAs (lncRNAs) are involved significantly in the development of human cancers. lncRNA HOTAIR has been reported to play an oncogenic role in many human cancers. Its specific regulatory role is still elusive. And it might hav…
View article: Fungal community analysis of two edible herbs: Citri reticulatae pericarpium and polygalae radix
Fungal community analysis of two edible herbs: Citri reticulatae pericarpium and polygalae radix Open
Citri Reticulatae Pericarpium(CRP) and Polygalae Radix (PR) are traditional Chinese medicinal herbs and dietary supplements, and they are commonly included in most prescriptions. Fungal contamination in CRP and PR has long been a concern f…
View article: Deubiquitinase USP19 modulates apoptotic calcium release and endoplasmic reticulum stress by deubiquitinating BAG6 in triple negative breast cancer
Deubiquitinase USP19 modulates apoptotic calcium release and endoplasmic reticulum stress by deubiquitinating BAG6 in triple negative breast cancer Open
Background Triple‐negative breast cancer (TNBC), a heterogeneous subtype of breast cancer (BC), had poor prognosis. Endoplasmic reticulum (ER) stress was responsible for cellular processes and played a crucial role in the cell function. ER…
View article: Isolation of exogenous fungi from Notoginseng Radix et Rhizoma and preliminary analysis of toxigenic fungi
Isolation of exogenous fungi from Notoginseng Radix et Rhizoma and preliminary analysis of toxigenic fungi Open
Notoginseng Radix et Rhizoma (Sanqi in Chinese) is a precious traditional Chinese herbal medicine. It has the effect of dispersing blood stasis and stopping bleeding, reducing swelling and fixing pain. However, it tends to contaminate with…
View article: WHAT IS A SOUNDSCAPE INTERVENTION EXPLORING DEFINITIONS
WHAT IS A SOUNDSCAPE INTERVENTION EXPLORING DEFINITIONS Open
View article: LINC00467: an oncogenic long noncoding RNA
LINC00467: an oncogenic long noncoding RNA Open
Long non-coding RNAs (lncRNAs) have been found to play essential roles in the cell proliferation, fission and differentiation, involving various processes in humans. Recently, there is more and more interest in exploring the relationship b…
View article: Risk for lung-related diseases associated with welding fumes in an occupational population: Evidence from a Cox model
Risk for lung-related diseases associated with welding fumes in an occupational population: Evidence from a Cox model Open
Background Welding fumes are a risk factor for welder pneumoconiosis. However, there is a lack of population information on the occurrence of welding fume-induced lung cancer, and little is known about the welding fume pathogenesis. Method…
View article: Analysis of Fungal Microbiomes in Edible Medicinal Morindae Officinalis Radix and Alpiniae Oxyphyllae Fructus Using DNA Metabarcoding
Analysis of Fungal Microbiomes in Edible Medicinal Morindae Officinalis Radix and Alpiniae Oxyphyllae Fructus Using DNA Metabarcoding Open
Morindae Officinalis Radix (MOR) and Alpiniae Oxyphyllae Fructus (AOF) have been widely used as dietary supplements and traditional herbal medicines for centuries. Fungal and mycotoxin contamination in MOR and AOF has been reported recentl…
View article: Montelukast Performs Synergistic Effect with Carfilzomib in Multiple Myeloma by Inhibiting the Deubiquitinase UCHL1
Montelukast Performs Synergistic Effect with Carfilzomib in Multiple Myeloma by Inhibiting the Deubiquitinase UCHL1 Open
Immunomodulators play an important role in combination chemotherapy of multiple myeloma. Besides, it has been reported that leukotriene-D4 receptors play an important role in carcinogenesis. The current study was carried out to assess the …
View article: The Emerging Roles of LINC00665 in Human Cancers
The Emerging Roles of LINC00665 in Human Cancers Open
Long non-coding RNAs (lncRNAs) are non-coding RNAs that have more than 200 nucleotides and can participate in the regulation of gene expression in various ways. An increasing number of studies have shown that the dysregulated expression of…
View article: Stereotactic Body Radiation Therapy for the First-Line Comprehensive Treatment of Oligometastatic Nasopharyngeal Carcinoma: A Prospective, Single-Arm, Phase II Trial
Stereotactic Body Radiation Therapy for the First-Line Comprehensive Treatment of Oligometastatic Nasopharyngeal Carcinoma: A Prospective, Single-Arm, Phase II Trial Open
View article: Efficacy and safety of apatinib in the treatment of osteosarcoma: a single-arm meta-analysis among Chinese patients
Efficacy and safety of apatinib in the treatment of osteosarcoma: a single-arm meta-analysis among Chinese patients Open
View article: Improved hydrolytic robustness and catalytic performance of flexible lanthanide-based metal-organic frameworks: A matter of coordination environments
Improved hydrolytic robustness and catalytic performance of flexible lanthanide-based metal-organic frameworks: A matter of coordination environments Open
Due to the flexible structures and vulnerable coordination bonds, hydrolytic stability of metal-organic frameworks (MOFs) is a critical issue for practical use. Besides the collapse of MOF structures by water intrusion, herein, we found th…