Y. Ashikhmin
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Analysis of genetic polymorphism associations with cardiometabolic risk factors and phenotypic age in individuals without significant pathology Open
BACKGROUND: Against the background of significant achievements in the treatment and prevention of various diseases, the direction of “medicine for the healthy” currently does not adequately meet the public demand for active longevity. Deve…
Using artificial intelligence to predict and prevent non-cancer mortality in patients with cancer: ARILIS study protocol Open
Aim: To present the ARILIS study aimed at assessing the use of artificial intelligence to analyze chest computed tomography (CT) data to predict and prevent non-cancer mortality in patients with cancer. Material and methods: This cohort st…
Cost-effectiveness analysis of HeartMate3 system in patients with severe chronic heart failure and reduced left ventricular ejection fraction Open
Objective. Cost-effectiveness analysis of HeartMate3 support system and optimal drug therapy in patients with severe chronic heart failure (CHF); to analyze potential impact of HeartMate3 implantation on healthcare budget in the Russian Fe…
View article: The Profile of Circulating Blood microRNAs in Outpatients with Vulnerable and Stable Atherosclerotic Plaques: Associations with Cardiovascular Risks
The Profile of Circulating Blood microRNAs in Outpatients with Vulnerable and Stable Atherosclerotic Plaques: Associations with Cardiovascular Risks Open
Non-coding RNAs reflect many biological processes in the human body, including athero-sclerosis. In a cardiology outpatient department cohort (N = 83), we aimed to compare the levels of circulating microRNAs in groups with vulnerable plaqu…
Anti-CGRP monoclonal antibodies: a breakthrough in the treatment of migraine Open
To date, the prophylactic treatment of migraine has included only nonspecific drugs of various pharmacological groups: the beta-blockers propranolol and metoprolol, the anticonvulsants topiramate and valproic acid, the antidepressants amit…
Possibilities of Computed Tomography of the Heart in Risk Stratification and Determination of Optimal Strategy of Primary Prevention of Cardiovascular Complications of Atherosclerosis Open
Modern strategies of primary prevention of cardiovascular complications of atherosclerotic etiology are presented in this article: traditional approach based on assessment of risk of development of complication and coming to replace it con…
Pharmacoeconomic analysis of the etravirine compared to raltegravir in treatment HIV-infected adult patients, previously treated with antiretroviral drugs Open
Objective: To perform comprehensive pharmacoeconomical assessment of use etravirine and raltegravir in HIV-infected patients. Methodology: Cost-eifectiveness and budget impact analyses of etravirine or raltegravir on the top of optimized b…
Comparative clinical and economic analysis Jodantipyrin for emergency prevention of tick-borne encephalitis Open
Objective: To conduct a comparative pharmacoeconomic analysis Jodantipyrin drugs and Human immunoglobulin against tick-borne encephalitis (TBE) for emergency prevention of tick-borne encephalitis in a health care system of the Russian Fede…