Yousef Bagheri
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View article: The membrane transition strongly enhances biopolymer condensation through prewetting
The membrane transition strongly enhances biopolymer condensation through prewetting Open
Biopolymers that separate into condensed and dilute phases in solution also prewet membranes when one or more components couple to membrane lipids. Here we demonstrate that this prewetting transition becomes exquisitely sensitive to lipid …
View article: Multiplexed sequential imaging in living cells with orthogonal fluorogenic RNA aptamer/dye pairs
Multiplexed sequential imaging in living cells with orthogonal fluorogenic RNA aptamer/dye pairs Open
Detecting multiple targets in living cells is important in cell biology. However, multiplexed fluorescence imaging beyond two-to-three targets remains a technical challenge. Herein, we introduce a multiplexed imaging strategy, ‘sequential …
View article: Multiplexed Sequential Imaging in Living Cells with Orthogonal Fluorogenic RNA Aptamer/Dye Pairs
Multiplexed Sequential Imaging in Living Cells with Orthogonal Fluorogenic RNA Aptamer/Dye Pairs Open
Single-cell detection of multiple target analytes is an important goal in cell biology. However, due to the spectral overlap of common fluorophores, multiplexed fluorescence imaging beyond two-to-three targets inside living cells remains a…
View article: Abstract 2548: Responsive assembly of signaling domains at the plasma membrane
Abstract 2548: Responsive assembly of signaling domains at the plasma membrane Open
View article: Advanced DNA Zipper Probes for Detecting Cell Membrane Lipid Domains
Advanced DNA Zipper Probes for Detecting Cell Membrane Lipid Domains Open
The cell membrane is a complex mixture of lipids, proteins, and other components. By forming dynamic lipid domains, different membrane molecules can selectively interact with each other to control cell signaling. Herein, we report several …
View article: Digging into the biophysical features of cell membranes with lipid-DNA conjugates
Digging into the biophysical features of cell membranes with lipid-DNA conjugates Open
Lipid-DNA conjugates have emerged as highly useful tools to modify the cell membranes. These conjugates generally consist of a lipid anchor for membrane modification and a functional DNA nanostructure for membrane analysis or regulation. T…
View article: Imaging Membrane Order and Dynamic Interactions in Living Cells with a DNA Zipper Probe
Imaging Membrane Order and Dynamic Interactions in Living Cells with a DNA Zipper Probe Open
The cell membrane is a dynamic and heterogeneous structure composed of distinct sub‐compartments. Within these compartments, preferential interactions occur among various lipids and proteins. Currently, it is still challenging to image the…
View article: Quantitative and Multiplexed Fluorescence Lifetime Imaging of Intercellular Tensile Forces
Quantitative and Multiplexed Fluorescence Lifetime Imaging of Intercellular Tensile Forces Open
Mechanical interactions between cells have been shown to play critical roles in regulating cell signaling and communications. However, the precise measurement of intercellular forces is still quite challenging, especially considering the c…
View article: Real Time Monitoring of Transient Lipid-Lipid Interactions on Live Cell Membranes using a DNA Probe
Real Time Monitoring of Transient Lipid-Lipid Interactions on Live Cell Membranes using a DNA Probe Open
View article: Efficient and selective DNA modification on bacterial membranes
Efficient and selective DNA modification on bacterial membranes Open
A lipid-based approach to effectively modify DNA molecules onto various types of bacterial membranes after simple incubation.
View article: Current Methods for Detecting Cell Membrane Transient Interactions
Current Methods for Detecting Cell Membrane Transient Interactions Open
Short-lived cell membrane complexes play a key role in regulating cell signaling and communication. Many of these complexes are formed based on low-affinity and transient interactions among various lipids and proteins. New techniques have …
View article: A Genetically Encoded RNA Photosensitizer for Targeted Cell Regulation
A Genetically Encoded RNA Photosensitizer for Targeted Cell Regulation Open
Genetically encoded RNA devices have emerged for various cellular applications in imaging and biosensing, but their functions as precise regulators in living systems are still limited. Inspired by protein photosensitizers, we propose here …
View article: Quantitative Assessment of the Dynamic Modification of Lipid-DNA Probes on Live Cell Membranes
Quantitative Assessment of the Dynamic Modification of Lipid-DNA Probes on Live Cell Membranes Open
View article: <i>In Situ</i> Genetically Cascaded Amplification for Imaging RNA Subcellular Locations
<i>In Situ</i> Genetically Cascaded Amplification for Imaging RNA Subcellular Locations Open
In situ amplification methods, such as hybridization chain reaction, are valuable tools for mapping the spatial distribution and subcellular location of target analytes. However, the live-cell applications of these methods are still…
View article: Quantifying Tensile Forces at Cell–Cell Junctions with a DNA-based Fluorescent Probe
Quantifying Tensile Forces at Cell–Cell Junctions with a DNA-based Fluorescent Probe Open
SUMMARY Cells are physically contacting with each other. Direct and precise quantification of forces at cell–cell junctions is still challenging. Herein, we have developed a DNA-based ratiometric fluorescent probe, termed DNAMeter, to quan…
View article: Paper-based fluorogenic RNA aptamer sensors for label-free detection of small molecules
Paper-based fluorogenic RNA aptamer sensors for label-free detection of small molecules Open
A paper-based portable fluorogenic RNA sensor for the selective, sensitive, and rapid detection of target analytes.
View article: Quantifying tensile forces at cell–cell junctions with a DNA-based fluorescent probe
Quantifying tensile forces at cell–cell junctions with a DNA-based fluorescent probe Open
A DNA-based fluorescent probe to quantify the magnitude and distribution of tensile forces at cell–cell junctions.
View article: Lipid–oligonucleotide conjugates for simple and efficient cell membrane engineering and bioanalysis
Lipid–oligonucleotide conjugates for simple and efficient cell membrane engineering and bioanalysis Open
View article: Genetically Encoded Ratiometric RNA‐Based Sensors for Quantitative Imaging of Small Molecules in Living Cells
Genetically Encoded Ratiometric RNA‐Based Sensors for Quantitative Imaging of Small Molecules in Living Cells Open
Precisely determining the intracellular concentrations of metabolites and signaling molecules is critical in studying cell biology. Fluorogenic RNA‐based sensors have emerged to detect various targets in living cells. However, it is still …
View article: A quantitative assessment of the dynamic modification of lipid–DNA probes on live cell membranes
A quantitative assessment of the dynamic modification of lipid–DNA probes on live cell membranes Open
A comprehensive and quantitative study of the dynamic process of lipid–DNA conjugate modification onto cell membranes.
View article: Some Bounds on the Energy of Signed Complete Bipartite Graphs
Some Bounds on the Energy of Signed Complete Bipartite Graphs Open
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