Yasuyuki Kurihara
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View article: Revisiting the in vivo Functions of Coilin in Mice
Revisiting the in vivo Functions of Coilin in Mice Open
Cajal bodies (CBs), first identified in the early 20th century, are classic nuclear structures organized primarily by the protein coilin. Although CBs have long been implicated in snRNA modification and maturation, their precise roles in m…
View article: Clinical Application of Artificial Intelligence in Radiologic Imaging at Our Institution: Focusing on Thoracic Imaging
Clinical Application of Artificial Intelligence in Radiologic Imaging at Our Institution: Focusing on Thoracic Imaging Open
View article: COXFA4L3 enhances mitochondrial complex IV function to boost ATP synthesis and drive sperm motility
COXFA4L3 enhances mitochondrial complex IV function to boost ATP synthesis and drive sperm motility Open
COXFA4L3 is a testis-specific cytochrome c oxidase subunit that enhances mitochondrial complex IV activity during spermatogenesis. From the analysis of Coxfa4l3 knockout mice, the isoform switch from COXFA4 to COXFA4L3 may increase the pot…
View article: Efficacy and safety of drospirenone as a progestin‐only pill in Japanese women: A phase <scp>III</scp> study
Efficacy and safety of drospirenone as a progestin‐only pill in Japanese women: A phase <span>III</span> study Open
Aim To evaluate the efficacy and safety of 4 mg of drospirenone (DRSP), a progestin‐only pill (POP), for contraception in Japanese women. Methods This was a multicenter, open‐label, single‐arm study. The dosing period of DRSP was 13 cycles…
View article: Clinical and radiological features of gastric and small intestinal anisakiasis: comparison with gastric ulcers and crohn’s disease
Clinical and radiological features of gastric and small intestinal anisakiasis: comparison with gastric ulcers and crohn’s disease Open
View article: Immunohistochemistry of p53 surrogates TP53 mutation as an accurate predictor for early-relapse of surgically resected stage I-III lung adenocarcinoma
Immunohistochemistry of p53 surrogates TP53 mutation as an accurate predictor for early-relapse of surgically resected stage I-III lung adenocarcinoma Open
View article: Bilateral thoracotomy for horseshoe lung complicated with severe aspergilloma: a case report
Bilateral thoracotomy for horseshoe lung complicated with severe aspergilloma: a case report Open
Background Horseshoe lung is a rare congenital malformation in which the lung protrudes from the mediastinum to the other side. Owing to the high frequency of other fatal cardiovascular complications, it is often diagnosed in childhood and…
View article: Multimodal modeling with low-dose CT and clinical information for diagnostic artificial intelligence on mediastinal tumors: a preliminary study
Multimodal modeling with low-dose CT and clinical information for diagnostic artificial intelligence on mediastinal tumors: a preliminary study Open
Background Diagnosing mediastinal tumours, including incidental lesions, using low-dose CT (LDCT) performed for lung cancer screening, is challenging. It often requires additional invasive and costly tests for proper characterisation and s…
View article: Ectopic expression of the mitochondrial protein COXFA4L3 in human sperm acrosome and its potential application in the selection of male infertility treatments
Ectopic expression of the mitochondrial protein COXFA4L3 in human sperm acrosome and its potential application in the selection of male infertility treatments Open
Purpose Spermatogenesis requires a large amount of energy, which is primarily produced by the mitochondrial electron transfer chain. Mitochondrial dysfunction affects male infertility, suggesting a relationship between the electron transfe…
View article: Correction to: Clinical and imaging features of interstitial lung disease in cancer patients treated with trastuzumab deruxtecan
Correction to: Clinical and imaging features of interstitial lung disease in cancer patients treated with trastuzumab deruxtecan Open
View article: Review of clinical and diagnostic imaging of the thymus: from age-related changes to thymic tumors and everything in between
Review of clinical and diagnostic imaging of the thymus: from age-related changes to thymic tumors and everything in between Open
View article: Clinical and imaging features of interstitial lung disease in cancer patients treated with trastuzumab deruxtecan
Clinical and imaging features of interstitial lung disease in cancer patients treated with trastuzumab deruxtecan Open
View article: Short-term inhalation of sargramostim with concomitant high-dose steroids does not hasten recovery in moderate COVID-19 pneumonia: a double-blind, randomised, placebo-controlled trial
Short-term inhalation of sargramostim with concomitant high-dose steroids does not hasten recovery in moderate COVID-19 pneumonia: a double-blind, randomised, placebo-controlled trial Open
Granulocyte-macrophage colony stimulating factor (GM-CSF) inhalation may alleviate pulmonary inflammation caused by viral pneumonia. To investigate this, we evaluated its efficacy on COVID-19 pneumonia. This double-blind, randomised, place…
View article: Improvement of Fatigue Crack Propagation Property in Low Carbon Steel by Microstructural Control and an Investigation of its Practical Benefit
Improvement of Fatigue Crack Propagation Property in Low Carbon Steel by Microstructural Control and an Investigation of its Practical Benefit Open
The fatigue crack propagation properties of newly-developed SM490 grade steels were investigated in comparison with a conventional steel of the same grade. The fatigue crack propagation rate of the developed steel in Region II of the da/dN…
View article: Correction: Clinicopathological and ultrasound characteristics of breast cancer in BRCA1 and BRCA2 mutation carriers
Correction: Clinicopathological and ultrasound characteristics of breast cancer in BRCA1 and BRCA2 mutation carriers Open
View article: Intravascular large B-cell lymphoma appearance on dual-energy computed tomography: a case report
Intravascular large B-cell lymphoma appearance on dual-energy computed tomography: a case report Open
Background Intravascular large B-cell lymphoma (IVLBCL) is the proliferation of neoplastic B lymphocytes in the vascular space. Since conventional computed tomography (CT) shows nonspecific findings, differentiation between IVLBCL and othe…
View article: Rapid, simple, and effective strategy to produce monoclonal antibodies targeting protein structures using hybridoma technology
Rapid, simple, and effective strategy to produce monoclonal antibodies targeting protein structures using hybridoma technology Open
View article: Clinicopathological and ultrasound characteristics of breast cancer in BRCA1 and BRCA2 mutation carriers
Clinicopathological and ultrasound characteristics of breast cancer in BRCA1 and BRCA2 mutation carriers Open
View article: Deep Learning for Differentiation of Breast Masses Detected by Screening Ultrasound Elastography
Deep Learning for Differentiation of Breast Masses Detected by Screening Ultrasound Elastography Open
Recently, deep learning using convolutional neural networks (CNNs) has yielded consistent results in image-pattern recognition. This study was aimed at investigating the effectiveness of deep learning using CNNs to differentiate benign and…
View article: The location of unilateral axillary lymphadenopathy after COVID-19 vaccination compared with that of metastasis from breast cancer without vaccination
The location of unilateral axillary lymphadenopathy after COVID-19 vaccination compared with that of metastasis from breast cancer without vaccination Open
Purpose Unilateral axillary lymphadenopathy is known to occur after coronavirus disease (COVID-19) vaccination. Post-vaccination lymphadenopathy may mimic the metastatic lymph nodes in breast cancer, and it is challenging to distinguish be…
View article: Improvement of Fatigue Crack Propagation Property in Low Carbon Steel by Microstructural Control and an Investigation of its Practical Benefit
Improvement of Fatigue Crack Propagation Property in Low Carbon Steel by Microstructural Control and an Investigation of its Practical Benefit Open
The fatigue crack propagation properties of newly-developed SM490 grade steels were investigated in comparison with a conventional steel of the same grade. The fatigue crack propagation rate of the developed steel in Region II of the da/dN…
View article: Rapid, simple, and effective strategy to produce monoclonal antibodies targeting native protein structures using hybridoma technology
Rapid, simple, and effective strategy to produce monoclonal antibodies targeting native protein structures using hybridoma technology Open
BACKGROUND: Monoclonal antibodies are essential in life science research and developing antibody drugs and test drugs. Various methods have been developed to obtain monoclonal antibodies, among which hybridoma technology continues to be wi…
View article: Resection of blastomatoid pulmonary carcinosarcoma in an elderly man
Resection of blastomatoid pulmonary carcinosarcoma in an elderly man Open
背景．肺原発癌肉腫は，非小細胞癌（上皮性腫瘍成分）と異所性成分を含む肉腫（非上皮性腫瘍成分）が混在した悪性腫瘍で，肺悪性腫瘍全体の0.1-0.4%を占める肉腫様癌のうち，わずか4%とまれな腫瘍である．また芽腫様亜型は，上皮性成分に高悪性度胎児型腺癌を含む癌肉腫であり，肺芽腫との鑑別を要する．症例．81歳男性．検診で胸部異常陰影を指摘，CTガイド下針生検で扁平上皮癌を認め，一部に小細胞癌の混在が疑われた．右下葉肺癌（cT4N0M0, stageIIIA）の診断で右肺下葉切除術…
View article: Visual classification of three computed tomography lung patterns to predict prognosis of COVID-19: a retrospective study
Visual classification of three computed tomography lung patterns to predict prognosis of COVID-19: a retrospective study Open
View article: A retrospective study on radiological findings of diffuse pleural thickening with benign asbestos pleural effusion in Japanese cases
A retrospective study on radiological findings of diffuse pleural thickening with benign asbestos pleural effusion in Japanese cases Open
The requirement for compensation for diffuse pleural thickening in benign asbestos pleural effusion include five computed tomography findings of organized pleural effusion: [1] heterogeneity in the pleural effusion, [2] declined chest capa…
View article: Visual Classification of Three Computed Tomography Lung Patterns to Predict Prognosis of COVID-19: A Retrospective Study
Visual Classification of Three Computed Tomography Lung Patterns to Predict Prognosis of COVID-19: A Retrospective Study Open
Background : Quantitative evaluation of radiographic images has been developed and suggested for the diagnosis of coronavirus disease 2019 (COVID-19). However, there are limited opportunities to use these image-based diagnostic indices in …
View article: Rapid and reliable hybridoma screening method that is suitable for production of functional structure-recognizing monoclonal antibody
Rapid and reliable hybridoma screening method that is suitable for production of functional structure-recognizing monoclonal antibody Open
View article: Left omental artery bleeding in two patients with segmental arterial mediolysis successfully isolated with coil embolization
Left omental artery bleeding in two patients with segmental arterial mediolysis successfully isolated with coil embolization Open
View article: A case of resected primary pulmonary pleomorphic carcinoma with long-term survival after multidisciplinary treatment
A case of resected primary pulmonary pleomorphic carcinoma with long-term survival after multidisciplinary treatment Open
Background Generally, primary pulmonary pleomorphic carcinoma is resistant to treatment and has a poor prognosis. We report a case of resected primary pulmonary pleomorphic carcinoma with long-term survival after multidisciplinary treatmen…
View article: Sclerosing thymoma followed up for eight years as mediastinal goiter: A case report
Sclerosing thymoma followed up for eight years as mediastinal goiter: A case report Open