Huijun Li
YOU?
Author Swipe
View article: Association of circadian-metabolic syndrome with incident chronic liver disease in middle-aged and elderly Chinese adults: a prospective cohort study on mediation by cardiovascular disease
Association of circadian-metabolic syndrome with incident chronic liver disease in middle-aged and elderly Chinese adults: a prospective cohort study on mediation by cardiovascular disease Open
View article: A clinically translatable 2.5D lung adenocarcinoma organoid platform derived from malignant pleural effusions for precision drug screening and tumor-immune-stromal modeling
A clinically translatable 2.5D lung adenocarcinoma organoid platform derived from malignant pleural effusions for precision drug screening and tumor-immune-stromal modeling Open
Conventional three-dimensional (3D) organoid models are limited by high cost, technical complexity, and poor replication of tumor-immune interactions. To address these limitations, we developed two novel 2.5D systems from malignant pleural…
View article: Associations between meteorological factors and scrub typhus incidence: a systematic review and meta-analysis of linear and nonlinear dose–response relationships
Associations between meteorological factors and scrub typhus incidence: a systematic review and meta-analysis of linear and nonlinear dose–response relationships Open
View article: Strategies for Obtaining High-Performance Li-Ion Solid-State Electrolytes for Solid-State
Strategies for Obtaining High-Performance Li-Ion Solid-State Electrolytes for Solid-State Open
View article: Explainable machine learning-enabled dual-objective design of γ' phase characteristic parameters in γ'-strengthened Co-based superalloys
Explainable machine learning-enabled dual-objective design of γ' phase characteristic parameters in γ'-strengthened Co-based superalloys Open
The high-temperature performance of Co-based superalloys is primarily dictated by the coarsening kinetics and volume fraction of the γ′ phase. To simultaneously optimize these two interrelated microstructural parameters, we propose a dual-…
View article: A non-invasive phase current reconstruction strategy for three - level inverters with fixed sampling instants
A non-invasive phase current reconstruction strategy for three - level inverters with fixed sampling instants Open
View article: Developmental arrest of astrocyte lineage in Snai2 deletion mice: implication for the intellectual disability in patients with Waardenburg syndrome
Developmental arrest of astrocyte lineage in Snai2 deletion mice: implication for the intellectual disability in patients with Waardenburg syndrome Open
View article: Risk factors for steroid-refractory in immune checkpoint inhibitor-induced colitis: a retrospective cohort study
Risk factors for steroid-refractory in immune checkpoint inhibitor-induced colitis: a retrospective cohort study Open
Background Immune checkpoint inhibitors (ICIs) represent an effective treatment for various malignant tumors. However, the utilization of ICIs is frequently accompanied by immune-related adverse events (irAEs), among which immune checkpoin…
View article: Hierarchically aligned SiC whisker in polymer composites for enhancing mechanical and surface breakdown strength
Hierarchically aligned SiC whisker in polymer composites for enhancing mechanical and surface breakdown strength Open
View article: Updated efficacy and predictive biomarkers of QL1706, a bifunctional PD-1/CTLA-4 dual blocker in advanced solid tumors—A phase 1/1b study
Updated efficacy and predictive biomarkers of QL1706, a bifunctional PD-1/CTLA-4 dual blocker in advanced solid tumors—A phase 1/1b study Open
QL1706 has shown promising efficacy in solid tumors in a phase 1/1b study. Here, we report updated long-term survival outcomes and biomarker analyses. Among 468 patients treated with QL1706 (5 mg/kg), median progression-free survival (mPFS…
View article: Needle-like χ phase precipitation induced by stacking fault in novelCo-based superalloys
Needle-like χ phase precipitation induced by stacking fault in novelCo-based superalloys Open
View article: Effect of Carbonation-Treated Recycled Aggregates on the Properties of Permeable Geopolymer Concrete
Effect of Carbonation-Treated Recycled Aggregates on the Properties of Permeable Geopolymer Concrete Open
To address technical challenges such as the high water absorption of recycled aggregates (RA) and the lowmechanical performance of permeable concrete, this study systematically investigates the optimization of carbonationmodification proce…
View article: Transient Atom-Economy Utilization of Residual Binder for Upcycling the Spent LiFePO <sub>4</sub> Cathodes
Transient Atom-Economy Utilization of Residual Binder for Upcycling the Spent LiFePO <sub>4</sub> Cathodes Open
View article: Low‐Activation Compositionally Complex Alloys for Advanced Nuclear Applications—A Review
Low‐Activation Compositionally Complex Alloys for Advanced Nuclear Applications—A Review Open
View article: Microstructural characteristics of W-Cu composite prepared through novel plasma transferred arc welding technique
Microstructural characteristics of W-Cu composite prepared through novel plasma transferred arc welding technique Open
View article: CD68 as a multi-omic prognostic biomarker in digestive system cancers: correlations with tumor-infiltrating immune cells and immune checkpoints
CD68 as a multi-omic prognostic biomarker in digestive system cancers: correlations with tumor-infiltrating immune cells and immune checkpoints Open
Background and objective CD68 plays a crucial role in promoting phagocytosis. However, its expression level, prognostic value and the correlations with tumor-infiltrating immune cells (TIICs) or common tumor immune checkpoints (TICs) in hu…
View article: Exploring the role of circ-GALK2 in vascular smooth muscle cell calcification: mechanisms and implications
Exploring the role of circ-GALK2 in vascular smooth muscle cell calcification: mechanisms and implications Open
The current study elucidates the unique expression and critical function of the circ-GALK2/miR-134-3p/CD36 axis in vascular smooth muscle calcification, potentially offering significant insights for developing strategies to mitigate the pr…
View article: Exosomal gene signature in esophageal carcinoma: Insights from single-cell and bulk RNA sequencing
Exosomal gene signature in esophageal carcinoma: Insights from single-cell and bulk RNA sequencing Open
View article: Correction: tRF-1:28-Val-CAC-2 promotes the development of nasopharyngeal cancer by targeting EPHB2
Correction: tRF-1:28-Val-CAC-2 promotes the development of nasopharyngeal cancer by targeting EPHB2 Open
[This corrects the article DOI: 10.3389/fonc.2025.1564601.].
View article: Microstructural Characteristics of WC-Cu Cladding on Mild Steel Substrate Prepared Through Plasma Transferred Arc Welding
Microstructural Characteristics of WC-Cu Cladding on Mild Steel Substrate Prepared Through Plasma Transferred Arc Welding Open
This study explores the development of a novel composite coating system combining the high hardness of WC and thermal conductivity of Cu, employing the plasma transfer arc welding method under ambient conditions. Utilizing an advanced weld…
View article: Using journey mapping to understand the experience and need for patients with chimeric antigen receptor T-cell therapy
Using journey mapping to understand the experience and need for patients with chimeric antigen receptor T-cell therapy Open
The experiences and multidimensional care needs of patients receiving CAR-T cell therapy vary at different stages of treatment. Therefore, it is essential that health care professionals provide attention and support at these times. Patient…
View article: Performance validation of microchannel heat sinks based on single/multiobjective topology optimization and manufactured by selective laser melting
Performance validation of microchannel heat sinks based on single/multiobjective topology optimization and manufactured by selective laser melting Open
This study presents the design and experimental validation of two-dimensional (2D) and pseudo three-dimensional (P3D) microchannel heat sinks optimized through single-objective and multiobjective topology optimization via the solid isotrop…
View article: A lightweight neural radiance field model with automatic semantic segmentation for post‐earthquake building three‐dimensional reconstruction
A lightweight neural radiance field model with automatic semantic segmentation for post‐earthquake building three‐dimensional reconstruction Open
Earthquake can cause severe urban damage and economic losses, making the rapid, accurate, and safe exploration of building damage and preservation of on‐site earthquake data critical components. Deep learning‐based post‐earthquake technolo…
View article: Influence of selective laser melting process parameters on the microstructure, corrosion resistance, and mechanical properties of 2205 duplex stainless steel
Influence of selective laser melting process parameters on the microstructure, corrosion resistance, and mechanical properties of 2205 duplex stainless steel Open
View article: The extreme depletion of ionospheric electron density and its hemispheric asymmetry during the May 2024 storm
The extreme depletion of ionospheric electron density and its hemispheric asymmetry during the May 2024 storm Open
The Earth's ionosphere plays a critical role in radio wave transmission, reflection, and scattering, directly affecting communication, navigation, and positioning systems. However, the comprehensive impacts of space weather remain to be fu…
View article: Research Status and Advancements in Post-Acute Pancreatitis Diabetes Mellitus
Research Status and Advancements in Post-Acute Pancreatitis Diabetes Mellitus Open
Acute pancreatitis (AP), a common cause of acute abdominal pain in gastrointestinal disorders, is characterized by acute non-bacterial inflammation and acinar cell damage within the pancreas. As a heterogeneous disease, acute pancreatitis …
View article: Deciphering Short-Range Order Driven Mechanical Enhancement in CrTaTiMo Refractory Alloys via Machine-learning Potential and Experimental Validation
Deciphering Short-Range Order Driven Mechanical Enhancement in CrTaTiMo Refractory Alloys via Machine-learning Potential and Experimental Validation Open
Refractory high and medium entropy alloys (RH/MEAs) are promising for extreme environments owing to their superior long-term oxidation resistance and mechanical strength. In these alloys, short-range order (SRO) is a critical structural fe…
View article: Impact of pitch fraction oxidation on the structure and sodium storage properties of derived carbon materials
Impact of pitch fraction oxidation on the structure and sodium storage properties of derived carbon materials Open
View article: Microstructural Characteristics of WC‐Cu Cladding on Mild Steel Substrate Prepared Through Plasma Transferred Arc Welding
Microstructural Characteristics of WC‐Cu Cladding on Mild Steel Substrate Prepared Through Plasma Transferred Arc Welding Open
In this study, a WC-Cu composite coating was successfully fabricated on a mild steel substrate using the novel Plasma Transferred Arc (PTA) welding technique. Phase identification was carried out using X-ray diffraction (XRD), while micros…
View article: A conserved small RNA-generating gene cluster undergoes sequence diversification and contributes to plant immunity
A conserved small RNA-generating gene cluster undergoes sequence diversification and contributes to plant immunity Open
Small RNA-mediated gene silencing contributes to plant immunity. The secondary small interfering RNA (siRNA) pathway promotes defense by silencing target genes in invading fungal and oomycete pathogens. Many secondary siRNAs derive from tr…