Qiang Yang
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View article: From traditional medicinal use to functional food: The pharmacological activity, hepatotoxicity mechanism and detoxification strategies of gardenia fructus
From traditional medicinal use to functional food: The pharmacological activity, hepatotoxicity mechanism and detoxification strategies of gardenia fructus Open
Gardenia fructus (GF), a medicinal and edible herb with over 2,000 years of use, possesses diverse bioactive compounds including iridoids, crocins, and organic acids. Herein, we summarize the ethnomedicinal applications, phytochemistry, ph…
View article: SenWave: A Fine-Grained Multi-Language Sentiment Analysis Dataset Sourced from COVID-19 Tweets
SenWave: A Fine-Grained Multi-Language Sentiment Analysis Dataset Sourced from COVID-19 Tweets Open
The global impact of the COVID-19 pandemic has highlighted the need for a comprehensive understanding of public sentiment and reactions. Despite the availability of numerous public datasets on COVID-19, some reaching volumes of up to 100 b…
View article: Environmental greenness, physical activity, and their synergistic effects on vital capacity weight index in children and adolescents exposed to PM2.5 and O3 in economically developed provinces of China
Environmental greenness, physical activity, and their synergistic effects on vital capacity weight index in children and adolescents exposed to PM2.5 and O3 in economically developed provinces of China Open
Background The Vital Capacity Weight Index (VCWI) serves as a pivotal indicator of cardiopulmonary function among children and adolescents, reflecting their tissue oxygenation capacity and athletic potential. This study delves into the inf…
View article: Loss of tight junction protein claudin 18 uncovers alveolar epithelial stem cell plasticity and emergence of non-fibrogenic transitional progenitors
Loss of tight junction protein claudin 18 uncovers alveolar epithelial stem cell plasticity and emergence of non-fibrogenic transitional progenitors Open
SUMMARY Persistence of senescent alveolar transitional progenitors following lung injury is implicated in the pathogenesis of fibrosis. We identified transitional cells in uninjured Cldn18 knockout (KO) mouse lungs distinct from previously…
View article: Sales Prediction Based on Textual Features of Online Product Reviews
Sales Prediction Based on Textual Features of Online Product Reviews Open
Accurate sales forecasting is essential for effective enterprise decision-making. Reliable predictions not only optimize inventory management and reduce resource waste but also enhance customer experience. While prior research has primaril…
View article: The Relationship Between Non-Invasive Tests and Digital Pathology for Quantifying Liver Fibrosis in MASLD
The Relationship Between Non-Invasive Tests and Digital Pathology for Quantifying Liver Fibrosis in MASLD Open
Background: It is crucial to evaluate liver fibrosis in metabolic dysfunction-associated steatotic liver disease (MASLD). Digital pathology, an automated method for quantitative fibrosis measurement, provides valuable support to pathologis…
View article: Higher Food Inflammation Index Is Linearly Associated With Higher Risk of <scp>MASLD</scp> : A Cross‐Sectional Study Based on the <scp>NHANES</scp> (1999–2020)
Higher Food Inflammation Index Is Linearly Associated With Higher Risk of <span>MASLD</span> : A Cross‐Sectional Study Based on the <span>NHANES</span> (1999–2020) Open
Metabolic dysfunction‐associated steatotic liver disease (MASLD) is a major global chronic liver condition, with diet‐induced inflammation playing a key role in its pathogenesis. This study used 1999–2020 National Health and Nutrition Exam…
View article: Metabolite‐Guided Acetylation Therapy: Astragaloside IV Reverses Diabetic Nephropathy via Gna13‐Driven Purine Metabolic Reprogramming
Metabolite‐Guided Acetylation Therapy: Astragaloside IV Reverses Diabetic Nephropathy via Gna13‐Driven Purine Metabolic Reprogramming Open
Diabetic nephropathy (DN) exhibits profound metabolic dysregulation, yet the spatial organization and posttranslational control of pathogenic pathways remain poorly understood. This study integrates high‐resolution MALDI mass spectrometry …
View article: V‐UNet: Medical Image Segmentation Based on Variational Attention Mechanism
V‐UNet: Medical Image Segmentation Based on Variational Attention Mechanism Open
Accurate medical image segmentation plays a crucial role in improving the precision of computer‐aided diagnosis. However, complex boundary shapes, low contrast and blurred anatomical structures make fine‐grained segmentation a challenging …
View article: Prognostic role and functional impact of cadherin genes in non-small cell lung cancer tumorigenesis: mechanistic insights from <i>in silico</i> and <i>in vitro</i> analyses
Prognostic role and functional impact of cadherin genes in non-small cell lung cancer tumorigenesis: mechanistic insights from <i>in silico</i> and <i>in vitro</i> analyses Open
Non-small cell lung cancer (NSCLC) is a leading cause of cancer-related mortality worldwide, with poor prognosis and limited treatment options for advanced stages. Dysregulation of cadherin expression has been implicated in various cancers…
View article: Becoming the "Cool Aunt": Commodifying Female Independence in Xiaohongshu’s Xiaoyi Trend
Becoming the "Cool Aunt": Commodifying Female Independence in Xiaohongshu’s Xiaoyi Trend Open
The “cool aunt” archetype has gained cultural traction across global digital platforms, symbolizing a form of female autonomy outside traditional roles of marriage and motherhood. In China, this aspiration has materialized into the “Xiaoyi…
View article: Deciphering the Interplay between Attack and Protection Complexity in Privacy-Preserving Federated Learning
Deciphering the Interplay between Attack and Protection Complexity in Privacy-Preserving Federated Learning Open
Federated learning (FL) offers a promising paradigm for collaborative model training while preserving data privacy. However, its susceptibility to gradient inversion attacks poses a significant challenge, necessitating robust privacy prote…
View article: GIN-CRC-Pareto: A graph-based Pareto-optimal multi-task learning framework to identify miRNA-target interactions in colorectal cancer
GIN-CRC-Pareto: A graph-based Pareto-optimal multi-task learning framework to identify miRNA-target interactions in colorectal cancer Open
Colorectal cancer (CRC) ranks as the third highest incidence among malignancies in humans and the second most common cause of cancer-related mortality in the United States. Accumulating evidence has established microRNAs (miRNAs) as critic…
View article: Extremely Large-Scale Dynamic Metasurface Antennas for 6G Near-Field Networks: Opportunities and Challenges
Extremely Large-Scale Dynamic Metasurface Antennas for 6G Near-Field Networks: Opportunities and Challenges Open
6G networks will need to support higher data rates, high-precision localization, and imaging capabilities. Near-field technologies, enabled by extremely large-scale (XL)-arrays, are expected to be essential physical-layer solutions to meet…
View article: Integrative network pharmacology and multi-omics to investigate the potential mechanisms involved in Wumei Wan treatment of colorectal adenomas
Integrative network pharmacology and multi-omics to investigate the potential mechanisms involved in Wumei Wan treatment of colorectal adenomas Open
Background Wumei Wan (WMW), a classical Traditional Chinese Medicine (TCM) formulation, has been employed for treating colorectal adenoma (CRA), yet its pharmacological mechanisms remain to be elucidated. This study investigated the protec…
View article: HtFLlib: A Comprehensive Heterogeneous Federated Learning Library and Benchmark
HtFLlib: A Comprehensive Heterogeneous Federated Learning Library and Benchmark Open
As AI evolves, collaboration among heterogeneous models helps overcome data scarcity by enabling knowledge transfer across institutions and devices. Traditional Federated Learning (FL) only supports homogeneous models, limiting collaborati…
View article: Assessment of Lithium-ion Battery Controllable Capacity Based on CNN-BiLSTM-Attention
Assessment of Lithium-ion Battery Controllable Capacity Based on CNN-BiLSTM-Attention Open
To overcome the limitations of low accuracy in lithium-ion battery controllable capacity assessment using a single data-driven method, this paper introduces a novel CNN-BiLSTM-Attention model. Firstly, health features pertinent to battery …
View article: Spatially segregated multiomics decodes metformin-mediated functional-specific metabolic characteristics in diabetic kidney disease
Spatially segregated multiomics decodes metformin-mediated functional-specific metabolic characteristics in diabetic kidney disease Open
Understanding the specific metabolic changes in multiple regions of the kidney is crucial to revealing the underlying mechanism and developing effective targets for diabetic nephropathy (DN). In this study, integrated spatially resolved me…
View article: The relationship between dietary index for gut microbiota and hyperuricemia: a cross-sectional study using NHANES data
The relationship between dietary index for gut microbiota and hyperuricemia: a cross-sectional study using NHANES data Open
Background Hyperuricemia (HUA) is a common metabolic disorder, yet the impact of diet and gut microbiota on uric acid metabolism remains insufficiently understood. This study aims to investigate the relationship between the dietary index f…
View article: INFERENCEDYNAMICS: Efficient Routing Across LLMs through Structured Capability and Knowledge Profiling
INFERENCEDYNAMICS: Efficient Routing Across LLMs through Structured Capability and Knowledge Profiling Open
Large Language Model (LLM) routing is a pivotal technique for navigating a diverse landscape of LLMs, aiming to select the best-performing LLMs tailored to the domains of user queries, while managing computational resources. However, curre…
View article: Occult: Optimizing Collaborative Communication across Experts for Accelerated Parallel MoE Training and Inference
Occult: Optimizing Collaborative Communication across Experts for Accelerated Parallel MoE Training and Inference Open
Mixture-of-experts (MoE) architectures could achieve impressive computational efficiency with expert parallelism, which relies heavily on all-to-all communication across devices. Unfortunately, such communication overhead typically constit…
View article: eSPred: Explainable scRNA-seq Prediction via Customized Foundation Models and Pathway-Aware Fine-tuning
eSPred: Explainable scRNA-seq Prediction via Customized Foundation Models and Pathway-Aware Fine-tuning Open
Single-cell RNA sequencing (scRNA-seq) has been widely used for studying cellular heterogeneity, but its use for subject-level prediction and clinical applications is still limited. We introduce eSPred, a customized foundation model design…
View article: Characterizing hub biomarkers for metabolic-induced endothelial dysfunction and unveiling their regulatory roles in EndMT through RNA sequencing and machine learning approaches
Characterizing hub biomarkers for metabolic-induced endothelial dysfunction and unveiling their regulatory roles in EndMT through RNA sequencing and machine learning approaches Open
Background Metabolic disorder and endothelial dysfunction (ED) are key events in the development and pathophysiology of atherosclerosis and are associated with an elevated risk of Cardiovascular disease (CVD). The pathophysiology remains i…
View article: Corrigendum to ‘Guideline for adolescent scoliosis screening in China (Public Version 2024)’ [J Orthop Translation, Volume 50, January 2025, Pages 364-372]
Corrigendum to ‘Guideline for adolescent scoliosis screening in China (Public Version 2024)’ [J Orthop Translation, Volume 50, January 2025, Pages 364-372] Open
[This corrects the article DOI: 10.1016/j.jot.2024.09.006.].